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Radiation-induced inflammation and autoimmune diseases

Military Medical Research 2018年第1期5卷 62-71页

作者： Rasoul Yahyapour Peyman Amini Saeed Rezapour Mohsen Cheki Abolhasan Rezaeyan bagher farhood Dheyauldeen Shabeeb Ahmed Eleojo Musa Hengameh Fallah Masoud Najafi School of Medicine Jiroft University of Medical Sciences Department of Radiology Faculty of ParamedicalTehran University of Medical Sciences Department of Radiologic Technology Faculty of ParamedicineAhvaz Jundishapur University of Medical Sciences Department of Medical Physics School of MedicineIran University of Medical Sciences Departments of Medical Physics and Radiology Faculty of Paramedical SciencesKashan University of Medical Sciences Department of Medical Physics and Biomedical Engineering Faculty of MedicineTehran University of Medical Sciences (International Campus) Department of Physiology College of MedicineUniversity of Misan Research center for molecular and cellular imaging Tehran University of Medical Sciences Department of Chemistry Faculty of ScienceIslamic Azad University Radiology and Nuclear Medicine Department School of Paramedical Sciences Kermanshah University of Medical Science

Currently,ionizing radiation(IR)plays a key role in the agricultural and medical industry,while accidental exposure resulting from leakage of radioactive sources or radiological terrorism is a serious *** to IR has various detrimental effects on normal *** an increased risk of carcinogenesis is the best-known long-term consequence of IR,evidence has shown that other diseases,particularly diseases related to inflammation,are common disorders among irradiated *** disorders are among the various types of immune diseases that have been investigated among exposed *** diseases and diabetes are two autoimmune diseases potentially induced by ***,the precise mechanisms of IR-induced thyroid diseases and diabetes remain to be elucidated,and several studies have shown that chronic increased levels of inflammatory cytokines after exposure play a pivotal ***,cytokines,including interleukin-1(IL-1),tumor necrosis factor(TNF-α)and interferon gamma(IFN-α),play a key role in chronic oxidative damage following exposure to ***,these cytokines change the secretion of insulin and thyroid-stimulating hormone(TSH).It is likely that the management of inflammation and oxidative damage is one of the best strategies for the amelioration of these diseases after a radiological or nuclear *** the present study,we reviewed the evidence of radiation-induced diabetes and thyroid diseases,as well as the potential roles of inflammatory *** addition,we proposed that the mitigation of inflammatory and oxidative damage markers after exposure to IR may reduce the incidence of these diseases among individuals exposed to radiation.

关键词： Radiation Inflammation Autoimmune diseases Thyroid Diabetes

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Aerodynamic Simulation of A Containership to Evaluate Cargo Configuration Effect on Frontal Wind Loads

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China Ocean Engineering 2018年第2期32卷 196-205页

作者： Hamed MAJIDIAN farhood AZARSINA Department of Naval Architecture Science and Research Branch Islamic Azad University

Fuel consumption has always been a matter of concern for ships propulsion. In this research we aim to develop computer models of several containership cargo stacking configurations and discuss an optimal configuration at a constant front wind speed. The paper presents the simulation results by using ANSYS CFX for a 1:4 scale PostPanamax 9000 TEU containership. The ship is modelled in a cubic domain that contains unstructured mesh with details, in such a way that can demonstrate the influence of the container configuration on wind force. Also the numerical results are verified versus wind tunnel test data. An optimal stack configuration led to about 25%reduction in air resistance. It is proposed that in order to reduce the wind drag force and consequently reduce the fuel consumption and pollutant emissions, empty spaces between the cargo containers and unbalanced cargo distribution over the deck should be inhibited. Also, it is advised to make the cargo distribution on the most forward and aftward deck areas more streamlined.

关键词： containership numerical simulation wind force cargo stacking optimization

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Calculation of thermal neutron albedo for mono-material and bi-material reflectors

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Nuclear Science and Techniques 2018年第9期29卷 185-191页

作者： Sara Azimkhani Farhad Zolfagharpour farhood Ziaie Department of Physics University of Mohaghegh Ardabili Radiation Application Research School Nuclear Science & Technology Research Institute

Thermal neutron albedo has been investigated for different thicknesses of mono-material and bi-material reflectors. An equation has been obtained for a bi-material reflector by considering the neutron diffusion equation. The bi-material reflector consists of binary combinations of water, graphite, lead, and polyethylene. An experimental measurement of thermal neutron albedo has also been conducted for mono-material and bi-material reflectors by using a^(241) Am–Be(5.2 Ci) neutron source and a BF3 detector. The maximum value of thermal neutron albedo was obtained for a polyethylene–water combination(0.95 ± 0.02).

关键词： Neutron current Bi-material reflector Thermal neutron albedo BF3 detector Reflection Diffusion equation

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Experimental Investigation on Prototype Latent Heat Thermal Battery Charging and Discharging Function Integrated with Solar Collector

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Energy Engineering 2022年第4期119卷 1587-1610页

作者： farhood Sarrafzadeh Javadi Hendrik Simon Cornelis Metselaar Poo Balan Ganesan Department of Mechanical Engineering Faculty of EngineeringUniversity of MalayaKuala Lumpur50603Malaysia Center of Advanced Materials Faculty of EngineeringUniversity of MalayaKuala Lumpur50603Malaysia

This paper reports the performance investigation of a newly developed Latent Heat Thermal Battery(LHTB)integrated with a solar collector as the main source of *** LHTB is a new solution in the field of thermal storage and developed based on the battery concept in terms of recharge ability,portability and usability as a standalone *** is fabricated based on the thermal battery storage concept and consists of a plate-fin and tube heat exchanger located inside the battery casing and paraffin wax which is used as a latent heat storage *** thermal energy is absorbed by solar collector and transferred to the LHTB using water as Heat Transfer Fluid(HTF).Charging experiments have been conducted with a HTF at three different temperatures of 68°C,88°C and 108°C and three different flow rates of 30,60 and 120 l/*** is followed by discharging experiments on fully charged LHTB at three different temperatures of 68°C,88°C and 108°C using HTF at three different flow rates of 30,60 and 120 l/*** is found that both higher HTF inlet temperature and flow rate have a positive impact on stored thermal ***,charging efficiency was decreased by increasing the HTF flow *** highest charging efficiency of 29%was achieved using HTF of 108°C at a flow rate of 30 l/*** of paraffin melted in this case,while part of the paraffin remained solid in other *** the other hand,the results from discharging experiments revealed that both recovered thermal energy and recovery efficiency increased by either increasing the LHTB temperature or HTF flow *** recovered thermal energy of 5,825 KJ at 35%recovery efficiency achieved at LHTB of 108°C using 120 l/h of HTF.

关键词： Latent heat thermal battery phase change materials solar thermal latent heat storage thermal battery thermal storage

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Effect of Amine Type on Lignin Modification to Evaluate Its Reactivity in Polyol Construction for Non-Isocyanate Polyurethanes(NIPU)

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Journal of Renewable Materials 2023年第5期11卷 2171-2190页

作者： Saeed Kazemi Najafi farhood Najafi Antonio Pizzi Fatemeh Hassani Khorshidi Rabi Behrooz Department of Wood Science and Technology Faculty of Natural ResourcesTarbiat Modares UniversityTehranIran Department of Resin and Additives Institute for Color Science and TechnologyTehranIran LERMAB University of LorraineBlvd des AiguillettesNancyFrance

Polyols are groups of organic compounds which contain carbon and are randomly linked to other atoms,especially carbon-carbon and *** compounds are mainly used as reactants to make other *** biopolymers,lignin is regarded as the base of a new polymer in polyol *** present study aimed to investigate the effects of amine type(diethylenetriamine and ethylenediamine)on the modification of lignin-based polyols,so as to provide an alternative to petroleum polyols and,in turn,increase functional groups and reduce their harm to humans’health and the *** this aim,first,lignin was extracted from raw ***,the extracted lignin was reacted with diethylenetriamine(DETA)and ethylenediamine(EDA).Finally,the Mannich method was used for the reaction between amine lignin and propylene *** results of the Fourier Transform Infrared(FTIR)spectroscopy analysis showed that modification with DETA led to more structural change in lignin and peak 1100 indicates the presence of C–O bond related to urethane bonds in modified ***,adding propylene carbonate to aminated lignin did not result in much change in the results of the FTIR ***,urethane bonds can be seen in the results of GPC at 400℃–500℃.Furthermore,a slight decrease in thermal stability was observed in lignin modified with amine and propylene carbonate,compared to the raw lignin sample.

关键词： Polyol lignin diethylenetriamine ethylenediamine propylene carbonate polyurethanes NIPU

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Color and Gloss Changes of a Lignin-Based Polyurethane Coating under Accelerated Weathering

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Journal of Renewable Materials 2024年第2期12卷 305-323页

作者： Fatemeh Hassani Khorshidi Saeed Kazemi Najafi farhood Najafi Antonio Pizzi Dick Sandberg Rabi Behrooz Department of Wood Science and Technology Faculty of Natural ResourcesTarbiat Modares UniversityTehranIran Department of Resin and Additives Institute for Color Science and TechnologyP.O.Box 16765-654TehranIran LERMAB University of LorraineBlvd des AiguillettesNancy54000France Wood Science and Engineering LuleåUniversity of TechnologySkellefteåSweden

The purpose of this research study was to investigate the properties of polyurethane coatings based on lignin *** this purpose,the prepared coatings were applied to pine wood surfaces and weathered ***,color and gloss of the coatings were measured before and after the weathering *** emission scanning electron microscopy(FE-SEM)micrographs prepared from the coatings showed that the average size of nano-particles in the polyurethane substrate was approximately 500 *** magnetic resonance(13C-NMR)spectroscopy showed that strong urethane bonds were formed in the nano-lignin-based *** calorimetric analysis(DSC)test revealed that the glass-transition temperature(Tg)of lignin nanoparticles modified with diethylenetriamine(DETA)was 112.8℃ and Tg of lignin nano-particles modified with ethylenediamine(EDA)was 102.5℃,which is lower than the Tg of un-modified lignin(114.6℃)and lignin modified with DETA(126.8℃)and lignin modified with EDA(131.3℃).The coatings modified with lignin nano-particles had a greater change in *** lignin nano-particles in the modified coating are trapping hydroxyl radicals which reduces photoactivity and yellowing of the polyurethane by about 3 times compared to unmodified polyurethane *** weathering test,the nano-lignin-based coating had a rougher surface with a lower contact angle(0.78°)compared to the unmodified polyurethane coating(0.85°).

关键词： Amination propylene carbonate lignin biopolymer polyurethane coating polyol UN SDG 13

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Herbal extracts as hepatoprotectants against acetaminophen hepatotoxicity

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World Journal of Gastroenterology 2010年第19期16卷 2448-2450页

作者： Hartmut Jaeschke C David Williams Mitchell R McGill Anwar farhood Department of Pharmacology Toxicology and Therapeutics University of Kansas Medical Center Kansas City KS 66160 United States Department of Pathology Brackenridge Hospital Austin TX 78701 United States

Many plant-derived natural products have the potential to be hepatoprotective and therefore can be used to treat acute and chronic liver diseases. The challenge is to identify the most promising compounds and evaluate their protective mechanism. In a recently published article, Wang et al evaluated extracts of the plant Gentiana manshurica Kitagawa (GM) in a model of acetaminophen hepatotoxicity. The authors concluded that GM is hepatoprotective against acetaminopheninduced liver injury due to its antioxidant properties and anti-apoptotic capacity. We would like to discuss the limitations of this experimental approach and question the conclusion based on the data presented in this manuscript and the published literature.

关键词： Acetaminophen Drug hepatotoxicity Herbal extracts N-acetylcysteine

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Supplementation at casing to improve yield and quality of white button mushroom

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Agricultural Sciences 2013年第1期4卷 27-33页

作者： Yaqvob Mami Gholamali Peyvast Mahmood Ghasemnezhad farhood Ziaie Agricultural Medical and Industrial Research School Nuclear Science and Technology Research Institute Karaj Iran Department of Horticulture Science Faculty of Agriculture University of Guilan Rasht Iran

Supplementation of substrate at casing to increase the yield and quality of mushroom [Agaricus bisporus (Lange) Sing] is an important practice in commercial production of white button mushroom. This project was done to study the effects of supplementing the compost at casing with ground corn and soybean seed applied at: 0 gas control, 17, 34 and51 gper17 kgcompost on production and harvest quality of A. bisporus. There were significant differences between supplemented and non-supplemented substrates. The34 gsoybean and51 gcorn treatments had the highest yield. There were significant differences in quality indices of mushroom due to the type and amount of the supplement. The51 gsoybean supplement produced higher protein compared with other substrates. The highest vitamin C, total phenol, total soluble solids and antioxidant capacity obtained of 34 and51 gsoybeans or 34 and51 gcorn, respectively. Increased production and quality of A. bisporus may be achieved by addition of suitable amounts of supplements.

关键词： Agaricus bisporus Compost Corn and Soybean

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红细胞压积水平与手术预后的关系：观察的把握度

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美国医学会杂志（中文版） 2008年第1期27卷 50-51页

作者： farhood Farjah, MD David R. Flum, MD, MPH 公磊(译) 祝学光(校) Department of Surgery University of Washington Seattle. Dr Flum is Contributing Editor JAMA. 不详

在JAMA杂志中，Wu及其同事报告了行非心脏大手术的退伍军人（多为男性）术前红细胞压积水平与术后不良事件的关系。该队列研究结果显示，对于多数男性患者而言，红细胞压积高于或低于正常水平均与术后早期死亡和心脏事件发生危险增加相... 详细信息

在JAMA杂志中，Wu及其同事报告了行非心脏大手术的退伍军人（多为男性）术前红细胞压积水平与术后不良事件的关系。该队列研究结果显示，对于多数男性患者而言，红细胞压积高于或低于正常水平均与术后早期死亡和心脏事件发生危险增加相关。作者建议，今后的研究应进一步评估通过纠正贫血或红细胞增多症来降低术后不良事件危险的影响。

关键词：红细胞压积手术预后积水把握度非心脏大手术术后早期死亡红细胞增多症不良事件

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椭圆中空截面的塑性交互作用

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钢结构(中英文) 2009年第6期 81-81页

作者： farhood Nowzartash Magdi Mohareb

建立了计算轴压、双轴弯矩和扭转组合作用下的椭圆中空钢截面的交互作用公式。公式基于塑性下限定理和最大畸变能密度屈服准则而建立。交互作用公式中包括一系列无量纲的椭圆积分,并可以预测屈服曲面上的内力组合。为计算内力组合选用... 详细信息

建立了计算轴压、双轴弯矩和扭转组合作用下的椭圆中空钢截面的交互作用公式。公式基于塑性下限定理和最大畸变能密度屈服准则而建立。交互作用公式中包括一系列无量纲的椭圆积分,并可以预测屈服曲面上的内力组合。为计算内力组合选用了一系列测试公式和简化的交互作用公式。交互作用包括普通尺寸EHS截面的轴力、双轴弯矩和扭矩的组合内力。最后采用实例验证了这个公式在计算钢结构横截面交互作用中的有效性。

关键词：钢椭圆中空截面塑性屈服曲面交互作用

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