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骨质疏松性骨折人群跌倒风险、骨密度、肌力和体脂的相关性

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中华骨质疏松和骨矿盐疾病杂志 2017年第1期10卷 53-57页

作者：朱秀芬彭志坚 brian lin 马大年陈新杨海明林华南京大学医学院附属鼓楼医院骨病中心南京210008 昆山市中医院医务处昆山215300 Department of Neuroscience Johns Hopkins University3400N Baltimore 江苏省盱眙县人民医院骨科盱眙211700

目的探讨骨质疏松性骨折人群的骨密度与跌倒风险、体质量指数(body mass index,BMI)、肌力、体脂含量的相关性。方法通过对4 632例社区45岁以上绝经后女性的问卷调研及骨密度筛查,筛查出既往有脆性骨折史的骨质疏松性骨折人群。测定骨... 详细信息

目的探讨骨质疏松性骨折人群的骨密度与跌倒风险、体质量指数(body mass index,BMI)、肌力、体脂含量的相关性。方法通过对4 632例社区45岁以上绝经后女性的问卷调研及骨密度筛查,筛查出既往有脆性骨折史的骨质疏松性骨折人群。测定骨质疏松性骨折人群的骨密度、身高、体质量、跌倒风险、肌力和腹部脂肪含量。采用Spearman检验分析跌倒指数、体脂含量、年龄、身高、体质量、BMI与骨密度(bone mass density,BMD)之间的相关性。BMD校正年龄、身高、体质量、BMI、体脂含量,采用ANCOVA分析跌倒指数对BMD的影响;校正年龄、身高、体质量、BMI、跌倒指数,分析体脂含量对BMD的影响。结果对筛查出的839例骨质疏松性骨折患者的BMD、BMI、跌倒风险、腹部体脂含量、肌力等相关性分析结果显示,骨质疏松性骨折人群BMI、跌倒指数、肌力与BMD均显著相关(BMI r=0.161,跌倒指数r=0.238,肌力r=0.198,P均0.05)。结论跌倒风险和低BMD为骨折的主要危险因素。本研究显示体脂含量与BMD呈显著相关性。

关键词：骨质疏松性骨折骨密度肌力跌倒风险体脂含量

设计要点采用23mm×16.5mm封装的170W倍压器

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电子产品世界 2018年第4期 51-52页

作者： Ya Liu Jian Li Jeff Zhang brian lin

引言对于高电压输入/输出应用,无电感型开关电容器转换器(充电泵)相比基于电感器的传统降压或升压拓扑可显著地改善效率和缩减解决方案尺寸。通过采用充电泵取代电感器,一个"跨接电容器"可用于存储能量和把能量从输入传递至输出。电容... 详细信息

引言对于高电压输入/输出应用,无电感型开关电容器转换器(充电泵)相比基于电感器的传统降压或升压拓扑可显著地改善效率和缩减解决方案尺寸。通过采用充电泵取代电感器,一个"跨接电容器"可用于存储能量和把能量从输入传递至输出。电容器的能量密度远高于电感器,因而采用充电泵可使功率密度提高10倍。但是,由于在启动、保护、栅极驱动和稳压方面面临挑战,所以充电泵传统上一直局限于低功率应用。LTC(?)7820克服了这些问题,可实现高功率密度、高效率(达99%)的解决方案。这款固定比例、高电压、高功率开关电容器控制器内置4个N沟道MOSFET栅

关键词：开关电容器充电泵电感器

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骨质疏松性椎体骨折可控风险因素分析

中华健康管理学杂志 2017年第4期11卷 308-313页

作者：朱秀芬何占德 brian lin 曹威陈新杨海明林华南京大学医学院附属鼓楼医院骨病中心南京210008 江苏省盱眙县中医院骨质疏松骨病中心江苏省盱眙县211700 Neuroscience Department Johns Hopkins University Baltimore 3400N United States ofAmerica

目的分析骨质疏松性椎体骨折的相关可控风险因素,提示管理可控风险因素的临床价值.方法绝经后女性626例,收集患者年龄、身高、体重、腰椎和髋部骨密度值及腹部体脂含量等信息,采用Tetrax平衡测试系统评估跌倒风险.通过胸腰段X线侧位... 详细信息

目的分析骨质疏松性椎体骨折的相关可控风险因素,提示管理可控风险因素的临床价值.方法绝经后女性626例,收集患者年龄、身高、体重、腰椎和髋部骨密度值及腹部体脂含量等信息,采用Tetrax平衡测试系统评估跌倒风险.通过胸腰段X线侧位片将患者分为椎体骨折组和无椎体骨折组,对两组临床资料进行分析比较,并采用Spearman检验,分析椎体骨折与年龄、身高、体重、体质指数（BMI）及骨密度、跌倒风险、体脂含量等可控因素的相关性.结果椎体骨折组328例,无椎体骨折组298例,骨折涉及426个椎体.椎体骨折组与无椎体骨折组比较,椎体骨折组具有年龄大[（68.67±9.29）岁比（63.04±9.30）岁]、身高矮[（151.10±4.39）cm比（154.90±5.86）cm]、骨密度低[腰椎骨密度（0.85±0.16）g/cm2比（0.93±0.17）g/cm2,全髋骨密度（0.72±0.18）g/cm2比（0.81±0.13）g/cm2]及腹部脂肪含量高[（41.30±5.20）％比（36.30±5.90）％]、跌倒风险高（41.38±25.79比36.20±26.22）的特点,差异均有统计学意义（P均〈0.001）;相关性分析显示,年龄、身高、BMI、腹部体脂含量、跌倒风险腰椎和全髋骨密度与椎体骨折显著相关,r值依次为0.358、-0.323、0.169、0.186、0.135、-0.398、-0.364（P均〈0.001）.结论骨量丢失、跌倒风险增高、腹部脂肪含量增加是绝经后女性骨质疏松性椎体压缩性骨折的重要可控风险因素.

关键词：骨质疏松性骨折骨密度体脂肪率意外跌倒

规则引擎在机场资源管理系统中的研究与应用(英文)

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江西师范大学学报（自然科学版） 2008年第2期32卷 142-147页

作者：曲守宁朱强林泊翰邹燕崔广强济南大学信息与网络中心山东济南250022 济南大学信息科学与工程学院山东济南250022 致晟科技有限公司北京100600

在机场资源管理系统(ARMS)中,存在大量灵活多变的业务规则,这大大增加了机场业务及资源的管理难度.传统的机场资源管理系统把业务规则和程序代码混杂在一起,使机场资源分配策略和业务规则不能及时改变以适应现实情况.该文引入规则引擎... 详细信息

在机场资源管理系统(ARMS)中,存在大量灵活多变的业务规则,这大大增加了机场业务及资源的管理难度.传统的机场资源管理系统把业务规则和程序代码混杂在一起,使机场资源分配策略和业务规则不能及时改变以适应现实情况.该文引入规则引擎技术的架构和运行机制,提出了将频繁变化的业务规则从系统中分离出来的必要性和可行性,并分析了基于规则引擎的机场资源管理系统的架构、设计方法,将规则独立定义到规则库中,实现了机场业务规则和系统代码的完全分离,加快了系统的开发、升级和维护过程,增强了系统的灵活性和扩展性,使机场业务人员能够根据需求灵活调整业务规则和资源分配方案,最后,总结出现有方案的优点和存在的问题.

关键词：规则引擎 Rete算法模式匹配议程工作内存

Significance of Vibrio species in the marine organic carbon cycle-A review

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Science China Earth Sciences 2018年第10期61卷 1357-1368页

作者： Xiaohua ZHANG Heyu lin Xiaolei WANG brian AUSTIN College of Marine Life Sciences Ocean University of China Qingdao 266003 China Laboratory for Marine Ecology and Environmental Science Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071 China Institute of Aquaculture University of StirlingStirling FK9 4LA UK

The genus Vibrio,belonging to Gammaproteobacteria of the phylum Proteobacteria,is a genetically and ecologically diverse group of heterotrophic bacteria,that are ubiquitous in marine environments,especially in coastal *** particular,vibrios dominate,*** to 10%of the readily culturable marine bacteria in these *** distribution of Vibrio *** shaped by various environmental parameters,notably temperature,salinity and dissolved organic *** utilize a wide range of organic carbon compounds,including chitin(this may be metabolized by most Vibrio spp.),alginic acid and *** Vibrio *** very short replication times(as short as～10 min),which could facilitate them developing into high biomass content albeit for relatively short *** *** comprise a minor portion(typically^1%of the total bacterioplankton in coastal waters)of the total microbial population,they have been shown to proliferate explosively in response to various nutrient pulses,e.g.,organic nutrients from algae blooms and iron from Saharan ***,Vibrio *** exert large impacts on marine organic carbon cycling especially in marginal *** and related areas of investigation will reveal more about the molecular components and mechanisms involved in Vibrio-mediated biotransformation and remineralization processes.

关键词： Vibrio Ecology Carbon cycle Marine Organic carbon

Osteogenesis of Adipose-Derived Stem Cells

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Bone Research 2013年第2期1卷 133-145页

作者： brian E. Grottkau Yunfeng lin Department of Orthopaedic Surgery MassGeneral Hospital for Children and the Pediatric Orthopaedic Laboratory for Tissue Engineering and Regenerative MedicineHarvard Medical SchoolBostonMassachusettsUSA

Current treatment options for skeletal repair, including immobilization, rigid fixation, alloplastic materials and bone grafts, have significant limitations. Bone tissue engineering offers a promising method for the repair of bone deficieny caused by fractures, bone loss and tumors. The use of adipose derived stem cells （ASCs） has received attention because of the self-renewal ability, high proliferative capacity and potential of osteogenic differentiation in vitro and in vivo studies of bone regeneration. Although cell therapies using ASCs are widely promising in various clinical fields, no large human clinical trials exist for bone tissue engineering. The aim of this review is to introduce how they are harvested, examine the characterization of ASCs, to review the mechanisms of osteogenic differentiation, to analyze the effect of mechanical and chemical stimuli on ASC osteodifferentiation, to summarize the current knowledge about usage of ASC in vivo studies and clinical trials, and finally to conclude with a general summary of the field and comments on its future direction.

关键词： adipose derived stem cells osteogenesis bone tissue engineering osteogenic differentiation

Scene text recognition via dual character counting-aware visual and semantic modeling network

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Science China(Information Sciences) 2024年第3期67卷 313-314页

作者： Ke XIAO Anna ZHU brian Kenji IWANA Cheng-lin LIU School of Computer Science and Artificial Intelligence Wuhan University of Technology Human Interface Laboratory Kyushu University State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of AutomationChinese Academy of Sciences School of Artificial Intelligence University of Chinese Academy of Sciences

Scene text recognition(STR) is drawing increasing attention nowadays due to its wide application in real life. Character counting information, as auxiliary information, has been shown to be effective in boosting text ... 详细信息

关键词： Decoding

Comparison of Effects of Mechanical Stretching on Osteogenic Potential of ASCs and BMSCs

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Bone Research 2013年第3期1卷 282-290页

作者： brian E. Grottkau Xingmei Yang Liang Zhang ling Ye Yunfeng lin Department of Orthopaedic Surgery MassGeneral Hospital for Children and the Pediatric Orthopaedic Laboratory for Tissue Engineering and Regenerative Medicine Harvard Medical SchoolBoston Massachusetts USA State Key Laboratory of Oral Diseases West China Hospital of Stomatology Sichuan University

Mechanical forces play critical roles in the development and remodeling processes of bone. As an alternative cell source for bone engineering, adipose-derived stem cells （ASCs） should be fully investigated for their responses to mechanical stress. Similarly, the osteogenic potential, stimulated by mechanical stress, should be compared with bone marrow stromal cells （BMSCs）, which have been clinically used for bone tissue engineering. In this study, ASCs and BMSCs were osteogenic-induced for 48 hours, and then subjected to uniaxial mechanical stretching for 2 or 6 hours. Cell orientation, osteogenic regulatory genes, osteogenic genes and ALP activities were measured and compared between ASCs and BMSCs. ASCs could align in a perpendicular way to the direction of stretching stress, while BMSCs did not present a specific alignment. Both 2 and 6 hours mechanical stretching could enhance the mRNA expression of Osx and Runx2 in BMSCs and ASCs, while OCN mRNA only increased in ASCs after 6 hours mechanical loading. Mechanical stretching enhanced the BMP-2 mRNA expression in ASCs, while only after 6 hours of mechanical loading significantly increased the BMP-2 gene expression in BMSCs. Significant differences only exist between ASCs and BMSCs loaded at 2 hours of mechanical stretching. It is concluded that ASCs are more rapid responders to mechanical stress, and have greater potential than BMSCs in osteogenesis when stimulated by mechanical stretching, indicating their usefulness for bone study in a rat model.

关键词： mechanotransduction stem cells osteoblasts adipocytes

Advances in endovascular aneurysm management: coiling and adjunctive devices

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Stroke & Vascular Neurology 2020年第1期5卷 14-21页

作者： Jessica K Campos brian V Lien Alice S Wang Li-Mei lin Department of Neurological Surgery University of California Irvine Medical CenterOrangeCaliforniaUSA College of Osteopathic Medicine of the Pacific Western University of Health SciencesPomonaCaliforniaUSA Carondelet Neurological Institute St.Joseph's HospitalCarondelet Health NetworkTucsonAZUnited States

Endovascular coil embolisation continues to evolve and remains a valid modality in managing ruptured and unruptured cerebral *** advances in coil properties,adjunctive devices and interventional techniques continue to improve long-term aneurysm occlusion *** review elaborates on the latest advances in next-generation endovascular coils and adjunctive coiling techniques for treating cerebral aneurysms.

关键词： aneurysm cerebral endovascular