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《寿世青编》食养食疗学术探讨

中国中医基础医学杂志 2021年第4期27卷 563-565页

作者：林基伟徐峰汪栋材吴海滨彭得倜郑浩涛孙晓生深圳市中医院深圳518000 广州中医药大学基础医学院广州510006

《寿世青编》是清代一部养生专著,该书重视饮食物的养生调护功效,特列“食疗秘方”“饮食禁忌节要”“服药忌食”等篇。本文从食养食疗视角对其养生学术思想及方法进行发凡,其内容包含食能养生、食亦害生、食能防病、食能治病、食可愈病... 详细信息

《寿世青编》是清代一部养生专著,该书重视饮食物的养生调护功效,特列“食疗秘方”“饮食禁忌节要”“服药忌食”等篇。本文从食养食疗视角对其养生学术思想及方法进行发凡,其内容包含食能养生、食亦害生、食能防病、食能治病、食可愈病,具体原则有食宜凡简、食应“节”“律”、食当应时,倡导素食、食后养生、瘥后服食。《寿世青编》总结了作者的临床经验及日常养生实践及饮食物的养生调护,其食疗养生思想对现代营养学、中医食疗学、药膳学等学科具有指导价值,对现代人的养生保健有一定的参考和现实意义。

关键词：寿世青编食疗食养养生尤乘

小檗碱和肉桂多酚联合使用可通过Bas-TGR5-GLP-1改善T2DM大鼠的葡萄糖代谢

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药学学报 2024年第1期59卷 135-142页

作者：刘万梁菲蔡铁全李莹李乐杨树才刘影赵妍哈尔滨医科大学黑龙江哈尔滨150076 国家市场监督管理总局食品评价中心北京100070

小檗碱(berberine,BBR)是黄连的主要活性成分,有降血糖作用,但由于口服生物利用度低,限制了其临床应用。肉桂(cinnamomum cassia,Cin)中的多酚成分,对2型糖尿病(T2DM)有益。二者联合应用可能会有相加的效果。本研究通过对糖尿病大鼠联... 详细信息

小檗碱(berberine,BBR)是黄连的主要活性成分,有降血糖作用,但由于口服生物利用度低,限制了其临床应用。肉桂(cinnamomum cassia,Cin)中的多酚成分,对2型糖尿病(T2DM)有益。二者联合应用可能会有相加的效果。本研究通过对糖尿病大鼠联合用药干预,探讨二者联合的降血糖作用效果及机制。将造模成功的大鼠随机分为5组[糖尿病对照组(Con)、小檗碱组(BBR)、肉桂多酚组(Cin)、联合组(BBR+Cin)、二甲双胍组(Met)]和正常对照组(Nor)。该动物实验得到了动物伦理委员会的批准(批准号:HMUIRB2022003)。经口给予受试物,对照组给予等体积溶剂,每周称量体重。给药30天后进行口服葡萄糖耐量实验和胰岛素敏感性实验,检测空腹血糖(FBG)、糖化血清蛋白(GSP)、血清胰岛素(INS)水平,采用高通量测序技术检测肠道菌群构成,实时荧光定量PCR(RT-qPCR)和蛋白免疫印迹(Western blot)分别检测肝脏和结肠组织中G蛋白偶联受体5(TGR5)和胰高血糖素样肽-1(GLP-1)的表达。结果显示,与模型对照组比较,联合组大鼠FBG(P<0.01)、GSP(P<0.01)水平降低,胰岛素抵抗改善,效果优于BBR组。联合处理增加了拟杆菌属、普雷沃菌属和乳杆菌属的相对丰度,逆转小檗碱单独诱导组的乳杆菌属减少的结果,且二者联合可促进TGR5和GLP-1的表达。综上,联合应用肉桂多酚和小檗碱比单独应用小檗碱能更好地调节糖代谢。小檗碱联合肉桂多酚可通过改变肠道菌群,增加TGR5和GLP-1蛋白表达,改善2型糖尿病大鼠胰岛β细胞功能,从而更好地调节糖代谢。

关键词：小檗碱肉桂多酚肠道菌群 2型糖尿病糖代谢

The electrical conductivity of eclogite in Tibet and its geophysical implications

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Science China Earth Sciences 2014年第9期57卷 2071-2078页

作者： GUO YingXing WANG DuoJun SHI YaoLin ZHOU YongSheng dong YongSheng LI cai Key Laboratory of Computational Geodynamics University of Chinese Academy of Sciences The State Key Laboratory of Earthquake Dynamics Institute of Geology China Earthquake Administration College of Earth Sciences Jilin University

The electrical conductivity of Tibetan eclogite was investigated at pressures of 1.5-3.5 GPa and temperatures of 500-803 K using impedance spectroscopy within a frequency range of 10-1 -10^6 Hz. The electrical conductivity of eclogite increases with increasing temperature （which can be approximated by the Arrhenius equation）, and is weakly affected by pressure. At each tested pressure, the electrical conductivity is weakly temperature dependent below -650 K and more strongly temperature de- pendent above -650 K. The calculated activation energies and volumes are 44±1 kJ/mol and -0.6±0.1 cm3/mol for low tem- peratures and 97±3 kJ/mol and -1.2±0.2 cm3/mol for high temperatures, respectively. When applied to the depth range of 45-100 km in Tibet, the laboratory data give conductivities on the order of 10^-15 -10^-4.5 S/m, within the range of geophysical conductivity profiles.

关键词： electrical conductivity high temperature and pressure eclogite

CEA、CA125、CA153、CYFRA 211在三阴型乳腺癌中的诊断价值评价

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热带医学杂志 2019年第9期19卷 1082-1085,1060页

作者：王海疆蔡栋昊栾艺罗晓红段朝晖中山大学孙逸仙纪念医院广东广州510120 惠州市中心人民医院广东惠州516000

目的探究癌胚抗原(CEA)、糖类抗原125(CA125)、糖类抗原153(CA153)、细胞角蛋白19片段(CYFRA211)在三阴型乳腺癌诊断中的应用价值,为三阴型乳腺癌的临床诊断提供辅助手段。方法回顾性分析264例三阴型乳腺癌患者、119例良性乳腺疾病及81... 详细信息

目的探究癌胚抗原(CEA)、糖类抗原125(CA125)、糖类抗原153(CA153)、细胞角蛋白19片段(CYFRA211)在三阴型乳腺癌诊断中的应用价值,为三阴型乳腺癌的临床诊断提供辅助手段。方法回顾性分析264例三阴型乳腺癌患者、119例良性乳腺疾病及81例健康体检者中CEA、CA125、CA153、CYFRA211的水平变化情况,应用ROC曲线评价其对三阴型乳腺癌的诊断效能。结果 CA125、CA153、CYFRA211均与肿瘤分期相关(P0.05)。通过ROC曲线发现CA125在三阴型乳腺癌中的诊断效能最好(AUC=0.830,P0.05)。联合CA125、CA153、CYFRA211诊断效能最高(AUC=0.857,P<0.05),可显著提升诊断特异性。结论 CA125是三阴型乳腺癌的有效诊断指标,联合CA125、CA153、CYFRA211可以显著提升诊断特异性。CA153、CYFRA211单一指标对三阴型乳腺癌的诊断效能一般,CEA对于三阴性乳腺癌诊断效能最差。

关键词：三阴型乳腺癌癌胚抗原糖类抗原125 糖类抗原153 细胞角蛋白19片段

基于光纤陀螺的堆石坝内部沉降分布式监测技术研究

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土木工程学报 2024年第2期57卷 77-86页

作者：廖铖蔡德所李苗林金城江西省水利科学院江西南昌330029 三峡大学湖北宜昌443002 江西水利职业学院江西南昌330013 中国电建集团贵阳勘测设计研究院有限公司贵州贵阳550081

针对传统堆石坝内部沉降监测技术已难于满足超高堆石坝内部沉降监测需求。文章开发了基于光纤陀螺仪(FOG)的堆石坝内部沉降分布式监测系统,该系统主要由监测管道、监测小车和牵引装置组成。推导FOG监测系统测量坝体内部沉降的原理,考虑... 详细信息

针对传统堆石坝内部沉降监测技术已难于满足超高堆石坝内部沉降监测需求。文章开发了基于光纤陀螺仪(FOG)的堆石坝内部沉降分布式监测系统,该系统主要由监测管道、监测小车和牵引装置组成。推导FOG监测系统测量坝体内部沉降的原理,考虑监测小车不匀速问题,建立监测小车运行速度函数关系,引进经验模态(EMD)-小波混合降噪方法滤除监测小车运行过程中的振动噪声和FOG漂移误差。该监测系统成功应用于猴子岩面板堆石坝。现场监测结果表明,FOG2次独立测量结果的相关系数为0.986,说明FOG监测系统工作性能稳定,与水管式沉降仪测量结果基本一致,验证了该系统的可行性和准确性。

关键词：堆石坝内部沉降光纤陀螺分布式监测经验模态-小波

Underwater Wet Welding for HSLA Steels: Chemical Composition, Defects, Microstructures, and Mechanical Properties

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Acta Metallurgica Sinica(English Letters) 2015年第9期28卷 1097-1108页

作者： Wen-Bin Gao dong-Po Wang Fang-Jie Cheng cai-Yan Deng Wei Xu Tianjin Key Laboratory of Advanced Joining Technology School of Materials Science and Engineering Tianjin University Offshore Oil Engineering Co. Ltd

The effect of water depth on underwater wet welds was investigated by underwater wet shielded metal-arc welding technique. The microstructures, chemical composition, welding defects, and mechanical properties were studied. The contents of alloying elements decrease, while the oxygen content increases with water depth. Within 55 m depth, the carbon monoxide reaction is controlling the oxygen content which will further control the contents of alloying elements. The columnar microstructures in weld metal obtained at shallow water consist of grain boundary ferrite, side-plate ferrite, and acicular ferrite, while those at depth greater than 11 m exhibit more proeutectoid ferrite due to the loss of alloying elements. Mechanical properties are a strong function of depth owing to the increase in oxidation of alloying elements and porosity. Welds obtained within 11 m show preferable strength, ductility, and toughness. The mechanical properties significantly drop from 11 to 25 m because of the increased porosity and oxidation of alloying elements.

关键词： Underwater wet welding Electrode High-strength steel Microstructures Mechanicalproperties

First Report of Sclerotium hydrophilum Causing Leaf Spot on Brasenia schreberi in Central China

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First Report of Sclerotium hydrophilum Causing Leaf Spot on ...

玉米赤霉烯酮对小鼠原代培养T淋巴细胞细胞因子分泌的影响

中国植物病理学会2024年学术年会

作者： FU Shiying YANG Shaoli ZHOU Lilin KUANG Jing WANG Pan ZHANG Jing cai Xiang Institute of Vegetable Wuhan Academy of Agriculture Science Hubei Key Laboratory of Plant Pathology Huazhong Agricultural University

Brasenia schreberi,commonly known as watershield and referred to as 'Chun cai' in Chinese,is a worldwide aquatic *** has long been regarded as health-promoting vegetable due to production of mucilage in young shoots,and thus has gained popularity in *** September 2022,a leaf spot disease was observed at the National Aquatic Vegetable Germplasm Resource Nursery located in Wuhan,Hubei province,*** disease occurred on watershield *** started with the formation of leaf spots surrounded by *** spots ranged in color from yellow to brown and in diameter from 1 mm to 10 ***,the smaller spots merged,ultimately causing the entire leaves to turn *** brown-to black-colored sclerotia were produced on the underside of the diseased *** incidence was 30% on average,and yield loss was approximately 15% on *** isolate the pathogen,leal tissues at the disease-healthy border area were excised into 5 mm×5 mm pieces,these segments were immersed in 75% ethanol for 30 s,followed by immersion in 0.5% sodium hypochlorite for 30 s,and then rinsed twice in sterile *** air-drying,the leaf pieces were incubated on potato dextrose agar(PDA) in darkness at 28℃ for 3 *** from the leaf pieces were transferred to new PDA plates for purification,three sclerotia-forming fungal isolates(Whcc-1,Whcc-3,Whcc-4) were finally *** were incubated on PDA at 28℃ for 4 d to 14 d for observation of colony *** 4 after incubation(DAI),they grew rapidly with the average growth rate of 2.2 cm/d and formed colonies with whitish substrate mycelia and well-developed aerial mycelia and small white to light brown-colored *** 10 to 14 DAI,the sclerotia gradually turned to black,0.2 mm to 0.4 mm in diameter(0.26 mm on average,n=50).These morphological characteristics matched description of Sclerotium hydrophilum(Bashyal et al.,2021).Molecular identification was done to further clarify the species identity of thi

关键词： Brasenia schreberi Sclerotium hydrophilum morphology pathogenicity phylogeny

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中国兽医学报 2019年第3期39卷 512-516页

作者：李茜蔡国栋常晓翠邹辉袁燕顾建红刘学忠刘宗平卞建春扬州大学兽医学院江苏扬州225009 江苏省动物重要疫病与人兽共患病防控协同创新中心江苏扬州225009

为探讨玉米赤霉烯酮(zearalenone,ZEA)对动物免疫功能的影响及其机理,试验以分离培养的原代小鼠脾脏淋巴细胞材料,研究了ZEA对T淋巴细胞细胞因子分泌的影响。以刀豆蛋白A(Con A,5 mg/L)作为T细胞活化特异性刺激剂,试验设空白对照组(不加... 详细信息

为探讨玉米赤霉烯酮(zearalenone,ZEA)对动物免疫功能的影响及其机理,试验以分离培养的原代小鼠脾脏淋巴细胞材料,研究了ZEA对T淋巴细胞细胞因子分泌的影响。以刀豆蛋白A(Con A,5 mg/L)作为T细胞活化特异性刺激剂,试验设空白对照组(不加Con A)、Con A组(5 mg/L Con A)、不同浓度的ZEA染毒组(Con A+ZEA 10、20和40μmol/L),处理48,72 h后,使用流式液相多重蛋白定量技术检测T细胞分泌IL-2、IL-3、IL-5、IL-6和GM-CSF等细胞因子的含量。结果显示,与空白对照组相比,Con A组细胞在48,72 h时间段5种细胞因子分泌均明显上升;与Con A组比较,染毒48,72 h后,10,20,40μmol/L ZEA染毒组各细胞因子分泌浓度均有极显著下降(P<0.01),并呈剂量-效应关系。结果表明,ZEA可以抑制T淋巴细胞细胞因子IL-2、IL-3、IL-5、IL-6和GM-CSF的分泌,从而影响机体正常免疫反应的进行,降低整体的免疫功能。

关键词：玉米赤霉烯酮 T淋巴细胞刀豆蛋白A 细胞因子流式液相多重蛋白定量技术

Halogen-Free Flame Retarded Poly(Lactic Acid)with an Isosorbide-Derived Polyphosphonate

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Journal of Renewable Materials 2022年第7期10卷 1875-1888页

作者： Wenwen Guo Wei cai dong Wang Junling Wang Xiefei Zhu Bin Fei Key Laboratory of Eco-Textiles Ministry of EducationCollege of Textile Science and EngineeringJiangnan UniversityWuxi214122China Institute of Textiles and Clothing The Hong Kong Polytechnic UniversityHung HomHong KongChina State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei230026China Jiangsu Key Laboratory of Hazardous Chemicals Safety and Control College of Safety Science and EngineeringNanjing Tech UniversityNanjing211816China Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefei230026China

Fabrication of flame retardants from renewable biomass has aroused extensive interest over the past *** work reported a synthesis of isosorbide-derived polyphosphonate(PICPP)as an anti-flammable agent for poly(lactic acid)(PLA).The presence of PICPP notably declined the storage modulus of PLA/PICPP owing to the declined molecular weight of PLA catalyzed by the presence of *** and PLA/PICPP thermally degraded in one stage under either air or nitrogen *** increasing the amount of PICPP,the onset thermal decomposition temperature of PLA/PICPP was decreased gradually,owing to the earlier decomposition of *** only 10 wt%of PICPP,PLA/PICPP-10 achieved a high limiting oxygen index of 30.0%and UL-94 V-0 classification,manifesting that PICPP was an efficient anti-flammable agent for *** inclusion of 15 wt%PICPP also caused 33%and 16%decline in PHRR and THR of PLA,***-IR results clarified that PLA/PICPP produced the less typical pyrolysis products especially flammable carbonyls than PLA,which may account for the suppressed PHRR and THR values of PLA/PICPP.

关键词： Isosorbide polyphosphonate poly(lactic acid) flame retardancy