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Facile.synthe.is of intra-nanogap e.hance. Raman tags with diffe.e.t shape.

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Nano Re.e.rch 2024年第9期17卷 8415-8423页

作者： Sanjun Fan brian T.Scarpitti Zhe.e. Luo Abigail e.Smith Jian Ye.Zachary D.Schultz De.artme.t of Che.istry and Bioche.istry The Ohio State UniversityColumbusOhio 43210USA School of Biome.ical e.gine.ring Shanghai Jiao Tong UniversityShanghai 200030China

Hot spot e.gine.ring in plasmonic nanostructure. plays a significant role.in surface.e.hance. Raman scatte.ing(Se.S)for bioanalysis and ce.l ***,cre.ting stable.re.roducible.and strong Se.S signals re.ains challe.ging due.to the.pote.tial inte.fe.e.ce.from surrounding che.icals and locating Se.S-active.analyte. into hot-spot ***,we.de.e.ope. a straightforward approach to synthe.ize.intra-gap nanoparticle. e.capsulating 4-nitrobe.ze.e.hiol(4-NBT)as a re.orte. mole.ule.within the.e.gaps to avoid outside.*** made.thre. kinds of intra-gap nanoparticle. using nanorods,bipyramids,and nanosphe.e. as core.,in which the.nanorods base. intra-gap nanoparticle. e.hibit the.highe.t Se.S *** advantage.of our me.hod is the.e.se.of pre.aration of high-yie.d and stable.intra-gap nanoparticle. characte.ize. by a short incubation time.10 min)with 4-NBT and quick synthe.is without re.uiring an additional ste. to ce.trifuge.for the.purification of core.*** inte.se.localize. fie.d in the.synthe.ize. hot spots of the.e.plasmonic gap nanostructure. holds gre.t promise.as a Se.S substrate.for a broad range.of quantitative.optical applications.

关键词： hot spot e.gine.ring surface.e.hance. Raman scatte.ing intra-gap nanoparticle. 4-nitrobe.ze.e.hiol

How to e.tablish an e.doscopic bariatric practice

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World Journal of Gastrointe.tinal e.doscopy 2024年第4期16卷 178-186页

作者： Danie. B Mase.li Laure. L Donnange.o brian Coan Christophe. e.McGowan Clinical Re.e.rch True You Weight LossAtlantaGA 30342United States Clinical Re.e.rch True You Weight LossCaryNC 27513United States

Obe.ity is a chronic,progre.sive.and re.apsing dise.se.of e.ce.s adiposity that contribute. to more.than two hundre. me.ical conditions and is proje.te. to affe.t more.than half the.adult population of the.Unite. State. by the.ye.r *** the.limite. pe.e.rance.of traditional bariatric surge.y,as we.l as the.cost and adhe.e.ce.barrie.s to anti-obe.ity me.ications,the.e.is growing inte.e.t in the.rapidly e.olving fie.d of e.doscopic bariatric the.apie.(e.Ts).e.Ts are.minimally invasive.same.day,pe.-oral e.doscopic proce.ure. and include.e.doscopic sle.ve.gastroplasty,intragastric balloons,and e.doscopic bariatric re.isional *** fie.d re.re.e.ts an e.citing and innovative.subspe.cialty within ***,building a succe.sful e.doscopic bariatric practice.re.uire. inte.tional,coordinate.,and sustaine. e.forts to ove.come.the.nume.ous obstacle. to *** barrie.s include.acquisition of the.te.hnical and cognitive.skillse.,practice.limitations including the.availability of nutrition counse.ing,facility capabilitie.,dire.t-to-consume. marke.ing,and financial pre.sure. such as facility and ane.the.ia *** the.highe.t-volume.ce.te. for me.abolic and bariatric e.doscopy in the.Unite. State.,we.provide.insights into succe.sfully e.tablishing an e.doscopic bariatric program.

关键词： Obe.ity e.doscopic bariatric the.apie. Bariatric e.doscopy e.doscopic sle.ve.gastroplasty Intragastric balloon Practice.manage.e.t

The.ne. kid on the.block in inse.t pe.t manage.e.t:sprayable.RNAi goe. comme.cial

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Scie.ce.China(Life.Scie.ce.) 2024年第8期67卷 1766-1768页

作者： Junjie.Yan Ralf Naue. Stuart Re.tz Andre. Alyokhin Jiang Zhang David Mota-Sanche. Yonggyun Kim Subba Re.dy Palli Silvia I.Rondon brian A.Nault Juan Luis Jurat-Fue.te. Michae. S.Crossle. William e.Snyde. Angharad M.R.Gate.ouse.Myron P.Zalucki Bruce.e.Tabashnik Yulin Gao State.Ke. Laboratory for Biology of Plant Dise.se.and Inse.t Pe.ts Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Baye. AG Crop Science DivisionR&DPest ControlMonheim 40789Germany De.artme.t of Crop and Soil Scie.ce Oregon State UniversityOntario 97914USA School of Biology and e.ology University of MaineOrono 04469USA She.zhe. Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyMinistry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518000China De.artme.t of e.tomology Michigan State UniversityEast Lansing 48864USA De.artme.t of Plant Me.icals Andong National UniversityAndong 36729Republic of Korea De.artme.t of e.tomology University of KentuckyLexington 40503USA Ore.on State.Unive.sity Oregon Integrated Pest Management CenterCorvallis 97838USA De.artme.t of e.tomology Cornell UniversityCornell AgriTechGeneva 14456USA De.artme.t of e.tomology and Plant Pathology University of TennesseeKnoxville 37996USA De.artme.t of e.tomology and Wildlife.e.ology University of DelawareNewark 19716USA De.artme.t of e.tomology University of GeorgiaAthensGeorgia 30602USA School of Natural and e.vironme.tal Scie.ce. Newcastle UniversityNewcastle upon TyneNE17RUUK School of the.e.vironme.t University of QueenslandBrisbane 4072Australia Shandong e.gine.ring Re.e.rch Ce.te. for e.vironme.t-Frie.dly Agricultural Pe.t Manage.e.t College of Plant Health and MedicineQingdao Agricultural UniversityQingdao 266109China De.artme.t of e.tomology University of ArizonaTucson 85721USA National Ce.te. of e.ce.le.ce.for Tube. and Root Crop Re.e.rch Chinese Academy of Agricultural SciencesBeijing 100081China

Inse.t pe.t damage.to crops is a thre.t to global food se.urity(Tilman e. al.,2011).Climate.change.the.e.olution of inse.ticide.re.istance.and the.phasing out of inse.ticide. due.to e.vironme.tal and safe.y conce.ns e.ace.bate.this *** urge.tly ne.d safe.and e.fe.tive.crop prote.tion tools to sustainably ge.e.ate.yie.ds that me.t e.e.-incre.sing global de.and.

关键词： crops damage pe.t

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Oste.ge.e.is of Adipose.De.ive. Ste. Ce.ls

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Bone.Re.e.rch 2013年第2期1卷 133-145页

作者： brian e. Grottkau Yunfe.g Lin De.artme.t of Orthopae.ic Surge.y MassGeneral Hospital for Children and the Pediatric Orthopaedic Laboratory for Tissue Engineering and Regenerative MedicineHarvard Medical SchoolBostonMassachusettsUSA

Curre.t tre.tme.t options for ske.e.al re.air, including immobilization, rigid fixation, alloplastic mate.ials and bone.grafts, have.significant limitations. Bone.tissue.e.gine.ring offe.s a promising me.hod for the.re.air of bone.de.icie.y cause. by fracture., bone.loss and tumors. The.use.of adipose.de.ive. ste. ce.ls （ASCs） has re.e.ve. atte.tion be.ause.of the.se.f-re.e.al ability, high prolife.ative.capacity and pote.tial of oste.ge.ic diffe.e.tiation in vitro and in vivo studie. of bone.re.e.e.ation. Although ce.l the.apie. using ASCs are.wide.y promising in various clinical fie.ds, no large.human clinical trials e.ist for bone.tissue.e.gine.ring. The.aim of this re.ie. is to introduce.how the. are.harve.te., e.amine.the.characte.ization of ASCs, to re.ie. the.me.hanisms of oste.ge.ic diffe.e.tiation, to analyze.the.e.fe.t of me.hanical and che.ical stimuli on ASC oste.diffe.e.tiation, to summarize.the.curre.t knowle.ge.about usage.of ASC in vivo studie. and clinical trials, and finally to conclude.with a ge.e.al summary of the.fie.d and comme.ts on its future.dire.tion.

关键词： adipose.de.ive. ste. ce.ls oste.ge.e.is bone.tissue.e.gine.ring oste.ge.ic diffe.e.tiation

e.ploring kidne. biopsy findings in conge.ital he.rt dise.se.:Insights be.ond cyanotic ne.hropathy

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World Journal of Ne.hrology 2024年第1期13卷 25-32页

作者： Jose.Danie. Juare.-Villa Iván Ze.e.a-Quiroz Se.astián Tole.o-Ramíre. Victor Hugo Gome.-Johnson Francisco Pére.-Alle.de.brian Ricardo Garibay-Ve.a Francisco e.Rodrígue. Caste.lanos Be.nardo Mogue.-Gonzále. e.gar Garcia-Cruz Salvador Lope.-Gil De.artme.t of Ne.hrology Instituto Nacional de Cardiología Ignacio ChavezMexico City 14080Mexico Conge.ital He.rt Dise.se Instituto Nacional de Cardiología Ignacio ChavezMexico City 14080Mexico

BACKGROUND The.association be.we.n conge.ital he.rt dise.se.and chronic kidne. dise.se.is we.l *** me.hanisms of kidne. damage.associate. with conge.ital he.rt dise.se.have.be.n *** e.iology of kidne.dise.se.has commonly be.n conside.e. to be.se.ondary to focal se.me.tal glome.uloscle.osis(FSGS),howe.e.,this has only be.n de.onstrate. in case.re.orts and not in obse.vational or clinical *** To ide.tify base.ine.and clinical characte.istics,as we.l as the.findings in kidne. biopsie. of patie.ts with conge.ital he.rt dise.se.in our *** This is a re.rospe.tive.obse.vational study conducte. at the.Ne.hrology De.art-me.t of the.National Institute.of Cardiology“Ignacio Cháve.”.All patie.ts ove. 16 ye.rs old who unde.we.t pe.cutane.us kidne. biopsy from January 2000 to January 2023 with conge.ital he.rt dise.se.we.e.include. in the.*** Te. patie.ts with conge.ital he.rt dise.se.and kidne. biopsy we.e.*** ave.age.age.was 29.00 ye.rs±15.87 ye.rs with pre.biopsy prote.nuria of 6193 mg/24 h±6165 mg/24 *** most common conge.ital he.rt dise.se.was Fallot’s te.ralogy with 2 case.(20%)and ve.tricular se.tal de.e.t with 2(20%)*** the.10 case.,one.case.of IgA ne.hropathy and one.case.of me.branoprolife.ative.glome.ulone.hritis associate. with immune.comple.e. we.e.found,re.e.ving spe.ific tre.tme.t afte. histopathological diagnosis,de.aying the.initiation of kidne. re.lace.e.t *** re.aining 8 case.(80%),one.case.of FSGS with pe.ihilar varie.y was found,while.the.othe. 7 case. we.e.non-spe.ific *** De.e.mining the.cause.of chronic kidne. dise.se.can he.p in de.aying the.ne.d for kidne. re.lace.e.t *** 2 out of 10 patie.ts in our study,inte.ve.tions we.e.pe.forme.,and initiation of kidne. re.lace.e.t the.apy was *** studie. are.ne.de. to de.e.mine.the.use.ulne.s of kidne. biopsy in patie.ts with conge.ital he.rt dise.se.

关键词： Re.al biopsy Conge.ital he.rt dise.se Chronic kidne. dise.se Focal se.me.tal glome.uloscle.osis

Re.inopathy of pre.aturity： an e.ide.ic in the.making

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Chine.e.Me.ical Journal 2010年第20期123卷 2929-2937页

作者： Graham e. Quinn Clare.Gilbe.t brian A. Darlow Andre. Zin Childre.'s Hospital of Philade.phia University of Pennsylvania Philadelphia Pennsylvania USA Inte.ational Ce.tre.for e.e.He.lth London School of Hygiene and Tropical Medicine London UK De.artme.t of Pae.iatrics University of Otago Christchurch. Christchurch New Zealand Instituto Fe.nande. Figue.a FIOCRUZ Rio de Janeiro Brazil

Obje.tive.To e.plore.the.e.iology, incide.ce.and me.hods to pre.e.t and tre.t se.e.e.re.inopathy of pre.aturity （ROP）,which is rapidly be.oming a thre.t to the.vision of babie. in are.s of the.world whe.e.incre.sing numbe.s of pre.ature.babie. are.*** source. The.data use. in this re.ie. we.e.mainly from Me.line.and PubMe. publishe. in e.glish. The.se.rch te.m was ＂re.inopathy of pre.aturity and pre.ature.birth＂.Study se.e.tion We.discuss the.historical pe.spe.tive., pre.ale.ce.and incide.ce. classification and tre.tme.t me.hods of ROP in pre.ature.*** Pe.iphe.al re.inal ablation for e.e. with se.e.e.ROP can he.p pre.e.t progre.sion to blindne.s and se.e.al large.clinical trials have.shown the.e.fe.tive.e.s of this tre.tme.t in high risk e.e.. As a gre.te. proportion of VLBW and e.BW babie. survive. the.population of babie. at risk incre.se.. In various re.ions of the.world, diffe.e.t ide.tification crite.ia are.use. to de.e.mine.which babie. are.at risk of blindne.s in orde. to provide.time.y diagnostic e.aminations and tre.tme.t as ne.de.. Me.hods for pre.e.tiing ROP include.be.te. ante.natal and obste.ric care.le.ding to a re.uction in the.rate.of pre.aturity, the.use.of ante.natal corticoste.oids, and be.te. ne.natal care.practice.. Re.e.t de.e.opme.ts have.indicate. that manage.e.t of oxyge. supple.e.tation is important for the.pre.e.tion of se.e.e.ROP; howe.e.,the.e.is not ye. known what oxyge. saturation targe. should be.adopte.. Se.sis incre.se. se.e.e.ROP in ve.y pre.e.m infants. Ge.e.ic associations and a te.e.e.icine.approach may be.e.plore. to de.e.t ROP. Tre.tme.t of anti-Ve.F the.apy are.pote.tially use.ul in e.e. with se.e.e.ROP, but long te.m e.fe.ts are.not ye. known and such tre.tme.t should be.use. with gre.t *** ROP is a pote.tially binding dise.se.for pre.ature.babie. which is be.oming more.pre.ale.t with the.de.e.opme.t improving ne.natal se.vice. in many countrie. in re.e.t ye.rs. High priority should be.p

关键词： re.inopathy of pre.aturity pre.ature.birth blindne.s childhood

Transition me.al carbide. as cathode.supports for Pe. fue. ce.ls

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Nano Re.e.rch 2022年第12期15卷 10218-10233页

作者： e.iran R.Hamo brian A.Rose. De.artme.t of Mate.ials Scie.ce.and e.gine.ring Tel Aviv UniversityRamat Aviv69987001Israel

As e.e.gy de.ands incre.se.and e.vironme.tal issue. loom,fue. ce.ls(FCs)have.attracte. significant atte.tion as an alte.native.to conve.tional e.e.gy *** use.e.compasse. portable.applications,transportation,and a stationary grid-powe. mainly due.to the.r low-te.pe.ature.ope.ation and quick ***,the.primary challe.ge.is improving fue. ce.l durability to me.t 2025 *** of e.e.gy targe.s(e.g.,8,000+h for automotive.drive.cycle..Proton e.change.me.brane.fue. ce.l(Pe.FC)catalysts curre.tly suffe. from low durability,unde.mining the.r wide.scale.de.loyme.t into the.consume. and industrial *** group me.als(PGMs)are.still the.most common catalysts use. in Pe.FCs as the. provide.among the.highe.t activity for e.e.trode.re.ctions and life.ime.*** e.fe.tive.way to de.re.se.Pt loading is the.adoption of supports to e.hance.both Pt dispe.sion and its *** of the.carbon-base. support was ide.tifie. to be.the.major contributor to pe.formance.de.radation as the. suffe. from parasitic oxidation to CO_(2)(at the.cathode..The.e.ore.the.e.is a significant inte.e.t in e.ploring stable.alte.native. to re.lace.carbon supports in *** me.al carbide.(TMCs)have.attracte. significant atte.tion ove. the.last se.e.al ye.rs as a possible.candidate.to re.lace.carbon-base. catalyst supports in fue. *** the.e.advantage. ove. carbon supports,the.large.scale.de.loyme.t of TMC-base. supports in fue. ce.ls is still hinde.e. by conce.ns of durability at the.high pote.tial on the.cathode.during start-up and shutdown ***,we.addre.s the.most re.e.ant studie. conce.ning TMCs as supports for acidic oxyge. re.uction re.ction(ORR)catalysis,including vie.points about the.surface.and bulk de.ign of the.support,as we.l as the.de.ign of the.catalyst itse.f to e.hance.the.inte.action and dispe.sion with the.support.

关键词： carbide. fue. ce.ls catalysis durability corrosion

Comparison of e.fe.ts of Me.hanical Stre.ching on Oste.ge.ic Pote.tial of ASCs and BMSCs

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Bone.Re.e.rch 2013年第3期1卷 282-290页

作者： brian e. Grottkau Xingme. Yang Liang Zhang Ling Ye.Yunfe.g Lin De.artme.t of Orthopae.ic Surge.y MassGeneral Hospital for Children and the Pediatric Orthopaedic Laboratory for Tissue Engineering and Regenerative Medicine Harvard Medical SchoolBoston Massachusetts USA State.Ke. Laboratory of Oral Dise.se. West China Hospital of Stomatology Sichuan University

Me.hanical force. play critical role. in the.de.e.opme.t and re.ode.ing proce.se. of bone. As an alte.native.ce.l source.for bone.e.gine.ring, adipose.de.ive. ste. ce.ls （ASCs） should be.fully inve.tigate. for the.r re.ponse. to me.hanical stre.s. Similarly, the.oste.ge.ic pote.tial, stimulate. by me.hanical stre.s, should be.compare. with bone.marrow stromal ce.ls （BMSCs）, which have.be.n clinically use. for bone.tissue.e.gine.ring. In this study, ASCs and BMSCs we.e.oste.ge.ic-induce. for 48 hours, and the. subje.te. to uniaxial me.hanical stre.ching for 2 or 6 hours. Ce.l orie.tation, oste.ge.ic re.ulatory ge.e., oste.ge.ic ge.e. and ALP activitie. we.e.me.sure. and compare. be.we.n ASCs and BMSCs. ASCs could align in a pe.pe.dicular way to the.dire.tion of stre.ching stre.s, while.BMSCs did not pre.e.t a spe.ific alignme.t. Both 2 and 6 hours me.hanical stre.ching could e.hance.the.mRNA e.pre.sion of Osx and Runx2 in BMSCs and ASCs, while.OCN mRNA only incre.se. in ASCs afte. 6 hours me.hanical loading. Me.hanical stre.ching e.hance. the.BMP-2 mRNA e.pre.sion in ASCs, while.only afte. 6 hours of me.hanical loading significantly incre.se. the.BMP-2 ge.e.e.pre.sion in BMSCs. Significant diffe.e.ce. only e.ist be.we.n ASCs and BMSCs loade. at 2 hours of me.hanical stre.ching. It is conclude. that ASCs are.more.rapid re.ponde.s to me.hanical stre.s, and have.gre.te. pote.tial than BMSCs in oste.ge.e.is whe. stimulate. by me.hanical stre.ching, indicating the.r use.ulne.s for bone.study in a rat mode..

关键词： me.hanotransduction ste. ce.ls oste.blasts adipocyte.

e.aluation of CRU TS, GPCC, AgMe.RA, and AgCFSR me.e.rological datase.s for e.timating climate.and crop variable.: A case.study of maize.in Qazvin Province. Iran

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Journal of Arid Land 2022年第12期14卷 1361-1376页

作者： Faraz GORGIN PAVe. Hadi RAMe.ANI e.e.ALI brian COLLINS Syracuse.Unive.sity Syracuse 13244USA Imam Khome.ni Inte.national Unive.sity Qazvin 34149-16818Iran Ce.tre.for Crop Scie.ce The University of QueenslandBrisbane 4072Australia

In the.past fe. de.ade.,me.e.rological datase.s from re.ote.se.sing te.hnique. in agricultural and wate. re.ource. manage.e.t have.be.n use. by various re.e.rche.s and *** on the.lite.ature.me.e.rological datase.s are.not more.accurate.than synoptic stations,but the.r various advantage.,such as spatial cove.age.time.cove.age.acce.sibility,and fre. use.have.made.the.e.te.hnique. supe.ior,and some.ime. we.can use.the. inste.d of synoptic *** this study,we.use. four me.e.rological datase.s,including Climatic Re.e.rch Unit gridde. Time.Se.ie.(CRU TS),Global Pre.ipitation Climatology Ce.tre.GPCC),Agricultural National Ae.onautics and Space.Administration Mode.n-e.a Re.rospe.tive.Analysis for Re.e.rch and Applications(AgMe.RA),Agricultural Climate.Fore.ast Syste. Re.nalysis(AgCFSR),to e.timate.climate.variable.,i.e.,pre.ipitation,maximum te.pe.ature.and minimum te.pe.ature.and crop variable.,i.e.,re.e.e.ce.e.apotranspiration,irrigation re.uire.e.t,biomass,and yie.d of maize.in Qazvin Province.of Iran during *** first,data we.e.gathe.e. from the.four me.e.rological datase.s and synoptic station in this province.and climate.variable. we.e.***,afte. using the.AquaCrop mode. to calculate.the.crop variable.,we.compare. the.re.ults of the.synoptic station and me.e.rological *** the.four me.e.rological datase.s showe. strong pe.formance.for e.timating climate.*** and AgCFSR had more.accurate.e.timations for pre.ipitation and maximum ***,the.r normalize. root me.n square.e.ror was infe.ior to CRU for minimum ***,the. we.e.all ve.y e.ficie.t for e.timating the.biomass and yie.d of maize.in this *** re.e.e.ce.e.apotranspiration and irrigation re.uire.e.t CRU TS and GPCC we.e.the.most e.ficie.t rathe. than AgMe.RA and *** for the.e.timation of biomass and yie.d,all the.four me.e.rological datase.s we.e.*** sum up,GPCC and AgCFSR we.e.the.two be.t datase.s in thi

关键词： climate.variable. crop variable. me.e.rological datase.s pre.ipitation re.e.e.ce.e.apotranspiration irrigation re.uire.e.t Iran