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Microstructure evolution of TiB_（2） particle-reinforced 7075 Al alloy slurry in semisolid state with different holding time

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Rare Metals 2016年第11期35卷 858-862页

作者： gui-Sheng Gan bin Yang School of Materials Science and Engineering Chongqing University of Technology State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing

TiB_2particle-reinforced 7075 Al alloy was synthesized to investigate the effect of TiB_2 particles on microstructure of semisolid 7075 Al alloy slurry. The mean grain size and shape factor of 3 wt% TiB_2/7075 composite could reach 92 lm and 0.64 at 630 ℃ for 23 min,respectively, and for 6 wt% TiB_2/7075 composite, they are100 lm and 0.64 at 630 ℃ for 33 min. The microstructure evolution for TiB_2/7075 composites in semisolid state includes three-stage process. a-Al begins to nucleate and grow up into rosette grains due to a low degree of supercooling at first. Then rosette grains begin to fuse or grow up at different rates. Finally, the dissolution rate and the growth rate of α-Al reach equilibrium.

关键词： Particle-reinforced 7075 Al alloy Semisolid state Microstructure evolution

Identification and functional characterization of an odorant receptor in pea aphid,Acyrthosiphon pisum

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Insect Science 2019年第1期26卷 58-67页

作者： Rui-bin Zhang Yang Liu Shan-Chun Yan gui-Rong wang The College of Forestry Northeast Forestry UniversityHarbinChina State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijingChina

The sensitive olfactory system is necessary for survival of *** receptors (ORs)are located on the dendrites of olfactory receptor neurons and play a critical role in odor *** ORs are functionally analyzed via heterologous expression in a Xenopus oocyte system using a two-electrode voltage-clamp (TEVC)electrophysiological ***,we have identified a novel OR in the pea aphid,Acyrthosiphon pisum,then we cloned and named it *** analyzed the ApisOR4 tissue expression patterns and found expression only in antennae *** functional analysis using TEVC revealed that ApisOR4 is broadly tuned to eight volatiles,which elicit electrophysiological response in pea aphid *** study provides an initial functional analysis of aphid ORs and identifies candidate volatiles to be used in developing new strategies for aphid control.

关键词： Acyrthosiphonpisum electroantennogram heterologous expression odorant receptor

Relationship between the expression of IP-10 and IP-10 mRNA in peripheral blood and HBV DNA level in patients with cirrhosis

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Hepatobiliary & Pancreatic Diseases International 2010年第3期9卷 280-286页

作者： wang, Jian wang, Ping-Ping Xiang, gui-Ju Hu, Xiao-bin Anhui Univ Sci & Technol Coll Med Dept Aetiol & Immunol Huainan 232001 Peoples R China Second Miners Hosp Huainan Xinhua Hosp Huainan Dept Infect Dis Huainan 232052 Peoples R China

BACKGROUND: Post-hepatitic cirrhosis is regarded as common and severe form of liver damage. Interferon gamma-inducible protein 10 (IP-10), a member of the non-ELR (glutamic-leucine-arginine) motif CXC chemokine family, has recently been shown to recruit and activate specific subsets of leukocytes to sites of inflammation or an immune response during the development of hepatic cirrhosis. However, the effects of IP-10 and IP-10 mRNA on inflammatory infiltration at local sites and in the peripheral blood of patients with post-hepatitic cirrhosis as well as their relationship with viral load are still poorly defined. This study aimed to detect the relationship between the expression of IP-10 in serum, IP-10 mRNA in peripheral blood mononuclear cells (PBMCs), and the levels of HBV DNA in the serum of patients, and to explore their role in the pathogenesis of cirrhosis. METHODS: Typical patients with cirrhosis after HBV infection were selected, and their serum IP-10 concentrations were evaluated with ELISA, the content of IP-10 mRNA in PBMCs was measured by real-time PCR, and the load of HBV DNA in serum and PBMCs was assessed by semi-quantitative analysis of gel imaging. RESULTS: The levels of IP-10 in serum and IP-10 mRNA in PBMCs of patients with cirrhosis were 299.9 +/- 77.2 pg/ml and 0.7500 +/- 0.1495, respectively. They were higher than those of controls (P1) to 343.0 +/- 80.3 pg/ml and 0.8465 +/- 0.1528, respectively. The levels of IP-10 in serum and IP-10 mRNA in PBMCs were clearly correlated with the load of HBV DNA (P1). CONCLUSIONS: The levels of IP-10 and IP-10 mRNA in the peripheral blood of patients with cirrhosis increase are closely correlated with the load of HBV DNA in serum, and play a key role in the progression of post-hepatitic cirrhosis. (Hepatobiliary Pancreat Dis Int 2010; 9: 280-286)

关键词： hepatic cirrhosis interferon gamma-inducible protein 10 mRNA HBV DNA peripheral blood mononuclear cells

Construction of three stereocenters via hydrogenative desymmetrization of 2,2,5-trisubstituted cyclohexane-1,3-diones

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Science China Chemistry 2021年第2期64卷 232-237页

作者： Yi-Xuan Ding Zhou-Hao Zhu Han wang Chang-bin Yu Yong-gui Zhou State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

A Ru-catalyzed hydrogenative desymmetrization of 2,2,5-trisubstituted cyclohexane-1,3-diones was developed for construction of three stereocenters including two coherent and discontiguous chiral centers and a chiral quaternary carbon with excellent enantio-and *** synthesis of four stereoisomers could be conducted with high *** desymmetrization could be achieved at gram scale without loss of reactivity and optical purity,and a formal synthesis of bioactive molecule(-)-isocelorbicol was completed.

关键词： desymmetrization hydrogenation 1,3-cyclohexanediones three stereocenters chiral quaternary carbon

New Upper Bounds on Linear Coloring of Planar Graphs

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Acta Mathematica Sinica,English Series 2012年第6期28卷 1187-1196页

作者： bin LIU gui Zhen LIU Department of Mathematics Ocean University of China School of Mathematics Shandong University

A proper vertex coloring of a graph G is linear if the graph induced by the vertices of any two color classes is the union of vertex-disjoint paths. The linear chromatic number lc（G） of the graph G is the smallest number of colors in a linear coloring of G. In this paper, it is proved that every planar graph G with girth g and maximum degree A has （1） lc（G） ≤ △ ＋ 21 if △ ≥ 9; （2） lc（G） ≤[△/2]＋ 7 if g≥5; （3） lc（G） ≤ [△/2]＋2ifg≥7and△ ≥7.

关键词： Linear coloring planar graph girth

Expression profiles and functional prediction of ionotropic receptors in Asian corn borer, Ostrinia furnacalis(Lepidoptera:Crambidae)

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Journal of Integrative Agriculture 2022年第2期21卷 474-485页

作者： ZHANG Yu YANG bin YU Jie PANG Bao-ping wang gui-rong Research Center for Grassland Entomology Inner Mongolia Agricultural UniversityHohhot 010018P.R.China State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193P.R.China Guangdong Laboratory of Lingnan Modern Agriculture(Shenzhen Branch)/Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs/Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural SciencesShenzhen 518116P.R.China

Genes involved in chemosensation are essential for odorant-mediated insect behaviors. Odorant receptors(ORs) bind and respond to pheromones and plant volatiles, regulating insect behaviors such as mating and host-plant selection, while ionotropic receptors(IRs), which are present at lower levels in insects than ORs, influence ion channels, especially in agricultural pests. Asian corn borer, Ostrinia furnacalis, is the main pest of maize that causes huge economic losses in Asia. Twenty-one Ofur IRs have been identified, but none has been characterized. In this study, tissue-specific expression profiling, phylogenetic analysis, and electroantennography(EAG) analysis were applied to characterize the evolution, expression, and the potential function of Ofur IRs. It was found that 20 Ofur IRs were highly expressed in the antennae, except for Ofur IR75p3, whereas 10 and nine Ofur IRs were highly expressed in the proboscis and genitalia, respectively, indicating that these Ofur IRs were functionally associated with feeding and oviposition. EAG results showed that seven acids elicited responses in the antennae of O. furnacalis and that 2-oxopentanoic acid displayed a significant femalebiased response. Combined with the phylogenetic analysis, 10 Ofur IRs in clade 4 were roughly predicted to be candidate receptors for 2-oxopentanoic acid and other tested acids. These results provide basic information about Ofur IRs and may help advance the knolwedge on the olfactory system of O. furnacalis.

关键词： ionotropic receptors Ostrinia furnacalis phylogenetic analysis EAG qRT-PCR

Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii

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Chinese Chemical Letters 2015年第3期26卷 313-316页

作者： Peng Zhang Xiao-Ming Li Jia-Ning wang Xin Li bin-gui wang Key Laboratory of Experimental Marine Biology Institute of OceanologyChinese Academy of Sciences University of Chinese Academy of Sciences

Two new prenylated indole alkaloids,namely,dihydrocarneamide A（1） and iso-notoamide B（2）,were isolated from the marine-derived endophytic fungus Paecilomyces variotii *** structures of these metabolites were determined based on comprehensive spectral analysis,together with chiral HPLC analysis of the acidic *** other prenylated indole alkaloids such as asperparalines,notoamides,and versicolamides,compounds 1 and 2 are the rare examples of C-5 prenylation,forming the fused dimethyldihydropyran ring at C-5 and C-6 of the indole *** cytotoxic activity of the isolated compounds was evaluated.

关键词： Paecilomyces alkaloids indole endophytic fused fungus cytotoxic COSY Penicillium acidic

Microstructure and physical properties of steel-ladle purging plug refractory materials

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International Journal of Minerals,Metallurgy and Materials 2017年第2期24卷 186-193页

作者： bin Long gui-ying Xu Buhr Andreas School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China Almatis Qingdao Co. Ltd. Qingdao 266071 China Almatis GmbH Frankfurt 60528 Germany

Three different castables were prepared as steel-ladle purging-plug refractory materials： corundum-based low-cement castable （C-LCC）, corundum-spinel-based low-cement castable （C-S-LCC）, and no-cement corundum-spinel castable （C-S-NCC）（hydratable alu- mina p-A1203 bonded）. The properties of these castables were characterized with regard to water demand/flow ability, cold crushing strength （CCS）, cold modulus of rupture （CMoR）, permanent linear change （PLC）, apparent porosity, and hot modulus of rupture （HMoR）. The re- sults show the CCS/CMoR and HMoR of C-LCC and C-S-LCC are greater than those of the castable C-S-NCC. According to the micro- structure analysis, the sintering effect and the bonding type of the matrix material differ among the three castables. The calcium hexaluminate （CA6） phase in the matrix of C-LCC enhances the cold and hot mechanical strengths. In the case of C-S-LCC, the CA6 and 2CaO·2MgO·14A12O3（C2MEA14） ternary phases generated from the matrix can greatly increase the cold and hot mechanical strengths. In the case of the no-cement castable, sintering becomes difficult, resulting in a lower mechanical strength.

关键词： refractory materials purging plugs castable physical properties microstructure

Rare pattern of Maisonneuve fracture:A case report

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World Journal of Clinical Cases 2022年第14期10卷 4684-4690页

作者： bin Zhao Nan Li Hong-bin Cao gui-Xin wang Jin-Quan He Department of Foot and Ankle SurgeryⅠ Tianjin HospitalTianjin 300211China

BACKGROUND Maisonneuve fracture is a special type of ankle fracture that consists of proximal fibular fracture,a lesion of the inferior tibiofibular syndesmotic complex(interosseous ligament,anterior inferior tibiofibular ligament and posterior inferior tibiofibular ligament),and injury of the medial structure of the ankle(deltoid ligament tear or medial malleolar fracture).The accepted mechanism of Maisonneuve fracture is pronation external rotation according to the Lauge-Hansen *** this paper,we report a rare pattern of Maisonneuve fracture,which has the characteristics of both pronation external rotation ankle fracture and supination adduction ankle *** SUMMARY A 31-year-old female patient accidentally sprained her right ankle while walking 5 d before hospitalization in our *** patient was initially missed in other hospitals and later rediagnosed in our outpatient ***-length radiographs of the lower leg revealed proximal fibula fracture,inferior tibiofibular joint separation,and medial malleolar fracture involving the posterior malleolus,which was also revealed on computed tomography *** resonance imaging revealed rupture of the anterior inferior tibiofibular ligament and anterior talofibular *** diagnosed a rare pattern of Maisonneuve fracture with proximal fibular fracture,inferior tibiofibular joint separation,medial malleolar fracture and ruptures of the anterior inferior tibiofibular ligament and anterior talofibular *** patient underwent open reduction and internal fixation in our hospital.A 6-mo postoperative follow-up confirmed a good clinical *** To our knowledge,this rare pattern of Maisonneuve fracture has not been previously *** possible mechanism of injury is supination adduction combined with pronation external *** analysis of the injury mechanism of Maisonneuve fracture is of great clinical significance and can better guide clinical treatm

关键词： Ankle fracture Maisonneuve fracture Mechanism analysis Pronation external rotation Supination adduction Case report