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Modulating sparks in a pulse train for repetitive and energy efficient plasma generation

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High Voltage 2023年第6期8卷 1168-1179页

作者： bo yin Yifei Zhu Yun Wu Institute of Aero‐Engine School of Mechanical EngineeringXi'an Jiaotong UniversityXi'anChina School of Electrical Engineering Xi'an Jiaotong UniversityXi'anChina Science and Technology of Plasma Dynamics Laboratory Airforce Engineering UniversityXi'anChina

Spark is a widely studied plasma source for active species production;however,it ex-periences unstable transitions(*** a thermal arc)at high frequencies or long pulse *** this study,the sparks generated in a pulse train were studied and modulated based on a physics‐corrected deep learning *** results show that a highly repeatable and stable spark plasma source can be achieved by automatically adjusting the voltage amplitude according to the discharge frequency in a high‐frequency pulse train within the time scale of the fluid *** influences of the electron number density increasing mode and modulated driven voltage profiles on the energy efficiencies were also studied.

关键词： Spark pulse energy

VKFQ:A Verifiable Keyword Frequency Query Framework with Local Differential Privacy in Blockchain

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Computers, Materials & Continua 2024年第3期78卷 4205-4223页

作者： Youlin Ji bo yin Ke Gu School of Computer and Communication Engineering Changsha University of Science and TechnologyChangsha410114China

With its untameable and traceable properties,blockchain technology has been widely used in the field of data *** to preserve individual privacy while enabling efficient data queries is one of the primary issues with secure data *** this paper,we study verifiable keyword frequency(KF)queries with local differential privacy in *** the numerical and the keyword attributes are present in data objects;the latter are sensitive and require privacy ***,prior studies in blockchain have the problem of trilemma in privacy protection and are unable to handle KF *** propose an efficient framework that protects data owners’privacy on keyword attributes while enabling quick and verifiable query processing for KF *** framework computes an estimate of a keyword’s frequency and is efficient in query time and verification object(VO)size.A utility-optimized local differential privacy technique is used for privacy *** data owner adds noise locally into data based on local differential privacy so that the attacker cannot infer the owner of the keywords while keeping the difference in the probability distribution of the KF within the privacy *** propose the VB-cm tree as the authenticated data structure(ADS).The VB-cm tree combines the Verkle tree and the Count-Min sketch(CM-sketch)to lower the VO size and query *** VB-cm tree uses the vector commitment to verify the query *** fixed-size CM-sketch,which summarizes the frequency of multiple keywords,is used to estimate the KF via hashing *** conduct an extensive evaluation of the proposed *** experimental results show that compared to theMerkle B+tree,the query time is reduced by 52.38%,and the VO size is reduced by more than one order of magnitude.

关键词： Security data sharing blockchain data query privacy protection

Review for chiral-at-metal complexes and metal-organic framework enantiomorphs

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Science Bulletin 2017年第19期62卷 1344-1354页

作者： Zi-Hong Yan Donghao Li Xue-bo yin College of Chemistry and Environmental Sciences Laboratory of Xinjiang Native Medicinal and Edible Plant Resources ChemistryKashgar University Key Laboratory of Natural Resource of the Changbai Mountain and Functional Molecular Ministry of EducationYanbian University State Key Laboratory of Medicinal Chemical Biology and Tianjin Key Laboratory of Biosensing and Molecular Recognition College of ChemistryNankai University

This review discusses chiral-at-metal complexes and introduces enantiomorphs from assembly *** to the diverse coordination number and activity of metal ions as chiral centers, abundant structures for chiral selectivity, catalysis, and polarized light-response are the notable advantages of the chiral-at-metal complexes. The rational design and preparation of linear multi-dentate ligands is a good choice to improve the stability of chiral complexes, such as multi-bonding structure for high stability as a self-limiting system. The bio-significance and potential application of chiral-at-metal complexes are discussed, such as the synergistic effect of catalysis and chiral selectivity of the metal center in *** could be remolded to replace the original central metal ions with highly active rare earth or precious metal ions to form artificial metalloenzyme or to remove the ‘‘redundant" part around the metal center to improve the accessibility of substrate. The polarized light-response mechanism of chiral opsin is introduced in relation to its role in animal migration. Metal-organic frameworks(MOFs) are crystalline and porous materials built from metal nodes or clusters and organic linkers and provide the possibility to prepare artificial enantiomorphs. The preparations, applications, and characterization methods of MOF enatiomorphs are therefore introduced. We hope this review inspires researchers at all levels of their career to consider the title topic in their own research in terms of its application and potential value.

关键词： ChiralityStereoisomerChiral-at-metal complexAssembly enatiomorphChiral metal-organic frameworks

Signaling pathways that regulate axon regeneration

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Neuroscience Bulletin 2013年第4期29卷 411-420页

作者： Saijilafu bo-yin Zhang Feng-Quan Zhou Department of Orthopaedic Surgery The Johns Hopkins University Department of The Solomon H. Snyder Department of Neuroscience The Johns Hopkins University

Neurons in the mammalian central nervous system （CNS） cannot regenerate axons after injury. In contrast, neurons in the mammalian peripheral nervous system and in some non-mammalian models, such as C. elegans and Drosophila, are able to regrow axons. Understanding the molecular mechanisms by which these neurons support axon regeneration will help us find ways to enhance mammalian CNS axon regeneration. Here, recent studies in which signaling pathways regulating naturally-occurring axon regeneration that have been identified are reviewed, focusing on how these pathways control gene expression and growth-cone function during axon regeneration.

关键词： axon regeneration axonal growth signal transduction

Constructing the metabolic network of wheat kernels based on structure-guided chemical modification and multi-omics data

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Journal of Genetics and Genomics 2024年第7期51卷 714-722页

作者： Zhitao Tian Jingqi Jia bo yin Wei Chen National Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research(Wuhan) Huazhong Agricultural UniversityWuhanHubei 430070China Hubei Hongshan Laboratory WuhanHubei 430070China

Metabolic network construction plays a pivotal role in unraveling the regulatory mechanism of biological activities,although it often proves to be challenging and labor-intensive,particularly with non-model *** this study,we develop a computational approach that employs reaction models based on the structure-guided chemical modification and related compounds to construct a metabolic network in *** construction results in a comprehensive structure-guided network,including 625 identified metabolites and additional 333 putative reactions compared with the Kyoto Encyclopedia of Genes and Genomes *** a combination of gene annotation,reaction classification,structure similarity,and correlations from transcriptome and metabolome analysis,a total of 229 potential genes related to these reactions are identified within this *** validate the network,the functionality of a hydroxycinnamoyltransferase(TraesCS3D01G314900)for the synthesis of polyphenols and a rhamnosyltransferase(TraesCS2D01G078700)for the modification of flavonoids are verified through in vitro enzymatic studies and wheat mutant tests,*** research thus supports the utility of structure-guided chemical modification as an effective tool in identifying causal candidate genes for constructing metabolic networks and further in metabolomic genetic studies.

关键词： Metabolic network Chemical modification Genetic study Wheat kernel Multi-omics

Self-folding mechanics of graphene tearing and peeling from a substrate

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Frontiers of physics 2018年第3期13卷 17-28页

作者： Ze-Zhou He yin-bo Zhu Heng-An Wu CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern Mechanics University of Science and Technology of China Hefei 230027 China

Understanding the underlying mechanism in the tearing and peeling processes of graphene is crucial for the further hierarchical design of origami-like folding and kirigami-like cutting of graphene. How- ever, the complex effects among bending moduli, adhesion, interlayer interaction, and local crystal structure during origami-like folding and kirigami-like cutting remain unclear, resulting in challenges to the practical applications of existing theoretical and experimental findings as well as to potential manipulations of graphene in metamaterials and nanodevices. Toward this end, classical molecular dynamics （MD） simulations are performed with synergetie theoretical analysis to explore the tearing and peeling of self-folded graphene from a substrate driven by external force and by thermal activation. It is found that the elastic energy localized at the small folding ridge plays a significant role in the crack trajectory. Due to the extremely small bending modulus of monolayer graphene, its taper angle when pulled by an external force follows a scaling law distinct from that in case of bilayer graphene. With the increase in the initial width of the folding ridge, the self-folded graphene, motivated by thermal fluctuations, can be self-assembled by spontaneous self-tearing and peeling from a substrate. Simultaneously, the scaling law between the taper angle and adhesive energy is independent of the motivations for thermal activation-induced self-assembly and external force tearing, providing effective insights into the underlying physics for graphene-based origami-like folding and kirigami-like cutting.

关键词： graphene tearing self-assembly elastic energy molecular dynamics simulation

Modified ADM1 for modeling free ammonia inhibition in anaerobic acidogenic fermentation with high-solid sludge

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Journal of Environmental Sciences 2017年第2期29卷 58-65页

作者： Jie Bai He Liu bo yin Huijun Ma Xinchun Chen School of Environmental and Civil Engineering Jiangnan UniversityWuxi 214122China

Anaerobic acidogenic fermentation with high-solid sludge is a promising method for volatile fatty acid（VFA） production to realize resource recovery. In this study, to model inhibition by free ammonia in high-solid sludge fermentation, the anaerobic digestion model No. 1（ADM1） was modified to simulate the VFA generation in batch, semicontinuous and full scale sludge. The ADM1 was operated on the platform AQUASIM *** kinds of inhibition forms, e.g., simple inhibition, Monod and non-inhibition forms,were integrated into the ADM1 and tested with the real experimental data for batch and semi-continuous fermentation, respectively. The improved particle swarm optimization technique was used for kinetic parameter estimation using the software MATLAB 7.0. In the modified ADM1, the Ksof acetate is 0.025, the km,acis 12.51, and the KI_NH3is 0.02,respectively. The results showed that the simple inhibition model could simulate the VFA generation accurately while the Monod model was the better inhibition kinetics form in semi-continuous fermentation at pH 10.0. Finally, the modified ADM1 could successfully describe the VFA generation and ammonia accumulation in a 30 m^3full-scale sludge fermentation reactor, indicating that the developed model can be applicable in high-solid sludge anaerobic fermentation.

关键词： High-solid sludge ADM1 Semi-continuous Full scale Free ammonia inhibition

Piezoresistive behavior of elastomer composites with segregated network of carbon nanostructures and alumina

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Nano Materials Science 2023年第3期5卷 312-318页

作者： Chun-Yan Tang Lei Liu Kai Ke bo yin Ming-bo Yang Wei Yang College of Polymer Science and Engineering Sichuan UniversityState Key Laboratory of Polymer Materials EngineeringChengdu610065SichuanChina

Electrically conductive elastomer composites(CECs)with segregated networks of conductive nanofillers show high potential in stretchable strain sensors due to balanced mechanical and electrical properties,yet the sensitivity at low strain is generally insufficient for practical ***,we report an easy and effective way to improve the resistive response to low strain for CECs with segregated network structure via adding stiff alumina into carbon nanostructures(CNS).The CEC containing 0.7 wt%CNS and 5 wt%Al_(2)O_(3) almost sustains the same elasticity(elongation at break of~900%)and conductivity(0.8 S/m)as the control,while the piezoresistive sensitivity is significantly *** polyurethane(TPU)composites with a segregated network of hybrid nanofillers(CNS and Al_(2)O_(3))show much higher strain sensitivity(Gauge factor,GF-566)at low strain(45%strain)due to a local stress concentration effect,this sensitivity is superior to that of TPU/CNS composites(GF-11).Such a local stress concentration effect depends on alumina content and its distribution at the TPU particle *** addition,CECs with hybrid fillers show better reproducibility in cyclic piezoresistive behavior testing than the *** work offers an easy method for fabricating CECs with a segregated filler network offering stretchable strain sensors with a high strain sensitivity.

关键词： Thermoplastic polyurethane Carbon nanostructures Alumina Conductive elastomer composites Stretchable strain sensor

Advances in chloroplast engineering

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Journal of Genetics and Genomics 2009年第7期36卷 387-398页

作者： Huan-Huan Wang Wei-bo yin Zan-Min Hu Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China Graduate University of Chinese Academy of Sciences Beijing 100049 China

The chloroplast is a pivotal organelle in plant cells and eukaryotic algae to carry out photosynthesis, which provides the primary source of the world＇s food. The expression of foreign genes in chloroplasts offers several advantages over their expression in the nucleus： high-level expression, transgene stacking in operons and a lack of epigenetic interference allowing stable transgene expression. In addition, transgenic chloroplasts are generally not transmitted through pollen grains because of the cytoplasmic localization. In the past two decades, great progress in chloroplast engineering has been made. In this paper, we review and highlight recent studies of chloroplast engineering, including chloroplast transformation procedures, controlled expression of plastid transgenes in plants, the expression of foreign genes for improvement of plant traits, the production of biopharmaceuticals, metabolic pathway engineering in plants, plastid transformation to study RNA editing, and marker gene excision system.

关键词： chloroplast (plastid) transformation homologous recombination protein expression marker excision