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CNN-BiLSTm-Attention model in Forecasting Wave Height over South-East China Seas

Computers, materials & Continua 2022年第10期73卷 2151-2168页

作者： Lina Wang Xilin Deng Peng Ge Changming Dong brandon J.Bethel Leqing Yang Jinyue Xia School of Artificial Intelligence(School of Future Technology) Nanjing University of Information Science and Technology Nanjing210044China Southern marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai519080China School of marine Sciences Nanjing University of Information Science and TechnologyNanjing210044China International Business machines Corporation(IBm) New York10504USA

Though numerical wave models have been applied widely to significant wave height prediction,they consume massive computing memory and their accuracy needs to be further *** this paper,a two-dimensional(2D)significant wave height(SWH)prediction model is established for the South and East China *** proposed model is trained by Wave Watch III(WW3)reanalysis data based on a convolutional neural network,the bidirectional long short-term memory and the attention mechanism(CNNBiLSTm-Attention).It adopts the convolutional neural network to extract spatial features of original wave height to reduce the redundant information input into the BiLSTm ***,the BiLSTm model is applied to fully extract the features of the associated information of time series ***,the attention mechanism is used to assign probability weight to the output information of the BiLSTm layer units,and finally,a training model is *** to 24-h prediction experiments are conducted under normal and extreme conditions,*** the normal wave condition,for 3-,6-,12-and 24-h forecasting,the mean values of the correlation coefficients on the test set are 0.996,0.991,0.980,and 0.945,*** corresponding mean values of the root mean square errors are measured at 0.063 m,0.105 m,0.172 m,and 0.281 m,*** the typhoon-forced extreme condition,the model based on CNN-BiLSTm-Attention is trained by typhooninduced SWH extracted from the WW3 reanalysis *** 3-,6-,12-and 24-h forecasting,the mean values of correlation coefficients on the test set are respectively 0.993,0.983,0.958,and 0.921,and the averaged root mean square errors are 0.159 m,0.257 m,0.437 m,and 0.555 m,*** model performs better than that trained by all the WW3 reanalysis *** result suggests that the proposed algorithm can be applied to the 2D wave forecast with higher accuracy and efficiency.

关键词： Conv2D CNN-BiLSTm-Attention wave forecasting significant wave height typhoon

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Interrater Reliability Estimation via maximum Likelihood for Gwet’s Chance Agreement model

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Open Journal of Statistics 2024年第5期14卷 481-491页

作者： Alek m. Westover Tara m. Westover m. brandon Westover massachusetts Institute of Technology Boston MA USA Harvard medical School Beth Israel Deaconess Medical Center Boston MA USA

Interrater reliability (IRR) statistics, like Cohen’s kappa, measure agreement between raters beyond what is expected by chance when classifying items into categories. While Cohen’s kappa has been widely used, it has several limitations, prompting development of Gwet’s agreement statistic, an alternative “kappa”statistic which models chance agreement via an “occasional guessing” model. However, we show that Gwet’s formula for estimating the proportion of agreement due to chance is itself biased for intermediate levels of agreement, despite overcoming limitations of Cohen’s kappa at high and low agreement levels. We derive a maximum likelihood estimator for the occasional guessing model that yields an unbiased estimator of the IRR, which we call the maximum likelihood kappa (κmL). The key result is that the chance agreement probability under the occasional guessing model is simply equal to the observed rate of disagreement between raters. The κmLstatistic provides a theoretically principled approach to quantifying IRR that addresses limitations of previous κcoefficients. Given the widespread use of IRR measures, having an unbiased estimator is important for reliable inference across domains where rater judgments are analyzed.

关键词： Interrater Reliability Agreement Reliability Kappa

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Computed tomography overestimation of esophageal tumor length: Implications for radiotherapy planning

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World Journal of Gastrointestinal Oncology 2010年第4期2卷 197-204页

作者： Karim Sillah Luke R williams Hans-Ulrich Laasch Azeem Saleem Gillian Watkins Susan A Pritchard Patricia m Price Catharine m West Ian m Welch Department of Gastrointestinal Surgery University Hospital of South Manchester NHS Foundation TrustSouthmoor RoadManchester M23 9LTUnited Kingdom School of Cancer&Enabling Sciences University of ManchesterChristie HospitalWilmslow RoadManchester M20 4BXUnited Kingdom Department of Radiology University Hospital of South Manchester NHS Foundation TrustSouthmoor RoadManchester M23 9LTUnited Kingdom Department of Radiology The Christie NHS Foundation TrustWilmslow RoadManchester M20 4BXUnited Kingdom Department of Histopathology University Hospital of South Manchester NHS Foundation TrustSouthmoor RoadManchester M23 9LTUnited Kingdom

AIm:To assess the relationship between preoperative computed tomography(CT)and postoperative pathological measurements of esophageal tumor length and the prognostic significance of CT tumor length ***:A retrospective study was carried out in 56 patients who underwent curative *** lengths were measured on the immediate preoperative CT and on the post-operative resection ***-and intra-observer variations in CT measurements were *** data were ***:There was a weak correlation between CT and pathological tumor length(r=0.30,P=0.025).CT lengths were longer than pathological lengths in 68%(38/56)of patients with a mean difference of 1.67 cm(95%CI:1.18-2.97).The mean difference in measurements by two radiologists was 0.39 cm(95% CI:-0.59-1.44).The mean difference between repeat CT measured tumor length(intra-observer variation) were 0.04 cm(95%CI:-0.59-0.66)and 0.47 cm (95%CI:-0.53-1.47).When stratified,patients not receiving neoadjuvant chemotherapy showed a strong correlation between CT and pathological tumor length(r =0.69,P=0.0014,n=37)than patients that did(r= 0.13,P=0.43,n=19).median survival with CT tumor length>5.6 cm was poorer than with smaller tumors,but the difference was not statistically ***:Esophageal tumor length assessed using CT does not reflect pathological tumor extent and should not be the only modality used for management decisions,particularly for planning radiotherapy.

关键词： Computed tomography Esophageal cancer Radiotherapy

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Diel and seasonal patterns of variation in the singing behaviour of Savannah Sparrows (Passerculus sandwichensis)

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Avian Research 2019年第3期10卷 336-343页

作者： Ines G.moran Katrina C.Lukianchuk Stephanie.m.Doucet Amy E.m.Newman Heather williams D.Ryan Norris Daniel J.mennill Department of Biological Sciences University of WindsorWindsorON N9B3P4Canada Department of Integrative Biology University of GuelphGuelphON N1G2W1Canada Biology Department Williams CollegeWilliamstownMD 01267USA

Background:The vocalizations of birds are dynamic traits that often vary in output with time of day and time of *** quantifying patterns of diel and seasonal variation in vocal output,we can gain insight into the ecology and evolution of birds and the function of their *** this investigation,we quantified diel and seasonal variation in song output by studying a breeding population of Savannah Sparrows (Passerculus sandwichensis).methods:We used autonomous recorders to collect extensive recordings across the breeding season in a long-term, colour-marked study population of Savannah Sparrows in eastern *** described diel and seasonal variation across five different breeding stages based on recordings of more than 50,000 songs from 34 ***:During the pre-breeding stage, prior to female arrival, males sang a pronounced dawn chorus with a peak in song output during the early *** the breeding stage,in contrast,the dawn chorus was diminished and males instead exhibited a pronounced dusk chorus with a peak in song output during the *** the breeding season,the highest levels of song output occurred in late April and early may,soon after males arrived on the breeding grounds,and the lowest levels occurred in August,prior to the departure of birds for the wintering ***:These patterns suggest that Savannah Sparrows' early-season dawn choruses are directed at males and serve a territorial defense ***-season dusk choruses,in contrast, appear to play a role in attracting mates and possibly acoustic mate guarding.

关键词： Bird song Breeding activities Circadian rhythms Seasonal variation in song

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Behavior and modeling of tessellated shear walls in a structural frame system

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Resilient Cities and Structures 2023年第1期2卷 152-161页

作者： mohammad Syed Pinar Okumus Negar Elhami-Khorasani brandon E.Ross michael Carlos Barrios Kleiss Zachry Department of Civil and Environmental Engineering Texas A&M UniversityCollege StationTX 77843USA Department of Civil Structuraland Environmental EngineeringUniversity at BuffaloBuffaloNY 14260USA Glenn Department of Civil Engineering Clemson UniversityClemsonSC 29634-0911USA School of Architecture Clemson UniversityClemsonSC 29634-0911USA

This paper studies the behavior of a reinforced concrete(RC)structural frame employing a tessellated structuralarchitectural(TeSA)shear wall as the lateral-load resisting *** walls are made of interlocking modules(tiles)that provide easier repairability and replaceability.A nonlinearﬁnite element model of a TeSA wall with tiles interlocking in one direction(1-D interlocking)is validated using test *** RC frame from a building is modeled with a 1-D interlocking TeSA shear *** effects of varying rigidity of the wall-frame connections(rigid,hinged,slotted)on the lateral strength of the system and the axial load demands of the gravity-load resisting systems are ***,the effect of connection details on the damage of the TeSA wall is also *** study shows that the lateral strength of the system is the highest with a rigid connection between the wall and the system,followed by the system with hinged *** connections,which provided no vertical coupling between the wall and the frame result in the lowest lateral *** wall experienced“slight damage”up to a drift ratio of 2%.The system with rigid connections between the wall and the frame experienced the most damage,followed by system with hinged and slotted connections.

关键词： modular shear wall Frame-wall connections Finite-element modeling Resiliency

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Same day yttrium-90 radioembolization with single photon emission computed tomography/computed tomography: An opportunity to improve care during the COVID-19 pandemic and beyond

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World Journal of Gastrointestinal Oncology 2021年第5期13卷 440-452页

作者： mohammad Elsayed mohammad Loya James Galt David m Schuster Zachary L Bercu Janice Newsome David brandon Sonia Benenati Keywan Behbahani Richard Duszak Ila Sethi Nima Kokabi Division of Interventional Radiology and Image-Guided medicine Department of Radiology and Imaging SciencesEmory University School of MedicineAtlantaGA 30322United States Division of Nuclear medicine and molecular Imaging Department of Radiology and Imaging SciencesEmory University School of MedicineAtlantaGA 30322United States

BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has made it more challenging for patients to undergo yttrium-90(Y-90)radioembolization(RE).Same day Y-90 RE provides an opportunity to minimize logistical challenges and infection risk associated with COVID-19,thus improving patient *** To describe the use of same day Y-90 RE with routine single photon emission computed tomography/computed tomography(SPECT/CT)in order to optimize *** All patients were selected for Y-90 RE through a multidisciplinary tumor board,and were screened and tested for COVID-19 infection per institutional protocol.A same day procedure was developed,consisting of angiography,imaging,and Y-90 resin particle *** SPECT/CT after technetium-99m macroaggregated albumin(Tc-99m mAA)administration was performed for assessment of arterial supply,personalized dosimetry,and extrahepatic ***-treatment Y-90 bremsstrahlung SPECT/CT was performed for confirmation of particle delivery,by utilization of energy windowing to limit signal from previously administered Tc-99m mAA *** A total of 14 patients underwent same day Y-90 RE between march and June *** lung shunt fraction was 6.13%(range 3.5%-13.1%).Y-90 RE was performed for a single lesion in 7 patients,while the remaining 7 patients had treatment of multifocal *** largest lesion measured 8.3 *** patients tolerated the procedure well and were discharged the same *** Same day Y-90 RE with resin-based microspheres is feasible,and provides an opportunity to mitigate infection risk and logistical challenges associated with the COVID-19 pandemic and *** recommend consideration of SPECT/CT,especially among patients with complex malignancies,for the potential to improve outcomes and eligibility of patients to undergo same day Y-90 RE.

关键词： Yttrium-90 radioembolization Same day Selective internal radiotherapy Transarterial radioembolization Single photon emission computed tomography/computed tomography Dosimetry COVID-19

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Access to smart devices and utilization of online health resources among older cardiac rehabilitation participants

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World Journal of Cardiology 2020年第5期12卷 203-209页

作者： Abdulghani Saadi Arun Kanmanthareddy mahesh Anantha-Narayanan Karen Hardy mark williams Venkata m Alla Division of Cardiology Creighton University School of MedicineOmahaNE 68124United States CHI Creighton University Medical CenterOmahaNE 68124United States Section of Cardiovascular medicine Yale New Haven HospitalNew HavenCT 06510United States

BACKGROUND Newer models of cardiac rehabilitation(CR)delivery are promising but depend upon patient participation and ability to use technological media including Internet and smart *** To explore the availability of smart devices,current utilization and proficiency of use among older CR program *** Study participants were enrolled from four CR programs in Omaha,Nebraska United States and completed a questionnaire of 28 *** Of 376 participants approached,169 responded(45%).mean age was 71.1(SD±10)*** were 73.5%males,89.7%Caucasians,52%with college degree and 56.9%,with income of 40 K$or *** device ownership was84.5%;desktop computer was the most preferred *** Internet use was 1.9 h/d(SD±1.7);54.3%of participants indicating for general usage but only18.4%pursued health-related *** of other health information modalities was low,29.8%used mobile health applications and 12.5%used wearable *** all participants,72%reported no barriers to using *** and income were associated positively with measures of utilization and with less perceived *** an older group of subjects attending CR,most have access to smart devices and do not perceive significant barriers to Internet ***,there was low utilization of health-related resources suggesting a need for targeted education in this patient population.

关键词： Cardiac rehabilitation Smart devices Internet Perceived barriers

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Hospital outcomes and early readmission for the most common gastrointestinal and liver diseases in the United States:Implications for healthcare delivery

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World Journal of Gastrointestinal Surgery 2021年第2期13卷 141-152页

作者： Somashekar G Krishna brandon K Chu Alecia m Blaszczak Gokulakrishnan Balasubramanian Hisham Hussan Peter P Stanich Khalid mumtaz Alice Hinton Darwin L Conwell Division of Gastroenterology Hepatology and NutritionThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Internal medicine The Ohio State University Wexner Medical CenterColumbusOH 43210United States Division of Biostatistics Ohio State University Wexner Medical CenterColumbusOH 43210United States

BACKGROUND Gastrointestinal(GI)and liver diseases contribute to substantial inpatient morbidity,mortality,and healthcare resource *** ways to reduce the economic burden of healthcare costs and the impact of these diseases is of crucial ***-day readmission rates and related hospital outcomes can serve as objective measures to assess the impact of and provide further insights into the most common GI *** To identify the thirty-day readmission rates with related predictors and outcomes of hospitalization of the most common GI and liver diseases in the United *** A cross-sectional analysis of the 2012 National Inpatient Sample was performed to identify the 13 most common GI *** 2013 Nationwide Readmission Database was then queried with specific International Classification of Diseases,Ninth Revision,Clinical modification *** outcomes were mortality(index admission,calendar-year),hospitalization costs,and thirty-day readmission and secondary outcomes were predictors of thirty-day *** For the year 2013,the thirteen most common GI diseases contributed to 2.4 million index hospitalizations accounting for about$25 *** thirty-day readmission rates were highest for chronic liver disease(25.4%),Clostridium difficile(***)infection(23.6%),functional/motility disorders(18.5%),inflammatory bowel disease(16.3%),and GI bleeding(15.5%).The highest index and subsequent calendar-year hospitalization mortality rates were chronic liver disease(6.1%and 12.6%),*** infection(2.3%and 6.1%),and GI bleeding(2.2%and 5.0%),***-day readmission correlated with any subsequent admission mortality(r=0.798,P=0.001).medicare/medicaid insurances,≥3 Elixhauser comorbidities,and length of stay>3 d were significantly associated with thirty-day readmission for all the thirteen GI *** Preventable and non-chronic GI disease contributed to a significant economic and health

关键词： Gastrointestinal disease Thirty-day readmission Nationwide readmission database Outcomes mortality Cost

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Joint Ofshore Wind and Wave Energy Resources in the Caribbean Sea

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Journal of marine Science and Application 2021年第4期20卷 660-669页

作者： brandon J.Bethel School of marine Sciences Nanjing University of Information Science&TechnologyNanjing 210044China

Complementarities between wind and wave energies have many signifcant advantages that are unavailable with the sole deployment of *** all available wind speed,signifcant wave height,and wave period buoy observations over a 10-year period(i.e.,2009–2019),colocated wind and wave energy resources are *** buoy records are imper-fect,results show that the inner Caribbean Sea(CS)under the infuence of the Caribbean low-level jet has the highest wind energy resource at~1500 W/m^(2),followed by the outer CS at~600 W/m^(2) and Atlantic Ocean(AO)at~550–600 W/m^(2) at a 100 m *** energy was most abundant in the AO at 14 kW/m,followed by the inner CS at 13 kW/m and outer CS at 5 kW/*** average and dominant wave energies can reach a maximum of 10 and 14 kW/m,*** between wind and wave energy resources is observed in the AO,where wave energy is higher than the low wind speed/energy would *** is responsible for this discrepancy;thus,it must be considered not only for wave energy extraction but also for wind turbine fatigue,stability,and power extraction efciency.

关键词： Wave energy Wind energy Colocation Caribbean Sea Small island developing states NDBC buoys

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Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy

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Bone Research 2018年第2期6卷 167-176页

作者： Babita madan mitchell J.mcDonald Gabrielle E.Foxa Cassandra R.Diegel Bart O.williams David m.Virshup Program in Cancer and Stem Cell Biology Duke-NUS Medical School Center for Cancer and Cell Biology and Program for Skeletal Disease and Tumor microenvironment Van Andel Research Institute Department of Pediatrics Duke University

Dysregulated Wnt signaling is associated with the pathogenesis of cancers, fibrosis, and vascular diseases. Inhibition of Wnt signaling has shown efficacy in various pre-clinical models of these disorders. One of the key challenges in developing targeted anti-cancer drugs is to balance efficacy with on-target toxicity. Given the crucial role Wnts play in the differentiation of osteoblasts and osteoclasts, acute inhibition of Wnt signaling is likely to affect bone homeostasis. In this study, we evaluated the skeletal effect of small molecule inhibitor of an o-acyl transferase porcupine（PORCN） that prevents Wnt signaling by blocking the secretion of all Wnts. micro-computed tomography and histomorphometric evaluation revealed that the bones of mice treated with two structurally distinct PORCN inhibitors LGK974 and ETC-1922159（ETC-159） had loss-of-bone volume and density within 4 weeks of exposure. This decreased bone mass was associated with a significant increase in adipocytes within the bone marrow. Notably,simultaneous administration of a clinically approved anti-resorptive, alendronate, a member of the bisphosphonate family,mitigated loss-of-bone mass seen upon ETC-159 treatment by regulating activity of osteoclasts and blocking accumulation of bone marrow adipocytes. Our results support the addition of bone protective agents when treating patients with PORCN *** of bone toxicity can extend the therapeutic utility of Wnt pathway inhibitors.

关键词： Wnt ETC Bone loss Wnt inhibition mitigated concurrent alendronate therapy

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