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数字化平台助力手工艺非遗传承的中英案例研究

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中国非物质文化遗产 2021年第2期 113-120页

作者：张朵朵 [英]尼克·布莱恩·金斯湖南大学设计艺术学院英国伦敦玛丽女王学院

当今社会,数字化技术极大程度地影响和改变着手工艺人的日常生活方式和工作方式,数字化工具和数字化平台极大程度地介入和渗透在手工艺生产至销售的全部环节中。中英两国的数字化技术应用,在学习技能、辅助制作、互动交流、商业机会、... 详细信息

当今社会,数字化技术极大程度地影响和改变着手工艺人的日常生活方式和工作方式,数字化工具和数字化平台极大程度地介入和渗透在手工艺生产至销售的全部环节中。中英两国的数字化技术应用,在学习技能、辅助制作、互动交流、商业机会、交易模式和支付渠道等方面有相似之处,同时,由于文化传统和社会政策环境不同而各有差异。在数字化时代,传统手工艺类非物质文化遗产的传承和保护面临新的挑战与机遇。中英两国在此领域的发展经验,有助于探索新时代数字技术背景下优秀传统文化传承和创造性转化的途径。

关键词：数字化平台手工艺非遗

Genome and clonal hematopoiesis stability contrasts with immune,cfDNA,mitochondrial,and telomere length changes during short duration spaceflight

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Precision Clinical Medicine 2024年第1期7卷 1-13页

作者： J.sebastian Garcia-Medina Karolina sienkiewicz s.Anand Narayanan Eliah G.Overbey Kirill Grigorev Krista A.Ryon Marissa Burke Jacqueline Proszynski Braden Tierney Caleb M.schmidt Nuria Mencia-Trinchant Remi Klotz Veronica Ortiz Jonathan Foox Christopher Chin Deena Najjar Irina Matei Irenaeus Chan Carlos Cruchaga Ashley Kleinman JangKeun Kim Alexander Lucaci Conor Loy Omary Mzava Iwijn De Vlaminck Anvita singaraju Lynn E.Taylor Julian C.schmidt Michael A.schmidt Kelly Blease Juan Moreno Andrew Boddicker Junhua Zhao bryan Lajoie Andrew Altomare semyon Kruglyak shawn Levy Min Yu Duane C.Hassane susan M.Bailey Kelly Bolton Jaime Mateus Christopher E.Mason Department of Physiology and Biophysics Weill Cornell MedicineCornell UniversityNew YorkNY 10021USA The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine Weill Cornell MedicineNew YorkNY 10021USA Department of Immunology Weill Cornell MedicineCornell UniversityNew YorkNY 10021USA Department of stem Cell Biology and Regenerative Medicine Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90033USA space Exploration Technologies Corporation HawthomeCA 90250USA sovaris Aerospace BoulderCO 80302USA Advanced Pattern Analysis&Human Performance Group BoulderCO 80302USA Children's Cancer and Blood Foundation Laboratories Departments of Pediatrics and Cell and Developmental BiologyDrukier Institute for Children's HealthMeyer Cancer CenterWeill Cornell MedicineNew YorkNY 10021USA Meyer Cancer Center Weill Cornell MedicineNew YorkNY 10065USA Department of Nutrition and Integrative Physiology Florida State UniversityTallahasseeFL 32306USA Department of systems Engineering Colorado State UniversityFort CollinsCO 80523USA Element Biosciences San DiegoCA 10055USA Department of Environmental and Radiological Health sciences Colorado State UniversityFort CollinsCO 80523USA Cell and Molecular Biology Program Colorado State UniversityFort CollinsCO 80523USA BioAstra Inc New YorkNYUSA Washington University st Louis Oncology Division St.LouisMO 63100USA Meinig school of Biomedical Engineering Cornell UniversityIthacaNY 14853USA The Feil Family Brain and Mind Research Institute Weill Cornell MedicineNY 10021USA WorldQuant Initiative for Quantitative Prediction Weill Cornell MedicineNew YorkNY 10021USA

Background The Inspiration4(I4)mission,the first all-civilian orbital flight mission,investigated the physiological effects of short-duration spaceflight through a multi-omic *** advances,there remains much to learn about human adaptation to spaceflight's unique challenges,including microgravity,immune system perturbations,and radiation *** To provide a detailed genetics analysis of the mission,we collected dried blood spots pre-,during,and post-flight for DNA *** length was measured by quantitative PCR,while whole genome and cfDNA sequencing provided insight into genomic stability and immune adaptations.A robust bioinformatic pipeline was used for data analysis,including variant calling to assess mutational *** Telomere elongation occurred during spaceflight and shortened after return to ***-free DNA analysis revealed increased immune cell signatures *** significant clonal hematopoiesis of indeterminate potential(CHIP)or whole-genome instability was *** long-term gene expression changes across immune cells suggested cellular adaptations to the space environment persisting months *** Our findings provide valuable insights into the physiological consequences of short-duration spaceflight,with telomere dynamics and immune cell gene expression adapting to spaceflight and persisting after return to *** sequencing data will serve as a reference point for studying the early development of CHIP in astronauts,an understudied phenomenon as previous studies have focused on career *** study will serve as a reference point for future commercial and non-commercial spaceflight,low Earth orbit(LEO)missions,and deep-space exploration.

关键词： genomes clonal hematopoiesis stability immune mitochondria ribosomes spaceflight

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横琴国际金融中心中国珠海

世界建筑导报 2022年第2期37卷 44-47页

作者：温子先纪达夫无 Terrence Zhang(摄影) 全球设计 CreatAR Images 不详

珠澳第一高楼,以蛟龙出海打造中国新力量“有如蛟龙卷沧海,怒气直欲山前吞。”一座339米高的建筑毗邻珠江与南海的交汇口岸,蜿蜒盘旋拔地而起,塔楼一分为四,犹如四条蛟龙冲破藩篱,直冲云霄,盘旋升腾间,俯视整片水域。这座将“蛟龙出海... 详细信息

珠澳第一高楼,以蛟龙出海打造中国新力量“有如蛟龙卷沧海,怒气直欲山前吞。”一座339米高的建筑毗邻珠江与南海的交汇口岸,蜿蜒盘旋拔地而起,塔楼一分为四,犹如四条蛟龙冲破藩篱,直冲云霄,盘旋升腾间,俯视整片水域。这座将“蛟龙出海”的神话场景完美再现的超高层,正是Aedas最新打造的珠海横琴国际金融中心。

关键词：国际金融中心直冲云霄中国珠海超高层珠海横琴出海

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流感小简史

海外英语 2009年第11期 43-43页

作者： bryan WALsH 杨明

连续数日的高热、发冷以及倦怠无力——这是流感的典型症状一而流感病毒在每个世纪都会发生几次根本性的变异，从而引发大规模的流行性疾病，健康专家也由此担心甲流同样会重蹈覆辙：

关键词：流感病毒简史根本性性疾病

复合性状转基因大豆(3Ф5423×40-3-2)喂养sD大鼠90天的亚慢性毒理学研究

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农业生物技术学报 2013年第12期50卷 1541-1541页

作者：祁潇哲贺晓云罗云波李双英邹世颖曹思硕唐茂芝 bryan Delaney 许文涛黄昆仑宋欢高婧 [a] College of Food science and Nutritional Engineering China Agricultural University Beijing China [b] The supervision Inspection and Testing Center of Genetically Modified Organisms Ministry of Agriculture Beijing China [c] Certification and Accreditation Technology Institute Certification and Accreditation Administration of People’s Republic of China Beijing China [d] Pioneer A DuPont Company Johnston IA 50021 USA

非转基因大豆油含有高浓度有益于人体健康的不饱和脂肪酸——亚油酸(18:2)和亚麻酸(18:3),但其不稳定的构象易使大豆油氧化酸败。多不饱和脂肪酸碳碳双键氢化会产生较为稳定的单不饱和脂肪(即油酸,18∶1)和饱和脂肪(即硬脂酸,18∶0)。... 详细信息

非转基因大豆油含有高浓度有益于人体健康的不饱和脂肪酸——亚油酸(18:2)和亚麻酸(18:3),但其不稳定的构象易使大豆油氧化酸败。多不饱和脂肪酸碳碳双键氢化会产生较为稳定的单不饱和脂肪(即油酸,18∶1)和饱和脂肪(即硬脂酸,18∶0)。因此工业上开发了化工和酶法等工艺生产氢化大豆油。然而氢化过程会在不同位置发生不完全饱和导致副产物反式脂肪酸的产生,不利于身体健康。为了不产生反式脂肪酸,利用转基因方法,将FAD2-1基因插入大豆中,使大豆的omega-6的脱氢酶在转录过程中沉默,

关键词：大豆转基因基因转移高油酸大鼠 sD

肠道微生物在阻塞性睡眠呼吸暂停引起的高血压中的作用

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中华高血压杂志 2015年第12期23卷 1199-1199页

作者： Durgan DJ Ganesh BP Cope JL Ajami NJ Phillips sC Petrosino JF Hollister EB bryan RM 刘莉

阻塞性睡眠呼吸暂停（obstructivesleepapnea，osA）患者是高血压高发人群。健康的肠道菌群的重要性，以及微生物紊乱对宿主生理的不利影响日益显著。研究人员观察肠道微生态失衡对OsA人群高血压是否起作用。方法：在睡眠周期通过气管... 详细信息

阻塞性睡眠呼吸暂停（obstructivesleepapnea，osA）患者是高血压高发人群。健康的肠道菌群的重要性，以及微生物紊乱对宿主生理的不利影响日益显著。研究人员观察肠道微生态失衡对OsA人群高血压是否起作用。方法：在睡眠周期通过气管中放置气球并充气（充气10s，60次／h）制备OsA大鼠模型。

关键词：阻塞性睡眠呼吸暂停肠道微生物高血压肠道微生态失衡高发人群肠道菌群研究人员睡眠周期

盾坚还是矛利精确制导武器饱和打击背景下的美军防空和反导体系再平衡

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海陆空天惯性世界 2018年第10期 10-44页

作者：马克·冈津格布莱恩·克拉克长弓(译)

本文译自美国战略和预算评估中心（CsBA）研究报告《WINNINGTHEsALV0COMPETITION：REBALANCINGAMERICAs AIR AND MIssILE DEFENsEs）），文中图表和数据均来自原文。本刊发表此文，并不表示证实其报道或赞同其观点，仅供读者参考。

关键词：精确制导武器再平衡导体系防空美军饱和评估中心

Mobilizing Crop Biodiversity

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Molecular Plant 2020年第10期13卷 1341-1344页

作者： susan McCouch Zahra Katy Navabi Michael Abberton Noelle L.Anglin Rosa Lia Barbieri Michael Baum Kirstin Bett Helen Booker Gerald L.Brown Glenn J.bryan Luigi Cattivelli David Charest Kellye Eversole Marcelo Freitas Kioumars Ghamkhar Dario Grattipaglia Robert Henry Maria Cleria Valadares Inglis Tofazzal Islam Zakaria Kehel Paul J.Kersey Graham J.King stephen Kresovich Emily Marden sean Mayes Marie Noelle Ndjiondjiop Henry T.Nguyen samuel Rezende Paiva Roberto Papa Peter W.B.Phillips Awais Rasheed Christopher Richards Mathieu Flouard Maria Jose Amstalden sampaio Uwe scholz Paul D.shaw Brad sherman s.Evan staton Nils stein Jan svensson Mark Tester Jose Francisco Montenegro Valls Rajeev Varshney stephen Visscher Eric von Wettberg Robbie Waugh Peter Wenzl Loren H.Rieseberg Plant Breeding and Genetics School of Integrated Plant SciencesCornell UniversityIthacaNY14853USA Divseek Global Institute for Food Security110 Gymnasium PlaceUniversity of SaskatchewanSaskatoonSKS7N 0W9Canada lnternational Institute of Tropical Agriculture(IITA) PMB 5320Oyo RdIbadanNigeria International Potato Center(CIP)1895 Avenida La Molina Lima Peru 12Lima 15023Peru Embrapa Genetic Resources and Biotechnology Parque Estacjao BiologicaFinal Av W5 NorteCaixa Postal 0237270770-917-Brasilia DFBrazil International Center for Agricultural Research in the Dry Areas(I CAR DA) Station Exp.INRA-Quich.Rue Hafiane Cherkaoui.Agdal.Rabat-Instituts10111RabatMorocco Department of Plant sciences University of Saskatchewan51 Campus Dr.SaskatoonSK S7N 5A8Canada Department of Plant Agriculture University of GuelphRm 316Crop Science Bldg50 Stone Rd EGuelphON N1G 2W1Canada Genome Prairie 111 Research DriveSuite 101SaskatoonSKS7N 3R2Canada The James Hutt on Institute Errol RoadInvergowrieDundeeDD25DAUK CREA Research Centre for Genomics and Bioinformaticsvia San Protaso 302Fiorenzuola d'Arda29017Italy Genome British Columbia 400-575 West 8th AvenueVancouverBCV5Z 0C4Canada International Wheat Genome sequencing Consortium 2841 NE Marywood CtLee's SummitMO.64086USA Forage science Grasslands Research CentreAgResearchPalmerston North4410New Zealand Queensla nd Alliance for Agriculture and Food Inn ovation University of QueenslandBrisbaneQLD 4072Australia Institute of Biotechnology and Genetic Engineering(IBGE) Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur 1706Bangladesh southern Cross University PO Box 157LismoreNSW 2480Australia Royal Botanic Gardens KewRichmondSurreyTW93AEUK Feed the Future Innovation Lab for Crop Improvement 431 Weill HallCornell UniversityIthacaNY14853USA Department of Botany and Biodiversity Research Centre University of British ColumbiaVancouverBC V6R 2A5Canada Crops For the Future(UK)CIC 76-80 Baddow Road ChelmsfordEs

Over the past 70 years,the world has witnessed extraordinary growth in crop productivity,enabled by a suite of technological advances,including higher yielding crop varieties,improved farm management,synthetic agrochemicals,and agricultural *** this"Green Revolution"intensified crop production,and is credited with reducing famine and malnutrition,its benefits were accompanied by several undesirable collateral effects(Pingali,2012).These include a narrowing of agricultural biodiversity,stemming from increased monoculture and greater reliance on a smaller number of crops and crop varieties for the majority of our *** reduction in diversity has created vulnerabilities to pest and disease epidemics,climate variation,and ultimately to human health(Harlan,1972).

关键词： intensified crops agricultural

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宫内生长发育迟滞新生儿主动脉壁厚度的研究

世界核心医学期刊文摘（儿科学分册） 2005年第10期1卷 9-9页

作者： skilton M.R. Evans N. griffiths K.A. D.s. Celermajer 张振 Department o f Medicine University of Sydney Sydney NSW Australia Dr.

Much epidemiological evidence has linked low birthweight with late cardiovascu lar risk. We measured aortic wall thickness (a marker of early atherosclerosis) by ultrasonography in 25 newborn babies with intrauterine growth restriction and 25 with normal birthweight. Maximum aortic thicknesses were significantly highe r in the babies with intrauterine growth restriction (810 μm [sD 113]) than in those without (743 μm [76], p=0.02), more so after adjustment for birthweight ( 300 μm/kg [45] vs 199 μm/kg [29], ps with growth restri ction have significant aortic thickening, suggesting that prenatal events might predispose to later cardiovascular risk.

关键词：主动脉壁生长发育正常出生体重出生后心血管疾病流行病学调查围生期超声扫描