检索结果-南通市图书馆

Bioprocess inspired formation of calcite mesocrystals by cation-mediated particle attachment mechanism

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2023年第4期10卷 159-168页

作者： Qihang Wang bicheng yuan Wenyang Huang Hang Ping Jingjing Xie Kun Wang Weimin Wang Zhaoyong Zou Zhengyi Fu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Hubei Longzhong Laboratory

Calcite mesocrystals were proposed, and have been widely reported, to form in the presence of polymer additives via oriented assembly of nanoparticles. However, the formation mechanism and the role of polymer additives remain elusive. Here, inspired by the biomineralization process of sea urchin spine comprising magnesium calcite mesocrystals, we show that calcite mesocrystals could also be obtained via atachment of amorphous calcium carbonate(ACC) nanoparticles in the presence of inorganic zinc ***, we demonstrate that zinc ions can induce the formation of temporarily stabilized amorphous nanoparticles of less than 20 nm at a significantly lower calcium carbonate concentration as compared to pure solution, which is energetically beneficial for the atachment and occlusion during calcite growth. The cation-mediated particle atachment crystallization significantly improves our understanding of mesocrystal formation mechanisms in biomineralization and offers new opportunities to bioprocess inspired inorganic ions regulated materials fabrication.

关键词： nonclassical crystallization mesocrystal calcium carbonate zinc ion particle attachment

A rare case of easily misdiagnosed primary mucoepidermoid carcinoma of the liver

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2022年第3期9卷 582-584页

作者： Fusheng Liu bicheng Wang Zhonglin Zhang Yufeng yuan Haitao Wang Department of Hepatobiliary&Pancreatic Surgery Zhongnan Hospital of Wuhan UniversityWuhanHubei 430071PR China Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary&Pancreatic Diseases of Hubei Province WuhanHubei 430030PR China Department of Pathology Zhongnan Hospital of Wuhan UniversityWuhanHubei 430062PR China

To the editor,Mucoepidermoid carcinoma(MEC)is a common malignancy of the salivary glands,which account for approximately 30%of all malignant salivary gland neoplasms that originate in both the major and minor glands.1 But it is relatively rare at other organs,extremely rare in the hepatobiliary *** the best of our knowledge,since primary MEC of the liver was first reported in 1971,2 no more than 20 cases have been reported worldwide.

关键词： neoplasms organs liver

Lymphatic vessel:origin,heterogeneity,biological functions,and therapeutic targets

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第2期9卷 442-478页

作者： Zhaoliang Hu Xushi Zhao Zhonghua Wu bicheng Qu Minxian yuan Yanan Xing Yongxi Song Zhenning Wang Department of Surgical Oncology and General Surgery The First Hospital of China Medical UniversityKey Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors(China Medical University)Ministry of Education155 North Nanjing StreetHeping DistrictShenyang 110001China

Lymphatic vessels,comprising the secondary circulatory system in human body,play a multifaceted role in maintaining homeostasis among various tissues and *** are tasked with a serious of responsibilities,including the regulation of lymph absorption and transport,the orchestration of immune surveillance and *** vessel development undergoes a series of sophisticated regulatory signaling pathways governing heterogeneous-origin cell populations stepwise to assemble into the highly specialized lymphatic vessel ***,as defined by new lymphatic vessels sprouting from preexisting lymphatic vessels/embryonic veins,is the main developmental mechanism underlying the formation and expansion of lymphatic vessel networks in an ***,abnormal lymphangiogenesis could be observed in many pathological conditions and has a close relationship with the development and progression of various *** studies have revealed a set of lymphangiogenic factors and cascades that may serve as the potential targets for regulating abnormal lymphangiogenesis,to further modulate the progression of ***,an increasing number of clinical trials have demonstrated the promising interventions and showed the feasibility of currently available treatments for future clinical *** lymphangiogenic promoters or inhibitors not only directly regulates abnormal lymphangiogenesis,but improves the efficacy of diverse *** conclusion,we present a comprehensive overview of lymphatic vessel development and physiological functions,and describe the critical involvement of abnormal lymphangiogenesis in multiple ***,we summarize the targeting therapeutic values of abnormal lymphangiogenesis,providing novel perspectives for treatment strategy of multiple human diseases.

关键词： therapeutic origin specialized

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于词典优化与空间一致性度量的目标检索

计算机研究与发展 2016年第5期53卷 1043-1052页

作者：赵永威周苑李弼程武警工程大学电子技术系西安710000 河南工程学院计算机学院郑州451191 解放军信息工程大学信息系统工程学院郑州450002

基于视觉词典模型(bag of visual words model,BoVWM)的目标检索存在时间效率低、词典区分性不强的问题,以及由于空间信息的缺失及量化误差等导致的视觉语义分辨力不强的问题.针对这些问题,提出了基于词典优化与空间一致性度量的目标检... 详细信息

基于视觉词典模型(bag of visual words model,BoVWM)的目标检索存在时间效率低、词典区分性不强的问题,以及由于空间信息的缺失及量化误差等导致的视觉语义分辨力不强的问题.针对这些问题,提出了基于词典优化与空间一致性度量的目标检索方法.首先,该方法引入E2LSH(exact Euclidean locality sensitive hashing)过滤图像中的噪声和相似关键点,提高词典生成效率和质量;然后,引入卡方模型(chi-square model,CSM)移除词典中的视觉停用词增强视觉词典的区分性;最后,采用空间一致性度量准则进行目标检索并对初始结果进行K-近邻(K-nearest neighbors,K-NN)重排序.实验结果表明:新方法在一定程度上改善了视觉词典的质量,增强了视觉语义分辨能力,进而有效地提高目标检索性能.

关键词：目标检索视觉词典模型精确欧氏位置敏感哈希空间一致性度量卡方模型

Construction and Validation of an Urban Area Flow and Dispersion Model on Building Scales

在线全文

学校读者我要写书评

暂无评论

Acta meteorologica Sinica 2013年第6期27卷 923-941页

作者：陈笔澄刘树华缪育聪王姝李源 Department of Atmospheric and Oceanic Sciences School of PhysicsPeking University

This paper presents a numerical model that simulates the wind fields, turbulence fields, and dispersion of gaseous substances in urban areas on building to city block scales. A Computational Fluid Dynamics（CFD） approach using the steady-state, Reynolds-Averaged Navier-Stokes（RANS） equations with the standard k-ε turbulence model within control volumes of non-uniform cuboid shapes has been employed. Dispersion field is computed by solving an unsteady transport equation of passive scalar. Another approach based on Gaussian plume model is used to correct the turbulent Schmidt number of tracer, in order to improve the dispersion simulation. The experimental data from a wind tunnel under neutral conditions are used to validate the numerical results of velocity, turbulence, and dispersion fields. The numerical results show a reasonable agreement with the wind tunnel data. The deviation of concentration between the simulation with corrected turbulent Schmidt number and the wind tunnel experiments may arise from 1） imperfect point sources, 2） heterogeneous turbulent difusivity, and 3） the constant turbulent Schmidt assumption used in the model.

关键词： urban areas flow and dispersion computational fluid dynamics RANS equation k-ε model turbulent Schmidt number

Immune mediated support of metastasis:Implication for bone invasion

在线全文

学校读者我要写书评

暂无评论

Cancer Communications 2024年第9期44卷 967-991页

作者： Zengfeng Xin Luying Qin Yang Tang Siyu Guo Fangfang Li yuan Fang Gege Li Yihan Yao Binbin Zheng bicheng Zhang Dang Wu Jie Xiao Chao Ni Qichun Wei Ting Zhang Department of Orthopedic Surgery Second Affiliated HospitalZhejiang University School of MedicineZhejiang UniversityHangzhouZhejiangP.R.China Cancer Institute(Key Laboratory of Cancer Prevention and Intervention National Ministry of Education)Second Affiliated HospitalZhejiang University School of MedicineZhejiang UniversityHangzhouZhejiangP.R.China Department of Radiation Oncology Second Affiliated HospitalZhejiang University School of MedicineZhejiang UniversityHangzhouZhejiangP.R.China Department of Respiratory Medicine Ningbo Hangzhou Bay HospitalNingboZhejiangP.R.China Department of Orthopedic Surgery Second Affiliated Hospital(Jiande Branch)Zhejiang University School of MedicineHangzhouZhejiangP.R.China Department of Breast Surgery Second Affiliated HospitalZhejiang University School of MedicineZhejiang UniversityHangzhouZhejiangP.R.China

Bone is a common organ affected by metastasis in various advanced cancers,including lung,breast,prostate,colorectal,and *** a patient is diagnosed with bone metastasis,the patient’s quality of life and overall survival are significantly reduced owing to a wide range ofmorbidities and the increasing difficulty of *** studies have shown that bone metastasis is closely related to bone microenvironment,especially bone immune ***,the effects of various immune cells in the bone microenvironment on bone metastasis remain ***,we described the changes in various immune cells during bone metastasis and discussed their related ***,adipocytes,and other non-immune cells closely related to bone metastasis were also *** review also summarized the existing treatment methods and potential therapeutic targets,and provided insights for future studies of cancer bone metastasis.

关键词： bone metastasis bone microenvironment cancer immune cell therapy

基于依存句法分析与分类器融合的触发词抽取方法

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

计算机应用研究 2016年第5期33卷 1407-1410页

作者：高源席耀一李弼程解放军信息工程大学信息系统工程学院郑州450001

事件检测与分类是事件抽取的关键环节,触发词抽取是完成事件检测与分类的主流方法。提出了一种事件触发词抽取方法,该方法针对单一触发词抽取方法没有充分利用依存句法分析信息且召回率不高的问题,通过综合利用依存句法分析信息和其他... 详细信息

事件检测与分类是事件抽取的关键环节,触发词抽取是完成事件检测与分类的主流方法。提出了一种事件触发词抽取方法,该方法针对单一触发词抽取方法没有充分利用依存句法分析信息且召回率不高的问题,通过综合利用依存句法分析信息和其他信息抽取触发词—实体描述对的方法来提高触发词抽取的召回率,然后将触发词—实体描述对抽取结果与单一触发词抽取结果相融合以避免召回率提高所带来的准确率下降问题。在ACE2005中文语料上进行实验,该方法在事件检测与分类任务中取得较好效果,F值分别达到了69.0%和66.2%。

关键词：事件抽取触发词依存句法分析触发词—实体描述对支持向量机分类器融合

急性肾损伤在急性心肌梗死患者短期和长期预后中的预测作用

在线全文

学校读者我要写书评

暂无评论

中华肾脏病杂志 2016年第11期32卷 813-820页

作者：孙妍蓓陶源刘必成杨敏苏州大学附属第三医院常州市第一人民医院肾脏科常州213000 东南大学附属中大医院肾脏科南京210009

目的评估急性肾损伤（AKI）对急性心肌梗死（AMI）患者短期（30d内）和长期（30d-5年内）预后的预测作用。方法回顾分析2008年12月1日至2012年12月31日在苏州大学附属第三医院诊断AMI患者（共计1371例）的临床资料，根据KDIGO指南推荐... 详细信息

目的评估急性肾损伤（AKI）对急性心肌梗死（AMI）患者短期（30d内）和长期（30d-5年内）预后的预测作用。方法回顾分析2008年12月1日至2012年12月31日在苏州大学附属第三医院诊断AMI患者（共计1371例）的临床资料，根据KDIGO指南推荐标准定义AKI及分级。将30d内和30d～5年内AMI患者的死亡组和非死亡组进行比较。不同AKI分期AMI患者进行比较，及Kaplan-Meier曲线分析其生存率。采用COX多因素回归分析影响AMI患者30d内和30d-5年内死亡的因素。结果30d内和30d～5年内死亡组AMI患者AKI患病率均高于非死亡组（30d内为72．7％比27．4％，P〈0．001；30d-5年内为36．3％比26．2％，P=0．013）；且两组KDIGOAKI分级分布不同（30d内P〈0．001，30d～5年内P=0．002）。AMI患者有410例（29．9％）并发AKI，30d和30d～5年的病死率分别为5．6％（77／1371）和11．3％（146／1294）。AKI—Ⅰ期、AKI-Ⅱ期、AKI-Ⅲ期组AMI患者全因病死率及心血管病死率均高于非AKI组（均P〈0．001），AKI-Ⅲ期组尤为显著。脑卒中病史（HR=3．122，P=0．012）、AKI分期（AKI—Ⅰ期：HR=3．034，P=0．028；AKI-Ⅱ期：HR=7．832，P〈0．001；AKI—Ⅲ期：HR=9．919，P〈0．001）、B．受体阻滞剂的使用（HR=0．591，P=0．040）是AMI患者30d内死亡的独立影响因素；年龄（HR=1．061，P〈0．001）、血浆白蛋白（HR=0．943，P=0．023）、AKI—Ⅲ期（职=3．944，P=0．007）、β-受体阻滞剂的使用（HR=0．660，P=0．041）和PCI术（HR=0．256，P〈0．001）为AMI患者30d-5年内的死亡的独立预测因素。在随访30d和随访30d～5年中AKI伴或不伴基线。肾功能下降均为AMI患者死亡的独立预测因素（均P〈0．05）。结论无论基线。肾功能水平是否下降，AKI与AMI患者短期和长期的全因死亡风险均密切相关。且AKI越严重，AMI患者短期死亡风险越高。

关键词：心肌梗死肾功能不全,急性死亡率

基于355 nm激光在硬脆材料的表面标识研究

在线全文

学校读者我要写书评

暂无评论

应用激光 2024年第6期44卷 112-118页

作者：陈媛李必成王军馥上海市激光技术研究所有限公司上海200233 上海激光直接物标溯源工程技术研究中心上海200233 上海自然博物馆(上海科技馆分馆)藏品保护研究中心上海200041

针对透明玻璃既要满足玻璃的装饰性,也要满足对产品进行赋码追溯的高质量图形标识的需求,采用紫外纳秒激光源在常见透明玻璃材质(高硼硅玻璃、石英玻璃)表面进行激光直接标识的工艺研究。通过改变激光工艺参数来定量研究激光累计脉冲能... 详细信息

针对透明玻璃既要满足玻璃的装饰性,也要满足对产品进行赋码追溯的高质量图形标识的需求,采用紫外纳秒激光源在常见透明玻璃材质(高硼硅玻璃、石英玻璃)表面进行激光直接标识的工艺研究。通过改变激光工艺参数来定量研究激光累计脉冲能量密度、峰值功率密度以及激光脉冲扫描方式对标识区域的完整性、粗糙度以及烧蚀深度的影响效果,从而寻找适合玻璃材料表面激光标识的工艺窗口。

关键词：紫外纳秒玻璃完整性粗糙度烧蚀深度