检索结果-南通市图书馆

Rising incidence,progression and changing patterns of liver disease in Wales 1999-2019

World Journal of Hepatology 2023年第1期15卷 89-106页

作者： Thomas Peter Ignatius Pembroke Gareth John berry puyk Keith Howkins Ruth Clarke Fidan Yousuf Marek Czajkowski Andrew Godkin Jane Salmon Andrew Yeoman Department of Gastroenterology and Hepatology University Hospital of WalesCardiff CF144XNUnited Kingdom Division of Infection and Immunity Cardiff UniversityCardiff CF144XWUnited Kingdom Digital Health and Care Wales NHS WalesCardiff CF119ADUnited Kingdom Gwent Liver Unit Royal Gwent HospitalNewport NP202UBUnited Kingdom Public Health Wales NHS WalesCardiff CF104BZUnited Kingdom

BACKGROUND Liver disease incidence and hence demand on hepatology services is *** To describe trends in incidence and natural history of liver diseases in Wales to inform effective provision of hepatology *** The registry is populated by International Classification of Diseases-10(ICD-10)code diagnoses for residents derived from mortality data and inpatient/day case activity between ***-anonymised linkage of:(1)Causative diagnoses;(2)Cirrhosis;(3)Portal hypertension;(4)Decompensation;and(5)Liver cancer diagnoses enabled tracking liver disease *** The population of Wales in 2019 was 3.1 *** 1999 and 201973054 individuals were diagnosed with a hepatic disorder,including 18633 diagnosed with cirrhosis,10965 with liver decompensation and 2316 with hepatocellular carcinoma(HCC).Over 21 years the incidence of liver diseases increased 3.6 fold,predominantly driven by a 10 fold increase in non-alcoholic fatty liver disease(NAFLD);the leading cause of liver disease from *** incidence of cirrhosis,decompensation,HCC,and allcause mortality ***-related mortality ***-related liver disease(ArLD),autoimmune liver disease and congestive hepatopathy were associated with the highest rates of decompensation and all-cause *** A 10 fold increase in NAFLD incidence is driving a 3.6 fold increase in liver disease in Wales over 21 ***-related morbidity and mortality rose more slowly reflecting the lower progression rate in *** of ArLD remained stable but was associated with the highest rates of liver-related and all-cause mortality.

关键词： Epidemiology Cirrhosis Liver failure Non-alcoholic fatty liver disease hepatitis Hepatocellular carcinoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The singularities of light:intensity,phase,polarisation

引用

Light(Science & Applications) 2023年第10期12卷 2023-2026页

作者： Michael V.berry H H Wills Physics Laboratory BristolBS81TLUK

In modern optics,light can be described at different levels:as rays,as scalar waves,as vector fields,and as quantum *** the first three levels,there are singularities—characteristic features,useful in interpreting phenomena at that *** geometrical optics,the singularities are ray caustics;in scalar wave optics,they are phase singularities(=wave dislocations=wave vortices=nodal manifolds);in vector waves,they are singularities where the polarisation of light is purely linear or purely *** singularities at each level are dissolved at the next *** singularities occur in all waves,not just light.

关键词： optics purely polar

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatic, pancreatic and renal manifestations of a ciliopathy

引用

Hepatobiliary & Pancreatic Diseases International 2021年第4期20卷 394-395页

作者： Sreelakshmi Kotha Philip berry Department of Gastroenterology Guy’s and St Thomas’Foundation TrustLondonUK

Hepatorenal fibrocystic diseases are inherited disorders,characterized by developmental abnormalities and fibrocystic degeneration of the portobiliary system and kidneys^([1]).They are part of a larger group of disorders referred to as"ciliopathies"which affect 1 in 1000 *** kidney disease is the most common kidney manifestation,while others include nephronophthisis,glomerulocystic disease and cystic *** manifesta-tions include Caroli’s disease,congenital hepatic fibrosis and poly-cystic liver disease.

关键词： Hepatic kidney degeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hepatitis A vaccine associated with autoimmune hepatitis

引用

World Journal of Gastroenterology 2007年第15期13卷 2238-2239页

作者： PA berry G Smith-Laing Medway Maritime Hospital Windmill Road GillinghamKentUnited Kingdom

To describe a case of probable relapsing autoimmune hepatitis associated with vaccination against hepatitis A virus （HAV）. A case report and review of literature were written concerning autoimmune hepatitis in association with hepatitis A and other hepatotropic viruses. Soon a^er the administration of formalin-inactivated hepatitis A vaccine, a man who had recently recovered from an uncharacterized but self-limiting hepatitic illness, experienced a severe deterioration （AST 1687 U/L, INR 1.4）. Anti-nuclear antibodies were detectable, and liver biopsy was compatible with autoimmune hepatitis. The observation supports the role of HAV as a trigger of autoimmune hepatitis. Studies in helper T-cell activity and antibody expression against hepatic proteins in the context of hepatitis A infection are summarized, and the concept of molecular mimicry with regard to other forms of viral hepatitis and autoimmunity is briefly explored.

关键词： Hepatitis A virus Vaccine Autoimmune hepatitis Helper T-cell Molecular mimicry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuances of oblique lumbar interbody fusion at L5-S1:Three case reports

引用

World Journal of Orthopedics 2021年第6期12卷 445-455页

作者： Chirag A berry Department of Orthopaedics Cincinnati VA Medical CenterCincinnatiOH 45220United States

BACKGROUND Oblique lumbar interbody fusion is a mini-open retroperitoneal approach that uses a wide corridor between the left psoas muscle and the aorta above *** approach avoids the limitations of lateral lumbar interbody fusion,is considered less invasive than anterior lumbar interbody fusion,and is similarly effective for indirect decompression and improving lordosis while maintaining a low complication *** L5-S1,when required,adds to these advantages,as this allows single-position ***,variations in vascular anatomy can affect the ease of access to the L5-S1 *** nuances of three different oblique anterolateral techniques to access L5-S1 for interbody fusion,namely,left-sided intra-bifurcation,left-sided pre-psoas,and right-sided pre-psoas approaches,are illustrated using three representative case *** SUMMARY Cases of three patients who underwent multilevel oblique lumbar interbody fusion including L5-S1,using one of the three different techniques,are *** patients presented with symptomatic degenerative lumbar pathology and failed conservative management prior to *** anatomical considerations that affected the decisions to utilize each approach are *** pros and cons of each approach are also discussed.A parasagittal facet line objectively assesses the relationship between the left common iliac vein and the L5-S1 disc and assists in choosing the approach to *** Oblique retroperitoneal access to L5-S1 in the lateral decubitus position is possible through three different *** choice of approach to L5-S1 may be individualized based on a patient’s vascular anatomy using preoperative *** most surgeons will rely on their experience and comfort level in choosing the approach,this article elucidates the nuances of each technique.

关键词： Oblique lumbar interbody fusion Prepsoas approach Anterior to psoas Common iliac vein Iliolumbar vein Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Glucose measurement via Raman spectroscopy of graphene:Principles and operation

引用

Nano Research 2022年第10期15卷 8697-8704页

作者： Alireza Ahmadianyazdi Ngoc Hoang Lan Nguyen Jie Xu Vikas berry Department of Mechanical and Industrial Engineering University of Illinois at ChicagoChicagoIllinois 60607USA Department of Chemical Engineering University of Illinois at ChicagoChicagoIllinois 60607USA

The sensitivity of graphene’s Raman characteristics to external perturbations can be exploited for sensing *** apply this principle,Raman spectroscopy of graphene in contact with a chemical/biological analyte is recorded to unravel a correlation between analyte’s physical/chemical/biological properties and electronic properties(Fermi energy and dopants level)of *** an example,we demonstrate the principle and operation of glucose measurement using graphene’s Raman spectroscopy,utilizing both affinity and enzymatic detection *** the affinity detection,we monitor Raman spectrum of graphene in contact with a glucose containing sample to quantify the attachment of glucose onto 1-pyrene boronic acid(PBA)functionalized *** is revealed that glucose covalent bond to PBA induces n-type doping in graphene and increases its Fermi level following the Hill–Langmuir *** the enzymatic detection,we show that graphene’s Fermi energy shifts due to the biocatalytic oxidation of glucose by immobilized glucose oxidase(GOx)*** a result,graphene becomes p-doped with increasing glucose *** attribute this sensitivity to a re-distribution of ionic charges within the electric double layer(EDL)of graphene upon introducing the glucose *** model explains both our affinity and enzymatic glucose detection *** glucose detection,our graphene Raman spectroscopy-based sensor(GRS)may extend its applications to a broader range of remote and non-invasive detection without the need to employ electronics such as field-effect transistors.

关键词： graphene Raman spectroscopy glucose affinity detection glucose oxidase

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Predicting the Thermal Behavior in Functional Textile Fibers Having Embedded Electronics

引用

Advanced Fiber Materials 2022年第6期4卷 1609-1619页

作者： Shaun berry Shawn Redmond Tairan Wang Mordechai Rothschild MIT Lincoln Laboratory 244 Wood StreetLexingtonMA 02421USA

In this paper,both steady-state and transient thermal simulations were performed on functional fibers having an embedded electronic chip acting as a heat *** were conducted for a range of different fiber materials and arbitrary fiber cross-sectional *** show that under steady-state heating conditions,the thermal response for any arbitrary fiber shape and fiber material system was convection dominated regardless of the effective thermal conductivity of the fiber,and that the corresponding temperature rise within the fiber can be predicted analytically allowing for the maximum temperature to be estimated for any known heat load and fiber *** the case of transient heating,we show that for pulsed power operation of the embedded electronic device,the maximum temperature reached in the fiber is always greater than the maximum temperature of the equivalent steady-state average ***,high peak powers can be safely achieved if the power-on pulse time and duty cycle are selected to limit the maximum temperature reached in the *** on the results from the transient simulations,a set of criteria was developed to determine whether the operating conditions would be:(1)allowable for the fiber system,thus requiring no transient simulations,(2)requiring a transient simulation to verify that the maximum temperature is acceptable,and(3)the operating conditions are too severe and device operation at these conditions are not practical.

关键词： Functional fibers Smart fibers Thermal modeling Fabrics MOEMS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Decorin treatment of spinal cord injury

引用

Neural Regeneration Research 2014年第18期9卷 1653-1656页

作者： Maryam Esmaeili Martin berry Ann Logan Zubair Ahmed Neurotrauma Research Group Neurobiology SectionSchool of Clinical and Experimental MedicineUniversity of Birmingham

The scarring response after a penetrant central nervous system injury results from the interaction between invading leptominingeal/pericyte-derived fibroblasts and endogenous reactive astrocytes about the wound margin. Extracellular matrix and scar-derived axon growth inhibitory mole- cules fill the lesion site providing both a physical and chemical barrier to regenerating axons. Dec orin, a small leucine-rich chondroitin-dermatan sulphate proteoglycan expressed by neurons and astrocytes in the central nervous system, is both anti-fibrotic and anti-inflammatory and attenu- ates the formation and partial dissolution of established and chronic scars. Here, we discuss the potential of using Decorin to antagonise scarring in the central nervous system.

关键词： spinal cord injury Decorin transforming growth factor-beta scarring chondroiti^sulphate proteoglycan matrix metalloproteases

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unrecognized pylephlebitis causing life-threatening septic shock: A case report

引用

World Journal of Gastroenterology 2005年第4期11卷 614-615页

作者： Matthew Wireko Philip A berry John Brennan Rakesh Aga Medway Maritime Hospital Windmill Road Gillingham KentME4 6TWUnited Kingdom

A man who developed profound septic shock was treated for Escherichia colisepsis of unknown origin. Following stabilisation, a diagnosis of pylephlebitis (infection and thrombosis in the portal vein) was made at computed tomography. A review of the condition, its primary causes,typical features, investigation and management was presented.

关键词： Pylephlebitis Septic shock

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Investigation of the anisotropic confinement-dependent brittleness of a Utah coal

引用

International Journal of Coal Science & Technology 2021年第2期8卷 274-290页

作者： Bo-Hyun Kim Gabriel Walton Mark KLarson Steve berry CDC/NIOSH 315 E.Montgomery Ave.SpokaneWAUSA Department of Geology and Geological Engineering Colorado School of MinesGoldenCOUSA Department of Geological Engineering Montana TechButteMTUSA

Changes of failure mechanism with increasing confinement,from extensional to shear-dominated failure,are widely observed in the rupture of intact specimens at the laboratory scale and in rock *** an analysis published in 2018,both unconfined and triaxial compressive tests were conducted to investigate the strength characteristics of 84 specimens of a Utah coal,including the spalling limits,the ratio of apparent unconfined compressive strength to unconfined compressive strength(UCS),the damage characteristics,and the post-yield *** mechanical characteristics were found to be strongly anisotropic as a function of the orientation of the cleats relative to the loading direction,defined as the included angle.A total of four different included angles were used in the work performed in *** authors found that the degree of anisotropic strength differed according to the included ***,the transition from extensional to shear failure at the given confinements was not clearly *** this study,a total of 20 specimens were additionally prepared from the same coal sample used in the previous study and then tested under both unconfined and triaxial compressive *** the authors already knew the most contrasting cases of the included angles from the previous work using the four included angles,they chose only two of the included angles(0°and 30°)for this *** the triaxial compressive tests,a greater confining stress than the mean UCS was applied to the specimens in an attempt to identify the brittle-ductile transition of the *** new results have been compiled with the previous results in order to re-evaluate the confinement-dependency of the coal ***,the different confining stresses are used as analogs for different width-to-height(W/H)conditions of pillar *** the W/H ratios of the specimens were not directly considered during testing,the equivalent W/H ratios of a pillar as a function of

关键词： Utah coal Spalling limit AUCS/UCS ratio Damage characteristic Post-yield dilatancy Anisotropic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：