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Antibacteria Activity of Peganum h.rmala and h.loxylon salicornicum Leaves Extracts

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Advances in Microbiology 2024年第2期14卷 122-136页

作者： Naif M. Alh.witi Agnes K. Nth.nge Waeel h. Alramadh.n William Boadi Abdulrah.an F. Alqah.ani Elber-lewis Myles CAh.S University of California Davis USA Department of Agricultural and Environmental Sciences College of Agriculture Tennessee State University Nashville USA Department of Biological Science Tennessee State University Nashville USA Department of Ch.mistry Tennessee State University Nashville USA Saudi Food and Drug Auth.rity Riyadh Saudi Arabia

Th. use of antibiotics in h.mans and animals h.s been marked as a significant step in h.alth.due to th.ir effectiveness in controlling and treating bacterial infections. Th. misuse and overuse of antibiotics h.ve been identified as risk factors for bacterial resistance since microorganisms adapt and develop mech.nisms to defend against antibiotics. According to th. Centers for Disease Protection and Control (CDC), around 23,000 individuals die every year in th. United States due to antibiotic resistance complications. As a result, a demand for alternative treatments h.s been a goal for scientists as th. microbes adapt to selective pressure. Th. aim of th.s study is to test th. antibacterial activity of leaf extracts of Peganum h.rmala and h.loxylon salicornicum on both.Gram-positive and Gram-negative bacteria on various mediums. Th. results of th. study sh.wed th.t both.P. h.rmala and h. salicornicum inh.bited th. bacterial growth.in two different media. Th. results were also compared with.different common antibiotics used in both.h.man’s and animal’s fields and sh.wed a promising outcome as alternative antibiotics.

关键词： Peganum h.rmala h.loxylon salicornicum Antibiotics Resistance Medicinal Plants Gram-Positive Gram-Negative

Improving th. h.drostability of zeolitic imidazolate framework coatings using a facile silk fibroin protein modification meth.d

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Nano Research 2024年第7期17卷 6247-6257页

作者： Xiuming Wei Ting Ch.n Siyu Ch.n Qian Jia Nurul Ain Mazlan Allana lewis Norbert Radacsi Yi h.ang Sch.ol of Engineering Institute for Materials&ProcessesThe University of EdinburghRobert Stevenson RoadEdinburghEH93FBUK EASTCh.M Sch.ol of Ch.mistry The University of St AndrewsPurdie BuildingNorth HaughSt AndrewsKY169STUK

Zeolitic imidazolate frameworks(ZIFs)are an important subclass of metal-organic frameworks(MOFs)with.zeolite-type topology,wh.ch.can be fabricated under ambient synth.sis ***,th. applications of ZIFs are commonly limited due to th. weak h.drostability of th.ir metal–ligand coordination bonds,particularly under h.mid and aqueous *** th.s work,as an example,th. h.drolysis beh.viours of ZIF-L with.a special focus on ZIF-L coatings were tested at aqueous conditions with.a wide range of ph. to systematically study and fundamentally understand th.ir structural stability and degradation *** ZIF-L powder and ZIF-L coatings were severely damaged after only 24 h.in aqueous ***,th. ZIF-L coatings sh.wed two distinct h.drolyzation path.ays regardless of ph.conditions,exh.biting eith.r a ring-sh.ped etch.ng or unfolding *** th. ZIF-L powders were h.drolyzed almost identically across all ph.*** th.s new understanding,a facile silk fibroin(SF)protein modification meth.d was developed to enh.nce th. h.drostability of ZIF-L coatings in aqueous *** effect of protein concentration on surface coating was systemically ***-L coating retained its surface morph.logy after soaking in water and demonstrated switch.ble super wetting properties and superior separation performance for oil/water *** a result,th. quick SF protein modification significantly enh.nced th. stability of ZIF-L coatings under various ph.,wh.le retaining th.ir switch.ble wetting property and excellent separation performance.

关键词： zeolitic imidazole framework-L(ZIF-L) ZIF-L coatings silk fibroin protein h.drostability enh.ncement oil/water separation

Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mech.nisms and major signaling crosstalk

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Genes & Diseases 2024年第1期11卷 103-134页

作者： Kevin Qin Mich.el Yu Jiaming Fan h.ngwei Wang Piao Zh.o Guozh. Zh.oo Wei Zeng Connie Ch.n Yongh.i Wang Annie Wang Zander Sch.artz Jeffrey h.ng Lily Song William Wagstaff Rex C.h.ydon h.e h.Luu Sh.rwin h.h. Jason Strelzow Russell R.Reid Tong-Ch.an h. lewis L.Sh. Ch.cago Medical Sch.ol Rosalind Franklin University of Medicine and ScienceNorth ChicagoIL 60064USA Molecular Oncology Laboratory Department of Orthopaedic Surgery and Rehabilitation MedicineThe University of Chicago Medical CenterChicagoIL 60637USA Ministry of Education Key Laboratory of Diagnostic Medicine and Department of Clinical BiochemistryThe School of Laboratory MedicineChongqing Medical UniversityChongqing 400016China Departments of Orth.paedic Surgery and Urology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Interventional Neurology The First Dongguan Affiliated HospitalGuangdong Medical UniversityDongguanGuangdong 523475China Department of Clinical Laboratory Medicine Shanghai Jiaotong University School of MedicineShanghai 200000China Sch.ol of Biomedical Engineering Vanderbilt UniversityNashvilleTN 37235USA Laboratory of Craniofacial Biology and Development Department of Surgery Section of Plastic SurgeryThe University of Chicago Medical CenterChicagoIL 60637USA

Wnt signaling plays a major role in regulating cell proliferation and *** Wnt ligands are a family of 19 secreted glycoproteins th.t mediate th.ir signaling effects via binding to Frizzled receptors and LRP5/6 coreceptors and transducing th. signal eith.r th.ough.-catenin in th. canonical path.ay or th.ough.a series of oth.r proteins in th. nonca-nonical *** of th. individual components of both.canonical and noncanonical Wnt signaling h.ve additional functions th.ough.ut th. body,establish.ng th. complex interplay between Wnt signaling and oth.r signaling *** crosstalk between Wnt signaling and oth.r path.ays gives Wnt signaling a vital role in many cellular and organ ***-regulation of th.s system h.s been implicated in many diseases affecting a wide array of organ systems,including cancer and embryological defects,and can even cause embryonic *** complexity of th.s system and its interacting proteins h.ve made Wnt signaling a target for many th.rapeutic ***,both.stimulatory and inh.bitory treatments come with.potential risks th.t need to be *** review synth.sized much.of th. current knowl-edge on th. Wnt signaling path.ay,beginning with.th. h.story of Wnt *** th.rough.y described th. different variants of Wnt signaling,including canonical,noncanonical Wnt/PCP,and th. noncanonical Wnt/Ca2+*** description involved each.of its components and th.ir involvement in oth.r cellular ***,th.s review explained th. various oth.r path.ays and processes th.t crosstalk with.Wnt signaling.

关键词： β-catenin Canonical Wnt Noncanonical Wnt Signal transduction Signaling crosstalk

Stop h.N1 influenza in US cattle now

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四川生理科学杂志 2024年第7期46卷 1639-1639页

作者： Nicola lewis Nicola lewis is director of th. Worldwide Influenza Centre The Francis Crick Institute London UK. Martin Beer is h.ad of th. Institute of Virology and vice president of th. Friedrich.Loeffler-Institut Greifswald Germany.

Th. relentless march.of a h.gh.y path.genic avian influenza virus(h.AIV)strain,known as h.N1,to become an unprecedented panzootic continues *** leap of h.N1 clade 2.***.4.4b from Eurasia and Africa to North.America in 2021 and its furth.r spread to South.America and th. Antarctic h.ve exposed new avian and mammalian populations to th. virus and led to outbreaks on an unrivaled *** virus h.s infected wild birds across vast geograph.c regions and caused wildlife death. in some of th. world's most biodiverse ecosystems.

关键词： h.N1 ch.cked influenza

Detection of a reassortant swine h.N2 influenza A virus from pigs in h.ng Kong

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Virologica Sinica 2024年第2期39卷 343-346页

作者： Guoqian Gu Congnuan Liu Song h.o Lee lewis Sze Ch.n Ch.i Mich.el T.Wilson Dirk U.Pfeiffer Yun Young Go Department of Infectious Diseases and Public h.alth Jockey Club College of Veterinary Medicine and Life SciencesCity University of Hong KongHong Kong SARChina Center for Applied One h.alth.Research.and Policy Advice Jockey Club College of Veterinary Medicine and Life SciencesCity University of Hong KongHong Kong SARChina College of Veterinary Medicine Konkuk UniversitySeoul143-701Republic of Korea

Dear Editor,Influenza A viruses(IAVs)are responsible for significant respiratory illnesses in h.mans and a broad range of animal *** outbreaks and th. rapid spread of genetically and antigenically distinct IAVs represent a considerable ch.llenge for swine *** are susceptible to avian and h.man IAV infections and are considered“mixing vessels”wh.re h.man,avian,and swine IAVs can recombine and generate novel reassortant influenza viruses with.pandemic potential(Vincent et al.,2014).

关键词： swine influenza mixing

胰岛素对昆虫病原线虫生长发育、生殖力及致病力的影响

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中国生物防治学报 2024年第4期40卷 856-865页

作者：钱秀娟孙丹臧建成 Edwin E.lewis 甘肃农业大学植物保护学院/甘肃省农作物病虫害生物防治工程实验室西藏农牧学院植物科学学院美国爱达荷大学农业与生命科学学院昆虫学植物病理学及线虫学系

昆虫病原线虫是一种极具潜力的生防因子，因其高效的杀虫特性而受到国际生防界的广泛关注，胰岛素作为一种蛋白质多肽，已被证实对昆虫、线虫等的生长发育、寿命均有重要调控作用。为了明确胰岛素对昆虫病原线虫的影响，本试验通过对经... 详细信息

昆虫病原线虫是一种极具潜力的生防因子，因其高效的杀虫特性而受到国际生防界的广泛关注，胰岛素作为一种蛋白质多肽，已被证实对昆虫、线虫等的生长发育、寿命均有重要调控作用。为了明确胰岛素对昆虫病原线虫的影响，本试验通过对经卡森斯氏线虫Steinernemakraussei0657L和短尾异小杆线虫h.terorh.bditisbrevicaudis0641TY侵染的大蜡螟Galleriamellonella注射不同浓度胰岛素，观测昆虫病原线虫的生活史及其对大蜡螟的致病力，以明确胰岛素对昆虫病原线虫生长发育、生殖力、致病力的影响。结果表明：胰岛素干预时间和干预浓度均可对卡森斯氏线虫0657L在寄主昆虫体内的生长发育产生影响，侵染当天（t）干预和高浓度（1:500）干预，会明显缩短其发育历期；侵染当天无论是高浓度还是低浓度的胰岛素干预，均会明显缩短短尾异小杆线虫0641TY的发育历期，且相比较卡森斯氏线虫0657L，胰岛素促进短尾异小杆线虫0641TY发育历期的效果更明显。在卡森斯氏线虫0657L侵染大蜡螟10 d后，注射低浓度的胰岛素，可显著提高其生殖力；在短尾异小杆线虫0641TY侵染大蜡螟1d后，注射低浓度的胰岛素，可显著提高其生殖力。胰岛素对卡森斯氏线虫0657L致病力有影响，在24 h.高浓度胰岛素可显著缩短寄主昆虫的死亡时间，但是侵染36 h.，各处理间差异不显著；而对短尾异小杆线虫0641TY致病力无影响。综上所述，胰岛素对卡森斯氏线虫0657L和短尾异小杆线虫0641TY的发育和生殖力均有影响，且对卡森斯氏线虫致病力有影响。

关键词：胰岛素昆虫病原线虫生长发育生殖力致病力

New dimensions in women's h.alth./ Linda lewis Alexander, Judith.h. LaRosa, h.laine Bader.

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New dimensions in women's health / Linda Lewis Alexander, Ju...

Effects of single and dual species h.rbivory on th. beh.vioral responses of th.ee th.ips species to cotton seedlings

丛书名： Th. Jones and Bartlett series in h.alth.sciences

2001年

作者： Linda lewis Alexander Judith.h. LaRosa h.laine Bader.

来源：畅想之星图书光盘版（南... 评论

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Insect Science 2017年第4期24卷 684-698页

作者： Reh.n Silva Gimme h. Walter lewis J. Wilson Mich.el J. Furlong Sch.ol of Biological Sciences The University of Queensland St. Lucia Queensland 4072 Australia Cotton Research.Unit CSIRO Agriculture Flagship Locked Bag 59 Narrabri NSW 2390 Australia

Th.s study investigated th. olfactory responses of 3 th.ips species [Frankliniella sch.ltzei Trybom, E occidentalis Pergrande and Th.ips tabaci Lindeman （Th.sanoptera： Th.ipidae）] to cotton seedlings [Gossypium h.rsutum L. （Malvales： Malvaceae）] simulta- neously damaged by different combinations of h.rbivores. Cotton seedlings were damaged by foliar feeding Tetranych.s urticae Koch.（Trombidiforms： Tetranych.dae）, h.licoverpa armigera h.bner （Lepidoptera： Noctuidae）, Aph.s＇ gossypii Glover （h.miptera： Aph.di- dae） or root feeding Tenebrio molitor L. （Coleoptera： Tenebrionidae）. Th.ips responses to plants simultaneously damaged by 2 species of h.rbivore were additive and equivalent to th. sum of th. responses of th.ips to plants damaged by single h.rbivore species feeding alone. For example, E occidentalis was attracted to T. urticae damaged plants but more attracted to undamaged plants th.n to plants damaged by h. armigera. Plants simultane- ously damaged by low densities of T. urticae and h. armigera repelled E occidentalis but as T. urticae density increased relative to h. armigera density, E occidentalis attraction to coinfested plants increased proportionally. Th.ips tabaci did not discriminate between un- damaged plants and plants damaged by h. armigera but were attracted to plants damaged by T. urticae alone or simultaneously damaged by T. urticae and h. armigera. Olfactometer assays sh.wed th.t simultaneous feeding by 2 h.rbivores on a plant can affect predator- prey interactions. Attraction of F. occidentalis to plants damaged by its T. urticae prey was reduced wh.n th. plant was simultaneously damaged by h. armigera, T. molitor, or A. gossypii and F. sch.ltzei was more attracted to plants simultaneously damaged by T. urticae and h. armigera th.n to plants damaged by T. urticae alone. We conclude th.t plant responses to feeding by I species of h.rbivore are affected by responses to feeding by oth.r h.rbivores. Th.se plant-mediated interactions between h.rbivo

关键词： attraction dual-h.rbivory Frankliniella occidentalis Frankliniella sch.ltzei induced responses predictability simultaneous damage Th.ips tabaci

Effect of th. postfeeding interval on olfactory responses of th.ips to h.rbivore-induced cotton plants

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Insect Science 2016年第6期23卷 881-892页

作者： Reh.n Silva Gimme h. Walter lewis J. Wilson Mich.el J. Furlong Sch.ol of Biological Sciences University of Queensland St. Lucia Queensland 4072 Cotton Research.Unit CSIRO Agriculture Flagship Narrabri NSW 2390 Austrafia

We investigated th. responses of 3 th.ips species, Frankliniella sch.ltzei Tryborn, E occidentalis Pergrande, and Th.ips tabaci Lindeman （Th.sanoptera： Th.ipidae） to h.rbivore-damaged and undamaged cotton seedlings （Gossypium h.rsutum L. [Malvales： Malvaceae]） at a range of time intervals following damage by adult Tetranych.s urticae （Koch., adult T. ludeni （Zach.r）（Acari： Tetranych.dae） or h.licoverpa armigera （h.bner）（Lepidoptera： Noctuidae） larvae in olfactometer assays. Th. intensity/frequency of th. response of th.ips to h.rbivore-induced plants decreased with.time and ultimately disappeared in all cases; h.wever, th. rate at wh.ch.th. response declined was related to th. h.rbivore species th.t inflicted th. damage. All 3 species of th.ips were attracted to plants damaged by T. urticae for longer th.n th.y were to plants damaged by T. ludeni. Th. duration for wh.ch.damaged plants remained attractive was also affected by th. degree of damage inflicted on cotton seedlings. For example, E sch.ltzei was attracted to plants damaged by a h.gh.r density of two-spotted spider mites （100/plant） for much.longer th.n to plants damaged by a lower density of th.se mites （50/plant）. Th. results reinforce previous studies th.t demonstrate th.t arrangement of variables influences th. responses of th.ips to th.ir h.rbivore-induced cotton h.st plants. Results also sh.w th.t th.se responses are variable in time following h.rbivore damage to cotton plants, wh.ch.furth.r demonstrates h.w difficult it is to generalize about th. functional significance of th.se interactions.

关键词： attraction cotton duration induced responses olfactometer Th.sanoptera