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Journal of Environmental Sciences 2019年第5期31卷 311-320页

作者： Quang Viet Ly Mi-hee lee Jin Hur Department of Environment & Energy Sejong University

Tracking the variation of the algogenic organic matter(AOM) released during the proliferation of green algae and subsequent treatment processes is crucial for constructing and optimizing control strategies. In this study, the potential of the spectroscopic tool was fully explored as a surrogate of AOM upon the cultivation of green algae and subsequent coagulation/flocculation(C/F) treatment processes using ZrCl_4 and Al_2(SO_4)_3. Fluorescence excitation emission matrix coupled with parallel factor analysis(EEM-PARAFAC) identified the presence of three independent fluorescent components in AOM, including protein-like(C1), fulvic-like(C2) and humic-like components(C3). Size exclusion chromatography(SEC) revealed that C1 in AOM was composed of large-sized proteins and aromatic amino acids. The individual components exhibited their unique characteristics with respect to the dynamic changes. C1 showed the highest correlation with AOM concentrations(R^2= 0.843) upon the C/F processes. C1 could also be suggested as an optical predictor for the formation of trihalomethanes upon the C/F processes. This study sheds a light for the potential application of the protein-like component(C1) as a practical surrogate to track the evolution of AOM in water treatment or wastewater reclamation systems involving Chlorella vulgaris green algae.

关键词： EEM-PARAFAC Enhanced coagulation Size exclusion chromatography Algal dissolved organic matter Trihalomethanes

^(27)Al MAS-NMR study of inorganic polymer formation at ambient temperature

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Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 182-187页

作者： Sang-Wook AHN hee-Soo lee Wan-hee YANG Jung-Woo lee Young-Keun JEONG National Core Research Center for Hybrid Materials Solution Pusan National University School of Material Science and Engineering Pusan National University INTChem Co. Ltd.

Inorganic polymers are a novel class of materials formed by the polymerization of silicon, aluminium and oxygen species to form an amorphous three-dimensional framework structure. The basis of this process is the alkaline solutions to induce a certain amount of Si and AI atoms to dissolve from a feedstock such as aluminosilicate. A study of 27A1 MAS-NMR was carried out in an attempt to understand the reaction mechanism of the inorganic polymerization at ambient temperature. Scanning electron microscopy （SEM） and X-ray diflYactometry （XRD） were also employed to establish the composition and microstructure of the inorganic polymerization. Specimens were prepared with different A1/Si mole ratios from the starting materials. The higher the AI content, the more sufficient the AI atoms that can combine with SiO4, and the longer the reaction time, the more the bonded Si--O--A1--O polymer structure, and then the higher the A1 content, the fewer the octahedral A1 with a uniform Si--O--A1--O structure in four directions, because four AI atoms are combined with SiO4, resulting in a uniform Si--O--AI--O structure in four directions. The results show that they have an amorphous microstructure.

关键词： inorganic polymer amorphous tetrahedral

Parameterization and Application of Storm Surge/Tide Modeling Using a Genetic Algorithm for Typhoon Periods

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Advances in Atmospheric Sciences 2011年第5期28卷 1067-1076页

作者： Sung Hyup YOU Yong hee lee Woo Jeong lee Marine Meteorology Division Observation Infrastructure Bureau/KMA Korea Forecast Research Laboratory National Institute of Meteorological Research/KMA Korea Global Environment System Research Laboratory National Institute of Meteorological Research/KMA Korea

A genetic algorithm was used to optimize the parameters of the two-dimensional Storm Surge/Tide Operational Model （STORM） to improve sea level *** genetic algorithm was applied to nine typhoons that affected the Korean Peninsula during *** following model parameters were used：the bottom drag coefficient,the background horizontal diffusivity,Smagorinski＇s horizontal viscosity,and the sea level pressure ***,the simulation results using the optimized,mean,and median parameter values improved sea level *** four estimated parameters improved the sea level prediction by 76% and 54% in the bias and root mean square error for Typhoon Kalmaegi （0807） in 2008,***-month simulations of February and August 2008 were also improved using the estimated *** study demonstrates that parameter optimization on STORM can improve sea level prediction.

关键词： genetic algorithm STORM sea level typhoon

Stimulation of melanogenesis by scoparone in B16 melanoma cells

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Acta Pharmacologica Sinica 2006年第11期27卷 1467-1473页

作者： Jeong-yeh YANG Jeung-hyunKOO Young-gilSONG Kang-beom KWON Ju-hyung lee hee-sook SOHN Byung-hyun PARK Eun-chung Jhee Jin-woo PARK Department of Biochemistry Dental SchoolChonbuk National UniversityJeonju 561-756Korea Department of Biochemistry Medical School Chonbuk National UniversityJeonju 561-756Korea Department of Physiology School of Oriental MedicineWon-Kwang UniversityIksan 570-749Korea Department of Preventive Medicine Medical School Department of Food Science and Human Nutrition College of Home EconomyChonbuk National UniversityJeonju 561-756Korea Department of Biochemistry Medical SchoolChonbuk National UniversityJeonju 561-756Korea Institute for Healthcare Technology DevelopmentChonbuk National UniversityJeonju 561-756Korea Department of Biochemistry Medical SchoolChonbuk National UniversityJeonju 561-756Korea Institute for Healthcare Technology Development Chonbuk National UniversityJeonju 561-756Korea

Aim:The effect of coumarin derivatives on melanogenesis was investigated inB16 murine melanoma ***:Melanin content and tyrosinase activitywere analyzed *** expression of tyrosinase,tyrosinase-related protein-1(TRP-1)and tyrosinase-related protein-2(TRP-2)were measuredeither by reverse transcription-polymerase chain reaction(RT-PCR)or ***:Among the coumarin derivatives studied,scoparone(6,7-dimethoxycoumarin)was the most potent;the 6-or 7-methoxy group was found tobe essential for the stimulation of *** melanin content was greatlyincreased by scoparone in a dose-dependent manner;there was no cytotoxicity atthe effective *** increased enzyme activity as well asprotein and mRNA expression of *** addition,mRNA of TRP-1 andTRP-2 were also increased after treatment with scoparone.H-89,an inhibitor ofprotein kinase A(PKA),completely inhibited the scoparone-induced increase ofmelanogenesis and the tyrosinase ***:These results suggestthat scoparone-induced stimulation of melanogenesis is likely to occur at thetranscriptional level of melanogenesis-related enzymes through PKA signaling.

关键词： melanogenesis scoparone (6,7-dimethoxy-coumarin) tyrosinase tyrosinase-related proteins protein kinase A

Antibiotic use in children with Kawasaki disease

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World Journal of Pediatrics 2018年第6期14卷 621-622页

作者： Seung beom Han Soo-Young lee Department of Pediatrics St.Paul’s HospitalCollege of MedicineThe Catholic University ofK orea180 Wangsan-roDongdaemun-guSeoul 02559RepublicofK orea

As the diagnostic criteria for Kawasaki disease (KD) consist of the clinical features that are shared by other childhood febrile illnesses [1, 2], KD is sometimes confused with a bacterial infection, leading to clinical situations in which children with the disease receive antibiotics (3–5)Here, we report the extent of antibiotic use in children with KD and the clinical parameters confusing KD with a bacterial infection.

关键词： Antibiotic children Kawasaki disease

Two macrophages, osteoclasts and microglia: from development to pleiotropy

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Bone Research 2021年第2期9卷 143-152页

作者： Ji-Won lee In-hee lee Tadahiro Iimura Sek Won Kong Department of Nephrology Transplant Research ProgramBoston Children’s HospitalBostonMA 02115USA Department of Pharmacology Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Computational Health Informatics Program Boston Children’s HospitalBostonMA 02115USA Department of Pediatrics Harvard Medical SchoolBostonMA 02115USA

Tissue-resident macrophages are highly specialized to their tissue-specific microenvironments,activated by various inflammatory signals and modulated by genetic and environmental *** and microglia are distinct tissue-resident cells of the macrophage lineage in bone and brain that are responsible for pathological changes in osteoporosis and Alzheimer’s disease(AD),*** is more frequently observed in individuals with AD compared to the prevalence in general *** of AD is often delayed until underlying pathophysiological changes progress and cause irreversible damages in structure and function of *** such earlier diagnosis and intervention of individuals at higher risk would be indispensable to modify clinical *** is the phenomenon that a genetic variant affects multiple traits and the genetic correlation between two traits could suggest a shared molecular *** this review,we discuss that the Pyk2-mediated actin polymerization pathway in osteoclasts and microglia in bone and brain,respectively,is the horizontal pleiotropic mediator of shared risk factors for osteoporosis and AD.

关键词： diagnosis osteoporosis osteoclast

Cutaneous ciliated cyst on the anterior neck in young women: A case report

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World Journal of Clinical Cases 2020年第19期8卷 4481-4487页

作者： Yon hee Kim Jihyoun lee Department of Pathology Soonchunhyang University Seoul HospitalSeoul 04401South Korea Department of Surgery Soonchunhyang University Seoul HospitalSeoul 04401South Korea

BACKGROUND A cutaneous ciliated cyst(CCC)is a rare,benign tumor in young female adults,which is usually found on the lower *** SUMMARY We found an uncommon location of CCC in the anterolateral cervical area and reviewed the literature.A 20-year-old female complained of a well-defined,painless,palpable mass that started several years *** mass was tense and movable and located at the anterolateral aspect of the *** showed a non-enhancing round *** excision biopsy was performed,and the cystic mass was revealed to be a *** The rare location of CCC can be found in anterior neck area,which should be another diagnostic option for mass on anterior neck.

关键词： Head and neck neoplasms Female Young adult Subcutaneous mass Mixed tumor Mullerian Case report

A case of gouty arthritis following percutaneous radiofrequency ablation for hepatocellular carcinoma

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World Journal of Gastroenterology 2010年第6期16卷 778-781页

作者： Dae hee Choi Hyo-Suk lee Department of Internal Medicine Kangwon National University College of Medicine Department of Internal Medicine and Liver Research Institute Seoul National University College of Medicine

Percutaneous radiofrequency thermal ablation(RFA) is considered an effective technique for providing local control in the majority of Hepatocellular carcinoma(HCC) *** RFA is generally well tolerated,recent studies have reported complications associated with *** describe a case of acute gouty arthritis in a 71-year-old man with chronic renal failure who was treated with RFA for a HCC lesion and who had hepatitis B-associated cirrhosis and mild renal *** surveillance of the patient detected a 3.5 cm HCC *** the patient had declined surgery,RFA was chosen for *** the third post-procedural day,the laboratory results showed increases in his uric acid and potassium levels,which were compatible with a tumor lysis syndrome. On the 6th post-procedural day,the patient complained of new right knee *** joint aspiration revealed monosodium urate monohydrate *** made the diagnosis of acute gouty arthritis arising from tumor lysis and liver infarction caused by HCC ablation,which was aggravated by acute renal insufficiency. After adequate hydration and administration of oral colchicines,the patient's right knee pain subsided andthe uric acid serum level returned to *** is the first described case of acute gouty arthritis after RFA for a HCC lesion in a patient with underlying chronic renal *** avoid hyperuricemia and an acute attack of gout after RFA therapy for HCC,early identification of patients at risk is warranted,such as those with a large tumor,rapid tumor growth,and renal insufficiency,and preventative measures should be considered.

关键词： Radiofrequency thermal ablation Hepatocellular carcinoma Gout Tumor lysis syndrome Complications

Stochastic rules for predator and prey hunting and escape behavior in a lattice-based model

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International Journal of Biomathematics 2016年第6期9卷 181-190页

作者： Wonju Jeon Sang-hee lee Department of Mechanical Engineering Korea Advanced Institute of Science and Technology Daejeon 34141 Republic of Korea Division of Integrated Mathematics National Institute for Mathematical Sciences Daejeon 34047 Republic of Korea

Understanding of ecosystem resilience and stability requires comprehending predator- prey dynamics because ecosystems consist of dynamically interacting subsystems that include predator-prey relationships. This relationship is closely related to the hunting- escaping strategies employed by the predator and prey. Therefore, understanding the effects of hunting and escaping strategies on ecosystems will lead to a better under- standing of these systems. As an approach for describing the predator-prey interaction, lattice-based models have been adopted because this approach has strong advantages for simulating various dynamical processes of individual-individual interaction. In the models, each lattice cell is either considered as an attractive/repulsive cell, or an indi- vidual cell, or else it is empty. The attractive （or repulsive cell） can be interpreted as the prey （or predator） of the individual. These states allow us to incorporate the ecological processes of local antagonistic interactions, namely the spread of disturbances （by the predator） and regrowth or recovery （by the prey）. These processes are directly related to the strategic behavior of individuals, such as hunting and escaping. In this study, we suggest a simple and effective mapping formula as a stochastic rule to describe the hunt- ing and escaping behavior. This formula could be widely used not only in the behavior but also in competitive and cooperative relationships.

关键词： Hunting and escaping behavior strategic behavior predator-prey interaction individual-based model.

Surface Patterning of Metal Zinc Electrode with an In‑Region Zincophilic Interface for High‑Rate and Long‑Cycle‑Life Zinc Metal Anode

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Nano-Micro Letters 2024年第6期16卷 192-209页

作者： Tian Wang Qiao Xi Kai Yao Yuhang Liu Hao Fu Venkata Siva Kavarthapu Jun Kyu lee Shaocong Tang Dina Fattakhova‑Rohlfing Wei Ai Jae Su Yu Department of Electronics and Information Convergence Engineering Institute for Wearable Convergence ElectronicsKyung Hee UniversityYongin‑siGyeonggi‑do 17104Republic of Korea Frontiers Science Center for Flexible Electronics(FSCFE)and Shaanxi Institute of Flexible Electronics(SIFE) Northwestern Polytechnical University(NPU)127 West Youyi RoadXi’an 710072People’s Republic of China Institute of Energy and Climate Research:Materials Synthesis and Processing(IEK‑1) Forschungszentrum Julich GmbH52425 JulichGermany School of Chemical Engineering Sungkyunkwan University2066 Seobu‑RoJangan‑GuSuwon‑siGyeonggi‑doRepublic of Korea

The undesirable dendrite growth induced by non-planar zinc(Zn)deposition and low Coulombic efficiency resulting from severe side reactions have been long-standing challenges for metallic Zn anodes and substantially impede the practical application of rechargeable aqueous Zn metal batteries(ZMBs).Herein,we present a strategy for achieving a high-rate and long-cycle-life Zn metal anode by patterning Zn foil surfaces and endowing a Zn-Indium(Zn-In)interface in the *** accumulation of electrons in the microchannel and the zincophilicity of the Zn-In interface promote preferential heteroepitaxial Zn deposition in the microchannel region and enhance the tolerance of the electrode at high current ***,electron aggregation accelerates the dissolution of non-(002)plane Zn atoms on the array surface,thereby directing the subsequent homoepitaxial Zn deposition on the array ***,the planar dendrite-free Zn deposition and long-term cycling stability are achieved(5,050 h at 10.0 mA cm^(−2) and 27,000 cycles at 20.0 mA cm^(−2)).Furthermore,a Zn/I_(2) full cell assembled by pairing with such an anode can maintain good stability for 3,500 cycles at 5.0 C,demonstrating the application potential of the as-prepared ZnIn anode for high-performance aqueous ZMBs.

关键词： Zn metal anode Surface patterning Directional Zn deposition Aqueous Zn-I_(2)batteries