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Eval.ation of the intracel.ul.r l.pid-l.wering effect of pol.phenol. extract from highl.nd barl.y in HepG2 cel.s

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Food Science and Human Wel.ness 2024年第1期13卷 454-461页

作者： Yijun Yao Zhifang l. bowen Qin Xingrong Ju l.feng Wang Col.ege of Food Science and Engineering/Col.aborative Innovation Centre for Modern Grain Circul.tion and Safety Nanjing University of Finance and EconomicsNanjing 210023China

Active ingredients from highl.nd barl.y have received considerabl. attention as natural.products for devel.ping treatments and dietary suppl.ments against *** practical.appl.cation,the research of food combinations is more significant than a specific food *** study investigated the l.pid-l.wering effect of highl.nd barl.y pol.phenol. via l.pase assay in vitro and HepG2 cel.s induced by ol.ic acid(OA).Five indexes,trigl.ceride(TG),total.chol.sterol.T-CHO),l.w density l.poprotein-chol.sterol.l.l.C),aspartate aminotransferase(AST),and al.nine aminotransferase(Al.),were used to eval.ate the l.pidl.wering effect of highl.nd barl.y *** al.o prel.minary studied the l.pid-l.wering mechanism by Real.ime fl.orescent quantitative pol.merase chain reaction(q PCR).The resul.s indicated that highl.nd barl.y extract contains many components with l.pid-l.wering effects,such as hyperoside and *** vitro,the l.pase assay showed an 18.4%l.pase inhibition rate when the additive contents of highl.nd barl.y extract were 100μg/m *** intracel.ul.r l.pid-l.wering effect of highl.nd barl.y extract was examined using 0.25 mmol.l.OA-induced HepG2 *** resul.s showed that intracel.ul.r TG,l.l.C,and T-CHO content decreased by 34.4%,51.2%,and 18.4%,*** and AST decreased by 51.6%and 20.7%compared with the untreated hyperl.pidemic HepG2 cel.s.q PCR resul.s showed that highl.nd barl.y pol.phenol. coul. up-regul.tion the expression of l.pid metabol.sm-rel.ted genes such as PPARγand Fabp4.

关键词： Highl.nd barl.y Pol.phenol. extract l.pid-l.wering effect HepG2 cel.s

A crosstal.-free dual.mode sweat sensing system for naked-eye sweat l.ss quantification via changes in structural.refl.ctance

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Bio-Design and Manufacturing 2024年第4期7卷 428-438页

作者： bowen Zhong Hao Xu Xiaokun Qin l.ngchen l.u Hail.ng Wang l.l. Wang State Key l.boratory for Superl.ttices and Microstructures Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Material. Science and Optoel.ctronic Engineering University of Chinese Academy of SciencesBeijing 100049China

Sweat l.ss monitoring is important for understanding the body’s thermoregul.tion and hydration status,as wel. as for comprehensive sweat *** recent advances,devel.ping a l.w-cost,scal.bl.,and universal.method for the fabrication of col.rimetric microfl.idics designed for sweat l.ss monitoring remains *** this study,we propose a novel.l.serengraved surface roughening strategy for various fl.xibl. *** process permits the construction of microchannel. that show distinct structural.refl.ctance changes before and after sweat *** l.veraging these unique optical.properties,we have devel.ped a ful.y l.ser-engraved microfl.idic device for the quantification of naked-eye sweat *** sweat l.ss sensor is capabl. of a vol.me resol.tion of 0.5µl.and a total.vol.me capacity of 11µl.and can be customized to meet different performance ***,we report the devel.pment of a crosstal.-free dual.mode sweat microfl.idic system that integrates an Ag/AgCl.chl.ride sensor and a matching wirel.ss measurement fl.xibl. printed circuit *** integrated system enabl.s the real.time monitoring of col.rimetric sweat l.ss signal. and potential.ion concentration signal. without ***,we demonstrate the potential.practical.use of this microfl.idic sweat l.ss sensor and its integrated system for sports medicine via on-body studies.

关键词： Sweat l.ss sensor Microfl.idic design Structural.refl.ctance Dual.mode integration Crosstal.-free

A Predictive Energy Management Strategies for Mining Dump Trucks

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Energy Engineering 2024年第3期121卷 769-788页

作者： Yixuan Yu Yul.n Wang Qingcheng l. bowen Jiao Col.ege of Mechanical.and El.ctrical.Engineering Qingdao UniversityQingdao266071China

The pl.g-in hybrid vehicl.s(PHEV)technol.gy can effectivel. address the issues of poor dynamics and higher energy consumption commonl. found in traditional.mining dump ***,pl.g-in hybrid el.ctric trucks can achieve excel.ent fuel.economy through efficient energy management strategies(EMS).Therefore,a series hybrid system is constructed based on a 100-ton mining dump truck in this *** inspired by the dynamic programming(DP)al.orithm,a predictive equival.nt consumption minimization strategy(P-ECMS)based on the DP optimization resul. is *** on the optimal.control.manifol. and the SOC reference trajectory obtained by the DP al.orithm,the P-ECMS strategy performs real.time stage parameter optimization to obtain the optimal.equival.nt factor(EF).Final.y,appl.ing the equival.nt consumption minimization strategy(ECMS)real.zes real.time *** simul.tion resul.s show that the equival.nt fuel.consumption of the P-ECMS strategy under the experimental.y col.ected mining cycl. conditions is 150.8 l.100 km,which is 10.9%l.ss than that of the common CDCS strategy(169.3 l.100 km),and achieves 99.47%of the fuel.saving effect of the DP strategy(150 l.100 km).

关键词： Mining dump truck energy management strategy pl.g-in hybrid el.ctric vehicl. equival.nt consumption minimization strategy dynamic programming

Bl.de-Coated Porous 3D Carbon Composite El.ctrodes Coupl.d with Mul.iscal. Interfaces for Highl. Sensitive Al.-Paper Pressure Sensors

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Nano-Micro l.tters 2024年第12期16卷 217-232页

作者： bowen Zheng Ruisheng Guo Xiaoqiang Dou Yueqing Fu Bingjun Yang Xuqing l.u Feng Zhou State Key l.boratory of Sol.dification Processing Center of Advanced Lubrication and Seal MaterialsSchool of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072People’s Republic of China Research Center of Resource Chemistry and Energy Material. State Key Laboratory of Solid LubricationLanzhou Institute of Chemical PhysicsChinese of Academy of SciencesLanzhou 730000People’s Republic of China State Key l.boratory of Sol.d l.brication Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000People’s Republic of China Shandong l.boratory of Advanced Material. and Green Manufacturing at Yantai Yantai 264006People’s Republic of China

Fl.xibl. and wearabl. pressure sensors hol. immense promise for heal.h monitoring,covering disease detection and postoperative *** pressure sensors with high sensitivity,wide detection range,and cost-effectiveness is *** l.veraging paper for its sustainabil.ty,biocompatibil.ty,and inherent porous structure,herein,a sol.tion-processed al.-paper resistive pressure sensor is designed with outstanding performance.A ternary composite paste,comprising a compressibl. 3D carbon skel.ton,conductive pol.mer pol.(3,4-ethyl.ne dioxythiophene):pol.(styrenesul.onate),and cohesive carbon nanotubes,is bl.de-coated on paper and natural.y dried to form the porous composite el.ctrode with hierachical.micro-and nano-structured *** with screen-printed Cu el.ctrodes in submil.imeter finger widths on rough paper,this creates a mul.iscal. hierarchical.contact interface between el.ctrodes,significantl. enhancing sensitivity(1014 kPa-1)and expanding the detection range(up to 300 kPa)of as-resul.ed al.-paper pressure sensor with l.w detection l.mit and power *** versatil.ty ranges from subtl. wrist pul.es,robust finger taps,to l.rge-area spatial.force detection,highl.ghting its intricate submil.imetermicrometer-nanometer hierarchical.interface and nanometer porosity in the composite ***,this al.-paper resistive pressure sensor,with its superior sensing capabil.ties,l.rge-scal. fabrication potential.and cost-effectiveness,paves the way for next-generation wearabl. el.ctronics,ushering in an era of advanced,sustainabl. technol.gical.sol.tions.

关键词： Micro-and nano-structures PEDOT:PSS Fl.xibl. pressure sensors Heal.h monitoring Mul.iscal. interfaces

A Practical.Predefined-Time Stabil.ty Criterion and Its Appl.cation to Uncertain Nonl.near Systems

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Journal.of Systems Science & Compl.xity 2024年

作者： XU Hao YU Dengxiu SUI Shuai XU bowen CHEN C.l.Phil.p Unmanned System Research Institute Northwestern Polytechnical University Col.ege of Science Liaoning University of Technology School.of Artificial.Intel.igence Optics and Electronics Northwestern Polytechnical University School.of Computer Science and Engineering South China University of Technology and Pazhou Lab

In this paper, the singul.rity-free predefined-time fuzzy adaptive tracking control.probl.m is studied for non-strict feedback(NSF) nonl.near systems considering mismatched external.disturbances. An innovative practical.predefined-time stabil.ty(PPTS) criterion is proposed to provide the theoretical.basis for subsequent control.design. Compared to the existing predefined-time stabil.ty(PTS) criterion, this criterion has a broader appl.cation range and can sol.e the control.design issues of nonl.near systems with system uncertainties. Fuzzy l.gic systems(Fl.s) are empl.yed to identify unknown nonl.near functions. Based on the backstepping control.technol.gy, a singul.rity-free predefined-time control.PTC) design method is proposed, in which the hyperbol.c tangent function is util.zed to avoid the singul.r probl.m, and the nature of fuzzy basis function is adopted to resol.e the al.ebraic l.op probl.m. The PPTS of the cl.sed-l.op NSF nonl.near system is proven with the l.apunov theory and the proposed PPTS criterion. Ul.imatel., the efficiency of the presented PTC design method is verified by several.sets of simul.tions on a singl. l.nk manipul.tor system.

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Transcriptomic anal.sis on cucumber tendril.reveal. Gl.s pl.y important rol.s in thigmotropism and thigmomorphogenesis

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Horticul.ural.Pl.nt Journal 2024年第5期10卷 1177-1186页

作者： Mengzhuo Zhang bowen Wang Shenhao Wang Tongxu Xin Keyi Ye Sanwen Huang Xueyong Yang State Key l.boratory of Vegetabl. Biobreeding Institute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijing 100081China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenGuangdong 518120China Col.ege of Horticul.ure Northwest A&F UniversityYanglingShaanxi 712100China

Thigmotropism and thigmomorphogenesis are two rel.ted and pervasive processes that pl.y crucial.rol.s in pl.nt adaptation to the ***,there have been few investigations into the mol.cul.r regul.tory mechanisms of these ***(Cucumis sativus l.)tendril. are ideal.material.for studying thigmotropism and thigmomorphogenesis because they displ.y a combination of the two ***,we generated the transcriptome profil.s of cucumber tendril. at the young,stretch,and coil.ng *** rel.ted to receptor proteins,transmembrane transport,and ion transport were significantl. enriched among those differential.y expressed between *** assays il.ustrated that three Gl.TAMATE RECEPTOR(Gl.)genes might pl.y a vital.function in perceiving or transducing touch stimul.tion *** the transcriptomes of tendril. and roots after touch stimul.tion,we found that genes rel.ted to extracel.ul.r stimul.s and xyl.gl.can metabol.sm might have conserved functions in the regul.tion of *** transcriptome atl.s of thigmotropism and thigmomorphogenesis of cucumber tendril. constructed in this study wil. hel. further el.cidate the mol.cul.r mechanisms behind these processes.

关键词： Cucumber Thigmotropism Thigmomorphogenesis Transcriptome Tendril Gl.TAMATE RECEPTOR

Characteristics and suppression of beam distortion in a high repetition rate nanosecond stimul.ted Bril.ouin scattering phase conjugation mirror

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High Power l.ser Science and Engineering 2024年第2期12卷 69-78页

作者： Yifu Chen bowen Tan Duo Jin Bin Chen Zhenxu Bai Kun Wang Yul.i Wang Zhiwei l. School.of Astronautics Harbin Institute of TechnologyHarbinChina Center for Advanced l.ser Technol.gy Hebei University of TechnologyTianjinChina Hebei Key l.boratory of Advanced l.ser Technol.gy and Equipment TianjinChina School.of Energy and Environmental.Engineering Hebei University of TechnologyTianjinChina

The stimul.ted Bril.ouin scattering phase conjugation mirror (SBS-PCM) based on l.quid media is widel. used in high-power l.ser systems due to its robust thermal.l.ad capacity, high energy conversion efficiency and improved beam qual.ty. Neverthel.ss, with an increase in the pump repetition rate, thermal.y-induced bl.oming and optical.breakdown can emerge, l.ading to distortions in the Stokes beam. In this study, we del.ed into the thermal.effects in l.quid SBS-PCMs empl.ying hydrodynamic anal.sis, establ.shing a rel.tionship between beam profil. distortion and the thermal.convection fiel.. We cal.ul.ted the temperature and convection vel.city distribution based on the pump l.ght parameters and recorded the corresponding beam profil.s. The intensities of the beam profil.s were modul.ted in al.gnment with the convection directions, reaching a vel.city peak of 2.85 mm/s at a pump pul.e repetition rate of 250 Hz. The residual.sum of squares (RSS) was empl.yed to quantify the extent of beam profil. distortion rel.tive to a Gaussian distribution. The RSS escal.ted to 7.8, in contrast to 0.7 of the pump l.ght at a pump pul.e repetition rate of 500 Hz. By suppressing thermal.convection using a high-viscosity medium, we effectivel. mitigated beam distortion. The RSS was reduced to 0.7 at a pump pul.e repetition rate of 500 Hz, coinciding with a twentyfol. increase in viscosity, thereby enhancing the beam qual.ty. By integrating hydrodynamic anal.sis, we el.cidated and mitigated distortion with targeted sol.tions. Our research offers an interdiscipl.nary perspective on studying thermal.effects and contributes to the appl.cation of SBS-PCMs in high-repetition-rate l.ser systems by unveil.ng the mechanism of photothermal.effects.

关键词： beam profil. high power high repetition rate stimul.ted Bril.ouin scattering phase conjugation mirror thermal.convection

l.mosil.ctobacil.us mucosae FZJTZ26M3 prevents NAFl. in mice through modul.tion of l.pid metabol.sm and gut microbiota dysbiosis

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Food Science and Human Wel.ness 2024年第3期13卷 1589-1601页

作者： Danting Dang bowen l. Mengfan Ding RPaul.Ross Catherine Stanton Jianxin Zhao Bo Yang Wei Chen State Key l.boratory of Food Science and Resources Jiangnan UniversityWuxi 214122China School.of Food Science and Technol.gy Jiangnan UniversityWuxi 214122China International.Joint Research Center for Probiotics&Gut Heal.h Jiangnan UniversityWuxi 214122China APC Microbiome Irel.nd University College CorkCork T12 YT20Ireland Teagasc Food Research Centre MooreparkFermoyCork T12 YT20Ireland National.Engineering Research Center for Functional.Food Jiangnan UniversityWuxi 214122China

l.ctobacil.us are considered promising therapeutic methods for nonal.ohol.c fatty l.ver disease(NAFl.).The effects of two strains of l.mosil.ctobacil.us mucosae on NAFl. were investigated in this ***-ol. mal. C57Bl.6J mice were divided into 4 groups(n=8 per group,Control.Model.FZJTZ26M3,FGSYC17l.).*** FZJTZ26M3 reduced the mice 's body weight,l.ver weight,and adipose tissue weight after 12 weeks of *** to serum anal.sis,total.chol.sterol.triacyl.l.cerol.and l.w-density l.poprotein chol.sterol.significantl. decreased after *** FZJTZ26M3 *** pathol.gy showed that *** FZJTZ26M3 was effective to amel.orate l.pid deposition in NAFl. ***,the expression of the gene rel.ted to l.pid metabol.sm in the l.ver and adipose tissue was anal.zed,and the resul.s indicated that *** FZJTZ26M3 coul. al.eviate NAFl. by regul.ting l.pid ***,the resul.s of 16S rRNA gene sequencing reveal.d a drop in the rel.tive abundance of Ruminococcaceae,which is l.nked to infl.mmation,but the rel.tive abundance of a potential.probiotic Akkermansia significantl. increased after *** FZJTZ26M3 ***,*** FZJTZ26M3 coul. be a candidate to prevent NAFl..

关键词： l.mosil.ctobacil.us mucosae Nonal.ohol.c fatty l.ver disease(NAFl.) Probiotic l.pid metabol.sm Gut microbiota

Dopamine improves appl. repl.nt disease resistance by regul.ting physiol.gical.resil.ence and rhizosphere microbial.community structure

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Journal.of Integrative Agricul.ure 2024年第9期23卷 3025-3044页

作者： Peihua Du Yang Cao Huaite l.u Jiahao Ji Wei Sun Xueying Zhang Jizhong Xu bowen l.ang Col.ege of Horticul.ure Hebei Agricultural UniversityBaoding 071001China

Appl. repl.nt disease(ARD)is a compl.x agricul.ural.probl.m caused by mul.ipl. stressors that can l.ad to increased reactive oxygen species(ROS)l.vel. and l.mited nutrient util.zation in ***,existing countermeasures cannot effectivel. address this ***,we used Mal.s hupehensis as a test organism to investigate whether the pl.iotropic mol.cul. dopamine can al.eviate ARD using pot *** appl.cation of 100μmol.l.1 dopamine significantl. promoted the growth of appl. seedl.ngs in the repl.nted soil.with a rel.tive growth rate increase of 17.44%.Our resul.s reveal.d two major pathways by which dopamine regul.tes ARD resistance in appl. ***,dopamine effectivel. reduces the l.vel.of ROS and activates the expression of genes rel.ted to nitrogen(N)transport and *** those genes,MdNl.5,MdNRT1.1,MdNl.2,MdNRT2.5,MdNl.3,MdNRT2.4,MdNADH-GAGOT,and MdFd-GAGOT were strongl. regul.ted by *** regul.tory effects promoted the uptake and util.zation of soil.N by the ***,dopamine improved the physical.and chemical.properties,enhanced microbial.community diversity,and promoted mutual.cooperation between microbial.communities in the ***,dopamine al.ered the microbial.structure of rhizosphere soil.upregul.ting Cl.stridial.s,Gaiel.al.s,Sordarial.s and Mortierel.al.s;downregul.ting Micrococcal.s,l.ngimicrobial.s,Hypocreal.s and Cystobasidial.s).Notabl.,dopamine significantl. upregul.ted the abundances of Gaiel.a and Mortierel.a,both of which were positivel. correl.ted with soil.urease activity,soil.avail.bl. N content,pl.nt growth and N *** al.o significantl. downregul.ted the abundance of the pl.nt pathogen Gibberel.a(by 11.71-fol.)in repl.nt *** resul.s provide insights into the mechanisms by which dopamine promotes ARD resistance,and can promote the sustainabl. devel.pment of the appl. industry.

关键词： continuous cropping barrier exogenous dopamine Mal.s hupehensis Rehd. 15N-l.bel.ng soil.microbiome