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High Voltage 2022年第1期7卷 52-63页

作者： Yu Gao Jing Li bangbang xu Binyuan Ye Boxue Du School of Electrical and Information Engineering Tianjin UniversityTianjinChina Research Institute for Materials Science and Technology Waseda UniversityTokyoJapan State Grid Shandong Electric Power Company Overhauling Company JinanChina

Chemical corrosion and gamma‐ray irradiation appeared with the loss of coolant accident may seriously threaten the safe operation of a nuclear power plant,where epoxy resin(ER)‐based materials are widely *** is urgent to study the effects of the corrosion and the irradiation on the electrical performance in an ER‐based *** this work,ER/Al_(2)O_(3)nanocomposite samples with 0,1,3,5‐wt%nano Al2O3 filler content were prepared at the thickness of 2 mm,and the total gamma irradiation dose was 0,500,and 1000 *** samples were chemically corroded in a boric acid solution(pH=4.7)and a trisodium phosphate alkaline solution(pH=11)at 60℃and 100℃for 48 *** transport behaviour in the samples was derived from the surface potential decay *** addition,the sample structures were characterised to analyse the corrosion mechanism in the *** results indicated that the depth and the density of the trap showed a temperature‐dependent manner associated with the *** the addition of appropriate content of the filler,the trap centre was deepened and the carrier mobility was limited even after the *** is found that the appearance of hydroxyl and carboxyl groups during corrosion,the interaction between the nanoparticle and the matrix and the crosslinking reaction caused by the irradiation are responsible for the variation in charge transport behaviour.

关键词： corrosion transport behaviour

通脉舒筋针法联合痛消合剂外敷治疗腰椎术后残余腰背痛临床研究

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新中医 2023年第18期55卷 139-144页

作者：徐棒棒开封市人民医院河南开封475000

目的:观察通脉舒筋针法联合痛消合剂外敷治疗腰椎术后残余腰背痛的临床疗效。方法:选取96例行腰椎间融合术治疗且术后3个月仍有腰背痛的患者,按照随机数字表法分为对照组和观察组各48例。对照组给予塞来昔布胶囊治疗,观察组给予通脉舒... 详细信息

目的:观察通脉舒筋针法联合痛消合剂外敷治疗腰椎术后残余腰背痛的临床疗效。方法:选取96例行腰椎间融合术治疗且术后3个月仍有腰背痛的患者,按照随机数字表法分为对照组和观察组各48例。对照组给予塞来昔布胶囊治疗,观察组给予通脉舒筋针法联合痛消合剂外敷治疗。2组均治疗2周,随访3个月。比较2组临床疗效,Oswestry功能障碍指数(ODI)、视觉模拟评分法(VAS)评分,疼痛因子[神经肽Y (NPY)、P物质(SP)、前列腺素E2 (PGE2)]、氧化应激状态指标[超氧化物歧化酶(SOD)、总抗氧化能力(T-AOC)、丙二醛(MDA)]水平,以及复发率,记录2组不良反应。结果:治疗后,观察组临床疗效总有效率91.11%,高于对照组75.00%(P0.05)。结论:通脉舒筋针法联合痛消合剂外敷有利于减轻腰椎术后残余腰背痛,改善腰椎功能,安全性好,复发率低。

关键词：腰椎间融合术后腰背痛通脉舒筋针法痛消合剂外敷腰椎功能氧化应激复发

聚合物绝缘材料载流子陷阱的表征方法及陷阱对绝缘击穿影响的研究进展

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高电压技术 2019年第7期45卷 2219-2230页

作者：高宇王小芳李楠许棒棒王继隆杜伯学天津大学电气自动化与信息工程学院

聚合物绝缘材料在电气设备中已得到广泛应用,其绝缘安全对电气设备的可靠服役具有显著影响。由于聚合物材料内部因生产工艺、运行老化等原因形成大量的载流子陷阱,为空间电荷的积聚提供了条件,从而使聚合物绝缘材料面临着击穿破坏的风险... 详细信息

聚合物绝缘材料在电气设备中已得到广泛应用,其绝缘安全对电气设备的可靠服役具有显著影响。由于聚合物材料内部因生产工艺、运行老化等原因形成大量的载流子陷阱,为空间电荷的积聚提供了条件,从而使聚合物绝缘材料面临着击穿破坏的风险,严重威胁其运行安全。因此,对聚合物绝缘材料内部的载流子陷阱进行有效表征,探寻其与材料老化、击穿的相关性,对于保障绝缘材料安全具有重要意义。针对聚合物绝缘材料载流子陷阱表征方法的研究进展进行总结,分析并评述了各类材料陷阱表征方法的基本原理、应用及局限性。研究表明:等温表面电位衰减法、热刺激电流法、光刺激放电法和电声脉冲法均可有效进行载流子陷阱的表征,但需进一步建立精细化数学模型以适用于不同尺寸规格的样品,并探究多种表征方法的内在关联性,发展聚合物材料载流子陷阱的三维成像技术。通过各类物理、化学手段实施聚合物材料的陷阱调控或陷阱编缉,可为提高材料的绝缘性能提供了新的思路。

关键词：聚合物绝缘材料载流子陷阱表征表面电位衰减热刺激电流光刺激放电电声脉冲法

关节镜下清理术联合胫骨近端高位截骨术治疗老年膝关节炎疗效分析

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中国烧伤创疡杂志 2024年第1期36卷 49-52页

作者：武文凯徐棒棒武科开封市人民医院骨外科河南开封475000

目的分析探讨关节镜下清理术联合胫骨近端高位截骨术治疗老年膝关节炎的临床疗效。方法选取2020年4月至2022年4月开封市人民医院收治的94例老年膝关节炎患者作为研究对象,按照不同治疗方法将其分为观察组(47例)和对照组(47例),观察组患... 详细信息

目的分析探讨关节镜下清理术联合胫骨近端高位截骨术治疗老年膝关节炎的临床疗效。方法选取2020年4月至2022年4月开封市人民医院收治的94例老年膝关节炎患者作为研究对象,按照不同治疗方法将其分为观察组(47例)和对照组(47例),观察组患者采用关节镜下清理术联合胫骨近端高位截骨术治疗,对照组患者单纯采用关节镜下清理术治疗,对比观察两组患者住院时间、疼痛程度、膝关节功能及生活质量。结果观察组患者住院时间明显长于对照组(t=4451,P<0001);术后6个月,观察组患者视觉模拟评分法(VAS)评分明显低于对照组、Lysholm评分明显高于对照组(t=11199、10774,P均<0001);术后6个月,观察组患者健康调查量表36(SF-36)各维度评分均明显高于对照组(t=3330、3527、3350、3682、3633、3514、3473、3410,P均=0001)。结论与单纯行关节镜下清理术相比,关节镜下清理术联合胫骨近端高位截骨术虽会延长老年膝关节炎患者住院时间,但却能明显减轻远期疼痛程度,加速膝关节功能恢复,提高患者生活质量,临床应用价值较高。

关键词：老年膝关节炎关节镜下清理胫骨近端高位截骨疼痛膝关节功能生活质量

续断接骨汤对股骨颈骨折患者髋关节置换术后康复的影响

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河南医学研究 2021年第33期30卷 6270-6272页

作者：王福光唐虎子吕立桃徐棒棒开封市人民医院骨科河南开封475000

目的探讨续断接骨汤对股骨颈骨折患者髋关节置换术(HR)术后康复的影响。方法选取2017年3月至2019年1月开封市人民医院82例股骨颈骨折患者作为研究对象,按照随机数表法将患者分为对照组和观察组,各41例。给予两组患者HR治疗,术后对照组... 详细信息

目的探讨续断接骨汤对股骨颈骨折患者髋关节置换术(HR)术后康复的影响。方法选取2017年3月至2019年1月开封市人民医院82例股骨颈骨折患者作为研究对象,按照随机数表法将患者分为对照组和观察组,各41例。给予两组患者HR治疗,术后对照组接受常规方法治疗,观察组接受续断接骨汤治疗。观察对比两组症状缓解情况、治疗前后血清骨代谢生化指标[骨碱性磷酸酶(BALP)、尿脱氧吡啶酚(DPD)、抗酒石酸酸性磷酸酶5b(TRACP5b)]、骨细胞因子[骨形态发生蛋白(BMP)、成纤维细胞生长因子(FGF)、转化生长因子-β(TGF-β)]、并发症发生率、髋关节功能(Harris)评分。结果观察组疼痛、肿胀消退时间短于对照组(P<0.05);观察组治疗后BALP水平高于对照组,DPD、TRACP5b水平低于对照组(P<0.05);观察组治疗后BMP、FGF、TGF-β水平高于对照组(P<0.05);观察组术后并发症发生率(4.88%)低于对照组(21.95%)(P<0.05);观察组治疗后6、12个月Harris评分高于对照组(P<0.05)。结论股骨颈骨折患者HR后采用续断接骨汤治疗,可调节血清骨代谢生化指标、骨细胞因子水平,减轻疼痛、肿胀,减少术后并发症发生,改善髋关节功能。

关键词：股骨颈骨折续断接骨汤髋关节置换术骨代谢

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis

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Neural Regeneration Research 2025年第2期20卷 354-365页

作者： Li xu Huiming xu Changyong Tang Department of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor *** date,no effective treatment exists as the exact causative mechanism remains ***,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic *** most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets *** experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum *** this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model *** addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.

关键词： aquaporin-4 experimental model neuromyelitis optica spectrum disorder pathogenesis

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GA3浸种对玉米种子发芽及生理性状的影响

种子 2020年第6期39卷 37-42页

作者：王改净陈亚龙赵明君徐棒棒程紫钦高青蕊韩赞平河南科技大学农学院河南洛阳471003

为了探讨赤霉素(GA3)对玉米种子发芽及生理性状的影响,以普通玉米自交系豫537 A为材料,采用不同浓度(0、100、200、300、400 mg·L^-1)和时间(0、4、6、8 h)的赤霉素(GA3)进行种子处理,按照GB/T 5520-2011进行标准发芽试验,研究其发芽... 详细信息

为了探讨赤霉素(GA3)对玉米种子发芽及生理性状的影响,以普通玉米自交系豫537 A为材料,采用不同浓度(0、100、200、300、400 mg·L^-1)和时间(0、4、6、8 h)的赤霉素(GA3)进行种子处理,按照GB/T 5520-2011进行标准发芽试验,研究其发芽势、发芽率、发芽指数、活力指数等发芽性状,测定可溶性糖(SS)、丙二醛(MDA)、α-淀粉酶、β-淀粉酶等生理性状。结果表明:1)GA3处理时间为8 h,浓度为100 mg·L^-1时,发芽势最高,极显著高于其余各水平组合和对照(ck);GA 3处理时间和浓度分别为8 h-200 mg·L^-1、6 h-100 mg·L^-1、6 h-400 mg·L^-1时,发芽率显著高于对照(ck);GA 3处理时间为4 h,浓度为200 mg·L^-1时,发芽指数最高,显著高于对照(ck)。2)GA 3处理时间为4 h,浓度为400 mg·L^-1时,玉米幼苗最高,极显著高于其余各水平组合,显著高于对照(ck);GA 3处理时间为4 h,浓度为400 mg·L^-1时根长最长,极显著高于对照(ck);GA 3处理时间和浓度分别为4 h-400 mg·L^-1、8 h-200 mg·L^-1、6 h-200 mg·L^-1、6 h-300 mg·L^-1、6 h-400 mg·L^-1时植株干重极显著或显著高于对照(ck);GA 3处理时间为8 h,浓度为100 mg·L^-1时,根冠比最高,极显著高于其余各水平组合和对照(ck)。3)GA 3浓度为300 mg·L^-1,处理时间为4 h时可溶性糖含量最高;GA 3浓度为200 mg·L^-1,处理时间为4 h时,丙二醛含量最高;GA 3浓度为300 mg·L^-1,处理时间为4 h时,α-淀粉酶含量最高;GA 3浓度为100 mg·L^-1,处理时间为8 h时,β-淀粉酶含量最高。因此,GA 3浸种对玉米种子萌发及幼苗生长有促进作用,其效果受浸种浓度及浸种时间2个因素影响。

关键词：玉米种子活力种子质量发芽率

Reducing the measurement errors in nonadiabatic holonomic quantum computers

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 64-70页

作者： Guo-Fu xu Department of Physics Shandong University

Nonadiabatic holonomic quantum computers serve as the physical platform for nonadiabatic holonomic quantum *** quantum computation has entered the noisy intermediate-scale era, building accurate intermediate-scale nonadiabatic holonomic quantum computers is clearly necessary. Given that measurements are the sole means of extracting information, they play an indispensable role in nonadiabatic holonomic quantum computers. Accordingly, developing methods to reduce measurement errors in nonadiabatic holonomic quantum computers is of great importance. However, while much attention has been given to the research on nonadiabatic holonomic gates, the research on reducing measurement errors in nonadiabatic holonomic quantum computers is severely lacking. In this study, we propose a measurement error reduction method tailored for intermediate-scale nonadiabatic holonomic quantum computers. The reason we say this is because our method can not only reduce the measurement errors in the computer but also be useful in mitigating errors originating from nonadiabatic holonomic gates. Given these features,our method significantly advances the construction of accurate intermediate-scale nonadiabatic holonomic quantum computers.

关键词： quantum holonomy quantum computation measurement errors

Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials

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Neural Regeneration Research 2025年第9期20卷 2437-2453页

作者： Siyi xu Junqiu Jia Rui Mao Xiang Cao Yun xu Department of Neurology Nanjing Drum Tower HospitalClinical College of Jiangsu UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalChinese Academy of Medical Science&Peking Union Medical CollegeNanjingJiangsu ProvinceChina Department of Neurology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology and Institute of Translational Medicine for Brain Critical Diseases Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory for Molecular Medicine Medical School of Nanjing UniversityNanjingJiangsu ProvinceChina Nanjing Neurology Medical Center NanjingJiangsu ProvinceChina

Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health *** optimal therapies and improving the long-term neurological functions of patients with acute central nervous system injuries are urgent *** are susceptible to damage after acute central nervous system injury,and this leads to the release of toxic levels of reactive oxygen species,which induce cell ***,a selective form of autophagy,is crucial in eliminating redundant or damaged mitochondria during these *** evidence has highlighted the significant role of mitophagy in acute central nervous system *** this review,we provide a comprehensive overview of the process,classification,and related mechanisms of *** also highlight the recent developments in research into the role of mitophagy in various acute central nervous system injuries and drug therapies that regulate *** the final section of this review,we emphasize the potential for treating these disorders by focusing on mitophagy and suggest future research paths in this area.

关键词： autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control mitophagy spinal cord injury subarachnoid hemorrhage traumatic brain injury

Enantio-divergent C–H borylation with two different ligands from a single chiral source

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Science China Chemistry 2025年第1期 226-232页

作者： Rongrong Du Senmiao xu State Key Laboratory for Oxo Synthesis and Selective Oxidation Lanzhou Institute of Chemical Physics Chinese Academy of Sciences College of Material Chemistry and Chemical Engineering Key Laboratory of Organosilicon Chemistry and Material TechnologyMinistry of Education Hangzhou Normal University University of Chinese Academy of Sciences

Reported here is an iridium-catalyzed enantio-divergent C（sp3）–H borylation of α-gem-dimethyl groups of trifluoromethyl ketone-derived hydrazones to construct a series of acyclic all-carbon quaternary stereocenters with a high level of chiral induction. Two different chiral bidentate boryl ligands from a common chiral source not only can switch the enantioselectivity but also are complementary in terms of the substrate scope.

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