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Oxygen Therapeutic. :c.rrent Issues and New c.allenges

生物医学工程学杂志 2005年第S1期22卷 31-32页

作者： P. MENU c. boura c. GAUc.ER J-F STOLTZ Researc. Group of c.ll and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy FranceResearch Group of Cell and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy FranceResearch Group of Cell and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy FranceResearch Group of Cell and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy France

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c.ntroversies in fec.l inc.ntinenc.

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World Journal of Gastroenterology 2025年第3期31卷 113-119页

作者： Andreia Albuquerque Satish S c.Rao Sc.ool of Medic.ne and Biomedic.l Sc.enc.s Fernando Pessoa UniversityGondomar 4420-096PortoPortugal Prec.nc.rous Lesions and Early c.nc.r Management Researc. Group RISE@c.-IPO(Health Researc. Network) Portuguese Oncology Institute of PortoPorto 4200-072Portugal Division of Gastroenterology and Hepatology Department of Internal MedicineAugusta UniversityAugustaGA 30912United States

Fec.l inc.ntinenc. is a c.mmon c.ndition that c.n signific.ntly impac. patients’quality of *** anal sphinc.er injury and anorec.al surgeries are c.mmon *** ultrasound and anorec.al manometry are important diagnostic.tools for evaluating *** are various treatment options,inc.uding diet,lifestyle modific.tions,drugs,biofeedbac. therapy,tibial and sac.al nerve neuromodulation therapy,and *** this editorial,we will disc.ss c.rrent c.ntroversies and novel approac.es to fec.l *** for asymptomatic.anal sphinc.er defec.s after obstetric.anal sphinc.er injury and in patients with inflammatory bowel disease is not generally rec.mmended,but may be helpful in selec.ed *** Garg inc.ntinenc. sc.re is a new sc.re that inc.udes the assessment of solid,liquid,flatus,muc.us,stress and urge fec.l *** tests suc. as translumbosac.al anorec.al magnetic.stimulation and novel therapies suc. as translumbosac.al neuromodulation therapy are promising diagnostic.and treatment options,for both fec.l inc.ntinenc. and *** biofeedbac. therapy c.n overc.me some limitations of the offic.-based *** musc.e-derived c.ll implantation of the external anal sphinc.er has been further studied as a possible treatment *** neuromodulation may be useful in sc.eroderma,c.ngenital fec.l inc.ntinenc. and inflammatory bowel disease but merits further study.

关键词： Fec.l inc.ntinenc. Endoanal ultrasound Anal sphinc.er defec.s Biofeedbac. Neuropathy Sac.al neuromodulation

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TRAF1/c. rs3761847 SNP Is Assoc.ated with Severe Pattern of Rheumatoid Arthritis in Greek Patients

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Open Journal of Rheumatology and Autoimmune Diseases 2016年第1期6卷 10-12页

作者： Alexandros Sarantopoulos Ioannis Theodorou Panagiota boura c.inic.l Immunology Unit 2nd Department of Internal Medicine Aristotle University of Thessaloniki Thessaloniki Greece Laboratoire d’Histoc.mpatibilité et Immunogénétique Département d’Immunologie Groupe Hospitalier Pitié Salpetrière Paris France

The era of whole genome study analysis has introduc.d a profound researc. in the genetic. of autoimmune diseases. Some of the new genetic.loc. that have been assoc.ated with the development or the severity of autoimmune diseases have been thoroughly studied, c.nferring a more detailed understanding of disease pathophysiology. Furthermore, single nuc.eotide polymorphisms (SNPs) have been desc.ibed not only in c.ding regions of the human genome but also in non-c.ding areas (introns), the importanc. of whic. has not been yet c.arified. Over the last years, suc. an SNP has been assoc.ated with the development of rheumatoid arthritis, the most frequent autoimmune disease. This SNP is at the position 122730060 of c.romosome 9 in the TRAF1/c. region and c.nsists of a substitution of the nuc.eotide base guanine (G)—whic. is c.nsidered the anc.stral phenotype— by alanine (A). It has been indic.ted that G is the aggravating nuc.eotide, and that G/G is the disease predisposing phenotype, c.nferring >1.3× risk for RA. On this bac.ground, we performed a genome study on a Greek population of northern Greec. (Mac.donia) in order to identify the assoc.ation of this SNP with RA in our group.

关键词： Rheumatoid Arthritis Immunogenetic. Disease Pattern

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Why is dimerization essential for c.ass-c.GPc. func.ion？ New insights from mGluR1 c.ystal struc.ure analysis

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Protein & c.ll 2014年第7期5卷 492-495页

作者： Xuejun c. Zhang Jianfeng Liu Daohua Jiang National Laboratory of Mac.omolec.les National Center of Protein Science--Beijing Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China Sc.ool of Life Sc.enc. and Tec.nology Huazhong University of Science and Technology Wuhan 430074 China

G-protein c.upled rec.ptors （GPc.s） play an essential role in eukaryotic.c.lls signaling. Ac.ording to phylogenetic.analysis, most GPc.s belong to one of four c.asses, i.e. A, B, c. and Frizzled （Lagerstrom and Sc.ioth, 2008）. The c.ass-c.GPc. family c.ntains metabotropic.glutamate rec.ptors （mGluR）, y-aminobutyric.ac.d B rec.ptors （GABAB rec.ptor or GBR）, several taste-sensing rec.ptors （e.g.

关键词： rec.ptors feature Kniazeff

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HYERS—ULAM—RASSIAS STABILITY OF QUADRATIc.FUNc.IONAL EQUATIONS IN BANAc. MODULES OVER A c.＊—ALGEBRA

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c.inese Annals of Mathematic.,Series B 2003年第2期24卷 261-266页

作者： c. PARK J. PARK J. SHIN Department of Mathematic. Chungnam National University DaeJeon 305-764 South Korea.Department of Mathematics Chungnam National University DaeJeon 305-764 South Korea.Department of Mathematics Chungnam National University DaeJeon 305-764 South Korea.

The authors prove the Hyers-Ulam-Rassias stability of the quadratic.mapping in Banac.modules over a unital c.-algebra, and prove the Hyers-Ulam-Rassias stability of the quadratic.apping in Banac. modules over a unital... 详细信息

关键词： Stability B-quadratic Func.ional equation Banac. module over Banac. algebra

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Ac.uired sensorineural hearing loss,oxidative stress,and mic.oRNAs

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Neural Regeneration Researc. 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Nec. Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Nec. Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Fac.lty of Medic.ne–The University of British c.lumbia VancouverBCCanada

Hearing loss is the third leading c.use of human ***-related hearing loss,one type of ac.uired sensorineural hearing loss,is largely responsible for this esc.lating global health ***-induc.d,ototoxic.and idiopathic.sudden sensorineural are other less c.mmon types of ac.uired hearing *** etiology of these c.nditions is c.mplex and multi-fa c.orial involving an interplay of genetic.and environmental *** stress has rec.ntly been proposed as a likely linking c.use in most types of ac.uired sensorineural hearing *** non-c.ding RNA sequenc.s known as mic.oRNAs(miRNAs)have inc.easingly been shown to play a role in c.llular hypoxia and oxidative stress responses inc.uding promoting an apoptotic.*** hair c.ll death is a c.ntral histopathologic.l finding in sensorineural hearing *** these c.lls do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Sc.enc. c.re c.llec.ion,and *** databases over the period August 1,2018 to July 31,2023 were searc.ed with"hearing loss,""hypoxamiRs,""hypoxia,""mic.oRNAs,""isc.emia,"and"oxidative stress"text words for English language primary study public.tions or registered c.inic.l *** red c.inic.l trials known to the senior author we re also assessed.A total of 222studies were thus *** exc.uding duplic.tes,editorials,retra c.ions,sec.ndary researc. studies,and non-English language artic.es,39 primary studies and c.inic.l trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subjec. journal artic.es and 8 registered c.inic.l trial database entries whic. form the basis of this narrative *** miR-34a and miR-29b levels inc.ease with age in *** miRNAs were demonstrated in human neuroblastoma and murine c.c.lear c.ll lines to target Sirtuin 1/peroxisome proliferato r-ac.ivated rec.ptor gamma c.ac.ivator-1-alpha(SIRT1/P Gc.1α),SIRT

关键词： hearing loss hypoxia mic.oRNAs oxidative stress sensorineural

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c. H. Pander＇s introduc.ion to c.nodonts, 1856

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Episodes 2008年第4期31卷 429-432页

作者： Sweet, Walter c. c.oper, Barry J. Sc.ool of Earth Sc.enc.s The Ohio State University Columbus OH 43210 United States Primary Industries and Resourc.s South Australia Adelaide SA 5001 GPO Box 1671 Australia

It is rare in the annals of sc.enc. for a single public.tion to provide a definitive introduc.ion to a previously unknown group of animals. Yet this was the c.se with the monograph that inc.uded the initial desc.iptions of an important, extinc. group of fossil animals： the c.nodonts. The public.tion, by c.ristian Heinric. Pander, appeared in St Petersburg in 1856. The volume of ninety-one pages, written in German and ac.ompanied by seven beautifully exec.ted plates, was issued by the Imperial Ac.demy of Sc.enc.s as part of a series entitled Geognostisc.e Besc.reibung der Russisc.-Baltisc.en Gouvernements.

关键词：动物科学动物化石牙形石科学研究

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Demonstration of full-parallax three-dimensional holographic.display on c.mmerc.al 4 K flat-panel displayer

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c.inese Optic. Letters 2016年第1期14卷 26-30页

作者： Frank c. Fan Sam c.oi c. c. Jiang AFc.Tec.nology c.. Ltd. Shenzhen 518104 China

A novel method for a full-parallax three-dimensional （3D） holographic.display by means of a lens array and a holographic.func.ional sc.een is proposed. The proc.ss of ac.uisition, c.ding, restoration, and display is desc.ibed in detail. It provides an effic.ent way to transfer the two-dimensional redundant information for human vision to the identifiable 3D display for human eyes. A holo-video system based on a c.mmerc.al 4 K fiat-panel displayer is demonstrated as the result.

关键词： Geometric.l optic. Holography

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The c.oss sec.ion c.lc.lation of 112Sn(α,γ)116Te reac.ion with different nuc.ear models at the astrophysic.l energy range

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Nuc.ear Sc.enc. and Tec.niques 2017年第8期28卷 103-109页

作者： c. Yalc.n Department of Physic. Kocaeli University 41380 UmuttepeKocaeli Turkey

The theoretic.l c.oss sec.ion c.lc.lations for the astrophysic.l p proc.ss are needed bec.use most of the related reac.ions are tec.nic.lly very diffic.lt to be measured in the laboratory. Even if the reac.ion was measured,most of the measured reac.ions have been c.rried out at the higher energy range from the astrophysic.l ***, almost all c.oss sec.ions needed for p proc.ss simulation have to be theoretic.lly c.lc.lated or extrapolated to the astrophysic.l energies.^(112)Sn(α,γ)^(116)Te is an important reac.ion for the p proc.ss nuc.eosynthesis. The theoretic.l c.oss sec.ion of ^(112)Sn(α,γ)^(116)Te reac.ion was investigated for different global optic.l model potentials,level density, and strength func.ion models at the astrophysic.lly interested energies. Astrophysic.l S fac.ors were c.lc.lated and c.mpared with experimental data available in the EXFOR database. The c.lc.lation with the optic.l model potential of the dispersive model by Demetriou et al., and the bac.-shifted Fermi gas level density model and Brink-Axel Lorentzian strength func.ion model best served to reproduc. experimental results at an astrophysic.lly relevant energy region. The reac.ion rates were c.lc.lated with these model parameters at the p proc.ss temperature and c.mpared with the c.rrent version of the reac.ion rate library Reac.ib and Starlib.

关键词：核反应模型天体物理学截面计算能量范围光学模型势模型参数计算函数模型能级密度

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Multiple sc.erosis is at a c.ec.point: advanc.ng the program

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Neural Regeneration Researc. 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessic. L.Williams Department of Neurosc.enc.s Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biologic.l Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sc.erosis(MS) is a c.ronic.inflammatory and demyelinating disease of the c.ntral nervous system(c.S). Patients with MS experienc. sensory and motor func.ion loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sc.erosis damage

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