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宫内生长发育迟滞新生儿主动脉壁厚度的研究

Aortic wall thickness in newborns with intrauterine growth restriction

作     者:Skilton M.R. Evans N. Griffiths K.A. D.S. Celermajer 张振 

作者机构:Department o f Medicine University of Sydney Sydney NSW Australia Dr. 

出 版 物:《世界核心医学期刊文摘(儿科学分册)》 (Dkgest of the World Latest Medical Information)

年 卷 期:2005年第1卷第10期

页      面:9-9页

学科分类:1002[医学-临床医学] 100202[医学-儿科学] 10[医学] 

主  题:主动脉壁 生长发育 正常出生体重 出生后 心血管疾病 流行病学调查 围生期 超声扫描 

摘      要:Much epidemiological evidence has linked low birthweight with late cardiovascu lar risk. We measured aortic wall thickness (a marker of early atherosclerosis) by ultrasonography in 25 newborn babies with intrauterine growth restriction and 25 with normal birthweight. Maximum aortic thicknesses were significantly highe r in the babies with intrauterine growth restriction (810 μm [SD 113]) than in those without (743 μm [76], p=0.02), more so after adjustment for birthweight ( 300 μm/kg [45] vs 199 μm/kg [29], p0.0001). Newborn babies with growth restri ction have significant aortic thickening, suggesting that prenatal events might predispose to later cardiovascular risk.

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