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Teleportation of a Coherent Superposition State Via a nonmaximally Entangled Coherent Xhannel

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量子光学学报 2002年第B09期8卷 19-20页

作者： ZHENF yi－xhuang gu Yong－jian 等 DepartmentofPhysics WenzhouNormalCollege，Wenzhou325027.R.China LaboratoryofQuantumCommunicationandQuantumComputation UniversityofScienceandTechnologyofXhinaHefei230026P.R.China

We investigate the problemm of teleportation of a superposition coherent state with nonmaximally entangled coherent channel. Two strategies are considered to complete the task. The first one uses entanglement concentration to purify the channel to a maximally entangled one. The second one teleports the state through the nonmaximally entangled coherent channel directly. We find that the probabilities of successful teleportations for the two strategies are depend on the amplitudes of the coherent states and the mean fidelity of teleportation using the first strategy is always less than that of the second strategy.

关键词：量子光学纠缠态纠缠播送量子信息一致叠加态

Sub-chronic Toxicity of Defoamer Used in Seawater Desalination

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Biomedical and Environmental Sciences 2019年第5期32卷 334-344页

作者： DUAN Lian ZHANG Chong Hua gu Wen ZHI Hong KONG jian ZHANG Shao Ping LI yi Min LU Kai Institute for Environmental Health and Related Product Safety Chinese Center for Disease Control and PreventionBeijing 100020China The Centers for Disease Control and Prevention Harbin Harbin 150000HeilongjiangChina Chinese Center for Disease Control and Prevention Beijing 102206China

Objective To explore the possible long‐term health effects of the defoamer used in seawater desalination by sub‐chronic toxicity testing. Methods Blood analysis, internal organ assessment, and histopathological examination were carried out in rats exposed to low, medium, and high(0.5, 1.0, and 2.0 g/kg BW, respectively) doses of defoamer for 90 days through oral administration. Results The high dose group showed decreased blood alanine aminotransferase and aspartate aminotransferase(P < 0.05). All doses resulted in a significant increase in albumin and decrease in globulin(P < 0.05). The direct bilirubin and indirect bilirubin were decreased in the medium and high dose groups(P < 0.05). All dose groups showed significant induction of alkaline phosphatase(P < 0.05). Pathological examination revealed a case of liver mononuclear cell infiltration in the medium dose group and three cases of liver congestion, steatosis of hepatic cells around the central vein, and punctate necrosis with multiple focal mononuclear cell infiltration in male rats administered the high dose. The No Observed Adverse Effect Level was 0.5 g/kg BW in rats, with albumin and total bilirubin as health effect indices. Conclusion Long‐term defoamer exposure may cause liver injury but has no significant impact on renal function in rats. The effect on blood cells in female rats was more prominent than that in male rats.

关键词： Seawater desalination Defoamer Sub‐chronic toxicity

Determination of Standard Molar Enthalpies of Formation for "White Powdery Tungstic Acid" and for Dodecatungstophosphoric Acid by Solution Calorimetry

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Chemical Research in Chinese Universities 1993年第1期9卷 13-17页

作者： WANG Ai-ming cai Xian-e ZHU Jing gu yi-dong(Department of Chemistry, Fudan University, Shanghai 200433)

'White powdery tungstic acid' has been used for preparing various types of tungsten-containing compounds due to its high reactivity. The present paper covers the standard molar enthalpies of formation, △H0/f of three tungsten- containing acids. The values found for 'white powdery tungstic acid' WO3·1. 68H2O, 'yellow tungstic acid' WO3·1. 20H2O and dodecatungstophosphoric acid H3(PW12O40)·25H2O at 298. 15 K were-(1312±1), - (1192±1) and -(18150±13) kJ mol-1, respectively.

关键词： Enthalpy of formation Tungstic acid Dodecatungstophosphoric acid Solution calorimetry

Long-term functional maintenance of primary hepatocytes in vitro using macroporous hydrogels engineered through liquid-liquid phase separation

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Nano Research 2024年第3期17卷 1725-1736页

作者： Yang Sun Sheng yin jian Cui Zhongxia Wang Yueying Han Ding Ma Shuo Wang Junhua Wu yi Cao Chunping jiang Xiaosong gu Jinan Microecological Biomedicine Shandong Laboratory Jinan 250021China Collaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State MicrostructureKey Laboratory of Intelligent Optical Sensing and ManipulationMinistry of EducationDepartment of PhysicsNanjing UniversityNanjing 210093China Department of Hepatobiliary Surgery The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210093China National Institute of Healthcare Data Science at Nanjing University Nanjing UniversityNanjing 210093China

Preserving the functionality of hepatocytes in vitro poses a significant challenge in liver tissue engineering and bioartificial liver,as these cells rapidly lose their metabolic and functional characteristics after *** by the macroporous structures found in native liver tissues,here we develop synthetic hydrogel scaffolds that closely mimic the liver’s structural organization through the phase separation between polyethylene glycol(PEG)and *** hydrogels exhibit interconnected macroporous structures and appropriate mechanical properties,providing an optimal microenvironment conducive to hepatocyte adhesion and the formation of sizable *** to two-dimensional hepatocyte cultures,enhanced functionalities of hepatocytes cultured in our macroporous hydrogels were observed for 14 days,as evidenced by quantitative reverse-transcription–polymerase chain reactions(qRT-PCR),immunofluorescence,and enzyme linked immunosorbent assay(ELISA)*** sequencing data further confirmed the establishment of cell–cell interactions among hepatocytes when cultured in our ***,these hepatocytes maintained a protein expression lineage that closely resembled freshly isolated hepatocytes,particularly in the Notch and tumor necrosis factor(TNF)signaling *** results suggest that the macroporous hydrogels are attractive scaffolds for liver tissue engineering.

关键词： liver tissue engineering phase separation hepatocytes macroporous hydrogel

PREPARATION OF ENANTIOMERICALLY PURE SYN-4,5-DIHYDROXY CARBOXYLIC ACID LACTONES BY MICROBIAL REDUCTION

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Chinese Chemical Letters 1991年第5期2卷 345-346页

作者： jian Xin gu Zu yi LI guo Qiang LIN Shanghai Institute of Organic Chemistry Academia Sinica 345 Lingling LuShanghai 200032

Enantiomerically pure syn-4,5-dihydroxy carboxylic acid lactones were prepared by microbial reduction of acyl lactones with resting cell of Aspergillus niger.

关键词： SYN PREPARATION OF ENANTIOMERICALLY PURE SYN-4,5-DIHYDROXY CARBOXYLIC ACID LACTONES BY MICROBIAL REDUCTION ACID

Targeting Erbin in B cells for therapy of lung metastasis of colorectal cancer

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Signal Transduction and Targeted Therapy 2021年第4期6卷 1302-1319页

作者： Tong Shen Jing-Lin Liu Chu-yi Wang Youlutuziayi Rixiati Shi Li Ling-Dong cai Yuan-Yuan Zhao jian-Ming Li Department of Pathology Soochow University Medical SchoolSuzhouChina Department of Pathology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouChina

The mechanisms and key factors involved in tumor environments for lung metastasis of CRC are still ***,using clinical samples from lung metastases of CRC patients,we found that intestinal immune network for IgA production was significantly dysregulated in lung metastases of ***-cell RNA sequencing discovered a subtype of B cells positive for Erbin,one member of the leucine-rich repeat and PDZ domain(LAP)family,was involved in the lung *** deletion in B cells suppressed lung metastasis of CRC in ***,deletion of Erbin in B cells enhanced the killing effects of CD8+T cells on tumor ***,Erbin knockout attenuated TGFp-mediated suppression of migration of CXCR5+lgA+cells and STAT6-mediated PD1 *** study uncovered a key role of Erbin in regulating PD1+lgA+B cells in lung metastasis of *** Erbin as well as combined use of neutralizing B cells and antibodies neutralizing PD1 suppresses lung metastasis of CRC in mice,suggesting the potential option for treatment of lung metastasis of CRC.

关键词： PD1 metastasis lung

Brain-derived neurotrophic factor protects against acrylamide-induced neuronal and synaptic injury via the TrkB-MAPK-Erk1/2 pathway

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Neural Regeneration Research 2021年第1期16卷 150-157页

作者： Xiao Chen Jing-Wei Xiao Peng Cao yi Zhang Wen-jian cai Jia-Yang Song Wei-Min Gao Bin Li Department of Toxicology Key Lab of Chemical Safety and HealthNational Institute of Occupational Health and Poison ControlChinese Center for Disease Control and PreventionBeijingChina Department of Occupational and Environmental Health Sciences School of Public HealthWest Virginia UniversityMorgantownWVUSA

Acrylamide has been shown to be ***-derived neurotrophic factor(BDNF)can alleviate acrylamide-induced synaptic injury;however,the underlying mechanism remains *** this study,dibutyryl-cyclic adenosine monophosphate-induced mature human neuroblastoma(NB-1)cells were exposed with 0–100μg/mL acrylamide for 24–72 *** decreased cell viability and destroyed *** of co-cultured NB-1 cells and Schwann cells to 0–100μg/mL acrylamide for 48 hours resulted in upregulated expression of synapsin I and BDNF,suggesting that Schwann cells can activate self-protection of *** co-culture conditions,activation of the downstream TrkB-MAPK-Erk1/2 pathway strengthened the protective *** BDNF can increase expression of TrkB,Erk1/2,and synapsin I,while exogenous BDNF or the TrkB inhibitor K252a could inhibit these *** together,Schwann cells may act through the BDNF-TrkB-MAPK-Erk1/2 signaling pathway,indicating that BDNF plays an important role in this ***,exogenous BDNF may be an effective treatment strategy for acrylamide-induced nerve *** study was approved by the Laboratory Animal Welfare and Ethics Committee of the National Institute of Occupational Health and Poison Control,a division of the Chinese Center for Disease Control and Prevention(approval ***-2017-008)on May 29,2017.

关键词： factor injury pathway peripheral nerve protection protein regeneration repair

Gecko crude peptides inhibit migration and lymphangiogenesis by down regulating the expression of VEGF-C in human hepatocellular carcinoma cells and human lymphatic endothelial cells

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中国药理学与毒理学杂志 2017年第10期31卷 958-959页

作者： Meng-li guO cai-e WANG yi-meng DUAN jian-gang WANG Medical College Henan University of Science and Technology The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology

OBJECTIVE To explore the role of gecko crude peptides(GCPs)in the proliferation,apoptosis,migration and lymphangiogenesis of human hepatocellular carcinoma cells(Hep G2)and human lymphaticendothelial cells(HLECs)in *** The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay was used to evaluate the anti-proliferative effect of GCPs and si RNA-VEGF-C on Hep G2 cells,Hoechst 33258 staining and flow cytometry were performed to analyze cycle and *** migration and invasion ability of cells were assayed by transwell chamber experiment and wound-healing *** protein and m RNA expressions of vascular endothelial growth factor-C(VEGF-C)and CXC chemokine receptor-4(CXCR4)were detected by q-PCR,immunofluorescence,Western *** protein expressions of the extracellular signal regulated kinase(ERKI/2),c-Jun N-terminal kinase(JNK),p38-mitogen activated protein kinases(p38 MAPK),serine/threonine kinase(Akt)and phosphatidylinositol-3-kinase(PI3K)were detected by western *** anti-lymphangiogenesis effect of GCPs on the HLECs was analyzed using an in vitro tube-formation *** protein and m RNA expressions of vascular endothelial growth factor receptor-3(VEGFR-3)and stromal cell-derived factor-1(SDF-1)were detected by q-PCR,Western *** GCPs and si RNA-VEGF-C inhibited Hep G2 proliferation,invasion and migration,and the most obvious inhibitory effect was both synergistic ***,GCPs suppressed HLECs proliferation,migration and tubelike structure formationin a dose-dependent manner,and had inhibitory effect of tumor-induced lymphangiogenesis in ***,we found that GCPs and si RNA-VEGF-C decreased the expressions of MMP-2,MMP-9,VEGF-C,CXCR4,phospho-ERK1/2,phospho-P38,phospho-JNK and PI3K in Hep G2 ***,GCPs had a dose-dependent depressive effecton the expressions of VEGFR-3,SDF-1 in *** The low expression of VEGF-C mediated by si RNA-VEGF-C and GCPs inhibit tumor proliferation,invas

关键词： gecko crude peptides hepatic carcinoma vascular endothelial growth factor-C RNA interference(RNAi) lymphangiogenesis

Radiomics in the diagnosis and treatment of hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2023年第4期22卷 346-351页

作者： Chun jiang yi-Qi cai Jia-Jia Yang Can-Yu Ma Jia-Xi Chen Lan Huang Ze Xiang jian Wu Department of Clinical Laboratory The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215008China Zhejiang University School of Medicine Hangzhou 310030China Department of Infection Management The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhou 215008China

Hepatocellular carcinoma(HCC)is a common malignant *** present,early diagnosis of HCC is dif-ficult and therapeutic methods are *** can achieve accurate quantitative evaluation of the lesions without invasion,and has important value in the diagnosis and treatment of *** fea-tures can predict the development of cancer in patients,serve as the basis for risk stratification of HCC patients,and help clinicians distinguish similar diseases,thus improving the diagnostic ***-more,the prediction of the treatment outcomes helps determine the treatment *** is also helpful in predicting the HCC recurrence,disease-free survival and overall *** review summa-rized the role of radiomics in the diagnosis,treatment and prognosis of HCC.

关键词： Hepatocellular carcinoma Radiomics Diagnosis Prognosis Treatment