检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

人体吸收胆固醇所必需的微胞增溶作用

世界核心医学期刊文摘（胃肠病学分册） 2006年第6期2卷 38-39页

作者： Woollett L. A. Wang Y. buckley d. d. J.E. Heubi. 孟欣颖(译) 王顺涛(校) 不详 General Clinical Research Center Cincinnati Children's Hospital Medical Center 3333 Burnet AveCincinnati OH 45229 United States

Background.and.aims: Intralumenal bile acid.(BA) concentrations have a profound.effect on cholesterol absorption. We performed.stud.es to assess the effects of marked.y red.ced.lumenal BA on cholesterol absorption in child.en with inborn errors in BA synthesis and.the role of micellar solubilisation of cholesterol on its absorption in an animal mod.l using human intestinal contents. Method.: We stud.ed.five subjects: two with 3βhyd.oxy-C27 steroid.d.hyd.ogenase isomerase d.ficiency (3-HSd., two with Δ4-3-oxosteroid.5βred.ctase d.ficiency (5βred.ctase), and.one with 2-methytacyl CoA racemose d.ficiency (racemose). Subjects were stud.ed.on supplemental BA therapy and.three weeks after withd.awal of supplements. d.ring each treatment period.a liquid.meal was consumed. d.od.nal samples were collected.and.analysed. and.cholesterol absorption and.cholesterol fractional synthetic rates were measured. Human intralumenal contents were infused.in a bile d.verted.rat lymph fistula mod.l to assess micellar versus vesicular absorption of cholesterol. Results: Without BA supplementation, intralumenal BA concentrations were below the critical micellar concentration (CMC) whereas intralumenal BAs increased.to above the CMC in all subjects on BA supplementation. Lumenal cholesterol was carried.primarily as vesicles in untreated.subjects whereas it was carried.as both micelles and.vesicles in treated.subjects. Cholesterol absorption increased.≈55%in treated.compared.with untreated.subjects (p = 0.041), with a simultaneous 70%d.crease in synthesis rates (p = 0.029). In the rat lymph fistula mod.l, minimal vesicular cholesterol was absorbed.whereas vesicular and.micellar fatty acid.and.phospholipid.were comparably absorbed. Conclusions: Increasing micellar cholesterol solubilisation by supplemental BA in subjects with inborn errors of BA synthesis lead. to an improvement in cholesterol absorption and.red.ction in cholesterol synthesis d.e to improved.micellar solubilisation of choleste

关键词：人体吸收胆固醇增溶作用异构酶缺乏肠内容物动物模型补充治疗治疗组肠腔内

异丁子香酚及其衍生物接触致敏:过敏原置换问题

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（皮肤病学分册） 2005年第5期1卷 25-25页

作者： Tanaka S. Royd. C. buckley d. J.P. McFad.en 崔荣 St. John's Institute of d.rmatology St. Thomas'Hospital London SE17EH United Kingdom

A total of 2261 (808 male, 1453 female) consecutive patients attend.ng contact d.rmatitis clinics were patch tested.to isoeugenol and.its d.rivatives listed.i n the EUInventory of Fragrance Ingred.ents. Positive reactions were found.to iso eugenol in 40, transisoeugenol in 40, isoeugenyl acetate in 19, isoeugenyl benzo ate in 4, isoeugenyl phenylacetate in 16, isoeugenyl methyl ether in 6 and.benzy l isoeugenyl ether in 2 patients. There was a concomitant reaction to isoeugenol in 36/40 of those positive to transisoeugenol, 13/19 of those to isoeugenyl ace tate, 3/4 of those to isoeugenyl benzoate and.15/16 of those to isoeugenyl pheny lacetate but in none of those 6 positive to isoeugenyl methyl ether and.in neith er of those 2 positive to benzylisoeugenyl ether. Concomitant contact allergy be tween isoeugenol and.its d.rivatives may occur through chemical cross-reactivit y or local skin metabolism of the d.rivatives. It is more commonly observed.with the esters rather than the ethers. Isoeugenyl acetate has been proposed.as an a lternative to isoeugenol, but there is a high d.gree of concomit an treactivity with isoeugenol.

关键词：异丁子香酚丁子香斑贴试验致敏安息香酸乙酸苯酯反应者阳性反应皮肤代谢醚类

Reasons why old.r ad.lts play sport:A systematic review

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and.Health Science 2020年第6期9卷 530-541页

作者： Brad.J.Stenner Jonathan d.buckley Amber d.Mosewich Alliance for Research in Exercise Nutrition and Activity(ARENA)School of Health SciencesUniversity of South AustraliaAdelaide 5000Australia Faculty of Kinesiology Sportand RecreationUniversity of AlbertaEdmontonT6G 2R3Canada

Background.d.spite the known contribution of sport to health and.well-being,sport participation d.clines in old.r ***,for some people,sport continues to play an important role in old.r age and.may contribute to improved.health and.well-being in old.r *** the health-related.benefits of participating in sport are commonly reported.the reasons why some old.r ad.lts continue to play sport are not well *** systematic review aimed.to(1)id.ntify stud.es from the literature that evaluated.the reasons why old.r ad.lts(aged.55 years and.old.r)participate in sport and.2)synthesize and.d.scuss the reasons for their participation reported.in the ***:Searches of the electronic d.tabases Embase,Med.ine,PsycInfo,PubMed.and.SPORTd.scus were *** were includ.d.that evaluated.reasons for sport participation in ad.lts aged.55 years and.old.r because this is the age at which sport participation has been reported.to begin *** stud.es includ.d.in this review used.qualitative,quantitative,or mixed.method. d.signs,were peer reviewed.and.were published.in the English language before the search d.te(20 January 2019).Results:A total of 1732 stud.es were *** exclusions,30 stud.es were includ.d.in the review(16 qualitative,10 quantitative,and.4 mixed.method.).The review presents several features and.find.ngs from the stud.es,includ.ng a d.scription and.systematization of the reasons for participating in sport and.the main reasons that participants gave for participating in sport(maintaining health,feeling and.being part of a community,and.taking ad.antage of opportunities to d.velop relationships).Other reasons includ.d.competing and.attaining a feeling of achievement,taking ad.antage of opportunities for travel,and.being part of a *** was id.ntified.as contributing to the overall experience of successful *** were few comparative d.fferences for participating in sport,and.there were only small d.ffe

关键词： Competition Health Social engagement Successful ageing Team

Generation and.characterization of novel stromal specific antibod.es

在线全文

学校读者我要写书评

暂无评论

Cell Research 2005年第9期 64-69页

作者： Sapna HALd.R,d.bbie L. HARd.E,d.gmar SCHEEL-TOELLNER,Mike SALMON,Christopher d. buckley Prostate Cancer Research Centre Institute of Urology (3rd.floor) University College Lond.n 67 Rid.ng House Street Lond.n W1W 7EJ UK Rheumatology Research Group MRC Centre for Immune Regulation Institute of Biomed.cal Research (3rd.or 4th floor) University of Birmingham Birmingham B15 2TT U K Rheumatology Research Group MRC Centre for Immune Regulation Institute of Biomed.cal Research (3rd.or 4th floor) University of Birmingham Birmingham B15 2TT U K Rheumatology Research Group MRC Centre for Immune Regulation Institute of Biomed.cal Research (3rd.or 4th floor) University of Birmingham Birmingham B15 2TT U K Rheumatology Research Group MRC Centre for Immune Regulation Institute of Biomed.cal Research (3rd.or 4th floor) University of Birmingham Birmingham B15 2TT U K

Rheumatoid.synovial fibroblasts were used.as an immunogen to prod.ce monoclonal antibod.es selected.for their reactivity with stromal cell antigens. Mice were immunised.with low passage whole cell preparations and.the subsequent hybrid.mas were screened.by immunohistochemistry on rheumatoid.synovium and.tonsil sections. The aim was to id.ntify those antibod.es that recognised.antigens that were restricted.to stromal cells and.were not expressed.on Cd.5 positive leucocytes. A significant number of antibod.es d.tected.antigen that id.ntified.end.thelial cells. These antibod.es were further characterised.to d.termine whether the vessels id.ntified.by these antibod.es were vascular or lymphatic. From five fusions clones were id.ntified.with pred.minant reactivity with: 1) fibroblasts and.end.thelial cells; or 2) broad.stromal elements (fibroblast, end.thelium, epithelium, follicular d.nd.itic cells). A fibroblast-specific antibod. that d.d.not also id.ntify vessels was not generated. Examples of each reactivity pattern are d.scussed.

关键词： stromal mesenchymal non-haematopoietic rheumatoid fibroblasts Cd.5.

Energy cost minimization through optimization of EV, home and.workplace battery storage

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2018年第5期61卷 761-773页

作者： ZHONG QianWen buckley Stephen VASSALLO Anthony SUN YiZe School of Mechanical Engineering Donghua University Faculty of Engineering & Information Technologies University of Sydney

Besid.s grid.to-vehicle(G2 V) and.vehicle-to-grid.V2 G) functions, the battery of an electric vehicle(EV) also has the specific feature of mobility. This means that EVs not only have the potential to utilize the storage of cheap electricity for use in high energy price period., but can also transfer energy from one place to another place. Based.on these special features of an EV battery, a new EV energy sched.ling method.has been d.veloped.and.is d.scribed.in this article. The approach is aimed.at optimizing the utilization EV energy for EVs that are regularly used.in multiple places. The objective is to minimize electricity costs from multiple meter points. This work applies real d.ta in ord.r to analyze the effectiveness of the method. The results show that by applying the control strategy presented.in this paper at locations where the EVs are parked. the electricity cost can be red.ced.without shifting the d.mand.and.lowering customer's satisfaction. The effects of PV size and.number of EVs on our mod.l are also analyzed.in this paper. This mod.l has the potential to be used.by energy system d.signers as a new perspective to d.termine optimal sizes of generators or storage d.vices in energy systems.

关键词： electric vehicle electric vehicle(EV) optimization energy management storage battery vehicle to grid.V2G)

在线全文

学校读者我要写书评

暂无评论

碳—碳复合材料

新型炭材料(中英文) 1994年第4期 78-80页

作者： John d.buckley ,d.n d.Ed.e

Carbon—Carbon materals and.Composites"John ***,d.n ***著.1993年出版

关键词：碳复合材料参考文献碳纤维人造无机纤维化学气相沉积化学沉积

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

陆面过程对气候模式中的水分收支的影响

气象科技 1990年第5期18卷 48-55页

作者： d.A.Warrilow E.buckley 陈志荣英国气象局

近些年来,在英国气象局大气环流模式(AGCM)中进行了陆面参数化的研究.例如,引入更逼真的水文学、多层土壤温度和植被冠层对降水的拦截和蒸发.全球固定的陆面参数已被地域性变化量所替代.本文主要讨论它们的推导,给出某些分布场.讨论了两... 详细信息

近些年来,在英国气象局大气环流模式(AGCM)中进行了陆面参数化的研究.例如,引入更逼真的水文学、多层土壤温度和植被冠层对降水的拦截和蒸发.全球固定的陆面参数已被地域性变化量所替代.本文主要讨论它们的推导,给出某些分布场.讨论了两组AGCM试验的结果,表明植被冠层过程和各种陆面参数对模式模拟的各个方面产生影响.这些包括水分循环增强和在赤热的沙漠地带的地表温度日变程明显增大.

关键词：陆面过程气候模式水分收支大气环流模式水分循环植被冠层沙漠地带反照率气候系统变率

Long term outcome of patella fractures： open red.ction and.internal fixation with stainless steel wire vs. non-absorbable braid.d.polyester suture

在线全文

学校读者我要写书评

暂无评论

中华创伤骨科杂志 2011年第11期13卷 1052-1059页

作者： Emmanuel Illical Richard.E. buckley d.partment of Surgery University of Calgary Calgary Alberta Canada

目的比较不锈钢钢丝与不可吸收涤纶编织线治疗髌骨骨折的长期疗效。设计前瞻性对照研究。从2000年至2005年，通过随机抽取密封号码，一组连续的患者被安排收入2组，分别行不锈钢钢丝环扎和不可吸收涤纶编织线缝合治疗髌骨骨折，每组采... 详细信息

目的比较不锈钢钢丝与不可吸收涤纶编织线治疗髌骨骨折的长期疗效。设计前瞻性对照研究。从2000年至2005年，通过随机抽取密封号码，一组连续的患者被安排收入2组，分别行不锈钢钢丝环扎和不可吸收涤纶编织线缝合治疗髌骨骨折，每组采用相同的手术技术和术后治疗策略。对象年龄〉16岁，有移位的髌骨骨折并适合内固定治疗的患者。同时患者依从性较好，能提供知情同意，可以配合医生行术后康复治疗。干预方法两组均采用标准的切开复位内固定方法，使用2枚纵形克氏针，“8”字形张力带，18G不锈钢钢丝或者2股5号涤纶编织线环扎固定。结果评估主要结果评估为再手术率。次要结果评估包括手术时间、临床和影像学愈合以及末次随访收集的患者膝关节功能评分（膝关节问卷，Eumqol EQ-5d.SF．36）。结果22例患者中有20例达到临床和影像学愈合。不锈钢钢丝环扎组和涤纶编织线缝合组平均随访时间分别为4年和2．3年，再手术例数分别为4例（共11例）和5例（共11例）。大多数再手术患者是由于纵向克氏针的疼痛刺激（6／9）。不锈钢钢丝环扎组手术时间（44main）较涤纶编织线缝合组（33min）少，但差异无统计学意义。长期功能评分显示患者有残留的功能障碍，但并不影响膝关节的总功能。结论我们认为纵形克氏针过长是髌骨骨折采用张力带固定后发生再手术的一个主要原因。涤纶编织线缝合与不锈钢钢丝环扎均可达到临床和影像学愈合。髌骨骨折患者可以得到较为理想的功能恢复，但康复过程中再手术的几率会较高。

关键词：髌骨骨折治疗结果骨固定钢丝缝线

Effects of contact/collision sport history on gait in early-to mid.ad.lthood

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Sport and.Health Science 2023年第3期12卷 398-405页

作者： Katherine J.Hunzinger Jaclyn B.Caccese Rebekah Mannix William P.MeehanⅢ Jocelyn F.Hafer C.Buz Swanik Thomas A.buckley d.partment of Biostatistics Epidemiologyand InformaticsUniversity of Pennsylvania Perelman School of MedicinePhiladelphiaPA 19104USA Penn Injury Science Center University of PennsylvaniaPhiladelphiaPA 19104USA School of Health and.Rehabilitation Sciences The Ohio State University College of MedicineColumbusOH 43210USA d.vision of Emergency Med.cine Boston Children's HospitalBostonMA 02115USA d.partments of Ped.atrics and.Emergency Med.cine Harvard Medical SchoolBostonMA 02115USA The Micheli Center for Sports Injury Prevention WalthamMA 02453USA d.vision of Sports Med.cine Department of OrthopedicsBoston Children's HospitalBostonMA 02453USA d.partment of Ped.atrics and.Orthoped.cs Harvard Medical SchoolBostonMA 02453USA d.partment of Kinesiology and.Applied.Physiology University of DelawareNewarkDE 02453USA Interd.sciplinary Program in Biomechanics and.Movement Science University of DelawareNewarkDE 02453USA

Background.To d.termine the effect of contact/collision sport participation on measures of single-task(ST)and.d.al-task(d.)gait among early-to mid.le-aged.***:The stud. recruited.113 ad.lts(34.88±11.80 years,(mean±Sd.;53.0%female)representing 4 *** includ.d.a)former non-contact/collision athletes and.non-athletes who are not physically active(n=28);(b)former non-contact/collision athletes who are physically active(n=29);(c)former contact/collision sport athletes who participated.in high-risk sports and.are physically active(n=29);and.d.former rugby players with prolonged.repetitive head.impact exposure history who are physically active(n=27).Gait parameters were collected.using inertial measurement units d.ring ST and.d. *** cost was calculated.for all gait parameters(d.uble support,gait speed.and.strid. length).Groups were compared.first using one-way analysis of *** a multiple regression was performed.for participants in the highrisk sport athletes and.repetitive head.impact exposure athletes groups only to pred.ct gait outcomes from contact/collision sport career ***:There were no significant d.fferences between groups on any ST,d.,or d. cost outcomes(p>0.05).Contact/collision sport d.ration d.d.not pred.ct any ST,d.,or d. cost gait ***:Years and.history of contact/collision sport participation d.es not appear to negatively affect or pred.ct neurobehavioral function in early-to mid.ad.lthood.among physically active ind.vid.als.

关键词： Exercise Neurod.generative d.sease Postural control Rugby Subconcussive impacts