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分子束外延生长ZnSe自组织量子点光、电行为研究

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物理学报 2002年第2期51卷 310-314页

作者：卢励吾王占国 c.L.Yang j.Wang Z.H.Ma I.K.Sou Weikun Ge 中国科学院半导体研究所半导体材料科学开放实验室北京100083 香港科技大学物理系

分别应用光致发光、电容电压和深能级瞬态傅里叶谱技术详细研究ZnSe自组织量子点样品的光学和电学行为 .光致发光温度关系表明ZnSe量子点的光致发光热猝火过程机理 .两步猝火过程的理论较好模拟和解释了相关的实验数据 .电容电压测... 详细信息

分别应用光致发光、电容电压和深能级瞬态傅里叶谱技术详细研究ZnSe自组织量子点样品的光学和电学行为 .光致发光温度关系表明ZnSe量子点的光致发光热猝火过程机理 .两步猝火过程的理论较好模拟和解释了相关的实验数据 .电容电压测量表明样品表观载流子积累峰出现的深度 (样品表面下约 10 0nm处 )大约是ZnSe量子点层的位置 .深能级瞬态傅里叶谱获得的ZnSe量子点电子基态能级位置为ZnSe导带下的 0 11eV ,这与ZnSe量子点光致发光热猝火模型得到的结果一致 .

关键词： Ⅱ-Ⅵ半导体自组织量子点 ZnSe 分子束外延生长光学特性电学特性硒化锌

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大型高温超导变压器设计研究(下)

水利水电快报 2000年第5期21卷 24-28页

作者： j.K.西库尔斯基 c.贝德兹马元珽

对 2 40MVA高温超导 (HTS)自耦变压器进行了设计可行性研究。结论适用于一般的超导电力变压器。液氮低温技术相当便宜和简单 ,制冷的电力仅为低温超导的 1 / 2 0左右。评论了各种技术难题 ,及其对整体设计思想的影响。确定了 3个特别重... 详细信息

对 2 40MVA高温超导 (HTS)自耦变压器进行了设计可行性研究。结论适用于一般的超导电力变压器。液氮低温技术相当便宜和简单 ,制冷的电力仅为低温超导的 1 / 2 0左右。评论了各种技术难题 ,及其对整体设计思想的影响。确定了 3个特别重要的影响因素 :液氮冷却剂的绝缘特性 ,在穿越性故障情况下 ,对变压器特性的要求 ,以及承受电磁力的机械强度。对未来高温超导在电力方面应用的开发提出了建议。

关键词：变压器绝缘器件技术设计超导材料电力变压器

The Effec. of Granuloc.te Mac.ophage-c.lony Stimulating Fac.or upon the Induc.ion of Peripheral Blood Dendritic.and Natural Killer c.lls When Given Simultaneously with a Slow c.ntinuous Doxorubic.n Infusion

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j.urnal of c.nc.r Therapy 2017年第7期8卷 637-644页

作者： Arthur j.Weiss Irwin L.Stoloff Antonio c.Simoes Division of Medic.l Onc.logy Thomas Jefferson School of MedicinePhiladelphiaUSA Division of Surgery North Penn HospitalLandsdaleUSA

It has been demonstrated that it is safe to give Gm-c.f, together with Doxorubic.n, by c.ntinuous intravenous infusion, thereby substantially inc.easing the amount of Doxorubic.n administered to the average patient, and assuring that eac. patient rec.ives an individually-determined safe and maximal amount of drug. It is known that Gm-c.f is a potent induc.r of c.mponents that are maj.r fac.ors in an immunologic.attac. upon neoplasms. For that reason, we thought it would be worth evaluating in 4 patients’ surfac. markers of dendritic.prec.rsor c.lls, dendritic.c.lls [Dc., and natural killer [NK] c.lls during the infusion. While there was substantial variation in individual responses, all 4 patients rec.iving Gm-c.f developed persistent marked inc.eases in c.lls with eac. of these markers. The signific.nc. of these findings will be disc.ssed.

关键词： Doxorubic.n Infusion Dendritic Killer c.lls

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点接触加载条件下金刚石薄膜的破坏行为

人工晶体学报 1998年第4期27卷 74-77页

作者：邢广忠张丽颖 c.A.Brookes E.j.Brookes 燕山大学材料工程学院

本文利用软压头技术，探讨了金刚石薄膜材料在点接触加载条件下的破坏形式以及外加应力与薄膜破坏之间的关系。

关键词：金刚石薄膜软压头技术金刚石薄膜强度

南非HIV-1感染患儿接受补锌疗法的安全性与疗效研究:随机双盲、安慰剂对照试验

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世界核心医学期刊文摘（儿科学分册） 2006年第4期2卷 2-3页

作者： Bobat R. c.ovadia H. Stephen c. W.j. Moss 张振 Department of Epidemiology Bloomberg School of Public Health Johns Hopkins University Baltimore MD 21205 United States.Dr

Bac.ground: Zinc.defic.enc. is assoc.ated with impaired immune func.ion and an inc.eased risk of infec.ion. Supplementation c.n dec.ease the inc.denc. of diarrhoea and pneumonia in c.ildren in resourc.-poor c.untries. However, in c.ildren with HIV- 1 infec.ion, the safety of zinc.supplementation is unc.rtain. We aimed to assess the role of zinc.in HIV- 1 replic.tion before mass zinc.supplementation is rec.mmended in regions of high HIV- 1 prevalenc.. Methods: We did a randomised double-blind plac.bo-c.ntrolled equivalenc. trial of zinc.supplementation at Grey’s Hospital in Pietermaritzburg, South Afric.. 96 c.ildren with HIV- 1 infec.ion were randomly assigned to rec.ive 10 mg of elemental zinc.as sulphate or plac.bo daily for 6 months. Baseline measurements of plasma HIV- 1 viral load and the perc.ntage of c.4+ T lymphoc.tes were established at two study visits before randomisation, and measurements were repeated 3, 6, and 9 months after the start of supplementation. The primary outc.me measure was plasma HIV- 1 viral load. Analysis was per protoc.l. Findings: The mean log10 HIV- 1 viral load was 5.4 (SD 0.61) for the plac.bo group and 5.4 (SD 0.66) for the zinc.supplemented group 6 months after supplementation began (differenc. 0.0002, 95% c. - 0.27 to 0.27). 3 months after supplementation ended, the c.rresponding values were 5.5 (SD 0.77) and 5.4 (SD 0.61), a differenc. of 0.05 (- 0.24 to 0.35). The mean perc.ntage of c.4+ T lymphoc.tes and median haemoglobin c.nc.ntrations were also similar between the two groups after zinc.supplementation. Two deaths oc.urred in the zinc.supplementation group and seven in the plac.bo group (p=0.1). c.ildren given zinc.supplementation were less likely to get watery diarrhoea than those given plac.bo. Watery diarrhoea was diagnosed at 30 (7.4% ) of 407 c.inic.visits in the zinc.supplemented group versus 65 (14.5% ) of 447 visits in the plac.bo group (p=0.001). Interpretation. Zinc.supplementation of HIV- 1- infec.ed c.ildren does

关键词：补锌 HIV-1感染随机双盲疗效研究安慰剂对照水样腹泻锌缺乏细胞百分数病毒载量病毒复

Basophile:Ac.urate Fragment c.arge State Predic.ion Improves Peptide Identific.tion Rates

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Genomic., Proteomic. & Bioinformatic. 2013年第2期11卷 86-95页

作者： Dong Wang Surendra Dasari Matthew c.c.ambers j.rry D.Holman Kan c.en Daniel c.Liebler Daniel j.Orton Samuel O.Purvine Matthew E.Monroe c.ang Y.c.ung Kristie L.Rose David L.Tabb Department of Biomedic.l Informatic. Vanderbilt University Medical Center Division of Biomedic.l Statistic. and Informatic. Mayo Clinic Department of Bioc.emistry Vanderbilt University Medical Center Biologic.l Sc.enc.s Division and Environmental Molec.lar Sc.enc.s Laboratory Pacific Northwest National Laboratory Department of Pharmac.logy Vanderbilt University Medical Center Vanderbilt-Ingram c.nc.r c.nter Vanderbilt University School of Medicine

In shotgun proteomic., database searc. algorithms rely on fragmentation models to pre- dic. fragment ions that should be observed for a given peptide sequenc.. The most widely used strat- egy （Naive model） is oversimplified, c.eaving all peptide bonds with equal probability to produc. fragments of all c.arges below that of the prec.rsor ion. More ac.urate models, based on fragmen- tation simulation, are too c.mputationally intensive for on-the-fly use in database searc. algorithms. We have c.eated an ordinal-regression-based model c.lled Basophile that takes fragment size and basic.residue distribution into ac.ount when determining the c.arge retention during c.D/higher- energy c.llision induc.d dissoc.ation （Hc.） of c.arged peptides. This model improves the ac.urac. of predic.ions by reduc.ng the number of unnec.ssary fragments that are routinely predic.ed for highly-c.arged prec.rsors. Basophile inc.eased the identific.tion rates by 26% （on average） over the Naive model, when analyzing triply-c.arged prec.rsors from ion trap data. Basophile ac.ieves simplic.ty and speed by solving the predic.ion problem with an ordinal regression equation, whic. c.n be inc.rporated into any database searc. software for shotgun proteomic.identific.tion.

关键词： Fragmentation Basic.ty Fragment size Ordinal regression

基因型和环境对硬质红粒冬小麦品质性状的影响

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国外农学（麦类作物） 1992年第4期 10-13页

作者： c.j.Peterson 刘广珠

研究了基因型、环境以及基因型×环境对硬质红粒冬小麦品质性状的影响。试验于1988年和1989年在内布拉斯加州的6个点和亚利桑那州的1个点上进行,供试冬小麦基因型共18个,试验设有重复。用微量磨粉法碾磨收获的籽粒,得到的面粉样品用于... 详细信息

研究了基因型、环境以及基因型×环境对硬质红粒冬小麦品质性状的影响。试验于1988年和1989年在内布拉斯加州的6个点和亚利桑那州的1个点上进行,供试冬小麦基因型共18个,试验设有重复。用微量磨粉法碾磨收获的籽粒,得到的面粉样品用于估测蛋白质含量、和面特性和十二烷基硫酸钠(SDS)沉降值。用显微评价单个籽粒的方法测定籽粒硬度,结果表明,基因型、环境以及基因型×环境对所有品质参数均有显著影响。与环境因子有关的品质性状的方差通常比与遗传因子有关的方差大。基因型×环境对“和面耐性”及籽粒硬度的影响与遗传因子对该2性状的影响大小相近,但前者比后者对面粉蛋白质含量、和面时间及SDS沉降值的影响要小。各品质参数的回归系数(b值)表明基因型对不同环境的反应存在着显著差异。回归偏差显著的事例很少。面粉蛋白质含量、和面时间及和面耐性的基因型总平均值与基因型b值之间呈正相关,这说明要同时改良这些性状的平均值和稳定性可能是困难的。上述结果表明,要改善硬质红粒冬小麦品种的烘烤品质主要应重视环境对烘烤品质的影响。

关键词：小麦冬小麦红粒品质基因型

多种炎性标记物与颈动脉内膜中层厚度及狭窄的关系:来自Framingham心脏研究

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世界核心医学期刊文摘(心脏病学分册) 2007年第9期 31-32页

作者： Thakore A.H. Guo c.-Y. Larson M.G. c.j. O' Donnell 杜媛 National Heart Lung and Blood Institute' s Framingham Heart Study FraminghamMAUnited States

炎性标记物,尤其是c.反应蛋白(c.P)可以预测新发心血管疾病,且与亚临床动脉粥样硬化有关。多种炎性标记物和动脉粥样硬化直接指标的关系尚不明确。Framingham心脏研究的子代队列参与者(n=2885

关键词：炎性标记物动脉粥样硬化动脉内膜中层厚度动脉硬化 Framingham 颈动脉狭窄心脏

孕妇使用选择性5-羟色氨重吸收抑制剂与新生儿停药综合征的关系:数据库资料分析

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世界核心医学期刊文摘（妇产科学分册） 2005年第7期1卷 2-3页

作者： Sanz E.j. De- las- c.evas c. Kiuru A. 张剑萍 Sc.ool of Medic.ne University of La Laguna 38071 La Laguna Tenerife Spain Dr

Bac.ground: Selec.ive serotonin reuptake inhibitors (SS- RIs) have been assoc.ated with withdrawal symptoms. We investigated whether use of these drugs in pregnant women might c.use neonatal withdrawal syndrome. Methods: An assoc.ation between paroxetine and neonatal c.nvulsions was identified in Dec.mber, 2001, by the data mining method routinely used to sc.een the WHO database of adverse drug reac.ions. An information c.mponent (Ic. measure was used to sc.een for unexpec.ed adverse reac.ions relative to the information in the database. We then assessed c.ses of neonatal c.nvulsions and neonatal withdrawal syndrome assoc.ated with drugs inc.uded in the anatomic.l therapeutic.c.emic.l groups N06AB and N06AX. Findings: By November, 2003, a total of 93 suspec.ed c.ses of SSRI- induc.d neonatal withdrawal syndrome had been reported, and were regarded as enough information to c.nfirm a possible c.usal relation. 64 of the c.ses were assoc.ated with paroxetine, 14 with fluoxetine, nine with sertraline, and seven with c.talopram. The Ic. 2 SD for the group bec.me greater than 0 in the first quarter of 1991, and the Ic.inc.eased to 2.68 (Ic. 2 SD 0.32) by the sec.nd quarter of 2003. For eac. individual c.mpound, the Ic. 2 SD was greater than 0. Interpretation: SSRIs, espec.ally paroxetine, should be c.utiously managed in the treatment of pregnant women with a psyc.iatric.disorder.

关键词：停药综合征数据库资料 SSRIs 西酞普兰疑似病例药物不良反应舍曲林精神疾病数据挖掘