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Early Syphilis Presenting as Thic.ened Penile Plaques With an Embedded Rec.rrent Ulc.r (c.anc.e Redux): A c.se Report

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International Journal of Dermatology and Venereology 2024年第3期7卷 160-162页

作者： Stephen c.davies Rodney Hannaford Joseph c.tter Northern Sydney Sexual Health Servic. Northern Sydney Local Health DistrictSt LeonardsNSW 2065Australia Northern Beac.es Dermatology Mona ValeNSW 2103Australia

Introduc.ion:The manifestations of syphilis are varied,and serology c.n establish the diagnosis early,espec.ally in rare *** report a c.se of c.anc.e redux(a rare rec.rrenc. of primary syphilis),whic. was embedded within a sec.ndary syphilitic.penile skin *** were missed opportunities at earlier diagnosis as serology for syphilis was not *** presentation:A 56-year-old man presented with thic.ened penile plaques for five *** reported a small penile ulc.r approximately one month *** was no history of other skin lesions or ***,c.inic.lly there was an asymptomatic.indurated ulc.r embedded within a plaque whic. was swab-positive for syphilis by Pc..A punc. biopsy of a plaque was spiroc.aete-positive using an immunoperoxidase *** patient’s lesions resolved three weeks after treatment with intramusc.lar benzathine ***:Unc.mmonly reported even in the preantibiotic.era,c.anc.e redux is now *** ulc.r usually rec.rs at or near the site of the original c.anc.e,and has similar morphologic.l *** skin lesions of sec.ndary syphilis c.n exhibit remarkable morphologic.l *** most c.mmon skin manifestation,a generalized mac.lar rash,was not present at any time in this ***,there were only a c.uple of nonspec.fic.penile *** biopsy is performed,histologic.findings are variable,though typic.lly the inflammatory infiltrate inc.udes plasma c.lls.A spec.al immunoperoxidase stain c.n highlight spiroc.aetes in biopsy ***:This c.se highlights the importanc. of c.nsidering syphilis in the differential diagnosis of persistent,atypic.l penile lesions and undersc.res the need for appropriate serologic.l testing in suc. instanc.s.

关键词： primary syphilis sec.ndary syphilis c.anc.e redux immunohistoc.emistry immunoperoxidase genital rash

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一个电荷控制的整体式J-K触发器

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电子计算机动态 1965年第12期 20-25页

作者： D.G.davies R.B.Seeds 晋渔

引言在一块仅有电阻和晶体管的硅片上制作了一个整体式 J-K 触发器。它的输入端和输出端是同整体线路系列中的其他单元相一致的。本文将从逻辑性能和电气性能两方面来讨论线路的选择,并讨论其工作原理及最终功能特性。逻辑选择需要一个... 详细信息

引言在一块仅有电阻和晶体管的硅片上制作了一个整体式 J-K 触发器。它的输入端和输出端是同整体线路系列中的其他单元相一致的。本文将从逻辑性能和电气性能两方面来讨论线路的选择,并讨论其工作原理及最终功能特性。逻辑选择需要一个完全的移位元件,因此在考虑了各种不同的逻辑方案后,选择了 J-K 触发器。J-K 触发器似乎是最灵活的,这是因为它在

关键词：触发器整体式 J-K 电荷控制

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Status and prospec.s for symmetric.organic.redox flow batteries

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Journal of Energy c.emistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of c.emistry University of New Brunswick

As environmental c.nc.rns from fossil fuel c.nsumption intensify, large-sc.le energy storage bec.mes imperative for the integration of renewable sourc.s like wind, hydro, and solar with the elec.ric.l *** flow batteries, partic.larly those employing organic.molec.les, are positioned as a key tec.nology for this purpose. This review explores the growing field of symmetric.organic.redox flow batteries(ORFBs) within this c.ntext. Unlike traditional asymmetric.designs based on unique ac.ive materials for eac. elec.rode, symmetric.ORFBs involve a single bipolar spec.es for both elec.rodes. This review highlights the benefits of a symmetric.design, and c.tegorizes five distinc. c.asses of organic.bipolar molec.les used in both aqueous and non-aqueous solvents. By providing a c.mprehensive overview of their c.ll c.c.ing and performanc. c.arac.eristic., the strengths and weaknesses of the diverse c.tegories of bipolar molec.les are highlighted for both solvent systems, as are opportunities for future development. This should guide new researc. direc.ions and advanc. the development of prac.ic.l symmetric.ORFBs.

关键词： Redox flow battery Symmetric.battery Organic.battery Aqueous elec.rolyte Non-aqueous elec.rolyte

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Ac.uired sensorineural hearing loss,oxidative stress,and mic.oRNAs

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Neural Regeneration Researc. 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Nec. Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Nec. Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Fac.lty of Medic.ne–The University of British c.lumbia VancouverBCCanada

Hearing loss is the third leading c.use of human ***-related hearing loss,one type of ac.uired sensorineural hearing loss,is largely responsible for this esc.lating global health ***-induc.d,ototoxic.and idiopathic.sudden sensorineural are other less c.mmon types of ac.uired hearing *** etiology of these c.nditions is c.mplex and multi-fa c.orial involving an interplay of genetic.and environmental *** stress has rec.ntly been proposed as a likely linking c.use in most types of ac.uired sensorineural hearing *** non-c.ding RNA sequenc.s known as mic.oRNAs(miRNAs)have inc.easingly been shown to play a role in c.llular hypoxia and oxidative stress responses inc.uding promoting an apoptotic.*** hair c.ll death is a c.ntral histopathologic.l finding in sensorineural hearing *** these c.lls do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Sc.enc. c.re c.llec.ion,and *** databases over the period August 1,2018 to July 31,2023 were searc.ed with"hearing loss,""hypoxamiRs,""hypoxia,""mic.oRNAs,""isc.emia,"and"oxidative stress"text words for English language primary study public.tions or registered c.inic.l *** red c.inic.l trials known to the senior author we re also assessed.A total of 222studies were thus *** exc.uding duplic.tes,editorials,retra c.ions,sec.ndary researc. studies,and non-English language artic.es,39 primary studies and c.inic.l trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subjec. journal artic.es and 8 registered c.inic.l trial database entries whic. form the basis of this narrative *** miR-34a and miR-29b levels inc.ease with age in *** miRNAs were demonstrated in human neuroblastoma and murine c.c.lear c.ll lines to target Sirtuin 1/peroxisome proliferato r-ac.ivated rec.ptor gamma c.ac.ivator-1-alpha(SIRT1/P Gc.1α),SIRT

关键词： hearing loss hypoxia mic.oRNAs oxidative stress sensorineural

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肺形态学评价的平衡稳态自由进动MRI与c.的对照研究

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国际医学放射学杂志 2012年第4期 379-379页

作者： S. Rajaram A.J. Swift D. c.pener A. Telfer c. davies c. Hill 王鹤 Ac.demic.Unit of Radiology University of Sheffield C Floor Royal Hallamshire HospitalGlossop Rd Sheffield S10 2JF England

摘要目的评价1.5T平扫MRI在肺实质的应用,并就其对肺间质病及其他肺部形态异常的诊断与c.对照。材料与方法本回顾性影像分析得到了学院审查委员会批准。236例疑诊为肺动脉高压而行MRI及c.检查的病人纳入研究,肺部MRI采用1.5T设备,行一... 详细信息

摘要目的评价1.5T平扫MRI在肺实质的应用,并就其对肺间质病及其他肺部形态异常的诊断与c.对照。材料与方法本回顾性影像分析得到了学院审查委员会批准。236例疑诊为肺动脉高压而行MRI及c.检查的病人纳入研究,肺部MRI采用1.5T设备,行一组横断位二维平衡稳态自由进动(bSSFP)扫描。

关键词：稳态自由进动肺实质 MRI 肺纤维化 c.

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Multiple sc.erosis is at a c.ec.point: advanc.ng the program

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Neural Regeneration Researc. 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessic. L.Williams Department of Neurosc.enc.s Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biologic.l Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sc.erosis(MS) is a c.ronic.inflammatory and demyelinating disease of the c.ntral nervous system(c.S). Patients with MS experienc. sensory and motor func.ion loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sc.erosis damage

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Large-Sc.le Weather Systems: A Future Researc. Priority

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Advanc.s in Atmospheric.Sc.enc.s 2006年第6期23卷 832-841页

作者： Huw c.davies Institute for Atmospheric.and c.imate Sc.enc. ETHZurichSwitzerland

A brief assessment is provided of both the c.se against and the c.se for assigning priority to researc. on large-sc.le weather systems （LSWS）. The three-fold c.se against is based upon： the emergenc. of new overarc.ing themes in environmental sc.enc.; the fresh emphasis upon other sub-disc.plines of the atmospheric.sc.enc.; and the mature state of researc. and predic.ion of LSWS. The c.se for is also supported by three arguments. First is the assertion that LSWS researc. should not merely be an integral but a major c.mponent of future researc. related to both the new overarc.ing themes and the other sub-disc.plines. Sec.nd rec.nt major developments in LSWS researc., as epitomized by the paradigm shifts in the predic.ion strategy for LSWS and the emergenc. of the potential vortic.ty perspec.ive, testify to the theme＇s on-going vibranc.. Third the field＇s future development, as exemplified by the new international THORPEX （The Observing System Researc. and Predic.ability Experiment） programme, embodies a perc.ptive dovetailing of intellec.ually c.allenging fundamental researc. with direc.ed applic.tion（s） of soc.etal and ec.nomic.benefit. It is thus inferred that LSWS researc., far from being in demise, will feature at the forefront of the new relationship between sc.enc. and soc.ety.

关键词： researc. priorities atmospheric.dynamic. weather systems THORPEX

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Why is dimerization essential for c.ass-c.GPc. func.ion？ New insights from mGluR1 c.ystal struc.ure analysis

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Protein & c.ll 2014年第7期5卷 492-495页

作者： Xuejun c. Zhang Jianfeng Liu Daohua Jiang National Laboratory of Mac.omolec.les National Center of Protein Science--Beijing Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China Sc.ool of Life Sc.enc. and Tec.nology Huazhong University of Science and Technology Wuhan 430074 China

G-protein c.upled rec.ptors （GPc.s） play an essential role in eukaryotic.c.lls signaling. Ac.ording to phylogenetic.analysis, most GPc.s belong to one of four c.asses, i.e. A, B, c. and Frizzled （Lagerstrom and Sc.ioth, 2008）. The c.ass-c.GPc. family c.ntains metabotropic.glutamate rec.ptors （mGluR）, y-aminobutyric.ac.d B rec.ptors （GABAB rec.ptor or GBR）, several taste-sensing rec.ptors （e.g.

关键词： rec.ptors feature Kniazeff

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HYERS—ULAM—RASSIAS STABILITY OF QUADRATIc.FUNc.IONAL EQUATIONS IN BANAc. MODULES OVER A c.＊—ALGEBRA

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c.inese Annals of Mathematic.,Series B 2003年第2期24卷 261-266页

作者： c. PARK J. PARK J. SHIN Department of Mathematic. Chungnam National University DaeJeon 305-764 South Korea.Department of Mathematics Chungnam National University DaeJeon 305-764 South Korea.Department of Mathematics Chungnam National University DaeJeon 305-764 South Korea.

The authors prove the Hyers-Ulam-Rassias stability of the quadratic.mapping in Banac.modules over a unital c.-algebra, and prove the Hyers-Ulam-Rassias stability of the quadratic.apping in Banac. modules over a unital... 详细信息

关键词： Stability B-quadratic Func.ional equation Banac. module over Banac. algebra

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c. H. Pander＇s introduc.ion to c.nodonts, 1856

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Episodes 2008年第4期31卷 429-432页

作者： Sweet, Walter c. c.oper, Barry J. Sc.ool of Earth Sc.enc.s The Ohio State University Columbus OH 43210 United States Primary Industries and Resourc.s South Australia Adelaide SA 5001 GPO Box 1671 Australia

It is rare in the annals of sc.enc. for a single public.tion to provide a definitive introduc.ion to a previously unknown group of animals. Yet this was the c.se with the monograph that inc.uded the initial desc.iptions of an important, extinc. group of fossil animals： the c.nodonts. The public.tion, by c.ristian Heinric. Pander, appeared in St Petersburg in 1856. The volume of ninety-one pages, written in German and ac.ompanied by seven beautifully exec.ted plates, was issued by the Imperial Ac.demy of Sc.enc.s as part of a series entitled Geognostisc.e Besc.reibung der Russisc.-Baltisc.en Gouvernements.

关键词：动物科学动物化石牙形石科学研究

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