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I'LL HAVE A NEW BODY(I'LL HAVE A NEW LIFE)China's Cosmetic Surgery Boom

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城市漫步（GBA版） 2019年第8期 36-45页

作者： bryan Grogan 不详

The numbers don't lie;the beauty industry in China is rising *** demand for skincare products,makeup and surgical procedures grow,so are local entrepreneurs and corporations striving to nab a chunk of the *** this year,Japanese media outlet Nikkei Asian Review made the statement that beauty has become the new buzzword in the tech world,and it is certainly hard to disagree with that *** other industries,like the manufacturing,automobile and tech sectors,have been slowing,the Chinese beauty market is booming,with a multitude of factors feeding its growth.

关键词： corporation Surgery statement

Dual pH and microbial-sensitive galactosylated polymeric nanocargoes for multi-level targeting to combat ulcerative colitis

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Asian Journal of Pharmaceutical Sciences 2023年第4期18卷 124-141页

作者： Mahira Zeeshan Qurat Ul Ain Benno Weigmann Darren Story bryan R.Smith Hussain Ali Department of Pharmacy Faculty of Biological SciencesQuaid-i-Azam UniversityIslamabad 45320Pakistan Department of Medicine 1 University of Erlangen-NurembergKussmaul Campus for Medical ResearchErlangen 91052Germany Biomedical Engineering Department Michigan State UniversityEast Lansing 48824USA Institute for Quantitative Health Science and Engineering Michigan State UniversityEast Lansing 48824USA Faculty of Pharmacy Capital University of Science and TechnologyIslamabad 44000Pakistan

Ulcerative colitis(UC)is a type of inflammatory bowel disease characterized by inflammation,ulcers and irritation of the mucosal *** drug delivery in UC encounters challenges because of multifaceted ***-loaded galactosylated-PLGA/Eudragit S100/pullulan nanocargoes(Dexa-GP/ES/Pu NCs)have been developed with a dual stimuli-sensitive coating responsive to both colonic pH and microbiota,and an underneath galactosylated-PLGA core(GP).The galactose ligand of the GP preferentially binds to the macrophage galactose type-lectin-C(MGL-2)surface ***,both stimuli and ligand-mediated targeting facilitate nanocargoes to deliver Dexa specifically to the colon with enhanced macrophage *** emulsion method coupled with a solvent evaporation coating technique was employed to prepare Dexa-GP/ES/Pu *** nanocargoes were tested using in vitro,ex vivo techniques and dextran sodium sulfate(DSS)induced UC *** nanocargoes had desired physicochemical properties,drug release,cell uptake and cellular *** using a DSS-colitis model showed high localization and mitigation of colitis with downregulation of NF-ĸB and COX-2,and restoration of clinical,histopathological,biochemical indices,antioxidant balance,microbial alterations,FTIR spectra,and epithelial junctions’***,Dexa-GP/ES/Pu NCs found to be biocompatible nanocargoes capable of delivering drugs to the inflamed colon with unique targeting properties for prolonged duration.

关键词： Galactosylated nanocargoes pH-sensitive drug delivery Pullulan Microbial sensitive Ulcerative colitis Macrophage galactose type-lectin C

Pre-hospital assessment with ultrasound in emergencies: implementation in the field

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World Journal of Emergency Medicine 2016年第2期7卷 117-123页

作者： Kevin P. Rooney Sari Lahham Shadi Lahham Craig L. Anderson bryan Bledsoe bryan Sloane Linda Joseph Megan B. Osborn John C. Fox Department of Emergency Medicine Henry Ford Hospital Detroit Michigan 48202 USA Emergency Medicine University of California Irvine Orange California 92868 USA Emergency Medicine University of Nevada School of Medicine Las Vegas Nevada 89102 USA

BACKGROUND: Point-of-care ultrasound(US) is a proven diagnostic imaging tool in the emergency department(ED). Modern US devices are now more compact, affordable and portable, which has led to increased usage in austere environments. However, studies supporting the use of US in the prehospital setting are limited. The primary outcome of this pilot study was to determine if paramedics could perform cardiac ultrasound in the fi eld and obtain images that were adequate for interpretation. A secondary outcome was whether paramedics could correctly identify cardiac activity or the lack thereof in cardiac arrest ***: We performed a prospective educational study using a convenience sample of professional paramedics without ultrasound experience. Eligible paramedics participated in a 3-hour session on point-of-care US. The paramedics then used US during emergency calls and saved the scans for possible cardiac complaints including: chest pain, dyspnea, loss of consciousness, trauma, or cardiac ***: Four paramedics from two distinct fire stations enrolled a total of 19 unique patients, of whom 17 were deemed adequate for clinical decision making(89%, 95%CI 67%–99%). Paramedics accurately recorded 17 cases of cardiac activity(100%, 95%CI 84%–100%) and 2 cases of cardiac standstill(100%, 95%CI 22%–100%).CONCLUSION: Our pilot study suggests that with minimal training, paramedics can use US to obtain cardiac images that are adequate for interpretation and diagnose cardiac standstill. Further large-scale clinical trials are needed to determine if prehospital US can be used to guide care for patients with cardiac complaints.

关键词： Prehospital ultrasound Cardiac ultrasound Emergency ultrasound

I’LL HAVE A NEW BODY (I’LL HAVE A NEW LIFE)

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城市漫步（上海版、英文） 2019年第8期 36-45页

作者： bryan Grogan 不详

The numbers don't lie;the beauty industry in China is rising *** demand for skin care products,make-up and surgical procedures grow,so are local entrep re neurs and corporati ons striving to nob a chunk of the pie.

关键词： beauty industry NEW

THE FUTURE SOUND OF CHINA The Conflicting Tides of Digital Streaming and Live Music

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城市漫步（上海版、英文） 2020年第2期 36-45页

作者： bryan Grogan 不详

Consumption of digital music in China is growing *** site Tencent Music claims to have reached 800 million users,while Netease puts its number of users at around the 600 million *** have raised huge sums of funding in the past few years,helping to drive consumption of music in digital *** what does this mean for the live music industry?As more promoters,festivals and live music venues enter the fray,along with increasing investment from the government,it has become more and more obvious that the number of Chinese music fans willing to head to live shows is not rising nearly as fast as investment into the live music market might suppose.

关键词： Streaming Music users

Internal Pressure Sculpting and Speleogenesis in Autogenic Karst

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Journal of Earth Science and Engineering 2013年第7期3卷 461-476页

作者： bryan Booth Karst Research Group University of South Florida Tampa 33612 Florida USA

Understanding the ongoing speleogenic processes that produce sinkholes and control the vital drinking water supplies of Florida and much else of the world is necessary research. This article （and the associated poster presentation） discusses theoretical processes that may act in addition to mass dissolution kinetics in producing voids, conduits and caves in autogenic karst landforms. Possible theoretical factors that affect these speleogenic processes are： microscopic mixing corrosion （low constant flow, low constant flow against current, temperature-induced mixing corrosion, and pressure-induced mixing corrosion in karst matrix）, random dissolution models, simulation of gravity-induced microscopic breakdown, and storm surge effects. Finally, a theoretical model is discussed that unifies these various microscopic processes into a macro-scale process, called internal pressure sculpting. Computer models were designed to illustrate these theoretical processes： Non-calibrated computer models simulating each process discussed in this paper are presented for illustration, as well as the preliminary results of calibrated models depicting random dissolution, mechanical breakdown, and storm surge effects. The theoretical processes discussed and simulated may have major effects on cave morphology. Computer simulations appear to accurately portray the shape and form of some cave features with dissolutional morphologies. Theoretical discussion concludes with a general discussion of possible improvements to the presented models as well as the ability to generalize theoretical processes to hypogenic, halogenic, and autogenic speleogenesis.

关键词： Cave development in limestone mixing corrosion karst computer modeling solutional widening rate speleogenesis.

Hierarchical Linear Modeling in International Marketing Research： A Review with an Application on Innovation and Export in China

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Frontiers of Business Research in China 2015年第2期9卷 135-160页

作者： Kiaohui Yuan Ziliang Deng Ruer-Jer bryan Jean Daekwan Kim School of Business Renmin University of China Beijing 100872 China Department of International Business National Chengchi University Taipei 11605 TaiwanChina College of Business Florida State University Tallahassee FL 32306-1110 USA

While much of international marketing research involves two or more levels, limited work in the international marketing literature uses hierarchical linear modeling to examine different level effects. This study conducts a thorough literature review on hierarchical linear modeling （HLM） in 28 international marketing papers that employed HLM from 2005-2014 and evaluates the use of HLM in these papers on the objects, operating levels, and other issues. We call for more applications of HLM in international marketing research, particularly for research on emerging markets with significant sub-national and institutional variations. The paper provides an illustrative empirical study that employs HLM to test the moderating role of industry-level government subsidies in the relationship between firm innovation and exporter performance in China.

关键词： hierarchical linear modeling (HLM), multilevel modeling,international marketing, China, innovation export subsidy

THE FUTURE SOUND OF CHINA The Conflicting Tides of Digital Streaming and Live Music

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城市漫步（GBA版） 2020年第2期 36-45页

作者： bryan Grogan 不详

关键词： Streaming Music raised

Spatiotemporal microRNA profile in peripheral nerve regeneration:miR-138 targets vimentin and inhibits Schwann cell migration and proliferation

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Neural Regeneration Research 2018年第7期13卷 1253-1262页

作者： Travis B.Sullivan Litchfield C.Robert Patrick A.Teebagy Shannon E.Morgan Evan W.Beatty bryan J.Cicuto Peter K.Nowd Kimberly M.Rieger-Christ David J.bryan Department of Translational Research Lahey Hospital & Medical Center Tissue Engineering Laboratory Lahey Hospital & Medical Center Department of Plastic and Reconstructive Surgery Lahey Hospital & Medical Center

While the peripheral nervous system has regenerative ability,restoration of sufficient function remains a *** has been shown to be localized in axonal growth fronts and associated with nerve regeneration,including myelination,neuroplasticity,kinase signaling in nerve axoplasm,and cell migration;however,the mechanisms regulating its expression within Schwann cell（SC） remain *** aim of this study was to profile the spatial and temporal expression profile of micro RNA（mi RNA） in a regenerating rat sciatic nerve after transection,and explore the potential role of mi R-138-5 p targeting vimentin in SC proliferation and migration.A rat sciatic nerve transection model,utilizing a polyethylene nerve guide,was used to investigate mi RNA expression at 7,14,30,60,and 90 days during nerve *** levels of mi RNA expression were determined using microarray analysis and subsequently validated with quantitative real-time polymerase chain *** vitro assays were conducted with cultured Schwann cells transfected with mi RNA mimics and assessed for migratory and proliferative *** top seven dysregulated mi RNAs reported in this study have been implicated in cell migration elsewhere,and GO and KEGG analyses predicted activities essential to wound *** of one of these,mi RNA-138-5 p,into SCs reduced cell migration and *** R-138-5 p has been shown to directly target vimentin in cancer cells,and the luciferase assay performed here in rat Schwann cells confirmed *** results detail a role of mi R-138-5 p in rat peripheral nerve regeneration and expand on reports of it as an important regulator in the peripheral nervous system.

关键词： non-coding RNA neural regeneration nerve guide sciatic nerve transection peripheral nerve injury wound healing Gene Ontology processes Kyoto Encyclopedia of Genes and Genomes pathways microarray luciferase assay