检索结果-南通市图书馆

Data-driven Static Equivalence with Physics-informed Koopman Operators

在线全文

学校读者我要写书评

暂无评论

cSEE Journal of Power and Energy Systems 2024年第1期10卷 432-438页

作者： Wei lin changhong Zhao Maosheng Gao c.Y.chung Department of Electrical Engineering The Hong Kong Polytechnic UniversityHong Kong SARChina Department of Information Engineering The Chinese University of Hong KongHong Kong SARChina School of Electrical Engineering Chongqing UniversityChongqing 400044China

With deployment of measurement units,fitting static equivalent models of distribution networks(DNs)by linear regression has been recognized as an effective method in power flow analysis of a transmission network.Increasing volatility of measurements caused by variable distributed renewable energy sources makes it more difficult to accurately fit such equivalent models.To tackle this challenge,this letter proposes a novel data-driven method to improve equivalency accuracy of DNs with distributed energy resources.This letter provides a new perspective that an equivalent model can be regarded as a mapping from internal conditions and border voltages to border power injections.Such mapping can be established through 1)Koopman operator theory,and 2)physical features of power flow equations at the root node of a DN.Performance of the proposed method is demonstrated on the IEEE 33-bus and IEEE 136-bus test systems connected to a 661-bus utility system.

关键词： Data-driven distribution network Koopman operator theory static equivalent model

VOc emitted by biopharmaceutical industries:Source profiles,health risks,and secondary pollution

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第1期135卷 570-584页

作者： Jiawei Ma lin Li State Key Laboratory of Environmental Aquatic chemistry Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of chinese Academy of Sciences Beijing 100049China National Engineering Laboratory for VOcs Pollution control Material&Technology University of Chinese Academy of SciencesBeijing 101408China

The biopharmaceutical industry contributes substantially to volatile organic compounds(VOcs)emissions,causing growing concerns and social developmental conflicts.This study conducted an on-site investigation of the process-based emission of VOcs from three biopharmaceutical enterprises.In the workshops of the three enterprises,26 VOcs were detected,which could be sorted into 4 classes:hydrocarbons,aromatic hydrocarbons,oxygen-containing compounds,and nitrogen-containing compounds.Ketones were the main components of waste gases,accounting for 44.13%-77.85%of the overall VOcs.Process-based source profiles were compiled for each process unit,with the fermentation and extraction units of tiamulin fumarate being the main source of VOc emissions.Dimethyl heptanone,vinyl acetate,diethylamine,propylene glycol methyl ether(PGME),and benzene were screened as priority pollutants through a fuzzy comprehensive evaluation system.Ground level concentration simulation results of the Gauss plume diffusion model demonstrated that the diffusivity of VOcs in the atmosphere was relatively high,indicating potential non-carcinogenic and carcinogenic risks 1.5-2 km downwind.Furthermore,the process-based formation potentials of ozone and secondary organic aerosols(SOAs)were determined and indicated that N-methyl-2-pyrrolidone,dimethyl heptanone,and PGME should be preferentially controlled to reduce the ozone formation potential,whereas the control of benzene and chlorobenzene should be prioritized to reduce the generation of SOAs.Our results provide a basis for understanding the characteristics of VOc emission by biopharmaceutical industries and their diffusion,potentially allowing the development of measures to reduce health risks and secondary pollution.

关键词： Biopharmaceutical Volatile organic compound Priority pollutant Exposure risk Secondary pollution

construction of algal-bacterial consortia using green microalgae chlorella vulgaris and As(Ⅲ)-oxidizing bacteria:As tolerance and metabolomic profiling

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第5期139卷 258-266页

作者： Xiaoman He Guobing lin Jiayuan Zeng Zhaoguang Yang lin Wang college of chemistry and chemical Engineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety Central South UniversityChangsha 410083China

Bioremediation became a promising technology to resolve arsenic(As)contamination in aquatic environment.Since monoculture such as microalgae or bacteria was sensitive to environmental disturbance and vulnerable to contamination,green microalgae chlorella vulgaris and arsenite(As(Ⅲ))-oxidizing bacteria Pseudomonas sp.SMS11 were co-cultured to construct algal-bacterial consortia in the current study.The effects of algae-bacteria(A:B)ratio and exposure As(Ⅲ)concentration on algal growth,As speciation and metabolomic profile were investigated.Algal growth arrested when treated with 100 mg/L As(Ⅲ)without the co-cultured bacteria.By contrast,co-cultured with strain SMS11 significantly enhanced As tolerance in c.vulgaris especially with A:B ratio of 1:10.All the As(Ⅲ)in culture media of the consortia were oxidized into As(Ⅴ)on day 7.Methylation of As was observed on day 14.Over 1% and 0.5% of total As were converted into dimethylarsinic acid(DMA)after 21days cultivation when the initial concentrations of As(Ⅲ)were 1 and 10 mg/L,respectively.Metabolomic analysis was further performed to reveal the response of consortia metabolites to external As(Ⅲ).The enriched metabolomic pathways were associated with carbohydrate,amino acid and energy metabolisms.Tricarboxylic acid cycle and glyoxylate and dicarboxylate metabolism were upregulated under As stress due to their biological functions on alleviating oxidative stress and protecting cells.Both carbohydrate and amino acid metabolisms provided precursors and potential substrates for energy production and cell protection under abiotic stress.Alterations of the pathways relevant to carbohydrate or amino acid metabolism were triggered by energy requirement.

关键词： Microalgae Algal-bacterial consortia As(Ⅲ)-oxidizing bacteria Metabolomics Energy metabolism

A fast forward computational method for nuclear measurement using volumetric detection constraints

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第2期35卷 47-63页

作者： Qiong Zhang lin-Lv lin University of Electronic Science and Technology of china Chengdu 610000China

Owing to the complex lithology of unconventional reservoirs,field interpreters usually need to provide a basis for interpretation using logging simulation models.Among the various detection tools that use nuclear sources,the detector response can reflect various types of information of the medium.The Monte carlo method is one of the primary methods used to obtain nuclear detection responses in complex environments.However,this requires a computational process with extensive random sampling,consumes considerable resources,and does not provide real-time response results.Therefore,a novel fast forward computational method(FFcM)for nuclear measurement that uses volumetric detection constraints to rapidly calculate the detector response in various complex environments is proposed.First,the data library required for the FFcM is built by collecting the detection volume,detector counts,and flux sensitivity functions through a Monte carlo simulation.Then,based on perturbation theory and the Rytov approximation,a model for the detector response is derived using the flux sensitivity function method and a one-group diffusion model.The environmental perturbation is constrained to optimize the model according to the tool structure and the impact of the formation and borehole within the effective detection volume.Finally,the method is applied to a neutron porosity tool for verification.In various complex simulation environments,the maximum relative error between the calculated porosity results of Monte carlo and FFcM was 6.80%,with a rootmean-square error of 0.62 p.u.In field well applications,the formation porosity model obtained using FFcM was in good agreement with the model obtained by interpreters,which demonstrates the validity and accuracy of the proposed method.

关键词： Nuclear measurement Fast forward computation Volumetric constraints

The physiological role of the unfolded protein response in the nervous system

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第11期19卷 2411-2420页

作者： Shuangchan Wu Wensheng lin Department of Neuroscience University of MinnesotaMinneapolisMNUSA Institute for Translational Neuroscience University of MinnesotaMinneapolisMNUSA

The unfolded protein response(UPR)is a cellular stress response pathway activated when the endoplasmic reticulum,a crucial organelle for protein folding and modification,encounters an accumulation of unfolded or misfolded proteins.The UPR aims to restore endoplasmic reticulum homeostasis by enhancing protein folding capacity,reducing protein biosynthesis,and promoting protein degradation.It also plays a pivotal role in coordinating signaling cascades to determine cell fate and function in response to endoplasmic reticulum stress.Recent research has highlighted the significance of the UPR not only in maintaining endoplasmic reticulum homeostasis but also in influencing various physiological processes in the nervous system.Here,we provide an overview of recent findings that underscore the UPR’s involvement in preserving the function and viability of neuronal and myelinating cells under physiological conditions,and highlight the critical role of the UPR in brain development,memory storage,retinal cone development,myelination,and maintenance of myelin thickness.

关键词： myelin neuron oligodendrocyte Schwann cell unfolded protein response

NFXL1 functions as a transcriptional activator required for thermotolerance at reproductive stage in Arabidopsis

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2024年第1期66卷 54-65页

作者： Qiao‐Yun Zhu lin‐lin Zhang Jian‐Xiang Liu State Key Laboratory of Plant Environmental Resilience College of Life SciencesZhejiang UniversityHangzhou 310027China

Plants are highly susceptible to abiotic stresses,particularly heat stress during the reproductive stage.However,the specific molecular mechanisms underlying this sensitivity remain largely unknown.In the current study,we demonstrate that the Nuclear Transcription Factor,X-box Binding Protein 1-Like 1(NFXL1),directly regulates the expression of DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 2A(DREB2A),which is crucial for reproductive thermotolerance in Arabidopsis.NFXL1 is upregulated by heat stress,and its mutation leads to a reduction in silique length(seed number)under heat stress conditions.RNA-Seq analysis reveals that NFXL1 has a global impact on the expression of heat stress responsive genes,including DREB2A,Heat Shock Factor A3(HSFA3)and Heat Shock Protein 17.6(HSP17.6)in flower buds.Interestingly,NFXL1 is enriched in the promoter region of DREB2A,but not of either HSFA3 or HSP17.6.Further experiments using electrophoretic mobility shift assay have confirmed that NFXL1 directly binds to the DNA fragment derived from the DREB2A promoter.Moreover,effector-reporter assays have shown that NFXL1 activates the DREB2A promoter.The DREB2A mutants are also heat stress sensitive at the reproductive stage,and DEREB2A is epistatic to NFXL1 in regulating thermotolerance in flower buds.It is known that HSFA3,a direct target of DREB2A,regulates the expression of heat shock proteins genes under heat stress conditions.Thus,our findings establish NFXL1 as a critical upstream regulator of DREB2A in the transcriptional cassette responsible for heat stress responses required for reproductive thermotolerance in Arabidopsis.

关键词： Arabidopsis DREB2A heat stress NFXL1 reproductive thermotolerance

Emerging role of lncRNAs as mechanical signaling molecules in mechanotransduction and their association with Hippo-YAP signaling:a review

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第4期25卷 280-292页

作者： Siyi lin Xinyu HE Ying WANG Yu cHEN Aifu lin college of Medicine Zhejiang UniversityHangzhou 310058China college of Life Sciences Zhejiang UniversityHangzhou 310058China cancer center Zhejiang UniversityHangzhou 310058China Key Laboratory for cell and Gene Engineering of Zhejiang Province Hangzhou 310058China International School of Medicine International Institutes of Medicinethe Fourth Affiliated Hospital of Zhejiang University School of MedicineYiwu 322000China Key Laboratory of cancer Prevention and Intervention China National Ministry of EducationHangzhou 310058China Future Health Laboratory Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100China

cells within tissues are subject to various mechanical forces,including hydrostatic pressure,shear stress,compression,and tension.These mechanical stimuli can be converted into biochemical signals through mechanoreceptors or cytoskeleton-dependent response processes,shaping the microenvironment and maintaining cellular physiological balance.Several studies have demonstrated the roles of Yes-associated protein(YAP)and its homolog transcriptional coactivator with PDZ-binding motif(TAZ)as mechanotransducers,exerting dynamic influence on cellular phenotypes including differentiation and disease pathogenesis.This regulatory function entails the involvement of the cytoskeleton,nucleoskeleton,integrin,focal adhesions(FAs),and the integration of multiple signaling pathways,including extracellular signal-regulated kinase(ERK),wingless/integrated(WNT),and Hippo signaling.Furthermore,emerging evidence substantiates the implication of long non-coding RNAs(lncRNAs)as mechanosensitive molecules in cellular mechanotransduction.In this review,we discuss the mechanisms through which YAP/TAZ and lncRNAs serve as effectors in responding to mechanical stimuli.Additionally,we summarize and elaborate on the crucial signal molecules involved in mechanotransduction.

关键词： YAP/TAZ Long non-coding RNA(lncRNA) Mechanotransduction F-actin

Microwave dielectric properties of cacu_(3)Ti_(4)O_(12) ceramics:A clue to its intrinsic dielectric response

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Dielectrics 2023年第5期13卷 20-25页

作者： X.Huang H.X.Guo P.S.Zhu L.Liu J.Xiao D.P.Tang c.lin X.Wu X.H.Zheng Institute of Advanced ceramics College of Materials Science and Engineering Fuzhou University2 Xueyuan RoadUniversity TownFuzhou 350108P.R.China School of Mechanical and Automotive Engineering Fujian University of Technology 3 Xueyuan RoadUniversity TownFuzhou 350118P.R.China college of Zijin Mining Fuzhou University2 Xueyuan Road University TownFuzhou 350108P.R.China

cacu_(3)Ti_(4)O_(12)(ccTO)is a potential dielectric material with giant permittivity,good stability over the wide temperature and frequency range.However,the dielectric responses of ccTO-based ceramics are mainly investigated in the frequency of 102-106 Hz,which is far low to clarify the intrinsic dielectric feature.So,microwave dielectric properties have been investigated for the ccTO porous ceramics sintered at low temperature(≤1000°c).Good microwave dielectric properties of permittivityε=62.7,quality factor Qf=3062 GHz and temperature coefficient of the resonant frequencyτf=179 ppm/°c are achieved for the ccTO ceramics sintered at 1000°c,the dielectric loss significantly decreases two orders to 0.002 compared to that of ccTO ceramics sintered at critical temperature of 1020°c confirmed by differential scanning calorimetry(DSc).This clue indicates that giant permittivity and high loss is not intrinsic for ccTO ceramics,but derives from composition segregation,liquid phase and defects associated with internal barrier layer capacitor(IBLc).It suggests that ccTO-based ceramics is a promising microwave dielectric materials with high permittivity.

关键词： ccTO microwave dielectric properties sintering temperature dielectric mechanism

comprehensive study on the spatial distribution of heavy metals and their environmental risks in high-sulfur coal gangue dumps in china

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第2期136卷 486-497页

作者： Yingbo Dong Huan Lu Hai lin School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory on Resource-oriented Treatment of Industrial Pollutants Beijing 100083China

The accumulation of coal gangue(cG)from coal mining is an important source of heavy metals(HMs)in soil.Its spatial distribution and environment risk assessment are extremely important for the management and remediation of HMs.Eighty soil samples were collected from the high-sulfur cG site in northern china and analyzed for six HMs.The results showed that the soil was heavily contaminated by Mn,cr and Ni based on the Nemerow index,and posed seriously ecological risk depended on the geo-accumulation index,potential ecological risk index and risk assessment code.The semi-variogram model and ordinary kriging interpolation accurately portrayed the spatial distribution of HMs.Fe,Mn,and cr were distributed by band diffusion,Ni was distributed by core,the distribution of cu had obvious patchiness and Zn was more uniform.The spatial autocorrelation indicated that all HMs had strong spatial heterogeneity.The BcR sequential extraction was employed to qualify the geochemical fractions of HMs.The data indicated that Fe and cr were dominated by residual fraction;cu,Ni and Zn were dominated by reducible and oxidizable fractions;Mn was dominated by reducible and acid-extractable(25.38%-44.67%)fractions.Pearson correlation analysis showed that pH was the main control factor affecting the non-residue fractions of HMs.Therefore,acid production from high sulfur cG reduced soil pH by 2-3,which indirectly promoted the activity of HMs.Finally,the conceptual model of HMs contamination at the cG site was proposed,which can be useful for the development of ecological remediation strategies.

关键词： High-sulfur coal gangue Soil contamination Heavy metals Spatial distribution Geochemical fractions Risk assessment