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Mapping the Dementia Research Area at the Micro-Level Using Co-terms Analysis and Positioning for Traditional Herbal Medicine

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Chinese Journal of Integrative Medicine 2014年第9期20卷 706-711页

作者： bu-yeo kim Jong Seok Kang ung-Soo Han Won Kyung Jeon Herbal Medicine Research Division Korea Institute of Oriental MedicineDaejeon 305-811Republic of Korea Information Analysis Center Korea Institute of S&T InformationSeoul 130-741Republic of Korea Department of Biological Science Konkuk UniversitySeoul 143-701Republic of Korea

Objective： To identify the position of traditional herbal medicine in dementia research field using mapping technology. Methods： Keywords for dementia and traditional herbal medicine for treating dementia were used to extract scientific articles from the Web of Science database from January 2000 to July 2010. A co- occurrence matrix was created based on the concurrent set of author＇s keywords occurring in each scientific article, and technology network maps were created from similarity index matrices. Results： Twenty specialized research areas were identified in the dementia field, and the relationship strength was 0.2-0.6. Many research fields were associated with diagnosis and risk factors for dementia. Additionally, the mechanism or cause of dementia is an actively studied field. Traditional herbal medicine for treating dementia was located on a map near the cortical dementia diagnosis and therapy, and frontotemporal dementia research field with a relationship strength of 0.53 and 0.31-0.33 respectively, which demonstrates that traditional herbal medicine for dementia occupies an independent research area with a relationship to existing scientific research fields. Conclusion： Traditional herbal medicine can provide an alternative and complementary approach for treating dementia as evidenced by a scientific mapping analysis.

关键词： dementia mapping positioning traditional herbal medicine

Advances in Wireless,Batteryless,Implantable Electronics for Real‑Time,Continuous Physiological Monitoring

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Nano-Micro Letters 2024年第3期16卷 254-302页

作者： Hyeonseok kim Bruno Rigo Gabriella Wong Yoon Jae Lee Woon‑Hong yeo IEN Center for Wearable Intelligent Systems and Healthcare Georgia Institute of TechnologyAtlantaGA 30332USA George W.Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA School of Electrical and Computer Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Wallace H.Coulter Department of Biomedical Engineering Georgia Tech and Emory University School of MedicineAtlantaGA 30332USA Parker H.Petit Institute for Bioengineering and Biosciences Institute for MaterialsInstitute for Robotics and Intelligent MachinesGeorgia Institute of TechnologyAtlantaGA 30332USA

This review summarizes recent progress in developing wireless,batteryless,fully implantable biomedical devices for real-time continuous physiological signal monitoring,focusing on advancing human health *** considerations,such as biological constraints,energy sourcing,and wireless communication,are discussed in achieving the desired performance of the devices and enhanced interface with human *** addition,we review the recent achievements in materials used for developing implantable systems,emphasizing their importance in achieving multi-functionalities,biocompatibility,and *** wireless,batteryless devices offer minimally invasive device insertion to the body,enabling portable health monitoring and advanced disease ***,we summarize the most recent practical applications of advanced implantable devices for human health care,highlighting their potential for immediate commercialization and clinical uses.

关键词： Implantable electronics Biomedical systems Batteryless devices Wireless electronics Physiological signal monitoring

Machine-learned wearable sensors for real-time hand-motion recognition: toward practical applications

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National Science Review 2024年第2期11卷 231-263页

作者： Kyung Rok Pyun Kangkyu Kwon Myung Jin Yoo Kyun Kyu kim Dohyeon Gong Woon-Hong yeo Seungyong Han Seung Hwan Ko Department of Mechanical Engineering Seoul National University IEN Center for Human-Centric Interfaces and Engineering Institute for Electronics and NanotechnologyGeorgia Institute of Technology School of Electrical and Computer Engineering Georgia Institute of Technology Department of Chemical Engineering Stanford University Department of Mechanical Engineering Ajou University George W.Woodruff School of Mechanical Engineering Georgia Institute of Technology Institute of Advanced Machinery and Design(SNU-IAMD) Seoul National University

Soft electromechanical sensors have led to a new paradigm of electronic devices for novel motion-based wearable applications in our daily lives. However, the vast amount of random and unidentified signals generated by complex body motions has hindered the precise recognition and practical application of this technology. Recent advancements in artificial-intelligence technology have enabled significant strides in extracting features from massive and intricate data sets, thereby presenting a breakthrough in utilizing wearable sensors for practical applications. Beyond traditional machine-learning techniques for classifying simple gestures, advanced machine-learning algorithms have been developed to handle more complex and nuanced motion-based tasks with restricted training data sets. Machine-learning techniques have improved the ability to perceive, and thus machine-learned wearable soft sensors have enabled accurate and rapid human-gesture recognition, providing real-time feedback to users. This forms a crucial component of future wearable electronics, contributing to a robust human–machine interface. In this review, we provide a comprehensive summary covering materials, structures and machine-learning algorithms for hand-gesture recognition and possible practical applications through machine-learned wearable electromechanical sensors.

关键词： wearable sensor soft electronics artificial intelligence machine learning human–machine interfaces gesture recognition

Apocrine hidrocystoma of the conjunctiva

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International Journal of Ophthalmology(English edition) 2012年第2期5卷 247-248页

作者： Boyun kim Nam yeo Kang Department of Ophthalmology Bucheon St. Mary's Hospital College of Medicine The Catholic University of Korea Bucheon Kyunggi-do 420-717 Korea

Dear Sir, I am Dr. Boyun kim, form the Department of Ophthalmology, bucheon St. Mary’s Hospital, bucheon, Korea. I write to present a case report of apocrine hidrocystoma on temporal bulbar conjunctiva. Apocrine hidrocystoma (AH) is a benign cutaneous cystic nodule arising from apocrine glands of Moll [1]. This lesion usually occurs on eyelids and canthus [1,2], ears, chest, shoulders in adults but its occurrence in conjunctiva [3] is

关键词： Figure Apocrine hidrocystoma of the conjunctiva

Injury of thalamocortical connection between the mediodorsal nucleus of the thalamus and the orbitofrontal cortex in a patient with traumatic brain injury

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Neural Regeneration Research 2018年第6期13卷 1118-1120页

作者： Sung Ho Jang Seong Ho kim Sang Seok yeo Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Neurosurgery College of Medicine Yeungnam University Department of Physical Therapy College of Health Sciences Dankook University

The prefrontal cortex（PFC）is responsible for personality expression and various cognitive functions,including working memory,recognition memory,decision making,attention,and motivation（Frey and Petrides,2000,2002;M... 详细信息

关键词： TBI OFC DTI MD

Impact of Fusobacterium nucleatum in the gastrointestinal tract on natural killer cells

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World Journal of Gastroenterology 2021年第29期27卷 4879-4889页

作者： yeon Ji kim bu Kyung kim Seun Ja Park Jae Hyun kim Institute of Gastroenterology Kosin University College of MedicineBusan 49267Spain Department of Internal Medicine Kosin University College of MedicineBusan 49267South Korea

BACKGROUND Gut microbial dysbiosis contributes to the development and progression of colorectal cancer(CRC).Natural killer(NK)cells are involved in early defense mechanisms to kill infective pathogens and tumor cells by releasing chemokines and *** better understand the relationship between the gut microbiome and CRC,it was hypothesized here that a high abundance of Fusobacterium nucleatum(***)in the gastrointestinal tract could cause reduced NK cell *** To identify associations between gastrointestinal tract *** levels and NK cell *** In vitro experiments were performed on NK cells treated with ***,Peptostreptococcus anaerobius,and Parvimonas micra to identify the effects of gut microbiome species on NK *** 24 and 48 h of treatment,NK cell counts were *** parallel studies,C57BL/6 mice were given broadspectrum antibiotics in their drinking water to reduce resident gut *** 3 wk,the mice received the various bacterial species or phosphate-buffered saline(PBS)via oral gavage every 2 d for 6 *** the study end,blood samples were acquired to perform NK cell activity assessment and cytokine *** tissues were collected and analyzed via immunohistochemistry(IHC).RESULTS The data show that after 3 wk of broad-spectrum antibiotic treatment,levels of total bacteria and *** were markedly decreased in *** of *** significantly decreased NK cell activity relative to the activities of cells from mice treated with antibiotics only and *** administration of *** decreased the proportion of NK46+cells based on IHC staining and increased the production of interleukin-1βand tumor necrosis factor-α.CONCLUSION High levels of *** in the gastrointestinal tract reduced NK cell activity in mice,and the decrease in NK cell activity might be affected by increased proinflammatory cytokines after *** treatment.

关键词： Fusobacterium nucleatum Natural killer cells Colorectal cancer

High Temperature Mechanical Properties of Ni-Al-Cr Based Alloys for Advanced Die-Materials Applications

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Journal of Materials Science & Technology 2008年第3期24卷 305-308页

作者： W.Y.kim H.S.kim Y.G.Yoo I.D.yeo Advanced Materials R&D Division Korea Institute of Industrial Technology7-47Songdo-dongYeonsu-gu

In this study, we report on advanced Ni3Al based high temperature structural alloys with Zr and B addition in order to apply in the fields of die-casting and high temperature press forming as die materials. Microstructures and mechanical properties of Ni3Al based intermetallic alloys produced by vacuum arc melting were investigated in terms of phase analysis by using a scanning electron microscope （SEM） equipped with an X-ray energy dispersive spectrometer （EDS）, an X-ray diffractometer （XRD） and tensile test. The duplex microstructural feature consisting of γ＇ matrix phase and small intermetallic dispersoids was observed to be distributed over the whole microstructure. The ultimate tensile strength of the present alloy was superior to commercial iron-based and Ni-based die-materials especially in the high temperature region.

关键词： Intermetallic Die material Alloying effect Mechanical property

Gastric heterotopia of colon found cancer workup in liver abscess:A case report

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World Journal of Clinical Cases 2022年第15期10卷 5012-5017页

作者： Jun Gi Park Jeong Ill Suh yeo Un kim Department of Internal Medicine College of MedicineDongguk UniversityGyeongju 38067South Korea

BACKGROUND Recently reported cases of pyogenic liver abscess associated with colonic cancer in the absence of underlying disease,have included a small number of cases of gastric heterotopia(GHT).GHT is a congenital anomaly composed of ectopic gastric mucosa and can occur anywhere in the gastrointestinal tract but is more frequently encountered in the cervical ***,it is rarely observed in ***,most reported cases of GHT of the colon involved the rectum,and GHT involving the colon proximal to the rectum is *** SUMMARY An 83-year-old male patient presented with fever and a diagnosis of pyogenic liver *** was performed for colon cancer workup and revealed a 1.0 cm sized polyp at the transverse *** polyp was removed by endoscopic mucosal resection by monopolar electrocauterization using a *** examination revealed *** administering intravenous antibiotics,the patient recovered *** GHT in the colon could affect the development of pyogenic liver abscess by enabling hematogenous propagation of Klebsiella pneumoniae through mucosal ***,more study is needed due to the lack of cases.

关键词： Gastric heterotopia Colon Liver abscess Case report

Effects of Mo and Zr on Microstructure,Mechanical Properties and Wear Resistance of Fe-Al Based Alloys

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Journal of Materials Science & Technology 2008年第3期24卷 309-312页

作者： I.D.yeo H.S.kim Y.G.Yoo W.Y.kim Advanced Materials R&D Division Korea Institute of Industrial Technology7-47Songdo-dongYeonsu-gu

In this work the microstructure, mechanical properties and wear resistance of Fe-Al based alloys with various alloying elements were studied. The microstructures were examined by optical and scanning electron microscopy （SEM） equipped with an energy dispersive X-ray spectroscope （EDS）. Two types of alloys were prepared by vacuum arc melting. One is Fe-28Al based alloys （D03 structured） with and without alloying elements such as Mo and Zr. The other one is Fe-35Al based alloys （B2 structured） produced with the same manner. For both types of alloys, Mo addition had found to exhibit an equiaxed microstructure, while dendritic structure was observed to show the effect of Zr addition. These microstructural features were more evinced with increasing content of alloying element. Concerning the mechanical properties and wear resistance, Fe-35Al based alloys were superior to Fe-28Al based alloys over the whole temperature range investigated.

关键词： Fe-Al alloy Intermetallic Mechanical properties Wear resistance