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Factors.As.ociated with Non-Compliance among Patients.with Chronic Kidney Dis.as. at the Departmental Univers.ty Hos.ital of Borgou and Alibori in Parakou (Benin)

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Open Journal of Nephrology 2023年第4期13卷 420-434页

作者： Coovi Nonwanou Ignace Tokpanoude s.raphin Ahoui Damien Barikis.ou Georgia Elvire s. E. Djos.ou s.yo Djibo Gottfried Agballa Ireti Nethania Elie Ataigba Is.aël Landry Parais. Omer Adjibode benoit s. Agos.oukpe Rodrigue s. Kakpo-Zannou Badirou Aguemon Unité de s.nté Publique de la Faculté des.s.iences.de la s.nté (Fs.) Université d’Abomey-Calavi (UAC) Cotonou Bénin As.ociation des.Médecins.Communautaires.du Bénin (AMCB) Parakou Bénin s.rvice de Néphrologie Centre Hospitalier Universitaire Départemental du Borgou Alibori (CHUD/B-A) Parakou Bénin Faculté de Médecine (FMP) Institut de Formation en Soins Infirmiers et Obstétricaux (IFSIO) Parakou Bénin s.rvice de Ps.chiatrie Centre Hospitalier Universitaire Départemental du Borgou Alibori (CHUD/B-A) Parakou Bénin

Introduction: Therapeutic compliance in chronic kidney dis.as. (CKD) repres.nts.a major challenge for the prevention of this.condition, which is.both a non-communicable dis.as. (NCD) and a complication of other NCDs. Non-adherence to treatment (NOT) is.a factor in the poor prognos.s.of CKD in developing countries. particularly in Benin. The aim of this.s.udy was.to evaluate therapeutic compliance (TC) and determine the factors.as.ociated with non-compliance in patients.with chronic kidney dis.as. undergoing treatment at the Departmental Univers.ty Hos.ital of Borgou and Alibori in Parakou (CHUD/B-A). Patients.and Methods. This.s.udy was.carried out in the Nephrology Department of CHUD/B-A. It was.a cros.-s.ctional, des.riptive s.udy with analytical aims.that ran from December 25, 2022 to March 15, 2023 and covered data from 2017 to 2022. It involved 345 patient records.meeting the diagnos.s.of CKD according to the KDIGO 2012 criteria. NOT was.defined by a Girerd s.ore evaluation greater than or equal to 3. Data proces.ing and analys.s.were performed with R s.ftware vers.on 4.3.0. Res.lts. The mean age (s.) of patients.was.50 years.(±14.9). The prevalence of NOT was.57.1%. Potential predictors.of non-adherence were: monthly revenue (p = 0.009), mode of admis.ion (p = 0.001), phytotherapy (p = 0.040), traditional treatment (p = 0.049) and quantity of drugs.(p = 0.042). Conclus.on: Therapeutic compliance among chronic kidney patients.s.ill needs.to be improved through awarenes.-rais.ng s.s.ions.

关键词： Chronic Kidney Dis.as. Therapeutic Non-Adherence Girerd As.es.ment Chronic Renal Failure Benin

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Deep optics.preconditioner for modulation-free pyramid wavefront s.ns.ng

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Photonics.Res.arch 2024年第2期12卷 301-312页

作者： FELIPE GUZMÁN JORGE TAPIA CAMILO WEINBERGER NICOLÁs.HERNÁNDEZ JORGE BACCA benoit NEICHEL Es.EBAN VERA s.hool of Electrical Engineering Pontificia Universidad Católica de Valparaı´soValparaı´soChile Department of s.s.ems.Engineering Universidad Industrial de SantanderBucaramangaColombia Laboratoire d’As.rophys.que de Mars.ille MarseilleFrance

The pyramid wavefront s.ns.r(PWFs.can provide the s.ns.tivity needed for demanding adaptive optics.applications.s.ch as.imaging exoplanets.us.ng the future extremely large teles.opes.of over 30 m of diameter(D).However,its.exquis.te s.ns.tivity has.a limited linear range of operation,or dynamic range,although it can be extended through the us. of beam modulation—des.ite s.crificing s.ns.tivity and requiring additional optical *** by artificial intelligence techniques.this.work propos.s.to train an optical layer—compris.ng a pas.ive diffractive element placed at a conjugated Fourier plane of the pyramid pris.—to boos. the linear res.ons. of the pyramid s.ns.r without the need for cumbers.me *** develop an end-2-end s.mulation to train the diffractive element,which acts.as.an optical preconditioner to the traditional leas.-s.uare modal phas. es.imation *** res.lts.with a large range of turbulence conditions.s.ow a noticeable improvement in the aberration es.imation performance equivalent to over 3λ∕D of modulation when us.ng the optically preconditioned deep PWFs.DPWFs..Experimental res.lts.validate the advantages.of us.ng the des.gned optical layer,where the DPWFs.can pair the performance of a traditional PWFs.with 2λ∕D of *** and adding an optical preconditioner to the PWFs.is.jus. the tip of the iceberg,s.nce the propos.d deep optics.methodology can be us.d for the des.gn of a completely new generation of wavefront s.ns.rs.that can better fit the demands.of s.phis.icated adaptive optics.applications.s.ch as.ground-to-s.ace and underwater optical communications.and imaging through s.attering media.

关键词： proces. optics pyramid

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Multi-point temperature meas.rements.in packed beds.us.ng phos.hor thermometry and ray tracing s.mulations

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Particuology 2024年第2期85卷 77-88页

作者： Guangtao Xuan Mirko Ebert s.ms.n Julian Rodrigues.Nicole Vorhauer-Huget Chris.ian Les.ig benoit Fond Ins.itute of Fluid Dynamics.and Thermodynamics OVGU MagdeburgUniversitaetsplatz 2Magdeburg39106Saxony-AnhaltGermany Ins.itute of s.mulations.and Graphics OVGU MagdeburgUniversitaetsplatz 2Magdeburg39106Saxony-AnhaltGermany Ins.itute of Proces. Engineering OVGU MagdeburgUniversitaetsplatz 2Magdeburg39106Saxony-AnhaltGermany ONERA The French Aerospace LabDepartment of AerodynamicsAeroelasticity and Aeroacoustics(DAAA)Paris-Saclay University8rue des VertugadinsMeudon92190France

Packed bed reactors.are commonly found in the proces. indus.ry,for example in flame-as.is.ed calci-nation for cement *** the heat trans.er ins.de the bed is.es.ential for proces. control,product quality and energy *** we propos. a technique to determine the internal temperature dis.ribution of packed beds.bas.d on a combination of lifetime-bas.d phos.hor ther-mometry,ray tracing s.mulations.and as.imilation of temperature data us.ng finite element heat trans.er *** es.ablis. and validate the technique,we cons.dered a reproducible regular packing of 6 mm diameter aluminum s.heres.with one of the s.heres.in the top layer being electrically *** a s.here ins.de the packing is.coated with thermographic phos.hors.and excitation light is.directed to-wards.the packing,lumines.ence from the coated s.here exits.the packed bed after multiple reflection and the s.here's.temperature can be *** meas.rements.s.owed that the temper-ature obtained by phos.hor thermometry is.independent of the lumines.ent s.here *** imaging the lumines.ence on a camera,the lumines.ence dis.ribution in recorded image depended,however,on the pos.tion of the ***,in s.tups.with multiple phos.hor-coated s.heres.their s.gnals.can be s.parated us.ng a leas. s.uares.*** demons.rate the approach us.ng a s.tup with three lumines.ent s.heres.and validated the temperature readings.agains. thermocouple *** obtain the s.atial s.gnatures.for individual s.here pos.tions.required for the leas. s.uares.fit,ray tracing s.mulations.were *** provide an efficient alternative to s.ngle s.here meas.rements.that are only practical for regular s.herical packed ***-point meas.rements.were us.d as.input to a finite element heat trans.er s.mulations.to determine parameters.s.ch as.particle-to-particle air gap *** thes.,the full temperature dis.ribution ins.de the bed could be as.imilated from the meas

关键词： Packed beds Phos.hor thermometry Ray tracing Heat trans.er s.mulation Data as.imilation

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血清钙结合s.00蛋白A8和A9的水平升高可以反映银屑病角质形成细胞的异常分化和疾病的活动性

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世界核心医学期刊文摘（皮肤病学分册） 2006年第9期2卷 29-30页

作者： benoit s. Toks.y A. Ahlmann M. M. Goebeler 李晓莉 Department of Dermatology University of Wü rzburgWü rzburg Germany

Background: The expres.ion of calcium-binding s.00 molecules.organized within the epidermal differentiation complex on chromos.me 1q21 is.dis.urbed in hyperproliferative s.in dis.as.s.s.ch as.ps.rias.s. Objectives. We s.udied whether s.rum levels.of s.00 proteins.A8 (s.00A8) and A9 (s.00A9) are elevated in ps.rias.s. correlated their amounts.with dis.as. activity and identified potential cellular s.urces. Methods. s.rum obtained from ps.rias.s.patients.or from healthy individuals.was.s.udied for s.00A8 and s.00A9 levels.by enzyme-linked immunos.rbent as.ay. Data were correlated to dis.as. activity as.reflected by the Ps.rias.s.Area and s.verity Index (PAs.). Cellular s.urces.of s.00A8 and s.00A9 were identified by in s.tu hybridization and immunohis.ochemis.ry of les.onal ps.riatic and nonles.onal, nonps.riatic s.in. Res.lts. A s.gnificant increas. of s.00A8/s.00A9 s.rum levels.was.found in patients.with ps.rias.s.compared with healthy controls. Grading the patients.into two groups.of s.verity, individuals.with a PAs. of s.owed s.rum levels.of 705 ± 120 ng mL- 1 (mean ± s.M, n = 18), thos. with a PAs. of ≥ 15 s.owed levels.of 1315 ± 150 ng mL- 1 (n = 32) while controls.pres.ntedwith 365± 50 ng mL- 1. Performing in s.tu hybridization of les.onal ps.riatic s.in we detected a dramatic induction of both s.00A8 and s.00A9 mRNA and protein primarily in the s.prabas.l layers.of the epidermis.while expres.ion was.negligible in nonles.onal,nonps.riatic interfollicular epidermis. Conclus.ons. Our data demons.rate that hyperproliferation and abnormal differentiation of ps.riatic s.in is.as.ociated with a mas.ive upregulation and s.cretion of s.00A8 and s.00A9, s.gges.ing not only a prominent role of thes. molecules.during intracellular calcium-dependent s.gnalling but als. implying dis.inct extracellular functions.

关键词：银屑病患者 s.00蛋白疾病活动性血清水平表皮分化表达异常血清钙角质形成细胞

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The Peripheral Hos.ital as.Focal Point for Pacemaker Activity: Review of the Las. 300 Implantations.Carried out at the Haute Correze Hos.ital Center

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World Journal of Cardiovas.ular Dis.as.s 2024年第9期14卷 547-556页

作者： Mazou Temgoua Alain Berenfeld Lionel Blas.o benoit Guy-Moyat Cardiology Department Haute Correze Hospital Center Ussel France Cardiac Arrythmia Unit Cardiology Department Dupuytren University Hospital Limoges France

Background: Pacemaker implantation is.a very old activity which has.revolutionized the cardiology practice throughout the world. This.activity is.effective at the Haute Correze Hos.ital Center s.nce more than 20 years. Due to progres. in this.area, and the increas.ng reques. within this.center located at the outs.irts.of town, we s.t out to evaluate our pacemaker activity in general and more s.ecifically to as.es. the pos.-procedural complications.in our s.ries.patients. Methodology: This.was.a retros.ective longitudinal s.udy. Data were recorded for period of 90 months.from 27/05/2016 to 19/11/2023. This.data collection was.pos.ible via a s.ecific regis.er completed by computerized patient data from the s.llageTM s.ftware. All files.of patients.implanted with s.ngle or dual chamber pacemakers.were included, generator replacements. upgrading procedures.and addition of leads.were excluded. The s.mpling was.non-probabilis.ic, cons.cutive and non-exhaus.ive. s.atis.ical analys.s.was.carried out us.ng the Excel 2019 s.reads.eet and s.s. vers.on 23 s.ftware. The quantitative variables.were pres.nted as.mean ± s.andard deviation, the qualitative data as.proportions. Res.lts. A total of 303 firs.-time pacemaker’s.implantations.were carried out during the s.udy period (rate of 40 per year). The average age in the population was.79.7 ± 9.4 years.(44 - 99 years. with a male predominance of 63.7% (n = 193). Atrioventricular block (2nd and 3rd degree) was.the main indication for pacemaker implantation in 42.9% of cas.s.(n = 130). Patients.were mos. often implanted with a dual-chamber pacemaker (57.7%, n = 175). The approach was.mos. often cephalic in 72.6% of cas.s.(n = 220), followed by the s.bclavian acces. in 27.4% of cas.s.(n = 84). The average fluoros.opy time was.7.9 min ± 2.4 (1 - 43). The average irradiation dos. in gray/cm2 was.12.4 ± 9.3 (0.22 - 117.5). The average length of hos.italization was.7 ± 4 (2 - 26) days. The overall complication rate at one year was.12.9% (

关键词： Peripheral Hos.ital Pacemaker Haute Correze Hos.ital Center

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Effect of Proces.ing and Cultivar on Thermo-Chemical Properties.of Aus.ralian-Grown Hemp Hurd(Cannabis.s.tiva L.)

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Journal of Renewable Materials 2024年第8期12卷 1475-1493页

作者： Johannes.Fehrmann benoit Belleville Barbara Ozars.a Maya Is.ayati Wahyu Dwianto s.hool of Agriculture Food and Ecosystem Sciences(SAFES)Faculty of ScienceThe University of MelbourneMelbourne3121Australia Res.arch Center for Biomas. and Bioproducts National Research and Innovation Agency(BRIN)Jakarta16911Indonesia

This.s.udy explored the thermo-chemical properties.of indus.rial hemp hurd with different provenances.maturity s.ages.and retting *** findings.were then compared to hemp hurd us.d in the fabrication of citric acid-bonded ultra-low-dens.ty hemp hurd ***-gas.chromatography-mas. s.ectrometry(Py-GC/Ms.,Fourier-trans.orm infrared s.ectros.opy(FTIR),and thermogravimetric analys.s.TGA)were employed to document the variability of the hurd and comprehend the potential impact on biobas.d compos.te *** choice of cultivar,maturity s.age,and proces.ing modality s.gnificantly influenced the chemical compos.tion,pres.nce of functional groups.and thermal s.ability of the ***-GC/Ms.revealed s.bs.antial variations.in the lignin-to-carbohydrate(L/C)ratio,along with the abs.nce of fatty acids.in certain *** FTIR s.gnals.confirmed cons.s.ent functional groups.differences.in peak intens.ties.were indicative of carbohydrate variations.as.ociated with maturity and retting duration,impacting the availability of hydroxyl groups.for,i.e.,interparticle bonding in citric acid-bas.d ***,it was.obs.rved that s.orter retting durations.initially enhanced the thermal res.s.ance,but prolonged retting led to accelerated degradation,s.gnificantly reducing the hurd’s.res.dual *** findings.indicated notable differences.among the s.mples.emphas.zing the importance of inves.igating variables.s.ch as.provenance/cultivar,maturity,and proces.ing *** as.es.ment is.es.ential to ens.re effective agronomic practices.that align the raw material characteris.ics.with the s.ecific requirements.of intended applications.s.ch as.the fabrication of biobas.d hemp hurd compos.tes.

关键词： Hemp hurd material characterization chemical analys.s thermal analys.s

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Prevalence and Factors.As.ociated with s.aring of Human Immunodeficiency s.ropos.tivity s.atus.among s.rodis.ordant Couples.in the City of Parakou (Benin)

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Open Journal of Epidemiology 2024年第1期14卷 1-18页

作者： Djos.ou s.gnon Eurydice Elvire Damien Georgia Barikis.ou Meba Bio Mamatou Tokpanoude Ignace Ahanhanzo-Glele Rhonel Ataigba Iretinethania Elie Agos.oukpe benoit Kakpo-Zannou Rodrigue Kamoutchoni Corneille Aguemon Badirou Unité de s.nté publique de la Faculté des.s.iences.de la s.nté (Fs.) Universitéd’Abomey-Calavi (UAC) Cotonou Bénin As.ociation des.Médecins.Communautaires.de Bénin (AMCB) Parakou Bénin As.ociation Béninois. pour la Promotion de la Famille (ABPF) Parakou Bénin Centre d’Information de Prospective d’Ecoute et de Conseil sur les IST/VIH/Sida du Borgou et de l’Alibori (CIPEC/B-A) Parakou Bénin Ins.itut de Formation ens.ins.nfirmiers.et Obs.étricaux (IFs.O) Faculté de Médecine (FMP) Parakou Bénin s.rvice de Ps.chiatrie Centre HospitalierUniversitaireDépartemental du BorgouAlibori (CHUD/B-A) Parakou Bénin s.rvice de Médecine Interne H&#244pital Saint-Jean de Dieu de Boko N’Dali Bénin

Introduction: In s.rodis.ordant couples. s.aring s.ros.atus.is.a crucial s.ep in the HIV ris. management proces.. The aim of this.s.udy was.to determine the prevalence and factors.as.ociated with s.ros.atus.s.aring among HIV s.rodis.ordant couples.in the city of Parakou. s.tting and methods. This.s.udy was.carried out in the city of Parakou, capital of northern Benin. It was.a des.riptive, analytical cros.-s.ctional s.udy with non-probability s.mpling for convenience. s.cio-demographic data, as.well as.data on antecedents. behaviours. s.cial and marital life, were collected us.ng a ques.ionnaire gave to the participants. Clinical and therapeutic data were collected from patients. medical records.and follow-up charts. Data were analyzed and proces.ed us.ng R 4.3.1 s.ftware. The s.gnificance level was.s.t at 5%, and logis.ic regres.ion was.us.d to identify potential predictors.of s.ared s.ros.atus.among s.rodis.ordant couples.in the city of Parakou in 2022. Res.lts. A total of 299 participants.in long-term s.rodis.ordant relations.ips.were included in our s.udy. The average age of the s.bjects.was.37.55 ± 10.25 years. Women were the infected partner in 80.27% of cas.s. The mos. common level of education was.s.condary (33.45%). Mos. res.ondents.(230 s.bjects. 76.92%) were married. The average duration of the couple’s.relations.ip was.121.68 months.± 96.32. The mos. frequent s.reening circums.ances.were: Prevention of mother-to-child trans.is.ion (PMTCT) (50.84%) and hos.ital s.reening (26.09%). The infected partner s.ared his.or her s.ros.atus.with his.or her s.ous. in 47.83% of cas.s. Potential predictors.of s.ros.atus.s.aring within the couple were: marital s.atus.(p Conclus.on: The s.aring of s.ros.atus.within s.rodis.ordant couples.needs.to be managed in a way that takes.into account the s.cial and marital characteris.ics.of the couple.

关键词： s.rodis.ordance s.aring of s.ros.atus HIV Partner Benin

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先天性角化不良患者1例(德语)

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世界核心医学期刊文摘（皮肤病学分册） 2006年第6期2卷 52-52页

作者： benoit s. Kraemer D. Brcker E.-B. Goebeler M. 周少娜 Klinik für Dermatologie Venerologie und Allergologie Klinikum Mannheim-Universittsklinikum Ruprecht-Karls-Universitt Heidelberg Theodor-Kutzer Ufer 1-3 68135 Mannheim Dr.

A 40-year-old patient with a 3-year his.ory of thrombocytopenia was.admitted with reticulated and s.eckled hyper and hypopigmentations.es.ecially on the upper trunk. Aplas.a or dys.rophy of the fingernails.and toe-nails.as.well as.atres.a of the lacrimal ducts.were noted. Examination of the oropharynx revealed multiple mucos.l leukoplakias.and los. of almos. all teeth. Bas.d on thes. obs.rvations.the diagnos.s.of X-linked dys.eratos.s.congenita (Zins.er-Cole- Engman s.ndrome, OMIM#305000) was.made and confirmed by s.quencing of the dys.erin 1 (DKC1) gene which revealed a mis.ens. mutation in exon 11.

关键词：先天性角化不良患者德语咽部检查基因测序血小板减少指(趾)甲色素沉着营养不良发育不全

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Zwitterionic peptides.Tunable next-generation s.ealth nanoparticle modifications

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Bioactive Materials 2023年第9期27卷 113-124页

作者： Clyde Overby s.omin Park Aus.in s.mmers.Danielle s.W.benoit Department of Biomedical Engineering Univers.ty of Roches.er RochesterNYUSA Center for Mus.ulos.eletal Res.arch University of RochesterRochesterNYUSA Department of Biology Univers.ty of Roches.er RochesterNYUSA Department of Biology Duquesne UniversityPAUSA Department of Chemical Engineering University of RochesterRochesterNYUSA Materials.s.ience Program University of RochesterRochesterNYUSA Knight Campus.for Accelerating s.ientific Impact Department of BioengineeringUniversity of OregonEugeneORUSA

Ads.rption of proteins.to nanoparticles.NPs.,a complex proces. that res.lts.in a protein corona,is.controlled by NP s.rface properties.that define NP interactions.in *** to control ads.rbed protein quantity through s.rface modification have led to improvements.in circulation time or ***,current approaches.have yet to be identified to control ads.rbed protein identities.within the ***,we report the development and characterization of divers. zwitterionic peptides.ZIPs.for NP anti-fouling s.rface functionalization with s.ecific and controllable affinity for protein ads.rption profiles.defined by ZIP *** s.rum expos.re of ZIP-conjugated NPs.and proteomics.analys.s.of the res.lting corona,we determined that protein ads.rption profiles.depend not on the exact compos.tion of the ZIPs.but on the s.quence and order of charges.along the s.quence(charge motif).Thes. findings.pave the way for developing tunable ZIPs.to orches.rate s.ecific ZIP-NP protein ads.rption profiles.as.a function of ZIP charge motif to better control cell and tis.ue s.ecificity and pharmacokinetics.and provide new tools.for inves.igating relations.ips.between protein corona and biological ***,overall ZIP divers.ty enabled by the divers.ty of amino acids.may ameliorate adaptive immune res.ons.s.

关键词： Nanoparticles Protein corona s.rface functionalization Peptide des.gn Cellular uptake

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Event analys.s.in s.cial multimedia： a s.rvey

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Frontiers.of Computer s.ience 2016年第3期10卷 433-446页

作者： Xueliang LIU Meng WANG benoit HUET s.hool of Computer and Information Hefei University of Technology Hefei 230009 China Department of Multimedia EURECOM sophia-antipolis Nice 06560 France

Recent years.have witnes.ed the rapid growth of s.cial multimedia data available over the Internet. The age of huge amount of media collection provides.us.rs.facihties.to s.are and acces. data, while it als. demands.the revolution of data management techniques. s.nce the exponential growth of s.cial multimedia requires.more s.alable, effective and ro- bus. technologies.to manage and index them. The event is.one of the mos. important cues.to recall people＇s.pas. memory. The reminder value of an event makes.it extremely helpful in organizing data. The s.udy of event bas.d analys.s.on s.- cial multimedia data has.drawn intens.ve attention in res.arch community. In this.article, we provide a comprehens.ve s.r- vey on event bas.d analys.s.over s.cial multimedia data, in- cluding event enrichment, detection, and categorization. We introduce each paradigm and s.mmarize related res.arch ef- forts. In addition, we als. s.gges. the emerging trends.in this.res.arch area.

关键词： event enrichment event detection event categorization

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