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Large Sets of Pure Directed Triple Systems with Index λ

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Acta Mathematica Sinica,English Series 2010年第10期26卷 1899-1914页

作者： bing li fan Jun ling ZHOU Institute of Mathematics Beijing Jiaotong University Beijing 100044 P. R. China

A directed triple system of order v with index λ, briefly by DTS（v,λ）, is a pair （X, B） where X is a v-set and B is a collection of transitive triples （blocks） on X such that every ordered pair of X belongs to λ blocks of B. A simple DTS（v, λ） is a DTS（v, λ） without repeated blocks. A simple DTS（v, ）,） is called pure and denoted by PDTS（v, λ） if （x, y, z） ∈ B implies （z, y, x）, （z, x, y）, （y, x, z）, （y, z, x）, （x, z, y） B. A large set of disjoint PDTS（v, λ）, denoted by LPDTS（v, λ）, is a collection of 3（v - 2）/λ disjoint pure directed triple systems on X. In this paper, some results about the existence for LPDTS（v, λ） are presented. Especially, we determine the spectrum of LPDTS（v, 2）.

关键词： Large set directed triple system pure

The Intersection Numbers of Nearly Kirkman Triple Systems

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Acta Mathematica Sinica,English Series 2016年第12期32卷 1430-1450页

作者： bing li fan Zhong Hao JIANG Institute of Mathematics Beijing Jiaotong University

In this paper, we investigate the intersection numbers of nearly Kirkman triple ***[V] is the set of all integers k such that there is a pair of NKTS（v）s with a common uncovered collection of 2-subset intersecting in k triples. It has been established that JN[v] = {0, 1,. v（v-2）/6-6,v（v-2）/6-4,v（v-2）/6} for any integers v = 0 （mod 6） and v ≥ 66. For v ≤ 60, there are 8 cases leftundecided.

关键词： Nearly kirkman triple system parallel class frame intersection number

Study on the effect of CH_(4) dissolution on the microstructure of wax crystal in waxy crude oil

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Petroleum Science 2022年第4期19卷 1853-1865页

作者： bing-fan li Man-Ping Yang Gang liu li-Ming Zheng Chao Yang School of Vehicles and Energy Yanshan UniversityQinhuangdao066004HebeiChina University of Petroleum(East China) Shandong Provincial Key Laboratory of Oil&GasStorage and Transportation SafetyQingdao266580ShandongChina Technology Inspection Center of Shengli Oilfield SINOPECDongying257000China

In this work, the influence of the dissolution of methane(CH_(4)) gas on the wax crystal of waxy crude oil and the effect on the rheology of crude oil by dissolved CH_(4) were studied comprehensively. A self-deign high-pressure micro visualization device was developed to analyze wax crystals before and after gas dissolution. The crude oil from Shengli and Nanyang was tested by the device under various gas pressures. Results showed that the viscosity, maximum shear stress and equilibrium shear stress of Shengli crude oil decreased with the increasing pressure of the dissolved CH_(4). Due to the supersaturation of dissolved gas, the viscosity, maximum shear stress and equilibrium shear stress of Nanyang crude oil decreased initially and increased with the increasing pressure of dissolved CH_(4). The change in rheology of the dissolved gas crude oil can be a combined influence of gas pressure and dissolution mechanisms caused by CH_(4). Additionally, the wax precipitation point of Shengli crude oil decreased at the saturated dissolution of CH_(4), while Nanyang crude oil showed an increasing wax precipitation ***, the wax precipitation area, number of wax particles, and average diameter of wax crystal in both crude oils gradually decreased with dissolution. However, a saturation of CH_(4) caused a small amount of precipitation of wax crystals in Nanyang crude oil, and the small wax crystals were aggregated to form the large wax crystals. The dissolution of CH_(4) gas can affect the wax crystallization process, crystallization ability, and morphology of wax crystals that resulted in significant variation in the rheology of crude oil.

关键词： Waxy crude oil CH_(4)dissolution Wax crystal Rheology Mechanism

Thermal Error Compensation of the Wear-Depth Real-Time Detecting of Self-Lubricating Spherical Plain Bearings

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Chinese Journal of Mechanical Engineering 2018年第5期31卷 35-47页

作者： Zhan-Qi Hu Wei li Yu-lin Yang bing-li fan Hai-li Zhou Aviation Key Laboratory of Science and Technology on Generic Technology of Aviation Self-Lubricating Spherical Plain Bearing Yanshan University

The spherical plain bearing test bench is a necessary detecting equipment in the research process of self?lubricating spherical plain bearings. The varying environmental temperatures cause the thermal deformation of the wear?depth detecting system of bearing test benches and then a ect the accuracy of the wear?depth detecting data. However, few researches about the spherical plain bearing test benches can be found with the implementation of the detect?ing error compensation. Based on the self?made modular spherical plain bearing test bench, two main causes of ther?mal errors, the friction heat of bearings and the environmental temperature variation, are analysed. The thermal errors caused by the friction heat of bearings are calculated, and the thermal deformation of the wear?depth detecting sys?tem caused by the varying environmental temperatures is detected. In view of the above results, the environmental temperature variation is the main cause of the two error factors. When the environmental temperatures rise is 10.3 °C, the thermal deformation is approximately 0.01 mm. In addition, the comprehensive compensating model of the thermal error of the wear?depth detecting system is built by multiple linear regression(MLR) and time series analysis. Compared with the detecting data of the thermal errors, the comprehensive compensating model has higher fitting precision, and the maximum residual is only 1 μm. A comprehensive compensating model of the thermal error of the wear?depth detecting system is proposed, which provides a theoretical basis for the improvement of the real?time wear?depth detecting precision of the spherical plain bearing test bench.

关键词： Self?lubricating spherical plain bearing Wear depth Bearing test bench Thermal error Error compensation

Proteome analysis of round-headed and normal spermatozoa by 2-D fluorescence difference gel electrophoresis and mass spectrometry

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Asian Journal of Andrology 2009年第6期11卷 683-694页

作者： Ting-Ting liao Zhen Xiang Wen-bing Zhu li-Qing fan Institute of Human Reproduction and Stem Cell Engineering Central South University Changsha 410078 China

Globozoospermia is a severe form of teratozoospermia characterized by round-headed spermatozoa with an absent acrosome, an aberrant nuclear membrane and midpiece defects. Globozoospermia is diagnosed by the presence of 100% round-headed spermatozoa on semen analysis, and patients with this condition are absolutely infertile. The objective of this study was to investigate the differences in protein expression between human round- headed and normal spermatozoa. Two-dimensional （2-D） fluorescence difference gel electrophoresis （DIGE） coupled with mass spectrometry （MS） was used in this study. Over 61 protein spots were analysed in each paired normal/round-headed comparison, using DIGE technology along with an internal standard. In total, 35 protein spots identified by tandem mass spectrometry （MS/MS） exhibited significant changes （paired t-test, P 〈 0.05） in the expression level between normal and round-headed spermatozoa. A total of nine proteins were found to be upregulated and 26 proteins were found to be downregulated in round-headed spermatozoa compared with normal spermatozoa. The differentially expressed proteins that we identified may have important roles in a variety of cellular processes and structures, including spermatogenesis, cell skeleton, metabolism and spermatozoa motility.

关键词： differential protein globozoospermia mass spectrometry (MS) two-dimensional difference gel electrophoresis (2-D DIGE)

Mechanism by which Rab5 promotes regeneration and functional recovery of zebrafish Mauthner axons

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Neural Regeneration Research 2025年第6期20卷 1816-1824页

作者： Jiantao Cui Yueru Shen Zheng Song Dinggang fan bing Hu Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina

Rab5 is a GTPase protein that is involved in intracellular membrane trafficking. It functions by binding to various effector proteins and regulating cellular responses, including the formation of transport vesicles and their fusion with the cellular membrane. Rab5 has been reported to play an important role in the development of the zebrafish embryo;however, its role in axonal regeneration in the central nervous system remains unclear. In this study, we established a zebrafish Mauthner cell model of axonal injury using single-cell electroporation and two-photon axotomy techniques. We found that overexpression of Rab5 in single Mauthner cells promoted marked axonal regeneration and increased the number of intra-axonal transport vesicles. In contrast, treatment of zebrafish larvae with the Rab kinase inhibitor CID-1067700markedly inhibited axonal regeneration in Mauthner cells. We also found that Rab5 activated phosphatidylinositol 3-kinase(PI3K) during axonal repair of Mauthner cells and promoted the recovery of zebrafish locomotor function. Additionally, rapamycin, an inhibitor of the mechanistic target of rapamycin downstream of PI3K, markedly hindered axonal regeneration. These findings suggest that Rab5 promotes the axonal regeneration of injured zebrafish Mauthner cells by activating the PI3K signaling pathway.

关键词： axonal regeneration Mauthner cell nerve regeneration Rab5 zebrafish

The control system of intelligent wheelchair

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Journal of Measurement Science and Instrumentation 2010年第S1期1卷 69-71页

作者： Ke-yong li,bing-hui fan (Robot research center of Shandong University of Science and Technology Qingdao 266510,China) Robot Research Center Shandong University of Science and Technology

A control system of intelligent wheelchair based on spce061A and C8051 is introduced in this *** also introduces the theory of the control system,and the design of hardware and *** control system including the speech control system of SPCE061 and the keyboard control system of *** movement including marching,countermarching,speedup,slowdown,turning left,turning right,uphill and downhill were *** speech control system control based on SPCE061A and C8051 is simple,a high ratio of capability to *** system can be easily realized and enlarged.

关键词： Speech recognize SPCE061A C8051DF020

川草乌复方联合西药治疗类风湿性关节炎的有效性与安全性Meta分析

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中国中药杂志 2018年第2期43卷 227-233页

作者：张晓朦张冰李凡田志平北京中医药大学

Meta分析含川草乌中药复方联合西药治疗类风湿性关节炎（RA）的有效性与安全性,以期为临床提供RA治疗用药参考与依据。系统检索中国知网、维普、万方、中国生物医学文献数据库以及Pub Med、Cochrane library等期刊文献数据库,时间从建... 详细信息

Meta分析含川草乌中药复方联合西药治疗类风湿性关节炎（RA）的有效性与安全性,以期为临床提供RA治疗用药参考与依据。系统检索中国知网、维普、万方、中国生物医学文献数据库以及Pub Med、Cochrane library等期刊文献数据库,时间从建库截至2017年7月。依据既定的纳入标准,共获得含川草乌中药复方联合西药治疗RA的随机对照试验（RCT）8项。按照川草乌入药种类不同,分为川乌亚组（6RCTs）、草乌亚组（1RCT）、川草乌叠加亚组（1RCT）。结果显示,较西医常规用药,联合应用含川乌、草乌、川草乌叠加的中药复方均可提高RA临床疗效总有效率,结果分别为（6RCTs,RR=1.19,95%CI[1.10,1.28],P〈0.000 01）,（1RCT,RR=1.43,95%CI[1.18,1.73],P=0.000 2）,（1RCT,RR=1.27,95%CI[1.02,1.58],P=0.03）。联合用药对患者关节肿胀数、晨僵时间、双手握力以及血沉、C反应蛋白、类风湿因子等均有改善作用,但对关节压痛数的作用不显著。同时,纳入RCT中联合应用川草乌不良反应/事件（ADR/ADE）34例,常规西药治疗ADR/ADE 86例,川乌、川草乌叠加用药亚组ADR/ADE发生率更低,草乌亚组则与常规西药对照组无异。现有临床研究显示,含川草乌中药复方与西药联合应用治疗RA的疗效与安全性均较单独应用西药具有一定的优势,但受RCT质量不高、缺少大规模多中心研究等局限,该结果还有待临床进一步验证。

关键词：川草乌类风湿性关节炎有效性安全性 Meta分析

多孔金属有机框架材料在甲烷存储与捕集中的研究进展及挑战

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新型炭材料 2021年第3期36卷 468-496页

作者：李东泽陈雷刘刚袁子云李秉繁张旭魏甲强中国石油大学(华东)山东省油气储运安全省级重点实验室山东青岛266580

在全球向可持续低碳经济转型的过程中,作为两大低碳能源技术,甲烷储存和甲烷捕集都面临着同样的挑战,即缺乏高效的吸附剂。MOFs(metal-organic frameworks)材料具有极高的比表面积、孔隙率和可调节的孔隙结构,在气体吸附储存领域拥有极... 详细信息

在全球向可持续低碳经济转型的过程中,作为两大低碳能源技术,甲烷储存和甲烷捕集都面临着同样的挑战,即缺乏高效的吸附剂。MOFs(metal-organic frameworks)材料具有极高的比表面积、孔隙率和可调节的孔隙结构,在气体吸附储存领域拥有极大的潜在应用价值。本文首先介绍了MOFs的结构设计和合成方法,综述并强调了MOFs材料在CH_4储存与捕集方面的研究进展及面临的问题。在CH_4高压储存方面,从体积吸附量和质量吸附量两个目标出发,介绍了目前MOFs材料储存CH_4的研究现状;在CH_4常压捕集方面,重点强调了CH_4/N_2和CO_2/CH_4分离技术和CH4捕集技术。最后,对利用MOFs材料实现高效CH_4储存和捕集存在的问题和挑战进行了分析和展望。

关键词：金属有机框架甲烷吸附储存捕集