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Tidal effects based on a GUP-induced effective metric

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Communications in Theoretical Physics 2024年第9期76卷 63-72页

作者： Soon-Tae Hong Yong-wan kim Young-Jai Park Center for Quantum Spacetime and Department of Physics Sogang UniversitySeoul 04107Republic of Korea Department of Physics and Research Institute of Physics and Chemistry Jeonbuk National UniversityJeonju 54896Republic of Korea Department of Physics Sogang UniversitySeoul 04107Republic of Korea

In this paper,we study tidal forces in the Schwarzschild black hole,whose metric explicitly includes a generalized uncertainty principle(GUP)*** also investigate interesting features of the geodesic equations and tidal effects that are dependent on the GUP parameterαrelated to a minimum ***,by solving the geodesic deviation equations explicitly with appropriate boundary conditions,we show thatαin the effective metric affects both the radial and angular components of the geodesic equation,particularly near the singularities.

关键词： generalized uncertainty principle geodesic deviation equation effective metric

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Risk factor for ischemic-type biliary lesion after ABO-incompatible living donor liver transplantation

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World Journal of Gastroenterology 2016年第30期22卷 6925-6935页

作者： Jun Bae Bang bong-wan kim Young Bae kim Hee-Jung wang Hyun Yeong Lee Joohyun Sim Taegyu kim Kyeong Lok Lee Xu-Guang Hu Wei Mao Department of Liver Transplantation and Hepatobiliary Surgery Ajou University School of Medicine Department of Pathology Ajou University School of Medicine Department of Biostatistics Ajou University School of Medicine

AIM: To evaluate the risk factors for ischemic-type biliary lesion(ITBL) after ABO-incompatible(ABO-I) adult living donor liver transplantation(ALDLT).METHODS: Among 141 ALDLTs performed in our hospital between 2008 and 2014, 27(19%) were ABO-I ALDLT and 114 were ABO-identical/compatible ALDLT. In this study, we extensively analyzed the clinico-pathological data of the 27 ABO-I recipients to determine the risk factors for ITBL after ABO-I ALDLT. All ABO-I ALDLT recipients underwent an identical B-cell depletion protocol with preoperative rituximab, plasma exchange(PE), and operative splenectomy. The median follow-up period after transplantation was 26 mo. The clinical outcomes of the 27 ABO-I ALDLT recipients were compared with those of 114 ABO-identical/compatible ALDLT ***: ITBL occurred in four recipients(14.8%) between 45 and 112 d after ABO-I ALDLT. The overall survival rates were not different between ABO-I ALDLT and ABO-identical/compatible ALDLT(P = 0.303). Among the ABO-I ALDLT recipients, there was no difference between patients with ITBL and those without ITBL in terms of B-cell and T-cell count, serum isoagglutinin titers, number of PEs, operative time and transfusion, use of graft infusion therapy, or number of remnant B-cell follicles and plasma cells in the spleen. However, the perioperative NK cell counts in the blood of patients with ITBL were significantly higher than those in the patients without ITBL(P 150/μL and postoperative NK cell count > 120/μL were associated with greater relative risks(RR) for development of ITBL(RR = 20 and 14.3, respectively, P < 0.05). CONCLUSION: High NK cell counts in a transplant recipient's blood are associated with ITBL after ABO-I ALDLT. Further research is needed to elucidate the molecular mechanism of NK cell involvement in the development of ITBL.

关键词： Liver transplantation ABO-incompatibility Ischemic-type biliary lesion Natural killer cell

Enhancement of porcine in vitro embryonic development through luteolin‑mediated activation of the Nrf2/Keap1 signaling pathway

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Journal of Animal Science and Biotechnology 2024年第2期15卷 600-613页

作者： Se-Been Jeon Pil-Soo Jeong Min Ju kim Hyo-Gu Kang bong-Seok Song Sun-Uk kim Seong-Keun Cho Bo-Woong Sim Futuristic Animal Resource&Research Center(FARRC) Korea Research Institute of Bioscience and Biotechnology(KRIBB)Cheongju 28116Republic of Korea Department of Animal Science College of Natural Resources&Life SciencePusan National UniversityMiryang 50463Republic of Korea Department of Animal Science and Biotechnology College of Agriculture and Life ScienceChungnam National UniversityDaejeon 34134Republic of Korea Department of Functional Genomics University of Science and TechnologyDaejeon 34113Republic of Korea Department of Animal Science Life and Industry Convergence Research Institute(RICRI)College of Natural Resources&Life SciencePusan National UniversityMiryang 50463Republic of Korea

Background Oxidative stress,caused by an imbalance in the production and elimination of intracellular reactive oxygen species(ROS),has been recognized for its detrimental effects on mammalian embryonic ***(Lut)has been documented for its protective effects against oxidative stress in various ***,its specific role in embryonic development remains *** study aims to investigate the influence of Lut on porcine embryonic development and to elucidate the underlying *** After undergoing parthenogenetic activation(PA)or in vitro fertilization,embryos supplemented with 0.5μmol/L Lut displayed a significant enhancement in cleavage and blastocyst formation rates,with an increase in total cell numbers and a decrease in the apoptosis rate compared to the *** on D2 and D6 revealed that embryos with Lut supplementation had lower ROS levels and higher glutathione levels compared to the ***,Lut supplementation significantly augmented mitochondrial content and membrane ***,activation of the Nrf2/Keap1 signaling pathway was observed in embryos supplemented with Lut,leading to the upregulation of antioxidant-related gene transcription *** further validate the relationship between the Nrf2/Keap1 signaling pathway and effects of Lut in porcine embryonic development,we cultured PA embryos in a medium supplemented with brusatol,with or without the inclusion of *** positive effects of Lut on developmental competence were negated by brusatol *** Our findings indicate that Lut-mediated activation of the Nrf2/Keap1 signaling pathway contributes to the enhanced production of porcine embryos with high developmental competence,and offers insight into the mechanisms regulating early embryonic development.

关键词： Luteolin Mitochondrial function Nrf2/Keap1 signaling pathway Oxidative stress Porcine embryo development

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Machine Learning-Assisted Fabrication of PCBM-Perovskite Solar Cells with Nanopatterned TiO2 Layer

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Energy & Environmental Materials 2024年第4期7卷 223-230页

作者： Siti Norhasanah Sanimu Hwa-Young Yang Jeevan Kandel Ye-Chong Moon Gangasagar Sharma Gaudel Seung-Ju Yu Yong Ju kim Sejung kim bong-Hyun Jun Won-Yeop Rho Graduate School of Integrated Energy-AI Jeonbuk National University School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology (UNIST) Department of Herbal Medicine Resources College of Environmental and Bioresource Sciences Jeonbuk National University School of Chemical Engineering Jeonbuk National University Department of Bioscience and Biotechnology Konkuk University School of International Engineering and Science Jeonbuk National University

To unlock the full potential of PSCs,machine learning （ML） was implemented in this research to predict the optimal combination of mesoporous-titanium dioxide （mp-TiO2） and weight percentage （wt%） of phenyl-C61-butyric acid methyl ester （PCBM）,along with the current density(Jsc),open-circuit voltage (Voc),fill factor （ff）,and energy conversion efficiency （ECE）.

关键词： machine learning nanopatterning PCBM perovskite solar cells prediction

Indolocarbazole-Based Small Molecule Cathode-Active Material Exhibiting Double Redox for High-Voltage Li-Organic Batteries

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Energy & Environmental Materials 2024年第5期7卷 90-98页

作者： Hyunji Park Hyojin Kye Jong-Sung Lee Young-Chang Joo Dong Joo Min bong-Gi kim Soo Young Park Ji Eon Kwon Laboratory for Supramolecular Optoelectronic Materials (LSOM) Department of Materials Science and Engineering Research Institute of Advanced Materials (RIAM) Seoul National University Functional Composite Materials Research Center Jeonbuk Institute of Advanced Composite Materials Korea Institute of Science and Technology (KIST) Department of Organic and Nano System Engineering Konkuk University Department of Materials Science and Engineering Seoul National University Department of JBNU-KIST Industry Academia Convergence Research Jeonbuk National University

Most organic electrode materials （OEMs） for rechargeable batteries employ n-type redox centers, whose redox potentials are intrinsically limited <3.0 V versus Li+/Li. However, p-type materials possessing high redox potentials experience low specific capacities because they are capable of only a single redox reaction within the stable electrochemical window of typical ***, we report 5,11-diethyl-5,11-dihydroindolo[3,2-b]carbazole （DEICZ） as a novel p-type OEM, exhibiting stable plateaus at high discharge potentials of3.44 and 4.09 V versus Li+/Li. Notably, the second redox potential of DEICZ is within the stable electrochemical window. The mechanism of the double redox reaction is investigated using both theoretical calculations and experimental measurements, including density functional theory calculations, ex situ electron spin resonance, and X-ray photoelectron spectroscopy. Finally,hybridization with single-walled carbon nanotubes （SWCNT） improves the cycle stability and rate performance of DEICZ owing to theπ–πinteractions between the SWCNT and co-planar molecular structure of DEICZ, preventing the dissolution of active materials into the electrolyte. The DEICZ/SWCNT composite electrode maintains 70.4%of its initial specific capacity at 1-C rate and also exhibits high-rate capability, even performing well at 100-C rate.

关键词： composite electrodes flexible batteries indolocarbazoles organic rechargeable batteries p-type

活体部分肝移植时利用冻藏大动脉片重建流出道

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活体部分肝移植时利用冻藏大动脉片重建流出道

2008年浙江省外科学术年会

作者： bong-wan kim Byong-Ku Bae Hee-Jung wang Department of Surgery Ajou University School of Medicine

绪论目前,因尸体肝移植供肝不足,而广泛利用肝右叶行活体部分肝移植。在活体部分肝移植时,为了取得适当的肝容积,有必要重建肝中静脉。作者在此介绍利用冻藏大动脉片重建肝右叶流出道的新技术。

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以辅助性肝移植成功治疗血友病1例

以辅助性肝移植成功治疗血友病1例

SUV39H1-driven NFATc1 methylation is essential for the c-Cbl-mediated degradation of NFATc1 in an osteoclast lineage

2008年浙江省外科学术年会

作者： Hee-Jung wang bong-wan kim Byong-Ku Bae Department of Surgery and Hematology Ajou University School of Medicine

背景及目的对血友病患者来说,补充凝血因子是控制出血的方法。但是,受到多名供者的感染凝血因子,使得患者对抗病毒感染,肝硬化,肝细胞癌更加脆弱。2007年1月,我们成功的对肝细胞癌合并肝硬化的血友病患者行活体部分肝移植。虽然,没有对...

背景及目的对血友病患者来说,补充凝血因子是控制出血的方法。但是,受到多名供者的感染凝血因子,使得患者对抗病毒感染,肝硬化,肝细胞癌更加脆弱。2007年1月,我们成功的对肝细胞癌合并肝硬化的血友病患者行活体部分肝移植。虽然,没有对无肝硬化及肝细胞癌的血友病患者施行肝移植的报道。可是,我们认为肝移植有可能成为治疗血友病的有效选择。

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Genes & Diseases 2024年第4期11卷 86-89页

作者： Do-Won Jeong Hye-Jin kim Jong-wan Park Seulbee Lee Hyeryeon Jung Eugene C.Yi Nacksung kime Yang-Sook Chun Department of Biomedical Sciences Seoul National University College of MedicineSeoul 03080Republic of Korea Department of Physiology Seoul National University College of MedicineSeoul 03080Republic of Korea Ischemic/Hypoxic Disease Institute Seoul National University College of MedicineSeoul 03080Republic of Korea Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology and College of Medicine Or College of PharmacySeoul National UniversitySeoul 03080Republic of Korea Department of Pharmacology Chonnam National University Medical SchoolGwangju 61469Republic of Korea

Bone undergoes continuous remodeling by tightly-coordinated actions of bone-resorbing osteoclasts and boneforming osteoblasts.1 Recent studies document that the dysregulation of histone methylation profiles is associated with the progression of ***,the specific epigenetic modifiers are incompletely *** this study,we demonstrate an inhibitory role of a variegation 3-9 homolog 1(SUV39H1)in osteoclast formation.

关键词： osteoclast remodeling incomplete

Trifunctional robust electrocatalysts based on 3D Fe/N-doped carbon nanocubes encapsulating Co4N nanoparticles for efficient battery-powered water electrolyzers

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Carbon Energy 2024年第6期6卷 124-139页

作者： Hyung Wook Choi Hongdae Lee Jun Lu Seok Bin Kwon Dong In Jeong Beum Jin Park Jiwon kim bong Kyun Kang Gun Jang Dae Ho Yoon Ho Seok Park SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea School of Chemical Engineering Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea Department of Electronic Materials Devicesand Equipment EngineeringSoonchunhyang UniversityAsan CityChungnamRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwon-siGyeonggi-doRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences and Technology(SAIHST)Sungkyunkwan UniversitySuwonRepublic of Korea

Herein,we have designed a highly active and robust trifunctional electrocatalyst derived from Prussian blue analogs,where Co_(4)N nanoparticles are encapsulated by Fe embedded in N-doped carbon nanocubes to synthesize hierarchically structured Co_(4)N@Fe/N-C for rechargeable zinc-air batteries and overall water-splitting *** confirmed by theoretical and experimental results,the high intrinsic oxygen reduction reaction,oxygen evolution reaction,and hydrogen evolution reaction activities of Co_(4)N@Fe/N-C were attributed to the formation of the heterointerface and the modulated local electronic ***,Co_(4)N@Fe/N-C induced improvement in these trifunctional electrocatalytic activities owing to the hierarchical hollow nanocube structure,uniform distribution of Co_(4)N,and conductive encapsulation by Fe/***,the rechargeable zinc-air battery with Co_(4)N@Fe/N-C delivers a high specific capacity of 789.9 mAh g^(-1) and stable voltage profiles over 500 ***,the overall water electrolyzer with Co_(4)N@Fe/N-C achieved better durability and rate performance than that with the Pt/C and IrO2 catalysts,delivering a high Faradaic efficiency of 96.4%.Along with the great potential of the integrated water electrolyzer powered by a zinc-air battery for practical applications,therefore,the mechanistic understanding and active site identification provide valuable insights into the rational design of advanced multifunctional electrocatalysts for energy storage and conversion.

关键词： battery-powered electrolyzers hierarchical structure Prussian blue analog trifunctional electrocatalyst zinc-air battery