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Global paleobiogeography of Albian—Cenomanian(mid-Cretaceous)marine ostracods

Journal of Palaeogeography 2024年第2期13卷 212-236页

作者： bernardo vázquez-garcía Jorge villegas-Martín Gerson Fauth Leonardo Borghi Aristóteles De Moraes Rios Netto Post-Graduate Program in Geology Unisinos UniversitySao LeopoldoRSBrazil Technological Institute of Paleoceanography and Climate Change-Itt Oceaneon Unisinos UniversitySao LeopoldoRSBrazil Laboratory of Sedimentary Geology(Lagesed) Department of GeologyInstitute of GeosciencesUFRJ-Federal Universityof Riode JaneiroBrazil Labmicro Department of GeologyInstitute of GeosciencesUFRJ-Federal University of Rio de JaneiroBrazil

Despite their potential for providing important information for paleobiogeography,studies using ostracod assemblages compiled from global datasets have been scarce so *** this study,the paleogeographic implications of the relationship between different ostracod assemblages are analyzed and discussed for the Albian and *** compiled an ostracod dataset at the genus level,with 168 genera for the Albian and 174 for the Cenomanian,to which different multivariate statistical methods of grouping were *** affinity between different ostracod assemblages from different regions allowed for the delineation of 30 operational geographic units(OGUs)for the Albian,and 32 OGUs for the Cenomanian,grouped in three paleobiogeographic units(PBUs;Megatethys,Persia,and Austral)and one sub-unit(PBSU;Maghreb associated to the Megatethys).The Maghreb PBSU showed minor changes between the Albian and *** relationship among the OGUs grouped in each PBU is related to different factors,such as eustatic sea level events,similar climatic zones,and marine current circulation patterns.A relationship was observed between the Gabon and Nigeria OGUs with the Persia PBU,which suggests a direct east—west connection between them during the *** affinity observed in the Austral PBU between the South American,South African,and Australian regions during the Albian can be explained by their relative geographic isolation due to the Walvis Ridge *** eventual flooding of this barrier led to the relationship observed between the SE Brazilian and Bolivian regions with the Austral ***,the data also suggested that the separation of the Indian subcontinent from the Austral PBU took place during the Cenomanian.

关键词： Operational geographic units Paleobiogeographic units Albian Cenomanian Marine ostracods

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Screen-printed graphite electrode on polyvinyl chloride and parchment strips integrated with genetic programming for in situ nitrate sensing of aquaponic pond water

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Information Processing in Agriculture 2024年第2期11卷 187-201页

作者： Ronnie ConcepcionⅡ bernardo Duarte Maria Gemel Palconit Jonah Jahara BaunArgel Bandala Ryan Rhay vicerra Elmer Dadios Department of Manufacturing Engineering and Management De La Salle UniversityManila 1004 Philippines MARE-Marine and Environmental Sciences Centre.&ARNET-Aquatic Research Infrastructure Network Associated Laboratory Faculdade de Ciencias da Universidade de LisboaCampo Grande1749-016 LisboaPortugal Departamento de Biologia vegetal da Faculdade de Ciencias da Universidade de Lisboa Campo Grande 1749-016 LisboaPortugal Department of Electronics and Computer Engineering De La Salle UniversityManila 1004 Philppines

Nitrate is the primary water-soluble macronutrient essential for plant growth that is converted from excess fish feeds,fish effluents,and degrading biomaterials on the aquaponic pond floor,and when aquacultural malpractices occur,large amounts of it retain in the water system causing increase rate in eutrophication and toxifies fish and aquaculture *** nitrate sensor prototypes still require performing the additional steps of water sample deionization and dilution and were constructed with expensive *** response to the challenge of sensor enhancement and aquaponic water quality monitoring,this study developed sensitive,repeatable,and reproducible screen-printed graphite electrodes on polyvinyl chloride and parchment paper substrates with silver as electrode material and 60:40 graphite powder:nail polish formulated conductive ink for electrical traces,integrated with 9-gene genetic expression model as a function of peak anodic current and electrochemical test time for nitrate concentration prediction that is embedded into low-power Arduino ESP32 for in situ nitrate sensing in aquaponic pond *** SPE electrical traces were designed on the two types of *** electron microscopy with energy dispersive X-ray confirmed the electrode surface *** cyclic voltammetry using 10 to 100 mg/L KNO3 and water from three-depth regions of the actual pond established the electrochemical test time(10.5 s)and electrode potential(0.135 v)protocol necessary to produce peak current that corresponds to the strength of nitrate ions during *** findings from in situ testing revealed that the proposed sensors have strong linear predictions(R2=0.968 MSE=1.659 for nSPEv and R2=0.966 MSE=4.697 for nSPEp)in the range of 10 to 100 mg/L and best detection limit of 3.15μg/L,which are comparable to other sensors of more complex *** developed three-electrode electrochemical nitrate sensor confirms that it is reliable for bot

关键词： Aquaponic water quality Electrochemical technology Genetic programming Graphite electrode Nitrate sensor Precision agriculture Printed electronics Scanning electron microscopy Screen-printed electrode voltammetry

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Gate-controlled supercurrent effect in dry-etched Dayem bridges of non-centrosymmetric niobium rhenium

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Nano Research 2024年第7期17卷 6575-6581页

作者： Jennifer Koch Carla Cirillo Sebastiano Battisti Leon Ruf Zahra Makhdoumi Kakhaki Alessandro Paghi Armen Gulian Serafim Teknowijoyo Giorgio De Simoni Francesco Giazotto Carmine Attanasio Elke Scheer Angelo Di bernardo Department of Physics University of KonstanzUniversitätsstraße 1078464 KonstanzGermany CNR-Spin c/o Universitàdegli Studi di Salernovia Giovanni Paolo II 13284084 Fisciano(SA)Italy NEST Istituto Nanoscienze-CNR and Scuola Normale SuperiorePiazza San Silvestro 1256127 PisaItaly Dipartimento di Fisica“E.R.Caianiello” Universitàdegli Studi di SalernoVia Giovanni Paolo II 13284084 Fisciano(SA)Italy Advanced Physics Laboratory Institute for Quantum StudiesChapman UniversityBurtonsvilleMD 20866USA

The application of a gate voltage to control the superconducting current flowing through a nanoscale superconducting constriction,named as gate-controlled supercurrent(GCS),has raised great interest for fundamental and technological *** gain a deeper understanding of this effect and develop superconducting technologies based on it,the material and physical parameters crucial for the GCS effect must be ***-down fabrication protocols should also be optimized to increase device scalability,although studies suggest that top-down fabricated devices are more resilient to show a ***,we investigate gated superconducting nanobridges made with a top-down fabrication process from thin films of the noncentrosymmetric superconductor niobium rhenium with varying ratios of the constituents(NbRe).Unlike other devices previously reported and made with a top-down approach,our NbRe devices systematically exhibit a GCS effect when they were fabricated from NbRe thin films with small grain size and etched in specific *** observations pave the way for the realization of top-down-made GCS devices with high *** results also imply that physical parameters like structural disorder and surface physical properties of the nanobridges,which can be in turn modified by the fabrication process,are crucial for a GCS observation,providing therefore also important insights into the physics underlying the GCS effect.

关键词： superconductivity non-centrosymmetric superconductors superconducting devices gated devices gate-controlled supercurrent top-down fabrication

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Possible Uses for Silymarin in Human Health: Systematic Review

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American Journal of Plant Sciences 2024年第2期15卷 95-109页

作者： Gisele Mara Silva Gonçalves Andre bernardo de Camargo Eisingher Postgraduate Program in Health Sciences Pontifical Catholic University of Campinas (PUC-Campinas) Campinas Brazil

Silymarin, from the fruit of Silybum marianum, is known for its hepatoprotective action. The aim of this study was to review the mechanisms of action of the silymarin phytocomplex to expand the possibilities for its application in human health. The search for published articles was carried out on the CAPES Journals Portal platform, which covers worldwide scientific databases. Publications from 2010 to 2022 were included. Of the 311 articles retrieved, 21 were included. The articles discuss the diversity of silymarin’s applications and the possibility of optimizing its bioavailability using drug delivery systems. Silymarin shows promise in numerous diseases, such as liver, kidney, cardiovascular, respiratory and others. Its antiviral action has been demonstrated in studies and silymarin has the potential to be used as a complementary therapy in the treatment of many diseases, with the expectation that, in the future, it will be used in therapeutic protocols for exclusive use.

关键词： Silymarin Flavonoids Phytotherapeutic Drugs

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Effect of initial microstructure on austenite formation kinetics in high-strength experimental microalloyed steels

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International Journal of Minerals,Metallurgy and Materials 2015年第12期22卷 1304-1312页

作者： Edgar López-Martínez Octavio vázquez-Gómez Héctor Javier vergara-Hernández bernardo Campillo Faculty of Chemistry Metallurgical Engineering Department Autonomous National University of Mexico National Council for Science and Technology Metallurgy Science Postgraduate Programme Morelia Institute of Technology Institute of Physical Sciences Autonomous National University of Mexico

Austenite formation kinetics in two high-strength experimental microalloyed steels with different initial microstructures comprising bainite-martensite and ferrite-martensite/austenite microconstituents was studied during continuous heating by dilatometric analysis. Austenite formation occurred in two steps：（1） carbide dissolution and precipitation and （2） transformation of residual ferrite to austenite. Dilatometric analysis was used to determine the critical temperatures of austenite formation and continuous heating transformation diagrams for heating rates ranging from 0.03°C.s^-1 to 0.67°C.s^-1. The austenite volume fraction was fitted using the Johnson-Mehl-Avrami-Kolmogorov equation to determine the kinetic parameters k and n as functions of the heating rate. Both n and k parameters increased with increasing heat- ing rate, which suggests an increase in the nucleation and growth rates of austenite. The activation energy of austenite formation was determined by the Kissinger method. Two activation energies were associated with each of the two austenite formation steps. In the first step, the austenite growth rate was controlled by carbon diffusion from carbide dissolution and precipitation; in the second step, it was controlled by the dissolution of residual ferrite to austenite.

关键词： non-isothermal kinetics microalloyed steel austenite heating dilatometry

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Biomedical overview of *** molecular modeling,synthesis mechanism,and supramolecular properties regarding melanoma therapy

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BIOCELL 2022年第6期46卷 1391-1415页

作者： JUAN CARLOS STOCKERT ALFONSO BLÁzquez-CASTRO Facultad de Medicina Instituto de Oncología“Angel H.Roffo”Universidad de Buenos AiresBuenos AiresC1417DTBArgentina Centro Integrativo de Biología y Química Aplicada(CIBQA) Universidad Bernardo O’HigginsSantiago8370854Chile Departamento de Biología Facultad de CienciasUniversidad Autónoma de MadridMadrid28049Spain

Melanins represent one of the most ancient and important group of natural macromolecular *** have multiple biological roles in almost all organisms across the Phyla,examples being photoprotection,anti-oxidative action,radical scavenger activity,and heavy metal *** the biomedical point of view,melanocytes are involved in the origin of melanoma tumors,and the main therapeutic advances for their treatment have been revised in Part 1 of this *** chemical structure of eumelanin is a biological concern of great importance,and therefore,exploring theoretical molecular models and synthesis mechanisms will be here described,as well as molecular orbital features and supramolecular organization,which are responsible for the key properties that make these biological pigments so important,and so ***,this updated overview is devoted to describe present structural models and physico-chemical characteristics of eumelanin,in order to explain and utilize melanin properties on which new photothermal and ultrasonic protocols for melanoma treatment can be devised and applied.

关键词： Eumelanin Melanin models Melanin synthesis Molecular orbitals Supramolecular structure

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Unilateral blurred vision in pediatric patient associated with cavum velum interpositum cyst

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International Journal of Ophthalmology(English edition) 2023年第7期16卷 1164-1166页

作者： Margarita Zamorano Esperanza garcía-Romo Román Blanco-velasco Belén Fernández Francisco J.Monescillo bernardo Fernández de Arévalo Department of Ophthalmology University Hospital GuadalajaraGuadalajara 19002Spain

Dear Editor,We present for the first time,a case of a paediatric patient with symptoms of intermittent blurred vision as first symptom of a cavum of the velum interpositum(CvI).Intracranial anterior midline cysts can ... 详细信息

关键词： patient pediatric vel

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Superconvergent Interpolatory HDG Methods for Reaction Difusion Equations II:HHO‑Inspired Methods

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Communications on Applied Mathematics and Computation 2022年第2期4卷 477-499页

作者： Gang Chen bernardo Cockburn John R.Singler Yangwen Zhang College of Mathematics Sichuan UniversityChengdu 610065SichuanChina School of Mathematics University of MinnesotaMinneapolisMNUSA Department of Mathematics and Statistics Missouri University of Science and TechnologyRollaMOUSA Department of Mathematical Science University of DelawareNewarkDEUSA

In Chen et al.(***.81(3):2188–2212,2019),we considered a superconvergent hybridizable discontinuous Galerkin(HDG)method,defned on simplicial meshes,for scalar reaction-difusion equations and showed how to defne an interpolatory version which maintained its convergence *** interpolatory approach uses a locally postprocessed approximate solution to evaluate the nonlinear term,and assembles all HDG matrices once before the time integration leading to a reduction in computational *** resulting method displays a superconvergent rate for the solution for polynomial degree k≥*** this work,we take advantage of the link found between the HDG and the hybrid high-order(HHO)methods,in Cockburn et al.(ESAIM ***.50(3):635–650,2016)and extend this idea to the new,HHO-inspired HDG methods,defned on meshes made of general polyhedral elements,uncovered *** meshes made of shape-regular polyhedral elements afne-equivalent to a fnite number of reference elements,we prove that the resulting interpolatory HDG methods converge at the same rate as for the linear elliptic ***,we obtain superconvergent methods for k≥0 by some *** thus maintain the superconvergence properties of the original *** present numerical results to illustrate the convergence theory.

关键词： Hybrid high-order methods Hybridizable discontinuous Galerkin methods Interpolatory method Superconvergence

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Clinical significance of"anti-HBc alone"in human immunodeficiency virus-positive patients

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World Journal of Gastroenterology 2009年第10期15卷 1237-1241页

作者： M~aTeresa Pérez-Rodríguez bernardo Sopea Manuel Crespo Alberto Rivera Teresa González del Blanco Antonio Ocampo César Martínez-vázquez Infectious Diseases Unit Internal Medicine DepartmentXeral-Cíes University Hospital36204 VigoSpain Faculty of Medicine University of Santiago de Compostela15705 Santiago de CompostelaA CoruaSpain Infectious Diseases Department Vall d' Hebron Hospital08035 BarcelonaSpain Microbiology Department Xeral-Cíes University Hospital36204 VigoSpain

AIM:To determine the prevalence and clinical relevance of isolated antibodies to hepatitis B core antigen as the only marker of infection("anti-HBc alone")among human immunodeficiency virus(HIv) type-1 infected *** hepatitis B infection frequency was also evaluated. METHODS:Three hundred and forty eight histories from 2388 HIv-positive patients were randomly *** with serological markers of hepatitis B virus(HBv)infection were classified into three groups:past hepatitis,"anti-HBc alone"and chronic *** of DNA from HBv,and RNA and genotype from hepatitis C virus(HCv)were performed on"anti-HBc alone"patients. RESULTS:One hundred and eighty seven(53.7%) HIv-positive patients had markers of HBv infection: 118 past infection(63.1%),14 chronic hepatitis (7.5%)and 55"anti-HBc alone"(29.4%).Younger age[2.3-fold higher per every 10 years younger;95% confidence intervals(CI)1.33-4.00]and antibodies to HCv infection[odds ratio(OR)2.87;95%CI 1.10-7.48]were factors independently associated with the"anti-HBc alone"*** differences in liver disease frequency were detected between both groups. Serum levels of anti-HBs were not associated with HCv infection(nor viral replication or HCv genotype),or with HIv replication or CD4 ***"anti-HBc alone" patient tested positive for HBv DNA. CONCLUSION:"Anti-HBc alone"prevalence in HIvpositive patients was similar to previously reported data and was associated with a younger age and with antibodies to HCv *** clinical practice,HBv DNA determination should be performed only in those patients with clinical or analytical signs of liver injury.

关键词：人类免疫缺陷病毒阳性患者临床意义 HBc 丙型肝炎病毒感染乙型肝炎病毒感染 HBv感染标志物丙型肝炎病毒基因型

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Three-dimensional analysis of the gap space under forearm casts

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Chinese Journal of Traumatology 2022年第2期25卷 77-82页

作者： Roman Wirtz Silvia Pianigiani bernardo Innocenti Frédéric Schuind Department of Orthopaedics and Traumatology UniversitéLibre de BruxellesCampus Hospitalo-Facultaire Erasme1070BruxellesBelgium BEAMS Department UniversitéLibre de BruxellesÉcole Polytechnique de Bruxelles1050BruxellesBelgium

Purpose:Secondary displacement represents a frequent complication of conservative treatment of fractures,particularly of the distal *** gap space between skin and cast may lead to a certain degree movements and this increased mobility might favor *** aim of this study was to develop a new 3D method,to measure the gap space in all 3 geometrical planes,and to validate this new technique in a clinical setting of distal radius ***:This study applies 3D imaging to measure the space between plaster and skin as a potential factor of secondary displacement and therefore the failure of conservative *** developed and validated a new methodology to analyze and compare different forearm casts made of plaster of Paris and *** unpaired t-test was performed to document differences between the investigated parameters between plaster of Paris and fiberglass *** significance level was set at pverage 4 mm,being slightly inferior on the radial *** the two different casting materials,plaster of Paris and fiberglass,we found a significantly larger variance of space under casts made of the first material(p=0.39).A roughness analysis showed also a markedly significantly higher irregularity of the undersurface of plaster of Paris as compared with ***:This study allows for a better understanding of the nature of the"gap space"between cast and skin and will contribute to develop and improve new immobilization techniques and materials.

关键词： Forearm Wrist casts Radius fractures Conservative treatment Gap space

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