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The Formation of Nano-Size SiO_2 Thin Film on an Aluminum Plate with Hexamethyldisilazane (HMDSA) and Hexamethyldisiloxane (HMDSO)

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Journal of Thermal Science 2003年第1期12卷 89-96页

作者： H.K.Ma E.Zhao K.M.chung c.l.yeh Dept of Mechanical Engineering National Taiwan UniversityDept of Mechanical Engineering National Taiwan UniversityDept of Mechanical Engineering National Taiwan UniversityDept of Mechanical Engineering Da-Yeh University 112 Taipei Taiwan 10764 China Taipei Taiwan 10764 ChinaTaipei Taiwan 10764 ChinaShan-Jeau Rd Dah-Tsuen Chang-Hwa Taiwan 51505 China

This study is using HMDSA (c6H19NSi2) or HMDSO (c6H18OSi2) vapor into c3H8/air premixed flames to form SiO2 thin film on the surface of an aluminum plate. With the addition of HMDSO or HMDSA to premixed flames, an orange secondary flame or a flame brush appeared and was contributed to the formation of Sio2 particles. Based upon the EDS, XPS and FTIR analysis, it is believed that the synthesized products consist of mainly SiO2 and a small amount of SiO. The pure SiO2 crystal structure, was proved by XRD analysis, which may form from the SiO2 amorphous structure after high temperature (1300c) thermal treatment. The nano-size SiO2 particles, which ranged from 2.5-25 nm, are proved by analysis of the BET and TEM. A 2-D cFD-Rc code with 12 reduced chemical reaction mechanism, based upon the SIMPlER procedure, was successfully employed to predict the flame temperature and both of the SiO2 and SiO concentration profiles. compared with the experimental results, the calculated temperature profiles in the post-flame region are in good agreement with the measured data and observation phenomena.

关键词： nano size thin film SiO2.

Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica l.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

APPlYING PROcESS MINING APPROAcH TO SUPPORT THE VERIFIcATION OF A MUlTI-AGENT SYSTEM

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Journal of Systems Science and Systems Engineering 2010年第2期19卷 131-149页

作者： c.OU-YANG yeh-chun JUAN Depart.of Industrial Management National Taiwan University of Science and Technology Depart.of Industrial Engineering and Management Ming Chi University of Technology

Using agent development tools to construct an agent-based system is a well applied approach. However, the development tools usually do not have the function to check the feasibility about the workflow of the agent system during it implementation stage. Therefore, to develop an evaluation approach to analyze the feasibility of a developing agent system such that the improper workflow of an agent system can be found in the early design stage is a necessary task to reduce the risk of implementation. In this research, a Petri Net （PN） based three-stage evaluation approach was developed. In the conceptual stage, the pitfall of the current agent system developing process was examined and an improvement analysis process was specified. Then, in the system design stage, an evaluation approach which extracted the process log file from a developing agent system into a PN model in terms of a process mining approach-or algorithm was proposed. This model was simulated in a PN simulation package. The agent system performance was evaluated in terms of analyzing the deadlock phenomena of the PN model. Finally, in the implementation stage, the proposed concept was implemented by using an agent developing tool JADE and a PN simulation tool cPN. An agent-based robotic assembly system was used to examine the possible deadlock of the agent system.

关键词： Agent-based systems workflow feasibility process mining Petri Nets

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： carina Hromada Patrick Heimel Markus Kerbl lászlóGál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes c.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller David Hercher Department life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian cluster for Tissue Regeneration ViennaAustria ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGcs). However, the use of tNGcs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGc would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGcs and compared the various features of these improved silk^(+) tNGcs with the tubes without holes(silk^(–) tNGcs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGcs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGcs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGcs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGcs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

Nanoscale strain engineering of graphene and graphene-based devices

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Acta Mechanica Sinica 2016年第3期32卷 497-509页

作者： N.-c.yeh c.-c.Hsu M.l.Teague J.-Q.Wang D.A.Boyd c.-c.chen Department of Physics Institute for Quantum Information and Matter and Kavli Nanoscience InstituteCalifornia Institute of Technology Department of Physics Fudan University Department of Physics California Institute of Technology

Structural distortions in nano-materials can induce dramatic changes in their electronic properties. This situation is well manifested in graphene, a two-dimensional honeycomb structure of carbon atoms with only one atomic layer thickness. In particular, strained graphene can result in both charging effects and pseudo-magnetic fields, so that controlled strain on a perfect graphene lattice can be tailored to yield desirable electronic properties. Here, we describe the theoretical foundation for strain-engineering of the electronic properties of graphene, and then provide experimental evidence for strain-induced pseudo-magnetic fields and charging effects in monolayer graphene. We further demonstrate the feasibility of nano-scale strain engineering for graphene-based devices by means of theoretical simulations and nano-fabrication technology.

关键词： Graphene Strain-engineering Nanostructures Dirac fermions Pseudo-magnetic field Valleytronics

Beginning from the end:the presynaptic terminal as a pathomechanism hub in frontotemporal dementia and amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第11期20卷 3217-3218页

作者： laura Huggon Emma l.clayton UK Dementia Research Institute at King’s college london LondonUK Department of Basic and clinical Neuroscience Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontotemporal dementia and amyotrophic lateral sclerosis:Frontotemporal dementia(F T D)and amyo t rophic lateral sclerosis(AlS)are neurodegenerative diseases with significant overlapping *** these neurodegenerative diseases affect different neuronal populations(with FTD affecting neurons of the frontal and temporal lobes,and AlS affecting upper and lower motor neurons),these two diseases are complexly *** and AlS exist on a disease spectrum,with shared genetic causes,clinical presentations,and pathologies.

关键词： diseases amyotrophic sclerosis

Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDlINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

Microstructural Evolution of Infrared Brazed cP-Ti Using Ti-cu-Ni Brazes

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Journal of Materials Science & Technology 2011年第2期27卷 131-138页

作者： c.T.chang T.Y.yeh R.K.Shiue c.S.chang Department of Mechanical Engineering National Hualien Industrial Vocational Senior High SchoolHualien 970TaiwanChina Department of Materials Science and Engineering National Taiwan UniversityTaipei 106TaiwanChina Engineered Materials Solutions 39 Perry AvenueMS 4-1AttleboroMA 02703-2410USA

Microstructural evolution of infrared vacuum brazed cP-Ti using two Ti-based braze alloys,Ti-15cu-15Ni and Ti-15cu-25Ni,has been *** infrared brazed joint consisted of eutectic Ti 2 cu/Ti 2 Ni intermetallic compounds and Ti-rich *** eutectic Ti 2 cu/Ti 2 Ni intermetallic compounds disappeared from the joint after being annealed at 900 c for 1 *** contrast,the depletion rate of both cu and Ni from the braze alloy into cP-Ti substrate at 750 c annealing was greatly decreased as compared with that annealed at 900 *** Ti 2 cu/Ti 2 Ni phases were observed even if the specimen was annealed at 750 c for 15 *** the Ni content of the Ti-15cu-25Ni braze alloy is much higher than that of the Ti-15cu-15Ni alloy,the amount of eutectic Ti 2 cu/Ti 2 Ni phases in Ti-15cu-25Ni brazed joint is more than that in Ti-15ci-15Ni brazed ***,similar microstructural evolution can be obtained from the infrared brazed joint annealed at various temperatures and/or time for both filler metals.

关键词： Infrared Brazing cP-Ti Ti-cu-Ni fillers Microstructure