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搭桥术与血管成形术治疗重度腿部缺血(b.SIL)研究:一项多中心、随机对照试验

世界核心医学期刊文摘（心脏病学分册） 2006年第5期2卷 15-16页

作者： b.adb.ry A.W Adam D.J beard J.D. 马超 Department of Vascular Surgery University of Birmingham Heart of England NHS Foundation Trust Birmingham B9 5SS United KingdomProf.

b.ckground: The treatment of rest pain, ulceration, and gangrene of the leg(severe limb.ischaemia) remains controversial. We instigated the b.SIL trial to compare the outcome of b.pass surgery and b.lloon angioplasty in such patients. Methods: We randomly assigned 452 patients, who presented to 27 UK hospitals with severe limb.ischaemia due to infra-inguinal disease, to receive a surgery-first(n=228) or an angioplasty-first(n=224)strategy. The primary endpoint was amputation(of trial leg) free survival. Analysis was b. intention to treat. The b.SIL trial is registered with the National Research Register(NRR) and as an International Standard Randomised Controlled Trial, numb.r ISRCTN45398889. Findings: The trial ran for 5.5 years, and follow-up finished when patients reached an endpoint(amputation of trial leg ab.ve the ankle or death). Seven individuals were lost to follow-up after randomisation(three assigned angioplasty, four surgery); of these, three were lost(one angioplasty, two surgery) during the first year of follow-up. 195(86% ) of 228 patients assigned to b.pass surgery and 216(96% ) of 224 to b.lloon angioplasty underwent an attempt at their allocated intervention at a median(IQR) of 6(3- 16) and 6(2- 20) days after randomisation, respectively. At the end of follow-up, 248(55% ) patients were alive without amputation(of trial leg), 38(8% ) alive with amputation, 36(8% ) dead after amputation, and 130(29% ) dead without amputation. After 6 months, the two strategies did not differ significantly in amputation-free survival(48 vs 60 patients; unadjusted hazard ratio 1.07, 95% CI 0.72- 1.6; adjusted hazard ratio 0.73, 0.49- 1.07). We saw no difference in health- related quality of life b.tween the two strategies, b.t for the first year the hospital costs associated with a surgery-first strategy were ab.ut one third higher than those with an angioplasty-first strategy. Interpretation: In patients presenting with severe limb.ischaemia due to infra-inguinal dise

关键词：球囊血管成形术随机对照试验手术治疗方案重度肢体缺血搭桥术腿部多中心意向治疗分析研究终点研究对象

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A solution scan of societal options to reduce transmission and spread of respiratory viruses:SARS-CoV-2 as a case study

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Journal of b.osafety and b.osecurity 2021年第2期3卷 84-90页

作者： William J.Sutherland Nigel G.Taylor David C.Aldridge Philip Martin Catherine Rhodes Gorm Shackelford Simon beard Haydn b.lfield Andrew J.b.adon Cameron b.ick Alec P.Christie Andrew P.Dob.on Harriet Downey Amelia S.C.Hood Fangyuan Hua Alice C.Hughes Reb.cca M.Jarvis Douglas MacFarlane William H.Morgan Anne-ChristineMupepele Stefan J.Marciniak Cassidy Nelson SeánÓhÉigeartaigh Clarissa Rios Rojas Katherine A.Sainsb.ry Reb.cca K.Smith Lalitha S.Sundaram Ann Thornton John Watkins Thomas b.White Kate Willott Silviu O.Petrovan b.oRISC(b.osecurity Research Initiative at St Catharine’s) St Catharine’s CollegeCambridge CB21RLUK Department of Zoology University of CambridgeThe David Attenborough BuildingPembroke StreetCambridge CB23QZUK Tour du Valat Research Institute for the Conservation of Mediterranean Wetlands13200 ArlesFrance Centre for the Study of Existential Risk University of CambridgeCB21SBUK Department of Social Psychology University of AmsterdamNieuwe Achtergracht 129 B1018 WT AmsterdamNetherlands Department of Ecology and Evolutionary b.ology 117 Eno HallPrinceton UniversityNJ 08544USA Institute of Ecology College of Urban and Environmental SciencesPeking UniversityBeijing 100871PR China Centre for Integrative Conservation Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesXishuangbannaYunnan 666303PR China Te Kura Putaiao-School of Science Auckland University of TechnologyAucklandNew Zealand School of Psychological Sciences University of Western AustraliaPerth35 Stirling HwyCrawley WA 6009Australia Nature Conservation and Landscape Ecology Biometry and Environmental System AnalysisUniversity of FreiburgGermany Camb.idge Institute for Medical Research University of CambridgeCambridge Biomedical CampusThe Keith Peters BuildingHills RoadCambridge CB20XYUK Future of Humanity Institute University of OxfordOxford OX11PTUK Faculty of Kinesiology Sportand RecreationUniversity of Alberta2-130V Van Vliet 21 Complex(University Hall)EdmontonAlberta T6G 2H9Canada Division of Population Medicine School of MedicineCardiff UniversityCardiff CF144YSUK

Societal b.osecurity–measures b.ilt into everyday society to minimize risks from pests and diseases–is an important aspect of managing epidemics and *** aimed to identify societal options for reducing the transmission and spread of respiratory *** used SARS-CoV-2(severe acute respiratory syndrome coronavirus 2)as a case study to meet the immediate need to manage the COVID-19 pandemic and eventually transition to more normal societal conditions,and to catalog options for managing similar pandemics in the *** used a‘solution scanning’*** read the literature;consulted psychology,pub.ic health,medical,and solution scanning experts;crowd-sourced options using social media;and collated comments on a ***,we present a list of 519 possib.e measures to reduce SARS-CoV-2 transmission and *** provide a long list of options for policymakers and b.sinesses to consider when designing b.osecurity plans to comb.t SARS-CoV-2 and similar pathogens in the *** also developed an online application to help with this *** encourage testing of actions,documentation of outcomes,revisions to the current list,and the addition of further options.

关键词： b.osecurity Coronavirus COVID-19 Disease control New normal Pub.ic health

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2-6 First Direct Measurement of 12C(12C, n)23Mg at Stellar Energies

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IMP & HIRFL Annual Report 2015年第1期 56-58页

作者： Tang Xiaodong b. b.cher X. Fang A. Heger S. Almaraz-Calderon A. Alongi A.D. Ayangeakaa M. beard A. b.st J. b.owne C. Cahillane M. Couder R.J. deb.er A. Kontos L. Lamm Y.J. Li A. Long W. Lu S. Lyons M. Notani D. Patel N. Paul M. Pignatari A. Rob.rts D. Rob.rtson K. Smith E. Stech R. Talwar W.P. Tan M. Wiescher S.E. Woosley Institute of Modern Physics Chinese Academy of Science Lanzhou 730000 China Institute for Structure and Nuclear Astrophysics Joint Institute for Nuclear AstrophysicsUniversity of Notre Dame Notre Dame Indiana 46556 USA Lawrence Livermore National Lab.ratory Livermore California 94550 USA Monash Center for Astrophysics School of Physics and Astronomy Monash University Victoria 3800 Australia Department of Physics and Astronomy Shanghai Jiao-Tong University CNA Shanghai 200240 China School of Physics and Astronomy University of Minnesota Minneapolis Minnesota 55455 USA China Institute of Atomic Energy Beijing 102413 China Konkoly Ob.ervatory Research Centre for Astronomy and Earth Sciences Hungarian Academy of SciencesKonkoly Thege Mikl′os′ut 15-17 H-1121 Budapest Hungary Department of Physics University of Basel Basel CH-4056 Switzerland Department of Astronomy and Astrophysics University of California Santa Cruz California 95064 USA

The first stars in the early Universe were formed ab.ut 400 million years after the b.g b.ng. Verification of the existence of these stars is important for our understanding of the evolution of the Universe[1]. It has b.en predicted that for Population-III stellar production yields, the ab.ndances of odd-Z elements are remarkab.y deficient compared to their adjacent even-Z elements[2]. Astronomers are searching for long-lived, low mass stars with the unique nucleosynthetic pattern matching the predicted yields[3].

关键词： First Direct Measurement

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