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3D Printing of Tough Hydrogel Scaffolds with Functional Surface Structures for Tissue Regeneration

Nano-Micro Letters 2025年第2期17卷 18-45页

作者： Ke Yao Gaoying Hong Ximin Yuan Weicheng Kong Pengcheng Xia Yuanrong Li Yuewei Chen Nian liu Jing He Jue Shi Zihe Hu Yanyan Zhou Zhijian Xie yong He State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China Liangzhu Laboratory Zhejiang UniversityHangzhou 310027People’s Republic of China Key Laboratory of 3D Printing Process and Equipment of Zhejiang Province College of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China Stomatology Hospital School of StomatologyZhejiang University School of MedicineHangzhou 310027People’s Republic of China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001People’s Republic of China Institute of Digital Medicine Nanjing First HospitalNanjing Medical UniversityNanjing 210006People’s Republic of China

Hydrogel scaffolds have numerous potential applications in the tissue engineering ***,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and high mechanical *** by Chinese ramen,we propose a universal fabricating method(printing-P,training-T,cross-linking-C,PTC&PCT)for tough hydrogel scaffolds to fill this ***,3D printing fabricates a hydrogel scaffold with desired structures(P).Then,the scaffold could have extraordinarily high mechanical properties and functional surface structure by cycle mechanical training with salting-out assistance(T).Finally,the training results are fixed by photo-cross-linking processing(C).The tough gelatin hydrogel scaffolds exhibit excellent tensile strength of 6.66 MPa(622-fold untreated)and have excellent ***,this scaffold possesses functional surface structures from nanometer to micron to millimeter,which can efficiently induce directional cell ***,this strategy can produce bionic human tissue with mechanical properties of 10 kPa-10 MPa by changing the type of salt,and many hydrogels,such as gelatin and silk,could be improved with PTC or PCT *** experiments show that this scaffold can effectively promote the new generation of muscle fibers,blood vessels,and nerves within 4 weeks,prompting the rapid regeneration of large-volume muscle loss injuries.

关键词： 3D printing Tough hydrogel scaffold Functional surface structure Tissue regeneration Biomaterials

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Recent progress on photoactive nonprecious transition-metal complexes

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Science China Chemistry 2025年第1期68卷 46-95页

作者： Zhong-Liang Gong Hong-Jie Zhang Yan Cheng Jianxun liu Yuhan Ai Yaqin Li Zhihui Feng Qiong Zhang Shaolong Gong yong Chen Chang-Jiang Yao Yuan-Yuan Zhu Liang-Jin Xu Yu-Wu Zhong CAS Key Laboratory of Photochemistry Institute of Chemistry Chinese Academy of Sciences State Key Laboratory of Structural Cemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences School of Chemistry and Chemical Engineering Anhui Key Laboratory of Advanced Catalytic Materials and Reaction EngineeringHefei University of Technology State Key Laboratory of Explosion Science and Safety Protection School of Mechatronical Engineering Beijing Institute of Technology College of Chemistry and Molecular Sciences Hubei Key Lab on Organic and Polymeric Optoelectronic Materials Wuhan University School of Chemistry and Chemical Engineering Anhui University Key Laboratory of Photochemical Conversion and Optoelectronic Materials & CAS-HKU Joint Laboratory on New Materials Technical Institute of Physics and Chemistry Chinese Academy of Sciences

Photoactive complexes of nonprecious transition metals, mainly including those in the first-row and partially the second-row of the Periodic table of elements, have received increasing attention in view of their low cost and long-term sustainability. They are recognized as promising alternatives to noble transition metal complex congeners that have been extensively studied in optoelectronic devices, artificial photosynthesis, photocatalysis, biodiagnostics, and therapeutics, etc. This review is devoted to a comprehensive summary on the classical and recent advances on photoactive nonprecious transition metal complexes, including photoactive Zr, V, Cr, Mo, and W complexes, Mn complexes and hybrids, Fe, Co, Ni, and Cu complexes, and Zn and Cd complexes and hybrids. A particular focus is given on the molecular design, modulation of photophysical and photochemical properties, and applications of the representative and lately-developed nonprecious metal complexes. In addition, a perspective on the future development in this field is provided at the end of this review.

关键词： photoactive metal complexes earth-abundant metals nonprecious metal complexes luminescence photochemistry

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高职校企合作现状和长效运行机制探索——以港口经济视角下的商务英语专业为例

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山东商业职业技术学院学报 2011年第4期11卷 36-39页

作者：施永兵刘岗南通航运职业技术学院江苏南通226009

校企合作,是基于市场和社会需求为目标导向的职业院校和企业双方共同培养人才的一种方式,然而由于各种因素的制约,目前高职商务英语校企合作存在诸多问题,原因主要在于缺乏适合我国国情的校企合作运行机制。港口经济环境下,高职商务英... 详细信息

校企合作,是基于市场和社会需求为目标导向的职业院校和企业双方共同培养人才的一种方式,然而由于各种因素的制约,目前高职商务英语校企合作存在诸多问题,原因主要在于缺乏适合我国国情的校企合作运行机制。港口经济环境下,高职商务英语校企合作能否持续、深入开展,关键在于建立政府主导、院校主动、企业参与的"三位一体"校企合作长效运行机制。

关键词：校企合作长效运行机制港口经济商务英语

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Design and test of cesium atomic concentration detection system based on TDLAS*1

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Optoelectronics Letters 2025年第3期21卷 167-171页

作者： LIANG Lizhen liu Shanhu WU yong WEI Jianglong XIE Yahong Hefei Institutes of Physical Science Chinese Academy of Sciences School of Science Shandong Jianzhu University School of Electronic and Information Engineering Anhui Jianzhu University

In order to better build the neutral beam injector with negative ion source (NNBI), the pre-research on key technologies has been carried out for the comprehensive research facility for fusion technology (CRFFT). Cesium seeding into negative-ion sources is a prerequisite to obtain the required negative hydrogen ion. The performance of ion source largely depends on the cesium conditions in the source. It is very necessary to quantitatively measure the amount of cesium in the source during the plasma on and off periods (vacuum stage).

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Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith Teo En Ning Chang liu Yu-Chi liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

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由圈长分布确定的偶图的几个定理

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上海师范大学学报（自然科学版） 2003年第4期32卷 14-17页

作者：施永兵刘荣官上海师范大学数理信息学院上海200234

阶为n的图G的圈长分布是序列(c_1,c_2,…,c_n),其中c_i是图G中长为i的圈数.得到如下结果:(1)设A E(K_n,n),则当K_(n,n)[A] K_(l,j)或K_(n,n)[A] jK_2时,K_(n,n)—A是由它的圈长分布确定;(2)设A E(K_(n,n),|A|=4,n≥11,则K_(n,n)—A是由... 详细信息

关键词：圈圈长分布偶图圈长分布确定的图

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不同热处理蛋黄脂质对小鼠学习认知能力下降的缓解能力

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食品工业科技 2025年第1期46卷 367-376页

作者：吴瑶刘铭坤方冰张明合肥工业大学食品与生物工程学院安徽合肥230061 中国农业大学营养与健康系北京100083 北京工商大学食品与健康学院北京100048

为探讨不同温度处理下蛋黄脂质对小鼠学习认知能力下降的缓解能力的差异。本研究利用小鼠认知障碍模型,比较95℃(水浴30 min)和121℃(灭菌锅加热30 min)热处理蛋黄脂质组分改善小鼠学习认知能力的差异。研究结果表明,相较于121℃热处理... 详细信息

为探讨不同温度处理下蛋黄脂质对小鼠学习认知能力下降的缓解能力的差异。本研究利用小鼠认知障碍模型,比较95℃(水浴30 min)和121℃(灭菌锅加热30 min)热处理蛋黄脂质组分改善小鼠学习认知能力的差异。研究结果表明,相较于121℃热处理的蛋黄脂质,95℃热处理的蛋黄脂质更有效地降低了Tau蛋白的磷酸化和Aβ1-40、GSK-3β表达,下调了促炎因子的表达,其提升小鼠的学习记忆能力的效果更好。95℃热处理蛋黄脂质中的多不饱和脂肪酸以及DHA较121℃热处理的蛋黄脂质显著增加(P<0.05)。因此,过度的加热条件,会破坏蛋品中DHA等多不饱和脂肪酸,削弱蛋黄脂质的改善认知的生物活性。本研究为蛋制品的热加工工艺的优化提供参考依据。

关键词：蛋黄脂质热处理学习和记忆

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基于分布式交互作战仿真的智能决策支持系统分析

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系统仿真学报 2002年第4期14卷 531-533页

作者：马亚龙王精业徐丙立刘永红装甲兵工程学院仿真室北京100072

在分布式交互作战仿真的环境下,论述了智能决策支持系统的需求、功能、体系结构及关键技术,并对国内外现状进行了阐述。智能决策系统是决策支持系统的发展方向。

关键词：分布式交互作战仿真智能决策支持系统数字化战场军事

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MICROSTRUCTURES OF TiAl BASED ALLOYS PREPARED BY HOT PRESSING ELEMENTAL POWDERS

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中国有色金属学会会刊：英文版 1998年第3期8卷 42-47页

作者： yong, liu Baiyun, Huang Yuehui, He bing, Wang Central South Univ of Technology Changsha China

１ＩＮＴＲＯＤＵＣＴＩＯＮＴｉＡｌｂａｓｅｄａｌｏｙｓｈａｖｅｂｅｅｎｒｅｇａｒｄｅｄａｓｐｒｏｍｉｓｉｎｇｈｉｇｈｔｅｍｐｅｒａｔｕｒｅｓｔｒｕｃｔｕｒｅｍａｔｅｒｉａｌｓ，ｆｏｒｔｈｅｉｒｈｉｇｈｓｐｅｃｉｆｉｃ... 详细信息

１ＩＮＴＲＯＤＵＣＴＩＯＮＴｉＡｌｂａｓｅｄａｌｏｙｓｈａｖｅｂｅｅｎｒｅｇａｒｄｅｄａｓｐｒｏｍｉｓｉｎｇｈｉｇｈｔｅｍｐｅｒａｔｕｒｅｓｔｒｕｃｔｕｒｅｍａｔｅｒｉａｌｓ，ｆｏｒｔｈｅｉｒｈｉｇｈｓｐｅｃｉｆｉｃｓｔｒｅｎｇｔｈ，ｒｉｇｉｄｉｔｙ...

关键词： TiAl based alloy hot press powder metallurgy

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Electro-optic tuning in ferroelectric capacitor with photonic crystal nanobeam cavity

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Science China(Information Sciences) 2025年

作者： Tongtong WANG yong ZHANG Danyang YAO Zhi JIANG Dongxin TAN Jie WEN Qiyu YANG Xuetao GAN Yan liu Yue HAO Genquan HAN State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology School of MicroelectronicsXidian University Key Laboratory of Light Field Manipulation and Information Acquisition Ministry of Industry and Information TechnologyShaanxi Key Laboratory of Optical Information Technology School of Physical Science and TechnologyNorthwestern Polytechnical University Hangzhou Institute of Technology Xidian University

Silicon photonics has provided a platform for the convergency of photonic devices and electronic circuits, facilitating the development of optical telecommunications and optical interconnects on chip[1]. As the basic building block of optical communication systems, electro-optic tuning is expected to be more compact, high bandwidth, energy efficient, and allow for CMOS-compatible fabrication in the future[2]. Resonator-based electro-optic tuning has attracted more and more interest due to the small footprint, enhanced light-matter interactions and high energy efficiency. Compared with microring and microdisk resonators, photonic crystal nanobeam cavities （PCNBCs） realize higher quality factors, stronger light-matter interactions, ultrasmall mode volume and a much larger free spectral range （FSR）[3].

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