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Chinese Physics Letters 2007年第8期24卷 2245-2248页

作者： M. singh P. Aghamkar P. K. Sen Department of Applied Physics Guru Jambheshwar University of Science and Technology Hisar-125001 India Department of Applied Physics S.G.S. Institute of Technology and Science 23-Park Road Indore-452003 India

Using the hydrodynamic model of semiconductor plasmas, we perform an analytical investigation of stimulated Raman scattering （SITS） of an electromagnetic pump wave in a transversely magnetized weakly polar semicon- ductor arising from electron-density perturbations and molecular vibrations of the medium both produced at the longitudinal optical phonon frequency. Assuming that the origin of SItS lies in the third-order susceptibility of the medium, we investigate the growth rate of Stokes mode. The dependence of stimulated Raman gain on the external dc magnetic field strength and free carrier concentration is reported. The possibility of the occurrence of optical phase conjugation via SItS is also studied. The steady-state Raman gain is found to be greatly enhanced by the presence of the strong external dc magnetic field.

关键词： Stimulated Raman Scattering Weakly Polar Semiconductor

Monitoring of TDS and conductivity in groundwater in the seismically active region in NW Himalayas,India

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Earthquake Science 2010年第3期23卷 295-299页

作者： Arvind Kumar Surinder singh Bikramjit singh Bajwa Sandeep Mahajan Rajeev Kalia Sunil Dhar Department of Physics Guru Nanak Dev University Department of Geology Govt.CollegeDharamsala

The earthquake precursors and earthquake prediction are the burning issue among the community of earth scientists and engineers. Studies of earthquake precursory phenomena since the last several decades have shown that significant geophysical and geochemical changes may occur prior to intermediate and large earthquakes （Hartmann and Levy, 2005; Yang et al, 2005; Einarsson et al, 2008; Italiano et al, 2008; Kumar et al, 2009）. Among the more intensely investigated geochemical phenomena there have been changes in the concentrations of dissolved ions and gases in groundwater as well as variations in the concentrations of crustal and mantle volatiles in ground gases.

关键词： TDS (total dissolved solids) conductivity earthquake precursor NW Himalayas

Impact of irrigation regimes on regeneration and growth of Prosopis cineraria in arid areas of Indian Thar

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Forestry Studies in China 2012年第4期14卷 320-322页

作者： Jabrinder singh Mukul BISHNOI Department of Applied Sciences HCTM Technical Campus Department of Environmental Sciences and Engineering Guru Jambheshwar University of Science and Technology

An experiment was initiated in 2008 to evaluate the impact of irrigation regimes on germination and growth patterns of seedlings of Prosopis cineraria in the arid areas of Thar, India. Seeds collected from dried pods of P cineraria were sown in polybags placed in nursery beds. Different irrigation regimes were provided to different beds and data regarding germination and growth were recorded to study natural regeneration. The study revealed that irrigation regimes significantly affected the germination and growth of P cineraria under nursery conditions. The germination rate declined as the irrigation regime shifted from a daily to a fortnightly ba- sis. Height of the seedlings also declined with a decrease in the intensity of irrigation. Thus, it can be concluded that germination and growth of seedlings of P cineraria under nursery conditions can be enhanced by providing irrigation at regular intervals.

关键词： germination growth irrigation regeneration Prosopis cineraria

Efficient Clustering and Simulated Annealing Approach for Circuit Partitioning

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Journal of Shanghai Jiaotong university(Science) 2011年第6期16卷 708-712页

作者： SANDEEP singh Gill RAJEEVAN Chandel ASHWANI Kumar Chandel Department of Electronics and Communication Engineering Guru Nanak Dev Engineering College National Institute of Technology

Circuit net list bipartitioning using simulated annealing technique has been proposed in the *** method converges asymptotically and probabilistically to global *** circuit net list is partitioned into two partitions such that the number of interconnections between the partitions is *** proposed method begins with an innovative clustering technique to obtain a good initial *** obtained show the versatility of the proposed method in solving non polynomial hard problems of circuit net list partitioning and show an improvement over those available in literature.

关键词： cut size non polynomial hard partitioning simulated annealing interconnections very large scale integration(VLSI) design

Transient photoconductivity in a-(Se80Te20)100-xAgx（0≤x≤4） thin films

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Progress in Natural Science:Materials International 2012年第5期22卷 386-391页

作者： D.singh S.Kumar R.Thangaraj Semiconductors Laboratory Department of PhysicsGuru Nanak Dev UniversityAmritsarPunjab 143005India

Bulk material of(Se80Te20)100-xAgx(0≤x≤4) system was prepared by using a conventional melt quenching *** films of a-(Se80Te20)100-xAgx(0≤x≤4) were deposited by the vacuum evaporation technique at a base pressure of 10-4 mbar onto well-cleaned glass *** dependence of electrical conductivity in the temperature range of 263-333 K has been *** is increase in the value of conductivity with increase in temperature as well as with Ag *** measurements of intensity dependence of photoconductivity show that the photoconductivity increases with intensity as a power law where the power is found to be between 0.5 and 1.0,representing the continuous distribution of *** and decay of photocurrent with time at room temperature at different light intensities for(Se80Te20)98Ag2 thin film samples have also been *** results have been explained on the basis of the Dember voltage and interaction between photoexcited holes and the trapped electrons on the surface.

关键词： Chalcogenides Se-Te-Ag system Transient photoconductivity

siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin

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World Journal of Gastroenterology 2012年第31期18卷 4127-4135页

作者： Md.Raghibul Hasan Shyam singh Chauhan Rinu Sharma Ranju Ralhan Department of Biochemistry All India Institute of Medical SciencesNew Delhi 110029India Department of Biotechnology School of BiotechnologyGuru Gobind Singh Indraprastha UniversityNew Delhi 110075India Department of Otolaryngology-Head and Neck Surgery Joseph and Mildred Sonshine Family Centre for Head and Neck DiseasesMount Sinai HospitalTorontoON M5G 1X5Canada Department of Pathology and Laboratory Medicine Alex Simona Shnaider Laboratory for Molecular OncologyMount Sinai HospitalTorontoON M5G 1X5Canada

AIM： To determine the functional significance of TC21 in esophageal squamous cell carcinoma （ESCC）. METHODS： TC21 siRNA transfection was carried out using Hyperfectamine to knock down TC21, and tran- scripts were analyzed by reverse transcription-poly- merase chain reaction and protein by Western *** demonstrated the effect of TC21 downregulation of cell signaling in esophageal cancer cells by assess- ing the phosphorylation status of its downstream tar- gets, phosphoinositide 3-kinase （PI3K）, phosphatase and tensin homolog （PTEN）, protein kinase B （pAl〈t）, nuclear factor-KB （NF-~B） and cyclinD1 using specific antibodies. Cell survival analysis after cisplatin treat- ment was carried out by cell viability assay and cell cycle analysis using flow cytometry. RESULTS： TC21 knockdown in human ESCC cell line TEl3 cells, showed only a marginal increase （14.2%） in cell death compared with control cells. The expres- sions of the signaling proteins PI3K and pAkt, transcrip- tion factor NF-KB, and cell cycle protein cyclin D1 were markedly decreased in response to TC21 downregula- tion, whereas the level of pPTEN, an antagonist of PI3K, was increased. In addition, we evaluated the potential of TC21 as a putative target for sensitizing ESCC cells to the chemotherapeutic agent cisplatin. Increased cell death （38.4%） was observed in cells treated with cis- platin after TC21 knockdown compared with cells which were treated with cisplatin alone （20% cell death）. CONCLUSION： Results suggest that TC21 mediates its effects via the PI3K-Akt pathway, NF-KB and cyclin D1, and enhances chemoresistance in esophageal cancer cells.

关键词： TC21 Esophageal squamous cell carci-noma siRNA Cisplatin Chemosensitivity

Fruit Image Classification Using Deep Learning

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Computers, Materials & Continua 2022年第6期71卷 5135-5150页

作者： Harmandeep singh Gill Osamah Ibrahim Khalaf Youseef Alotaibi Saleh Alghamdi Fawaz Alassery Department of Computer Science Guru Arjan Dev Khalsa College Chohla Sahib143408PunjabIndia Al-Nahrain University Al-Nahrain Nano-Renewable Energy Research CenterBaghdad964Iraq Department of Computer Science College of Computer and Information SystemsUmm Al-Qura UniversityMakkah21955Saudi Arabia Department of Information Technology College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Computer Engineering College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

Fruit classification is found to be one of the rising fields in computer and machine *** deep learning-based procedures worked out so far to classify images may have some ill-posed *** performance of the classification scheme depends on the range of captured images,the volume of features,types of characters,choice of features from extracted features,and type of classifiers *** paper aims to propose a novel deep learning approach consisting of Convolution Neural Network(CNN),Recurrent Neural Network(RNN),and Long Short-TermMemory(LSTM)application to classify the fruit *** accuracy depends on the extracted and selected optimal *** learning applications CNN,RNN,and LSTM were collectively involved to classify the *** is used to extract the image *** is used to select the extracted optimal features and LSTM is used to classify the fruits based on extracted and selected images features by CNN and *** study shows the supremacy of proposed over existing Support Vector Machine(SVM),Feed-forwardNeural Network(FFNN),and Adaptive Neuro-Fuzzy Inference System(ANFIS)competitive techniques for fruit images *** accuracy rate of the proposed approach is quite better than the SVM,FFNN,and ANFIS *** has been concluded that the proposed technique outperforms existing schemes.

关键词： Image classification feature extraction type-II fuzzy logic integrator generator deep learning

Antioxidant activity and identification of bioactive compounds from leaves of Anthocephalus cadamba by ultra-performance liquid chromatography/electrospray ionization quadrupole time of flight mass spectrometry

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Asian Pacific Journal of Tropical Medicine 2012年第12期5卷 977-985页

作者： Madhu Chandel Upendra Sharma Neeraj Kumar Bikram singh Satwinderjeet Kaur Department of Botanical and Environmental Sciences Guru Nanak Dev UniversityAmritsar-143005 India Natural Plant Products Division CSIR-Institute of Himalyan Bioresource Technology(Council of scientific and Industrial research)PalampurH.P.-176061 India

Objective:To evaluate the antioxidant potential of different extract/fractions of Anthocephalus cadamba（***）（Roxb.） Miq.（Rubiaceae） and study the tentative identification of their active ***:The extract/fractions were screened for antioxidant activity using various in vitro assays *** assay,ABTS assay,superoxide anion radical scavenging assay, reducing power assay and plasmid DNA nicking *** phenolic content of extract/fractions was determined by colorimetric *** ultra-performance LC-electrospray-quadrupoletime of flight mass spectrometry method was used to analyse the active constituents of extract/ fractions of ***:The ethyl acetate fraction was found to be most active fraction in all the assays as compared to other extract/*** IC50 value of ethyl acetate fraction （ETAC fraction） was 21.24μg/mL,1.12μg/mL,9.68μg/mL and S7.81μg/mL in DPPH assay, ABTS assay,reducing power assay and superoxide scavenging assay *** the extract/ fractions also showed the potential to protect the plasmid DNA（pBR322） against the attack of hydroxyl radicals generated by Fenton’s *** bioactive compounds were identified by UPLC-ESI-QTOF-MS,by comparing the mass andλmax with literature ***:The potential of the extract/fractions to scavenge different free radicals in different systems indicated that they may be useful therapeutic agents for treating radical-related pathologic damage.

关键词： Anthocephalus cadamba Antioxidant activity UPLC-ESI-QTOF-MS

Formulation optimization and characterization of transdermal film of curcumin by response surface methodology

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Chinese Herbal Medicines 2021年第2期13卷 274-285页

作者： Priyanka Kriplani Kumar Guarve Uttam singh Baghel guru Gobind singh College of Pharmacy Yamuna Nagar135001India I.K.Gujral Punjab Technical University Jalandhar 144603India Department of Pharmacy University of KotaKota 324005India

Objective:India is referred as goldmine of herbal drugs but still lack of optimization of herbal drugs,which has kept us on the back *** rationale of the study is to prepare optimized transdermal drug delivery system of curcumin employing response surface methodology to study the collective effect of independent variables like concentration of ethyl cellulose,hydroxyl propyl methyl cellulose and dibutyl phthalate which significantly influenced characteristics like percentage elongation and in vitro drug ***:Twenty formulations containing varying concentrations of polymers and permeation enhancer were prepared using solvent casting ***:The study revealed that the effect of dibutyl phthalate(DBP) concentration was the highest on percentage elongation(P <0.0001),while hydroxy propyl methyl cellulose(HPMC) concentration exhibited pronounced effect on drug release(P <0.0001) through dialysis *** model fitted the best for curcumin release and elongation for all *** to Derringer's desirability prediction tool,the composition of optimized film was found to be 242.14% of HPMC,109.59% of ethyl cellulose(EC),and 1.03% of *** these conditions,the optimized patch exhibited a predicted value of%elongation and in vitro drug release of 94.35% and 80.0306%,respectively,which was comparable to the actual values of percent elongation and in vitro drug release i.e.95.02% and 81.03% *** and thermal studies were also performed which revealed no interaction or complexation between drug and *** ex vivo study performed using rat skin showed that the cumulative drug release from the optimized patch showed flux of(30.68±18) μg/cm~2/***:It can be concluded that in future if proper optimization of herbal formulations is carried out,they can become the first choice for patients as compare to synthetic drugs.

关键词： Curcumin herbal drugs osteoarthritis formulation optimization transdermal film

Rheological,mechanical,thermal,tribological and morphological properties of PLA-PEKK-HAp-CS composite

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Journal of Central South University 2021年第6期28卷 1615-1626页

作者： GURCHETAN singh RANVIJAY Kumar RUPINDER singh MD MUSTAFIZUR Rahman SEERAM Ramakrishna Department of Production Engineering Guru Nanak Dev Engineering CollegeLudhiana 141106India Department of Mechanical Engineering University Center for Research and DevelopmentChandigarh UniversityMohali 140413India Department of Mechanical Engineering National Institute of Technical Teachers Training and ResearchChandigarh 160019India Department of Mechanical Engineering Universiti Malaysia PahangPahang 26600Malaysia Department of Mechanical Engineering National University of Singapore119077Singapore

The present study reports investigations on rheological,mechanical,thermal,tribological and morphological properties of feedstock filaments prepared with polylactic acid-polyether ketone ketone-hydroxyapatite-chitosan(PLA-PEKK-HAp-CS)composite for 3D printing of functional *** study consists of a series of melt processing operations on melt flow index(MFI)setup as per ASTM D-1238 for melt flow certainty followed by fixation of reinforcement composition/proportion as 94%PEKK-4%HAp-2%CS(B)by mass in PLA matrix(A).The blending of reinforcement and preparation of feedstock filament for fused deposition modeling(FDM)set up has been performed on commercial twin screw extruder(TSE).The results of study suggest that feedstock filaments prepared with blend of 95%A-5%B(by mass)at 200℃processing temperature and 100 r/min rotational speed on TSE resulted into better tensile properties(35.9 MPa peak strength and 32.3 MPa break strength)with 6.24%surface porosity,42.67 nm surface roughness(R_(a))and acceptable heat capacity(2.14 J/g).However as regards to tribological behavior,the minimum wear of 316μm was observed for sample with poor tensile *** regards to crash application for scaffolds the maximum toughness of 1.16 MPa was observed for 85%A-15%B(by mass)at 200℃processing temperature and 150 r/min rotational speed on TSE.

关键词： polylactic acid-polyether ketone ketone-hydroxyapatite-chitosan(PLA-PEKK-HAP-CS) twin screw extruder(TSE) differential scanning calorimetry(DSC) melt flow index(MFI) wear test