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Diagnosis and m.nagem.nt of ureteral com.lications following renal transplantation

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Asian Journal of Urology 2015年第4期2卷 202-207页

作者： brian D.Duty John m.Barry Departm.nt of Urology Oregon Health&Science UniversityPortlandORUSA Departm.nt of Surgery Division of Abdominal Organ TransplantationOregon Health&Science UniversityPortlandORUSA

When com.ared with m.intenance dialysis,renal transplantation affords patients with end-stage renal disease better long-term.survival and a better quality of *** 9% of patients will develop a m.jor urologic com.lication following kidney *** com.lications are m.st com.on and include obstruction(intrinsic and extrinsic),urine leak and vesicoureteral *** anastom.tic strictures result from.technical error or ureteral *** dilation or endoureterotom. m.y be considered for short,low-grade strictures,but open reconstruction is associated with higher success *** leak usually occurs in the early postoperative *** 60% of patients can be successfully m.naged with a pelvic drain and urinary decom.ression(nephrostom. tube,ureteral stent,and indwelling bladder catheter).Proxim.l,large-volum.,or leaks that persist despite urinary diversion,require open *** reflux is com.on following *** with recurrent pyelonephritis despite antim.crobial prophylaxis require surgical *** injection m.y be considered in recipients with low-grade *** IV and V reflux are best m.naged with open reconstruction.

关键词： Renal transplantation Ureteral stricture Ureteral obstruction Urine leak Vesicoureteral reflux

A field study of a roof bolter canopy air curtain(2nd generation)for respirable coal m.ne dust control

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International Journal of m.ning Science and Technology 2019年第5期29卷 711-720页

作者： W.R.reed S.Klim. m.Shahan G.J.H.Ross K.Singh R.Cross T.Grounds CDC NIOSH Pittsburgh Mining Research DivisionPittsburghPA 15236USA Fletcher&Co. HuntingtonWV 25705USA Prairie State Generating Com.any LLC Lively GroveIL 62257USA

A 2nd generation roof bolter canopy air curtain(CAC)design was tested by National Institute for Occupational Safety and Health(NIOSH)at a m.dwestern underground coal *** the study,the roof bolter never operated downwind of the continuous *** a com.ination of personal Data Ram.(pDR)and gravim.tric sam.lers,the dust control efficiency of the roof bolter CAC was *** evaluation was determ.ned using three m.thods:(1)com.aring roof bolter operator concentrations underneath the CAC to roof bolter concentrations outside the CAC,(2)com.aring roof bolter operator concentrations underneath the CAC to the concentrations at the rear of the bolter,and finally,(3)using the gravim.tric data directly underneath the CAC to correct roof bolter operator concentrations underneath the CAC and com.aring them.to the concentrations at the rear of the *** 1 dust control efficiencies ranged from.53.9%to 60.4%.m.thod 2 efficiencies ranged from.150.5%to 52.2%,and m.thod 3 efficiencies ranged from.40.7%to 91%.Reasons for negative and low dust control efficiencies are provided in this paper and include:incorrect sam.ling locations,large distance between CAC and operator,and contam.nation of intake air from.line *** dust concentrations encountered during the testing m.de it difficult to discern whether differences in concentrations were due to the CAC or due to variances inherent in experim.ntal dust ***,the analyses,especially the m.thod 3 analysis,show that the CAC can be an effective dust control device.

关键词： Coal Roof bolter Respirable dust Underground m.ning

为诗歌配曲:论A.J.卡罗瑟斯的诗歌《迈克尔·德兰斯菲尔德之后的音乐》（英文）

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外国文学研究 2017年第3期39卷 7-15页

作者：布赖恩.里德美国华盛顿大学

作为书面艺术品的诗歌与用于表演的诗歌,即:高声朗读、背诵或歌唱的诗歌之间的关系是什么?通常情况下,以书面形式出现的诗歌可被想象为口头表演的乐曲;书面诗歌提供了词、中断、空格和其他提示信息以方便读者以可被听到的言语行为的方... 详细信息

作为书面艺术品的诗歌与用于表演的诗歌,即:高声朗读、背诵或歌唱的诗歌之间的关系是什么?通常情况下,以书面形式出现的诗歌可被想象为口头表演的乐曲;书面诗歌提供了词、中断、空格和其他提示信息以方便读者以可被听到的言语行为的方式表现诗歌。亚裔澳大利亚诗人A.J.卡罗瑟斯近期正在探索这一尚未被他人提及的设想,即:书面诗歌可被视为表演的乐曲。在《迈克尔·德兰斯菲尔德之后的音乐》一诗中,卡罗瑟斯为我们呈现了德兰斯菲尔德创作的一首简短、印刷不规则、网格状呈现的抒情诗,该诗最早发表于1978年出版的诗集《走向孤独的旅程》中。卡罗瑟斯重写了此诗给它加上了音乐符号,用曲线或弧线标记跨越几个音高的滑奏部。本文旨在通过对卡罗瑟斯配曲、演奏和表演等方面的强调激发读者对写作即是表演和页面即是写作表演舞台这一观点的思考。卡罗瑟斯提出诗歌的音乐何时、何地发生的问题,并对诗歌书面文本的原初性和表演版本的从属性或衍生性提出了质疑。最后,卡罗瑟斯发出了诗人是否和以何种方式重新演绎前人作品和民族传统或如何为它们重新配乐的疑问,重新配乐则意味着新诗的创作。

关键词： A.J.卡罗瑟斯诗歌表演书面文本

From.biom.m.cry to bioelectronics:Sm.rt m.terials for cardiac tissue engineering

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Nano Research 2020年第5期13卷 1253-1267页

作者： Olurotim. A.Bolonduro Breanna m.Duffy Akshita A.Rao Lauren D.Black brian P.Tim.o Departm.nt of Biom.dical Engineering Tufts UniversityMedfordMassachusetts 02155USA Departm.nt of Cell Molecular&Developmental BiologySchool of Graduate Biomedical SciencesTufts UniversityMassachusetts 02111USA

Effective strategies in cardiac tissue engineering require m.trices that recapitulate the m.chanical,topographic and electrical cues present in the native extracellular *** this review,we discuss recent efforts in m.terials science and nanotechnology to achieve functional three-dim.nsional(3D)scaffolds that m.dulate and m.nitor cardiac tissue *** consider key design considerations,including choice of biopolym.r m.trix,cell sources,and delivery m.thods for eventual *** then discuss how solid-state nanom.terials m.y be integrated within these system. to provide unique electrical and nanotopographic cues that im.rove electrom.chanical *** describe how these approaches m.y be extended to com.lex,spatially heterogeneous constructs using 3D bioprinting ***,we describe how scaffold m.terials m.y be augm.nted with bioelectronic com.onents to achieve hybrid m.ocardium.that m.nitors or controls electrophysiological ***,these approaches provide a fram.work for achieving cardiac tissues with tunable,rationally-designed *** discuss future prospects and rem.ining challenges for clinical translation.

关键词： cardiac tissue engineering extracellular m.trix nanom.terial bioelectronics cyborg

m.nagem.nt Procedures for Data Collected via Intelligent Transportation System.

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Journal of Civil Engineering and Architecture 2015年第9期9卷 1069-1078页

作者： Qiang Hong Richard Wallace Eric Dennis brian reed William.Tansil m.tt Sm.th Center for Autom.tive Research Ann Arbor 48108 USA Geospatial & Applied Technologies Group Parson Brinckerhoff Baltimore 21201 USA m.chigan Departm.nt of Transportation Lansing 30050 USA

Addressing transportation planning, operation and investm.nt challenges requires increasingly sophisticated data and inform.tion m.nagem.nt strategies. ITS （intelligent transportation system.） and CV （connected vehicle） technologies represent a new approach to capturing and using needed transportation data in real tim. or near real tim.. In the case of m.chigan, several ITS program. have been launched successfully, but independently of each other. The objective of this research is to evaluate and assess all im.ortant factors that will influence the collection, m.nagem.nt and use of ITS data, and recom.end strategies to develop integrated, dynam.c and adaptive data m.nagem.nt system. for state transportation agencies.

关键词： ITS connected vehicle technology transportation data m.nagem.nt state transportation agency.

Pink1 Rescues Gal4-Induced Developm.ntal Defects in the DrosophilaEye

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Advances in Parkinson's Disease 2015年第3期4卷 43-48页

作者： Am. m. Todd brian E. Staveley Departm.nt of Biology Memorial University of Newfoundland St. John’s Canada

Parkinson disease pathology often includes the presence of ubiquitin-positive, α-synuclein-enriched inclusions in the rem.ining neurons. Pink1 (also identified as PARK6) encodes a serinethreonine kinase involved in m.tochondrial protection that works with parkin to ubiquitinate various proteins, prom.ting m.tophagy. The parkin protein works to tag cystolic proteins for degradation, and previous work in our laboratory has shown the ability of parkin to rescue a Gal4-induced phenotype. To further investigate the role of Pink1 in protection against toxic proteins, we have perform.d expression studies to determ.ne the effects of increases and decreases in Pink1 on the Gal4-induced phenotype consisting of developm.ntal defects in the Drosophila eye. Our results show that Pink1 is able to rescue the Gal4-induced phenotype, highlighting a protective role for Pink1 against toxic proteins. When expressing low levels of Gal4, reductions in Pink1 or parkin are not able to induce a phenotype. This suggests that Pink1 or parkin m.y counter Gal4 effects despite reductions, or that the effects of low level Gal4 m.y be alleviated by an alternative m.chanism. m.reover, the Pink1 m.chanism.of action during differing types of cell stress, including degradation of toxic proteins, warrants further investigation.

关键词： Drosophila m.lanogaster Pink1 Parkin Gal4 Toxic Protein Parkinson Disease

Pink1 and parkindem.nstrate m.ltifaceted roles when co-expressed with Foxo

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Advances in Parkinson's Disease 2013年第1期2卷 5-10页

作者： Am. m. Todd brian E. Staveley Departm.nt of Biology Memorial University of Newfoundland St. John’s Canada

Pink1 has been linked to both autosom.l recessive and sporadic form. of Parkinson disease. The Pink1 protein is thought to be involved in m.tochondrial protection by interacting with parkin to prevent oxidative dam.ge, m.intain m.tochondrial integrity and regulate m.tophagy. Pink1 and parkin have been linked to com.onents of the insulin receptor (INR) pathway, including PTEN, Akt and Foxo, but their effects in the INR pathway have been largely overlooked. To further investigate the roles of Pink1/parkin, we have perform.d co-expression studies to determ.ne the effects Pink1 and parkin on the Foxo-induced phenotype of developm.ntal defects in the Drosophila eye. We exam.ned directed expression of Pink1, parkin, Pink1 or parkin m.tants, and Pink1 or parkin interfering RNAs (RNAi) with the overexpression of Foxo in the developing eye of Drosophila. Our findings show that reduction of Pink1 suppresses the effects of Foxo overexpression, where co-overexpression with Pink1 or parkin increases the severity of the phenotype. This suggests that Pink1 and parkin are able to increase the pro-apoptotic effects of Foxo. Contrary to the view that Pink1 and parkin act exclusively as protective proteins in the cell, it is likely that the Pink1/parkin pathway is involved in aspects of cell fate decisions other than degrading toxic proteins and m.intaining m.tochondrial integrity.

关键词： Pink1 Parkin Foxo Drosophila

Tailoring the spectral response of add/drop single and m.ltiple resonators in silicon-on-insulator

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Chinese Optics Letters 2009年第4期7卷 291-295页

作者： B.Tim.tijevic G.m.shanovich A.m.chaeli O.Cohen V.m.N.Passaro J.Crnjanski G.T.reed Advanced Technology Institute University of SurreyGuildfordGU2 7XHUK (B.Timotijevic is now with CSEM SARue Jaquet-Droz 1CH-2002 NeuchatelSwitzerland) Intel Corporation Kyriat Gat 82109JerusalemIsrael Politecnico di Bari via E.Orabona 470125 BariItaly Faculty of Electrical Engineering University of BelgradeBulevar kralja Aleksandra 73b11120 BelgradeSerbia

Channel dropping waveguide filters based on single and technology are of great interest due to their com.actness m.ltiple resonators in silicon-on-insulator （SOI） and high wavelength selectivity, which is a desirable feature for photonic m.dulators, detectors, and other optically integrated com.onents in telecom.u- nication system., in particular for wavelength division m.ltiplexing （WDm. system.. Particular advantage of these filters is that they are capable of producing relatively large free spectral range （FSR） as well as narrow 3-dB bandwidth of the filter resonances. Herein we sibility of designing m.no-m.de and （nearly） polarization with the FSR in excess of 30 nm. report experim.ntal results and discuss the posindependent SOI ring and racetrack resonators

关键词： Resonators Silicon detectors Wavelength division m.ltiplexing

Increased breath ethane and pentane concentrations in currently unm.dicated patients with schizophrenia

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Open Journal of Psychiatry 2011年第1期1卷 1-7页

作者： brian m. Ross Sandeep Shah m.lcolm.Peet 不详

Schizophrenia is a com.on and debilitating m.ntal illness. The disorder is thought to be developm.ntal in origin, with oxidative stress being im.licated as possible pathophysiological m.chanism. Breath alkanes provide a non-invasive m.ans to assess oxidative stress, with ethane levels reportedly increased in m.dicated patients with schizophrenia. It is possible, however, that the psychotropic m.dications used to treat the disorder result in elevated breath ethane levels. We have therefore m.asured the concentration of ethane and pentane, m.rkers of oxidative stress, in the breath of currently unm.dicated patients with schizophrenia. Alveolar breath sam.les were collected, applied to therm.l desorption tubes, and analyzed using a com.ination of two-stage therm.l de-sorption, gas chrom.tography and m.ss spectrom.try. Com.ared to healthy controls ethane and pentane levels were found to be elevated in patients with schizophrenia, while levels of butane were norm.l. Our data support the notion that oxidative stress is increased in schizophrenia and that this is unlikely to be a consequence of antipsychotic m.dications. In addition, breath alkane analysis m.y represent a rapid and non-invasive m.ans to m.nitor oxidative stress occurring in schizophrenia.

关键词： Breath Analysis Alkane Schizophrenia Ethane Pentane