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发作性晕厥胸闷

中国实用内科杂志 2009年第8期29卷 756-758页

作者：白英史旭波王吉云马志敏陈喆许毓申柳志红许玉韵北京同仁医院北京100730 北京阜外心血管病医院北京100052 北京大学人民医院北京100044

1病历资料患者老年男性,80岁.主因"间断头晕30余年,发作性晕厥2年,加重5h"于2008-07-28收入北京同仁医院心血管病中心.既往史:右下肢静脉曲张术后1年余;发现阵发性心房颤动(简称房颤)2年,规律口服华法林抗凝(2.5mg/d)治疗1年,INR控制在2-3.

关键词：晕厥胸闷起搏器术后肺栓塞心功能不全

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热休克蛋白70与经瞳孔温热疗法实验研究

临床和实验医学杂志 2007年第4期6卷 1-3页

作者：王宏彬彭晓燕李志华李志辉阎伟熊颖首都医科大学附属北京友谊医院眼科北京100050 北京同仁眼科中心北京100730

目的探讨经瞳孔温热疗法(TTT)对眼组织热休克蛋白70(HSP70)表达的影响。方法利用恒河猴做动物模型。于治疗后不同时间点(1天,1周,2周,1个月)摘除双眼。应用组织学及免疫组化技术,研究TTT治疗对HSP70的影响。结果TTT治疗后,于1天起,在强... 详细信息

目的探讨经瞳孔温热疗法(TTT)对眼组织热休克蛋白70(HSP70)表达的影响。方法利用恒河猴做动物模型。于治疗后不同时间点(1天,1周,2周,1个月)摘除双眼。应用组织学及免疫组化技术,研究TTT治疗对HSP70的影响。结果TTT治疗后,于1天起,在强反应光斑边缘视网膜,脉络膜有热休克蛋白70的表达,一月时视网膜全层萎缩,激光斑边缘仍可见HSP70表达,TTT治疗可以引起视网膜不同程度组织病理学的损害。结论经瞳孔温热疗法可以引起恒河猴视网膜组织病理学损害。局部温度的升高会诱导猴眼视网膜脉络膜内源性HSP70的产生,从而提高细胞的耐热能力,达到减少组织细胞损伤的目的。

关键词：瞳孔温热疗法热休克蛋白眼组织表达视网膜

数据同化谱写陆面过程研究中理论模型与观测数据的和弦

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科学通报 2024年第15期69卷 1973-1975页

作者：徐同仁张刚强北京师范大学地理科学学部地表过程与资源生态国家重点实验室北京100875

陆面数据同化通过融合理论模型和观测数据,为科学家们提供了一个强大的工具,以更准确地模拟和预测土壤湿度、积雪、蒸散发、径流、地下水、农业灌溉、湍流通量、陆表温度、植被动态、作物产量等地表过程关键参量[1~4].数据同化如同一把... 详细信息

陆面数据同化通过融合理论模型和观测数据,为科学家们提供了一个强大的工具,以更准确地模拟和预测土壤湿度、积雪、蒸散发、径流、地下水、农业灌溉、湍流通量、陆表温度、植被动态、作物产量等地表过程关键参量[1~4].数据同化如同一把钥匙,开启了对地球系统科学深入理解的大门.

关键词：数据同化地球系统科学地表过程融合理论土壤湿度湍流通量陆面过程理论模型

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Retinoblastoma in a young adult mimicking Coats'disease

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International Journal of Ophthalmology(English edition) 2012年第5期5卷 625-629页

作者： Zheng Zhang, Ji-Tong Shi, Ning-Li Wang, Jian-Min Ma beijing tongren Eye Center, beijing tongren hospital, Capital Medical University, beijing Ophthalmology & Vision Science Key Lab, beijing 100730, china beijing tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing Ophthalmology & Vision Science Key Lab Beijing 100730 China.

Retinoblastoma is the most common childhood primary intraocular malignancy, with the majority of cases being diagnosed before 5 years of age. Retinoblastoma in adults is extremely rare. Here, we report the case of a 20-year-old man who presented with a 3 year history of blurred vision in the right eye. Imaging did not reveal the typical presentation of retinoblastoma. After considering Coats’ disease, a diagnosis of late-presenting retinoblastoma was made through cytological analysis. Diagnosis of retinoblastoma should be considered in the presence of uncertain mass lesions in the fundus of an adult.

关键词： adult retinoblastoma Coats'disease cytological analysis

Warthin-starry Silver Method Showing Particulate Matter in Macrophage

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Biomedical and Environmental Sciences 2008年第1期21卷 85-89页

作者： HONG-GANG LIU Department of Pathology Beijing Tongren Hospital Capital Medical University Beijing 100730 China

Objective To verify whether Warthin-Starry （WS） silver method could detect the air particulate matter （PM）/dust particles （Ps） located within the macrophages in situ. Methods There were 26 autopsy cases that resulted from cerebral hemorrhage （group A）, silicosis （group B）, and fetal death during pregnancy （group C）. Samples were collected separately and serial sections were prepared from the lungs and lymph nodes and stained with hematoxylin and eosin （HE）, WS silver, immunohistochemistry of CD68. Furthermore, ultrathin sections were taken from the WS positive serial sections of groups A and B. Ps were observed under a transmission electron microscope （TEM） and the elements of Ps were measured by X-ray spectrum analysis （X-RSA）. Results In both groups A and B, WS staining was positive for the larger and fine Ps, the so called ＂dust cells＂, but HE staining was almost negative for fine Ps. In group C, no larger or fine Ps were found. Immunohistochemical staining of CD68 certified that the ＂dust cells＂ containing Ps were macrophages. The results of TEM and X-RSA proved that the structure and elements of Ps belonged to PM indeed. Conclusion WS staining is a better than HE staining in showing the location of PM within macrophages.

关键词： Fine particulate matter Warthin-Starry stains Macrophage Dust cell

Protective effect of liver ischemic preconditioning on rat hepatocytes

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Science china(Life Sciences) 2009年第9期52卷 836-840页

作者： FU JianZhu1,2,WANG Yu1,ZHANG LiJun2 & YU ZeLi2 1 Department of General Surgery,beijing Friendship hospital,Capital Medical University,beijing 100050,china 2 Department of General Surgery,beijing tongren hospital,Capital Medical University,beijing 100730,china Department of General Surgery Beijing Friendship Hospital Capital Medical University Beijing China Department of General Surgery Beijing Tongren Hospital Capital Medical University Beijing China

Ischemic preconditioning (IPC) protects liver graft function following ischemia in liver transplantation and liver resection. The aim of this study was to assess the advantages and any potential disadvantages of liver IPC prior to isolation for rat hepatocytes during isolation and cryopreservation. After isolating and thawing the cryopreserved hepatocytes after 14 and 28 d,cell viability,efficiency,and lactate dehydrogenase (LDH) levels in preserve solution were examined for every group. Groups treated with IPC had better cell viability determination,assessment of plating efficiency and lactate dehydrogenase (LDH) assay than Group without IPC,suggesting that IPC prior to isolation may have a significant protective effect on hepatocytes subjected to isolation and short period cryopreservation.

关键词： liver ischemic preconditioning hepatocytes cryopreservation

Anomalous pancreaticobiliary junction: image analysis and treatment principles

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Hepatobiliary & Pancreatic Diseases International 2004年第1期3卷 136-139页

作者： Ze-Li Yu, Li-Jun Zhang, Jian-Zhu Fu, Jie Li, Qing-Yu Zhang and Fou-Lai Chen beijing, china Department of General Surgery, beijing tongren hospital, Capital University of Medical Sciences, beijing 100730, china Department of General Surgery Beijing Tongren Hospital Capital University of Medical Sciences Beijing 100730 China. zhlj1968@***

BACKGROUND: Anomalous pancreaticobiliary junction is often associated with biliary tract carcinoma and acute pan- creatitis. We assessed the value of image analysis in the diag- nosis of patients with anomalous pancreaticobiliary junction (APBJ) and the principles for the treatment of APBJ. METHODS: Sixty-four patients with APBJ were subjected to ultrasound imaging, endoscopic retrograde cholangio- pancreatography (ERCP) and magnetic resonance cholan- giopancreatography (MRCP) before surgery. The diagnos- tic accuracy of image analysis and their surgical outcomes were evaluated retrospectively. RESULTS: On ERCP and MRCP, the length of the com- mon channel was calculated to be 15 mm or longer in all patients, and the angle of the junction was more than 75° in 49 (76.6%) of the 64 patients. Of the 64 patients, 28 were defined of pancreatic duct type (P-C) (28/64, 43.75%), 32 bile duct type (C-P) (32/64, 50%), and 4 common chan- nel type (4/64, 6.25%). CONCLUSIONS: Patients with APBJ are often associated with biliary tract and pancreatic diseases, and early detec- tion and correct surgical treatment could avoid serious complications. ERCP and MRCP are accurate in the diag- nosis of APBJ.

关键词： anomalous pancreaticobiliary junction image examination surgical treatment

Prognostic value of calcium and phosphorus status in elderly heart disease patients with tricuspid regurgitation

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Chinese Medical Journal 2024年第5期137卷 613-615页

作者： Qingrong Liu Kai Cao Ziang Li Yunqing Ye Qian Zhang Hongliang Zhang Haiyan Xu Zhe Li Yongjian Wu china-DVD Collaborators Department of Cardiology Beijing Aerospace General HospitalBeijing 100076China Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseaseChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100037China Department of beijing Institute of Ophthalmology Beijing Tongren HospitalCapital Medical UniversityBeijing 100000China 不详

To the Editor:Tricuspid regurgitation(TR)associated with valve disease is a general medical issue with growing prevalence and socioeconomic ***,especially moderate or severe TR,has been reported to be associated with an increased risk of heart failure and mortality.^([1])Studies have shown that blood calcium levels and blood phosphorus levels have a great influence on the human body,especially on the cardiovascular *** serum calcium levels were reported to be a risk factor for cardiovascular disease.^([2])A meta-analysis reported that moderate dietary calcium intake protects against cardiovascular and all-cause mortality and that calcium supplementation reduces mortality in women.^([3])

关键词： mortality regurgitation cardiovascular

Virtual Temporal Bone Anatomy

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Journal of Otology 2007年第1期2卷 56-59页

作者： XIA Yin, LI Xi-ping, HAN De-min, Department of Otorhinolaryngology, beijing tongren hospital, Capital Medical University, beijing, china, 100730 ZHOU Guo-hong, ZHAO Yuan-yuan Biomedical Academy of Capital Medical University Department of Otorhinolaryngology Beijing Tongren Hospital Capital Medical University Beijing China 100730 Biomedical Academy of Capital Medical University

Background The Visible Human Project(VHP) initiated by the U.S. National Library of Medicine has drawn much attention and interests from around the world. The Visible Chinese Human(VCH) project has started in china. The current study aims at acquiring a feasible virtual methodology for reconstructing the temporal bone of the Chinese population, which may provide an accurate 3-D model of important temporal bone structures that can be used in teaching and patient care for medical scientists and clinicians. Methods A series of sectional images of the temporal bone were generated from section slices of a female cadaver head. On each sectional image, SOIs (structures of interest) were segmented by carefully defining their contours and filling their areas with certain gray scale values. The processed volume data were then inducted into the 3D Slicer software(developed by the Surgical Planning Lab at Brigham and Women’s hospital and the MIT AI Lab) for resegmentation and generation of a set of tagged images of the SOIs. 3D surface models of SOIs were then reconstructed from these images. Results The temporal bone and structures in the temporal bone, including the tympanic cavity, mastoid cells, sigmoid sinus and internal carotid artery, were successfully reconstructed. The orientation of and spatial relationship among these structures were easily visualized in the reconstructed surface models. Conclusion The 3D Slicer software can be used for 3- dimensional visualization of anatomic structures in the temporal bone, which will greatly facilitate the advance of knowledge and techniques critical for studying and treating disorders involving the temporal bone.

关键词： 3-D reconstruction temporal bone Chinese Virtual Human