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Processes of initial collision and suturing between India and Asia

Science China Earth Sciences 2017年第4期60卷 635-651页

作者： DING Lin Satybaev MAKSATBEK CAI FuLong WANG HouQi SONG PeiPing JI WeiQiang XU Qiang ZHANG LiYun Qasim MUHAMMAD baral upendra Key Laboratory of Continental Collision and Plateau Uplift Institute of Tibetan Plateau Researchand Center for Excellence in Tibetan Plateau Earth SciencesChinese Academy of SciencesBeijing 100101China University of the Chinese Academy of Sciences Beijing 100049China Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China

The initial collision between Indian and Asian continents marked the starting point for transformation of land-sea thermal contrast,uplift of the Tibet-Himalaya orogen,and climate change in *** this paper,we review the published literatures from the past 30 years in order to draw consensus on the processes of initial collision and suturing that took place between the Indian and Asian *** a comparison of the different methods that have been used to constrain the initial timing of collision,we propose that the tectono-sedimentary response in the peripheral foreland basin provides the most sensitive index of this event,and that paleomagnetism presents independent evidence as an alternative,reliable,and quantitative research *** contrast to previous studies that have suggested collision between India and Asia started in Pakistan between ca.55 Ma and50 Ma and progressively closed eastwards,more recent researches have indicated that this major event first occurred in the center of the Yarlung Tsangpo suture zone(YTSZ) between ca.65 Ma and 63 Ma and then spreading both eastwards and *** continental collision is a complicated process,including the processes of deformation,sedimentation,metamorphism,and magmatism,different researchers have tended to define the nature of this event based on their own understanding,an intuitive bias that has meant that its initial timing has remained controversial for ***,we recommend the use of reconstructions of each geological event within the orogenic evolution sequence as this will allow interpretation of collision timing on the basis of multidisciplinary methods.

关键词： Timing of initial collision between the Indian and Asian continents Collision criteria Transform fault Subduction zone Magmatism Deformation

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印度与欧亚大陆初始碰撞时限、封闭方式和过程

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中国科学：地球科学 2017年第3期47卷 293-309页

作者：丁林 Satybaev MAKSATBEK 蔡福龙王厚起宋培平纪伟强许强张利云 Qasim MUHAMMAD baral upendra 中国科学院青藏高原研究所大陆碰撞与高原隆升重点实验室中国科学院青藏高原地球科学卓越创新中心北京100101 中国科学院大学北京100049 中国科学院地质与地球物理研究所北京100029

印度与欧亚大陆初始碰撞是海陆热力对比变化、青藏高原-喜马拉雅造山带形成和亚洲气候转变的起点.本文根据近30年国内外的研究进展,系统总结了大陆初始碰撞的研究历史.对比了十多种初始碰撞研究方法,我们认为周缘前陆盆地的构造-沉积响... 详细信息

印度与欧亚大陆初始碰撞是海陆热力对比变化、青藏高原-喜马拉雅造山带形成和亚洲气候转变的起点.本文根据近30年国内外的研究进展,系统总结了大陆初始碰撞的研究历史.对比了十多种初始碰撞研究方法,我们认为周缘前陆盆地的构造-沉积响应对大陆初始碰撞最为敏感,而古地磁学作为独立的证据也是非常好的定量研究方法.关于碰撞过程,与西方传统观点认为55~50Ma碰撞首先发生在西部衔接点,随后向东闭合的模式不同;最新的研究结果表明,印度与欧亚大陆首先于雅鲁藏布江缝合带中部发生正向碰撞,时间为65~63Ma,随后向东西两侧穿时性碰撞.大陆碰撞是一个复杂的造山过程,涉及构造、沉积、变质和岩浆作用等多个方面,不同学科的学者通常喜欢从各自学科的角度来定义碰撞.我们建议使用多学科结合、相互验证的方法,避免以偏概全、以点带面的现象发生,尽量将每个阶段发生的事件真实地还原到碰撞造山演化的时间序列中.

关键词：青藏高原印度板块欧亚板块初始碰撞封闭过程

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Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

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Genes & Diseases 2024年第1期11卷 34-37页

作者： Budhadev baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay Kumar Jain Debi Chatterji Vinod Kumar Amit Mishra Awanish Kumar Hem Chandra Jha Infection Bioengineering Group Department of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research Center IndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials Science Indian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&Bioengineering Indian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of Biotechnology National Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India

Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(GC).*** is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关键词： H.pylori pylori Helicobacter

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Assessing intersectional gender analysis in Nepal’s health management information system: a case study on tuberculosis for inclusive health systems

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贫困所致传染病(英文) 2024年第2期13卷 52-62页

作者： Parajuli Ayuska Kakchapati Sampurna Arjyal Abriti Joshi Deepak Kharel Chandani del Barrio Mariam Otmani baral Sushil C HERD International Saibu Awas Cr-Marga Bhaisepati Lalitpur Nepal UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) World Health Organization Geneva Switzerland

Background Tuberculosis (TB) remains a major public health problem in Nepal, high in settings marked by prevalent gender and social inequities. Various social stratifiers intersect, either privileging or oppressing individuals based on their characteristics and contexts, thereby increasing risks, vulnerabilities and marganilisation associated with TB. This study aimed to assess the inclusiveness of gender and other social stratifiers in key health related national policies and the Health Management Information System (HMIS) of National Tuberculosis Programme (NTP) by conducting an intersectional analysis of TB cases recorded via *** A desk review of key policies and the NTP’s HMIS was conducted. Retrospective intersectional analysis utilized two secondary data sources: annual NTP report (2017–2021) and records of 628 TB cases via HMIS 6.5 from two TB centres (2017/18–2018/19). Chi-square test and multi-variate analysis was used to assess the association between social stratifers and types of TB, registration category and treatment *** Gender, social inclusion and concept of intersectionality are incorporated into various health policies and strategies but lack effective implementation. NTP has initiated the collection of age, sex, ethnicity and location data since 2014/15 through the HMIS. However, only age and sex disaggregated data are routinely reported, leaving recorded social stratifiers of TB patients static without analysis and dissemination. Furthermore, findings from the intersectional analysis using TB secondary data, showed that male more than 25 years exhibited higher odds [adjusted odds ratio (aOR) = 4.95, 95% confidence interval (CI): 1.60–19.06,P = 0.01)] of successful outcome compared to male TB patients less than 25 years. Similarly, sex was significantly associated with types of TB (P < 0.05) whereas both age (P < 0.05) and sex (P < 0.05) were significantly associated with patient registration category (old/new cases).Conclusio

关键词： Tuberculosis Intersectional gender analysis Gender and social inequities Social determinant Health Management Information System National Tuberculosis Programme Social inclusion Gender

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GPSM2在肿瘤中的研究进展

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国际外科学杂志 2024年第9期51卷 640-644,F0004页

作者：史友权 Shantanu baral 程一帆孙倩男汪刘华张跃王道荣大连医科大学扬州临床医学院扬州225000 扬州大学临床医学院扬州225000 南京大学医学院教学医院苏北人民医院扬州225000 苏北人民医院扬州225000 徐州市肿瘤医院胃肠外科徐州221000

G蛋白信号调节因子2(GPSM2)属于GPSM家族的一员,GPSM2在查德利-麦卡洛综合征、类风湿性关节、系统性红斑狼疮等疾病的发生发展中起着重要作用,并参与非小细胞肺癌、乳腺癌、肝癌、胰腺癌、浆液性卵巢癌、尤文肉瘤和骨肉瘤等肿瘤的增殖... 详细信息

G蛋白信号调节因子2(GPSM2)属于GPSM家族的一员,GPSM2在查德利-麦卡洛综合征、类风湿性关节、系统性红斑狼疮等疾病的发生发展中起着重要作用,并参与非小细胞肺癌、乳腺癌、肝癌、胰腺癌、浆液性卵巢癌、尤文肉瘤和骨肉瘤等肿瘤的增殖、侵袭和转移。目前暂无GPSM2在肿瘤进展机制方面的相关综述。本文将总结了近年来关于GPSM2在肿瘤中的研究进展,重点关注其作用及机制,以期为进一步的研究提供参考和指导。

关键词：基因肿瘤预后研究综述

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Modelling and analysis of decentralized energy systems with photovoltaic, micro-hydro, battery and diesel technology for remote areas of Nepal

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Clean Energy 2021年第4期5卷 690-703页

作者： Nawaraj Sanjel Bivek baral Department of Mechanical Engineering Kathmandu UniversityDhulikhelNepal

Remote areas of Nepal suffer from limited or no access to *** electricity access in remote areas is one of the foremost challenges of any developing *** purpose of this study is to develop and propose a reliable and low-cost model for *** study presents an optimized choice between decentralized renewable-energy systems and grid *** for an analytical method for the modelling and analysis of electrification options based on life-cycle cost(LCC)and economic distance limit,each energy system for varied load conditions is compared for a better option.A framework for energy-system selection based on available resources is *** compares the grid-expansion option with potential isolated renewable-energy systems to ensure energy access to the area under ***,off-grid configurations that rely on renewable energy sources are also considered for the necessity of backup supply to ensure continuous power to the research ***-economic assessment is carried out for different off-grid and hybrid configurations proposed in this study and their feasibility checks are carefully *** efficacy of the proposed hybrid energy systems is assessed by comparing the life cycle and energy cost and by performing different additional sensitivity *** study concludes that reduced generation cost supports the increasing penetration of *** LCC for grid expansion is the most economical under high-load conditions,whereas for the isolated and sparsely settled populations with low-load conditions,photovoltaic power backed up with a diesel generator is the most economical.

关键词： decentralized energy system energy planning rural electrification economic distance limit life-cycle cost

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Performance of marine clay stabilised with vacuum pressure: Based on Queensland experience

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Journal of Rock Mechanics and Geotechnical Engineering 2019年第3期11卷 598-611页

作者： Buddhima Indraratna Cholachat Rujikiatkamjorn Pankaj baral Jayantha Ameratunga Industrial Transformation Training Centre(ITTC)for Advanced Technologies in Rail Track Infrastructure&Centre for Geomechanics and Railway Engineering(CGRE) School of CivilMining and Environmental EngineeringUniversity of WollongongWollongong CityNSW 2522Australia School of Civil Mining and Environmental EngineeringUniversity of WollongongWollongong CityNSW 2522Australia Centre for Geomechanics and Railway Engineering University of WollongongWollongong CityNSW 2522Australia Golder Associates Pty Ltd. MiltonQueensland 4064Australia

Stabilising soft marine clay and estuarine soils via vacuum preloading has become very popular in Australasia over the past decades because it is a cost-effective and time-efficient *** recent times,new land on areas outside but adjacent to existing port amenities,the Fisherman Islands at the Port of Brisbane(POB),was reclaimed to cater for an increase in trade activities.A vacuum preloading method combined with surcharge to stabilise the deep layers of soil was used to enhance the application of prefabricated vertical drains(PVDs).This paper describes the performance of this combined surcharge fill and vacuum system under the embankment and also compares it with a surcharge loading system to demonstrate the benefits of vacuum pressure over conventional *** performance of this embankment is also presented in terms of field monitoring data,and the relative performance of the vacuum together with non-vacuum systems is *** analytical solution to radial consolidation with time-dependent surcharge loading and vacuum pressure is also presented in order to predict the settlement and associated excess pore water pressure(EPWP)of deposits of thick soft clay.

关键词： Soft clay Prefabricated vertical drains(PVDs) Vacuum consolidation Membrane-less system Membrane system

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Estimation of de-trapped charge for diagnosis of transformer insulation using short-duration polarisation current employing detrended fluctuation analysis

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High Voltage 2020年第5期5卷 636-641页

作者： Saurabh Dutta Deepak Mishra Arijit baral Sivaji Chakravorti Department of Electrical Engineering Indian Institute of Technology(ISM)DhanbadIndia Department of Electrical Engineering Jadavpur UniversityKolkataIndia

Researchers have shown that the value of charge carriers,de-trapped from the oil-paper interface of power transformer insulation,is useful in carrying out the ***,the evaluation of the de-trapped charge requires the analysis of polarisation-depolarisation *** an off-line time-consuming process,the measurement and analysis of polarisation and depolarisation current(PDC)data are not practically *** study presents a detrended fluctuation analysis-based technique to estimate the magnitude of normalised de-trapped charge using the polarisation current measured for a short *** the proposed technique,the requirement of measuring the complete PDC data,for diagnosis purposes,can be ***,the technique also eliminates the requirement of depolarisation current which in turn facilitates a reduction in equipment shutdown *** applicability of the proposed technique is tested on the data obtained from several real-life power transformers.

关键词： charge insulation diagnosis

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Radial consolidation characteristics of soft undisturbed clay based on large specimens

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第6期10卷 1037-1045页

作者： Pankaj baral Cholachat Rujikiatkamjorn Buddhima Indraratna Richard Kelly Research Centre for Geomechanics and Railway Engineering Faculty of Engineering and Information SciencesUniversity of WollongongWollongongNSW2522Australia SMEC-Australia and New Zealand Division BrisbaneQueenslandAustralia

In recent years, reconstituted small samples have often been used to assess the performance of radial consolidation due to prefabricated vertical drains(PVDs), but the permeability and compressibility of samples of undisturbed soil often differ from those of the remoulded ones. The problem seems more complex in marine environment due to the presence of random coarse particles including gravels, shells and natural partings. Performing small-scale laboratory experiment with reconstituted samples, especially in marine environment, cannot predict the exact soil behaviour in the field. This paper describes an experimental programme that measures radial consolidation using a conventional Rowe cell and a largescale consolidometer, where the samples of undisturbed soil obtained from a site along the Pacific Highway(north of Sydney) were compared using measured settlements and excess pore ***, this paper highlights the implications of the smear effect and sample size influence, which are imperative in translating the laboratory testing practices to actual real-life behaviour. The effect of vacuum pressure on the coefficient of radial consolidation of a large-scale undisturbed test specimen is also discussed. The paper demonstrates that the extent of smear zone in the field can be very similar to the large-scale laboratory consolidation test using a scaled-down drain and mandrel, but considerably different from the data obtained for small laboratory specimens.

关键词： Consolidation Soft soil Vertical drain Undisturbed clay

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Activation of microbial secondary metabolic pathways:Avenues and challenges

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Synthetic and Systems Biotechnology 2018年第3期3卷 163-178页

作者： Bikash baral Amir Akhgari Mikko Metsä-Ketelä Department of Biochemistry University of TurkuFIN-20014TurkuFinland

Microbial natural products are a tremendous source of new bioactive chemical entities for drug *** generation sequencing has revealed an unprecedented genomic potential for production of secondary metabolites by diverse micro-organisms found in the environment and in the *** mining has further led to the discovery of numerous uncharacterized‘cryptic’metabolic pathways in the classical producers of natural products such as Actinobacteria and *** biosynthetic gene clusters may code for improved biologically active metabolites,but harnessing the full genetic potential has been hindered by the observation that many of the pathways are‘silent’under laboratory *** we provide an overview of the various biotechnological methodologies,which can be divided to pleiotropic,biosynthetic gene cluster specific,and targeted genome-wide approaches that have been developed for the awakening of microbial secondary metabolic pathways.

关键词： Biosynthesis Chemical diversity Genome mining Metabolic engineering Synthetic biology

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