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Optimal proximal resection margin distance for gastrectomy in advanced gastric cancer

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World Journal of Gastroenterology 2020年第18期26卷 2232-2246页

作者： Amy kim Beom Su kim Jeong Hwan Yook byung Sik kim Division of Stomach Surgery Department of SurgeryAsan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea Department of Surgery Korea University Medical Center Ansan HospitalAnsanGyeonggi-do 15355South Korea

BACKGROUND The conventional guidelines to obtain a safe proximal resection margin(PRM)of5-6 cm during advanced gastric cancer(AGC)surgery are still applied by many surgeons across the *** recent studies have raised questions regarding the need for such extensive resection,but without reaching *** study was designed to prove that the PRM distance does not affect the prognosis of patients who undergo gastrectomy for *** To investigate the influence of the PRM distance on the prognosis of patients who underwent gastrectomy for *** Electronic medical records of 1518 patients who underwent curative gastrectomy for AGC between June 2004 and December 2007 at Asan Medical Center,a tertiary care center in Korea,were reviewed retrospectively for the *** demographics and clinicopathologic outcomes were compared between patients who underwent surgery with different PRM distances using one-way ANOVA and Fisher’s exact test for continuous and categorical variables,*** influence of PRM on recurrence-free survival and overall survival were analyzed using Kaplan-Meier survival analysis and Cox proportional hazard *** The median PRM distance was 4.8 cm and 3.5 cm in the distal gastrectomy(DG)and total gastrectomy(TG)groups,*** cohorts in the DG and TG groups were subdivided into different groups according to the PRM distance;≤1.0 cm,1.1-3.0 cm,3.1-5.0 cm and>5.0 *** DG and TG groups showed nostatistical difference in recurrence rate(23.5%vs 30.6%vs 24.0%vs 24.7%,P=0.765)or local recurrence rate(5.9%vs 6.5%vs 8.4%vs 6.2%,P=0.727)according to the distance of *** both groups,Kalpan-Meier analysis showed no statistical difference in recurrence-free survival(P=0.467 in DG group;P=0.155 in TG group)or overall survival(P=0.503 in DG group;P=0.155 in TG group)according to the PRM *** analysis using Cox proportional hazard model revealed that in both groups,there was no significant differ

关键词： Stomach neoplasms Gastrectomy Margins of excision Prognosis Recurrence

Aging Behavior of Mg-Y-Zr and Mg-Nd-Zr Cast Alloys

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Journal of Materials Science & Technology 2008年第1期24卷 80-84页

作者： Yang-Do kim nam-Hyun Kang Il-Guk Jo Kyung-Hyun kim In-Bae kim School of Materials Science and Engineering Pusan National University 30 Jangjun-dongGeumjeong-guBusan 609-735Korea Deptartment of Materials Engineering Korea Institute of Machinery & Materials 66 Sangnam-dongChangwonGyeongsangnam-do 641-010Korea

Aging behavior of Mg-3.6Y-0.5Zr and ***-0.5Zr alloys was investigated by microhardness measurement and transmission electron *** the case of Mg-Y-Zr alloy,the presence ofβ″phase,a major strength- ener,having base centered orthorhombic structure with its lattice constants of a-（β″）=0.64 nm,b-（β″）=2.22 nm, and c-（β″）=0.52 nm was *** the case of Mg-Nd-Zr alloy aged at 250℃,the presence ofβ″andβ′phases was *** crystal structure ofβ″phase was found to be DO-（19） and its orientation relationships with Mg matrix were [0001]-（β″）//[0001]-（Mg） and [01（？）0]-（β″）//[01（？）0]-（Mg）.Theβ′phase had face centered cubic structure and its orientation relationships with Mg matrix were [011]-（β′）//[0001]-（Mg） and [（？）1（？）]β′//[（？）110]）-（Mg）. The ***-0.5Zr alloy showed higher hardness compared with Mg-3.6Y-0.5Zr alloy.

关键词： Mg-Y-Zr alloy Mg-Nd-Zr alloy Precipitation sequence

Effects of PWHT on Microstructure and Mechanical Properties of Weld Metals of Ni-Based Superalloy 617 and 263 for Hyper-Supercritical Power Plants

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Acta Metallurgica Sinica(English Letters) 2016年第12期29卷 1107-1118页

作者： Jeong Kil kim Hae Ji Park Deog nam Shim Doosan Heavy Industries and Construction ChangwonGeongnam Korea

It is well known that solid solution-strengthened alloy 617 and γ′ precipitation-strengthened alloy 263 have excellent mechanical properties and corrosion resistance at high temperatures. Hyper-supercritical power plants work at temperatures above 700 ℃, and these superalloys are considered candidate materials for steam turbines components of these power plants. In this study, gas tungsten arc weldability of these superalloys was evaluated, and the effects of post- weld heat treatment （PWHT） on the microstructural characteristics and the mechanical properties of their weld metals were investigated. Scanning transmission electron microscopy, energy-dispersive spectroscopy and electron probe microanalysis were utilized for the investigation. The experimental results confirmed that these weld metals had different characteristics in microstructure and mechanical properties. PWHT resulted in the precipitation of intergranular carbides, γ′ particles and an increase in tensile strength of these superalloy weld metals. Furthermore, fine γ′ particles, which were not detected in the as-welded metal of alloy 263, were precipitated after PWHT and those particles were the reason for the drastic increase in tensile strength.

关键词： Superalloy Welding Precipitation Segregation

Uniaxially crumpled graphene as a platform for guided myotube formation

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Microsystems & Nanoengineering 2019年第1期5卷 144-153页

作者： Junghoon kim Juyoung Leem Hong nam kim Pilgyu Kang Jonghyun Choi Md Farhadul Haque Daeshik Kang SungWoo nam Department of Mechanical Science and Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA Center for BioMicrosystems Brain Science InstituteKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea Department of Mechanical Engineering George Mason UniversityFairfaxVA 22030USA Department of Mechanical Engineering Ajou UniversitySuwon 16499Republic of Korea Department of Materials Science and Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA

Graphene,owing to its inherent chemical inertness,biocompatibility,and mechanical flexibility,has great potential in guiding cell behaviors such as adhesion and ***,due to the two-dimensional(2D)nature of graphene,the microfabrication of graphene into micro/nanoscale patterns has been widely adopted for guiding cellular *** this study,we report crumpled graphene,i.e.,monolithically defined graphene with a nanoscale wavy surface texture,as a tissue engineering platform that can efficiently promote aligned C2C12 mouse myoblast cell *** imparted out-of-plane,nanoscale crumpled morphologies to flat graphene via compressive straininduced *** C2C12 mouse myoblast cells were seeded on the uniaxially crumpled graphene,not only were the alignment and elongation promoted at a single-cell level but also the differentiation and maturation of myotubes were enhanced compared to that on flat *** results demonstrate the utility of the crumpled graphene platform for tissue engineering and regenerative medicine for skeletal muscle tissues.

关键词： Uniaxial graphene alignment

Study on frictional behavior of carbon nanotube thin films with respect to surface condition

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Friction 2018年第4期6卷 432-442页

作者： Youn-Hoo HWANG byung-Soo MYUNG Hyun-Joon kim Department of Precision Mechanical Engineering Kyungpook National University

In this work, tribological characteristics of thin films composed of entangled carbon nanotubes(CNTs) were investigated. The surface roughness of CNT thin films fabricated via a dip‐coating process was controlled by squeezing during the process with an applied normal force ranging from 0 to 5 kgf. Raman spectra and scanning electron microscopy(SEM) images of the thin films were obtained to estimate the influence of the squeezing process on the crystallinity of the CNTs. The analysis revealed that squeezing could reduce surface roughness, while preserving the crystallinity of the CNTs. Moreover, the surface energy of the cover glass used to press the CNT thin film was found to be the critical factor controlling surface roughness. A micro‐tribometer and macro‐tribometer were used to assess the tribological characteristics of the CNT thin film. The results of the tribotest exhibited a correlation between the friction coefficient and surface roughness. Dramatic changes in friction coefficient could be observed in the micro‐tribotest, while changes in friction coefficient in the macro‐tribotest were not significant.

关键词： carbon nanotubes friction surface roughness surface energy squeezing process UV irradiation

Sleep Posture Classification Using RGB and Thermal Cameras Based on Deep Learning Model

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1729-1755页

作者： Awais Khan Chomyong kim Jung-Yeon kim Ahsan Aziz Yunyoung nam Department of ICT Convergence Soonchunhyang UniversityAsan31538Korea ICT Convergence Research Center Soonchunhyang UniversityAsan31538Korea Emotional and Intelligent Child Care Convergence Research Center Soonchunhyang UniversityAsan31538Korea

Sleep posture surveillance is crucial for patient comfort,yet current systems face difficulties in providing compre-hensive studies due to the obstruction caused by *** posture assessment remains challenging because of the complex nature of the human body and variations in sleep ***,this study introduces an innovative method utilizing RGB and thermal cameras for comprehensive posture classification,thereby enhancing the analysis of body position and *** method begins by capturing a dataset of sleep postures in the form of videos using RGB and thermal cameras,which depict six commonly adopted postures:supine,left log,right log,prone head,prone left,and prone *** study involves 10 participants under two conditions:with and without ***,the database is normalized into a video *** subsequent step entails training a fine-tuned,pretrained Visual Geometry Group(VGG16)and ResNet50 *** the third phase,the extracted features are utilized for *** fourth step of the proposed approach employs a serial fusion technique based on the normal distribution to merge the vectors derived from both the RGB and thermal ***,the fused vectors are passed to machine learning classifiers for final *** dataset,which includes human sleep postures used in this study’s experiments,achieved a 96.7%accuracy rate using the Quadratic Support Vector Machine(QSVM)without the ***,the Linear SVM,when utilized with a blanket,attained an accuracy of 96%.When normal distribution serial fusion was applied to the blanket features,it resulted in a remarkable average accuracy of 99%.

关键词： Human sleep posture VGG16 deep learning ResNet50 fusion machine learning

Intelligent Resource Allocations for Software-Defined Mission-Critical IoT Services

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Computers, Materials & Continua 2022年第11期73卷 4087-4102页

作者： Chaebeen nam Sa Math Prohim Tam Seokhoon kim Department of Software Convergence Soonchunhyang UniversityAsan31538Korea Department of Computer Software Engineering Soonchunhyang UniversityAsan31538Korea

Heterogeneous Internet of Things(IoT)applications generate a diversity of novelty applications and services in next-generation networks(NGN),which is essential to guarantee end-to-end(E2E)communication resources for both control plane(CP)and data plane(DP).Likewise,the heterogeneous 5th generation(5G)communication applications,including Mobile Broadband Communications(MBBC),massive Machine-Type Commutation(mMTC),and ultra-reliable low latency communications(URLLC),obligate to perform intelligent Quality-of-Service(QoS)Class Identifier(QCI),while the CP entities will be suffered from the complicated massive HIOT ***,the existing management and orchestration(MANO)models are inappropriate for resource utilization and allocation in large-scale and complicated network *** cope with the issues mentioned above,this paper presents an adopted software-defined mobile edge computing(SDMEC)with a lightweight machine learning(ML)algorithm,namely support vector machine(SVM),to enable intelligent MANO for real-time and resource-constraints IoT applications which require lightweight computation ***,the SVM algorithm plays an essential role in performing QCI ***,the software-defined networking(SDN)controller allocates and configures priority resources according to the SVM classification ***,the complementary of SVM and SDMEC conducts intelligent resource MANO for massive QCI environments and meets the perspectives of mission-critical communication with resource constraint *** on the E2E experimentation metrics,the proposed scheme shows remarkable outperformance in key performance indicator(KPI)QoS,including communication reliability,latency,and communication throughput over the various powerful reference methods.

关键词： Mobile edge computing Internet of Things software defined networks traffic classification machine learning resource allocation

Toward Systems Understanding of Leaf Senescence： An Integrated Multi-Omics Perspective on Leaf Senescence Research

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Molecular Plant 2016年第6期9卷 813-825页

作者： Jeongsik kim Hye Ryun Woo Hong Gil nam Center for Plant Aging Research Institute for Basic Science (IBS) Daegu 42988 Republic of Korea Department of New Biology DGIST Daegu 42988 Republic of Korea

Leaf senescence is a complex but tightly regulated developmental process involving a coordinated sequence of multiple molecular events, which ultimately leads to death of the leaf. Efforts to understand the mechanistic principles underlying leaf senescence have been largely made by transcriptomic, proteomic, and metabolomic studies over the past decade. This review focuses on recent milestones in leaf senes- cence research obtained using multi-omics technologies, as well as future endeavors toward systems understanding of leaf senescence processes. In particular, we discuss recent advances in understanding molecular events during leaf senescence through genome-wide transcriptome analyses in Arabidopsis. We also describe comparative transcriptome analyses used to unveil the commonality and diversity of regulatory mechanisms governing leaf senescence in the plant kingdom. Finally, we provide current illustrations of epigenomic, proteomic, and metabolomic landscapes of leaf senescence. We envisage that integration of multi-omics leaf senescence data will enable us to address unresolved questions regarding leaf senescence, including determining the molecular principles that coordinate concurrent and ordered changes in biological events during leaf senescence.

关键词： leaf senescence transcriptomics epigenomics proteomics metabolomics multi-omics

Predictors for difficult cecal insertion in colonoscopy: The impact of obesity indices

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World Journal of Gastroenterology 2017年第13期23卷 2346-2354页

作者： Soo Yun Moon byung Chang kim Dae Kyung Sohn Kyung Su Han Bun kim Chang Won Hong Bum Joon Park Kum Hei Ryu Ji Hyung nam Center for Colorectal Cancer Research Institute and HospitalNational Cancer Center Department of Surgery School of MedicineKyung Hee University Center for Cancer Prevention and Detection Research Institute and HospitalNational Cancer Center

AIM To identify the factors influencing cecal insertion time(CIT) and to evaluate the effect of obesity indices on CIT. METHODS We retrospectively reviewed the data for participants who received both colonoscopy and abdominal computed tomography(CT) from February 2008 to May 2008 as part of a comprehensive health screening program. Age, gender, obesity indices [body mass index(BMI), waist-to-hip circumference ratio(WHR), waist circumference(WC), visceral adipose tissue(VAT)volume and subcutaneous adipose tissue(SAT) volume on abdominal CT], history of prior abdominal surgery, constipation, experience of the colonoscopist, quality of bowel preparation, diverticulosis and time required to reach the cecum were analyzed. CIT was categorized as longer than 10 min(prolonged CIT) and shorter than or equal to 10 min, and then the factors that required a CIT longer than 10 min were *** A total of 1678 participants were enrolled. The mean age was 50.42 ± 9.931 years and 60.3% were men. The mean BMI, WHR, WC, VAT volume and SAT volume were 23.92 ± 2.964 kg/m2, 0.90 ± 0.076, 86.95 ± 8.030 cm, 905.29 ± 475.220 cm3 and 1707.72 ± 576.550 cm3, respectively. The number of patients who underwent abdominal surgery was 268(16.0%). Colonoscopy was performed by an attending physician alone in 61.9% of cases and with the involvement of a fellow in 38.1% of cases. The median CIT was 7 min(range 2-56 min, IQR 5-10 min), and mean CIT was 8.58 ± 5.291 min. Being female, BMI, VAT volume and involvement of fellow were significantly associated with a prolonged CIT in univariable analysis. In multivariable analysis, being female(OR = 1.29, P = 0.047), lower BMI(< 23 kg/m2)(OR = 1.62, P = 0.004) or higher BMI(≥ 25 kg/m2)(OR = 1.80, P < 0.001), low VAT volume(< 500 cm3)(OR = 1.50, P = 0.013) and fellow involvement(OR = 1.73, P < 0.001) were significant predictors of prolonged CIT. In subgroup analyses for gender, lower BMI or higher BMI and fellow involvement were predictors for prolon

关键词： Visceral obesity Difficult colonoscopy Cecal insertion time Body mass index Female