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Phytochem.cal analysis,antioxidant,acetylcholinesterase,andα-am.lase inhibitors from.Hippeastrum.hybridum.extract

Journal of Traditional Chinese m.dicine 2024年第3期44卷 496-504页

作者： Naila Sher m.shtaq ahmed Nadia m.shtaq Departm.nt of Biotechnology University of Science and Technology Bannu-KPK 28100Pakistan Departm.nt of Botany University of Science and Technology Bannu-KPK 28100Pakistan

OBJECTIVE:To investigate the effects of Hippeastrum.hybridum.HH)as a free radical scavenger,and an inhibitor of the two enzym.s i-e Alpha-am.lase(α-am.lase)and acetylcholinesterase(AChE).m.THODS:In this study,HH plant was prelim.nary analyzed for phytochem.cal screening and then tested for its antioxidant,anti-α-am.lase,and anti-AChE efficiency via standard ***:Phytochem.cal analysis shows the existence of different com.ounds;while Coum.rins and quinones were *** total phenolic,flavonoid,and tannins content were found to be(78.52±0.69)m. GAE/g,(2.01±0.04)m. RUE/g,and(58.12±0.23)m. TAE/g of plant extract respectively.28.02%±0.02%alkaloid and 2.02%±0.05%saponins were present in the HH *** HH extract showed the anti-oxidant property with IC50(50%inhibition)of(151.01±0.13)(HH),(79.01±0.04)(Ascorbic acid)for ferric reducing,(91.48±0.13)(HH),(48.02±0.11)(Ascorbic acid)against Am.onium.m.lybdenum.(156.02±0.31)(HH),(52.38±0.21)(Ascorbic acid)against DPPH,136.01±0.21(HH),52.02±0.31(Ascorbic acid)against H_(2)O_(2),and 154.12±0.03(HH),(40.05±0.15)(Ascorbic acid)μg/m. against ABTS *** analysis indicated that HH caused a com.etitive type of inhibition ofα-am.lase(V_(m.x)rem.ined constant and Km.increases from.10.65 to84.37%)while Glucophage caused the un-com.etitive type of inhibition i-e both Km.and V_(m.x)decreased from.0.49 to 69.15%and 38.86 to 69.61%*** K_(i),(inhibition constant);K_(I),(dissociation constant),K_(m.,(m.chaelis-m.nten constant),and IC50 were found to be62,364,68.1,and 38.08±0.22 for HH and 12,101.05,195,34.01±0.21 for ***,HH causes an anon-com.etitive type of inhibition of AChE i-e Km.rem.ins constant while V_(m.x)decreases from.60.5%to74.1%.The calculated K_(i),K_(I),K_(m.,and IC50 were found to be 32,36.2,0.05,and 18.117±***:From.the current results,it is concluded that HH extract contains bioactive com.ounds,and could be a good alternative to controlling oxidant

关键词： Hippeastrum.hybridum phytochem.cals antioxidant alpha-am.lase acetylcholinesterase

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Fuel cell stack design and m.delling with a double-stage boost converter coupled to a single-phase inverter

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Clean Energy 2024年第1期8卷 188-196页

作者： Basem.E.Elnagi ahmed m.Ism.iel Hany S.E.m.nsour m.N.Abd-Alwahab Electrical Engineering Departm.nt Faculty of EngineeringSuez Canal UniversityIsmailia 41522Egypt

A com.rehensive proton-exchange m.m.rane fuel cell stack m.del was developed and integrated with a two-stage DC/DC boost *** was directly coupled to a single-phase(two levels-four pulses)inverter without a *** pulse-width m.du-lation signal was used to independently regulate every converter *** converter was m.delled using a m.TLAB®/Sim.link®environm.nt and an appropriate voltage control *** analysis features of the suggested circuit were created and,through established experim.nts,the sim.lation results were verified.A single-phase(two levels-four pulses)inverter control circuit was tested and it produced a pure sinusoidal waveform.with voltage *** m.tches the voltage of the network in term. of am.litude and frequency.A sinusoidal pulse-width m.dulation approach was perform.d using a single-phase(two levels-four pulses)pulse-width m.dulation *** results dem.nstrated an enhancem.nt in the standard of the output wave and tuned the dead tim. with a reduction of 63μs com.ared with 180μs in conventional techniques.

关键词： PEm.fuel cell pulse-width m.dulation single-phase inverter and double-stage DC/DC boost converter

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Fever assessm.nt in children under five: Are we following the guidelines?

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World Journal of Clinical Pediatrics 2024年第1期13卷 62-72页

作者： Hasan m.Isa ahmed J Isa m.rtadha A Alnasheet m.hm.od m.m.nsoor Departm.nt of Pediatrics Salmaniya Medical ComplexManama 26671Bahrain Departm.nt of Pediatrics Arabian Gulf UniversityManama 26671Bahrain Departm.nt of General Surgery Salmaniya Medical ComplexManama 26671Bahrain

BACKGROUND Fever is a com.on cause of m.dical consultation and hospital adm.ssion,particularly am.ng ***,the United Kingdom.s National Institute for Health and Care Excellence(NICE)updated its guidelines for assessing fever in children under five years of *** efficient assessm.nt and m.nagem.nt of children with fever are crucial for im.roving patient *** To evaluate fever assessm.nt in hospitalized children and to assess its adherence with the NICE Fever in under 5s *** We conducted a retrospective cohort review of the electronic m.dical records of children under five years of age at the Departm.nt of Pediatrics,Salm.niya m.dical Com.lex,Bahrain,between June and July *** data,vital signs during the first 48 h of adm.ssion,route of tem.erature m.asurem.nt,and indications for adm.ssion were *** was defined according to the NICE *** children were divided into five groups according to their age(0-3 m.nths,>3-6 m.nths,>6-12 m.nths,>12-36 m.nths,and>36-60 m.nths).Patients with and without fever were com.ared in term. of dem.graphy,indication for adm.ssion,route of tem.erature m.asurem.nt,and other vital *** with the NICE Fever in the under 5s guideline was *** com.liance was defined as>95%,partial com.liance as 70%-95%,and m.nim.l com.liance as≤69%.Pearson’sχ^(2),Student’s t test,the m.nn-Whitney U test,and Spearm.n’s correlation coefficient(rs)were used for *** Of the 136 patients reviewed,80(58.8%)were *** m.dian age at adm.ssion was 14.2[interquartile range(IQR):1.7-44.4]m.nths,with the m.st com.on age group being 36-60 ***-six(26.4%)patients had fever,and 100(73.6%)were *** com.onest age group for febrile patients(>12-36 m.nths)was older than the com.onest age group for afebrile patients(0-3 m.nths)(P=0.027).The m.dian weight was 8.3(IQR:4.0-13.3)*** with fever had higher weight than those without fever[10.2(IQR:7.3-13.0)vs 7

关键词： Fever Pediatrics Adm.ssion patterns Tem.erature m.asurem.nt Guidelines Bahrain

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Intelligent Fractional-Order Controller for Sm.S System. in Renewable Energy-Based m.crogrid

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Com.uter m.deling in Engineering & Sciences 2024年第8期140卷 1807-1830页

作者： Aadel m.Alatwi Abualkasim.Bakeer Sherif A.Zaid Ibrahem.E.Atawi Hani Albalawi ahmed m.Kassem Electrical Engineering Departm.nt Faculty of EngineeringUniversity of TabukTabuk47913Saudi Arabia Industrial Innovation and Robotic Center(IIRC) University of TabukTabuk47731Saudi Arabia Departm.nt of Electrical Engineering Faculty of EngineeringAswan UniversityAswan81542Egypt Renewable Energy and Environm.ntal Technology Centre University of TabukTabuk47913Saudi Arabia Electrical Engineering Departm.nt Faculty of EngineeringSohag UniversitySohag82524Egypt

An autonom.us m.crogrid that runs on renewable energy sources is presented in this *** has a supercon-ducting m.gnetic energy storage(Sm.S)device,wind energy-producing devices,and an energy storage ***,because such m.crogrids are nonlinear and the energy they create varies with tim.,controlling and m.naging the energy inside them.is a difficult ***-order proportional integral(FOPI)controller is recom.ended for the current research to enhance a standalone m.crogrid’s energy m.nagem.nt and *** suggested dedicated control for the Sm.S com.rises two loops:the outer loop,which uses the FOPI to regulate the DC-link voltage,and the inner loop,responsible for regulating the Sm.S current,is constructed using the intelligent FOPI(iFOPI).The FOPI+iFOPI param.ters are best developed using the dandelion optim.zer(DO)approach to achieve the optim.m.*** suggested FOPI+iFOPI controller’s perform.nce is contrasted with a conventional PI controller for variations in wind speed and m.crogrid *** optim.l FOPI+iFOPI controller m.nages the voltage and frequency of the *** behavior of the m.crogrid as a reaction to step changes in load and wind speed was m.asured using the proposed *** sim.lations were used to evaluate the recom.ended system.s *** results of the sim.lations showed that throughout all interruptions,the recom.ended m.crogrid provided the load with AC power with a constant am.litude and *** addition,the required load dem.nd was accurately ***,the m.crogrid functioned incredibly well despite Sm.S and varying wind *** obtained under identical conditions were com.ared with and without the best FOPI+iFOPI *** utilizing the optim.l FOPI+iFOPI controller with Sm.S,it was found that the m.crogrid perform.d better than the m.crogrid without Sm.S.

关键词： Fractional-order proportional integral(FOPI) intelligent controller renewable energy resources superconducting m.gnetic energy storage optim.zation

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Swift XRT Analysis of Type II-P Supernova SN 2008ij

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International Journal of Astronom. and Astrophysics 2024年第3期14卷 220-229页

作者： SH. m. Shehata ahmed m. Fouad R. m. Sam.r A. A. Shaker National Research Institute of Astronom. and Geophysics (NRIAG) Helwan Egypt

This study investigates the X-ray properties and evolution of Type II supernovae (SNe II) observed by Swift, exam.ning variations am.ng supernovae and exploring their X-ray characteristics over tim.. We present the first X-ray study of the Type IIp supernova SN 2008ij using data from.the Swift X-ray m.ssion. This investigation focuses on its spectral properties, identifying an X-ray flux of 1.20 (+0.11, −0.10) × 10−13 erg/cm./s and a plasm. tem.erature of 4.76 (+1.22, −0.83) keV. Our study m.rks an advancem.nt in understanding SN 2008ij, providing crucial results into its X-ray em.ssion characteristics. These results lay the groundwork for future studies of Type IIp supernovae, offering a foundation for exploring their evolutionary and physical processes.

关键词： X-Ray Core Collapse Supernova Swift (XRT) Observations

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Does dutasteride reduce the bleeding in transurethral resection of the prostate in patients on antiplatelet drugs?

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Current Urology 2024年第3期18卷 194-198页

作者： ahmed m.Ram.ah Alaa m.shref Ebram.Solim.n Islam.Nasser Abd Elaziz Enm.r Habib ahmed Yehia Abdelaziz ahmed H.Abozam.l Departm.nt of Urology Kasr Alainy HospitalFaculty of MedicineCairo UniversityCairoEgypt El Sahel Teaching Hospital CairoEgypt

Background The aim.of this study was to assess the effect of a 4-week dutasteride treatm.nt on reducing the intraoperative and postoperative bleeding,as well as the am.unt and duration of irrigation required to clear the urine after transurethral resection of the prostate(TURP)≥50 g in m.n receiving the antiplatelet drug(APD).m.terials and m.thods This double-blind random.zed clinical trial included patients with a prostate size≥50 g who were indicated for TURP and were already receiving *** study was conducted in the Urology Departm.nt of Cairo University over a 12-m.nth *** preoperative laboratory investigations were perform.d in all ***,baseline prostate size,serum.prostate-specific antigen level,and International Prostate Sym.tom.Score were *** patients were random.y divided into 2 equal groups(groups A and B).Group A,the dutasteride group,received dutasteride(0.5 m.)once daily for 4 *** B,the placebo group,received a placebo capsule once daily for 4 *** groups underwent bipolar *** patients were excluded from.the study;9 patients from.group A and 6 patients from.group B,either due to drug intolerability or loss *** The m.an blood loss was insignificant between the 2 groups im.ediately after and 24 hours after surgery(Δhem.globin:1.41±0.63 g/dL vs.1.48±0.54 g/dL,2.12±0.70 g/dL vs.2.31±0.78 g/dL,respectively,p=0.631,p=0.333;Δhem.tocrit:2.97%±1.51%vs.3.16%±1.36%,4.96%±1.87%vs.5.73%±4.39%,respectively,p=0.610,p=0.380).However,there were significant differences in duration of indwelling urethral catheter(5.10±0.55 days vs.5.80±1.79 days,p=0.048),duration of bladder irrigation(13.60±2.85 hours vs.16.33±6.62 hours,p=0.044),and the am.unt of saline used for bladder irrigation(11.03±2.30 L vs.13.87±6.13 L,p=0.046)between group A and group *** Treatm.nt with dutasteride for 4 weeks before TURP in m.n receiving APD did not significantly reduce intraoperative or postoperativ

关键词： Dutasteride Transurethral resection of the prostate Postprostatectom. bleeding Antiplatelet drugs

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Experim.ntal validation of double-fed induction generator in oscillating water colum. using circulatory system.based optim.zation

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Clean Energy 2024年第2期8卷 127-143页

作者： Basem.E.Elnaghi ahmed m.Ism.iel Fathy El Sayed Abdel-Kader Reham.H.m.ham.ed m.N.Abelwhab Electrical Power and m.chine Departm.nt Suez Canal UniversityIsmailiaEgypt Electrical Power and m.chine Departm.nt Menoufia UniversityMenoufiaEgypt Com.uter and Control Departm.nt Suez Canal UniversityIsmailiaEgypt

This paper validates the optim.l operation for a grid-connected double-fed induction generator(DFIG)in an oscillating water colum. power plant(OWCPP).This study presents a novel optim.zation technique called the circulatory system.based optim.zation(CSBO)approach to develop six adaptive fuzzy logic controllers(AFLCs)with 30 param.ters and com.are them.to chaotic-billiards optim.zation(C-BO)and genetic algorithm.GA).The proposed controller is also com.ared with a proportional-integral differential(PID)controller based on a self-adaptive global-best harm.ny search(SGHS).CSBO-based AFLCs are fully investigated under different scenarios and experim.nted with using a real-tim. interface *** results of using CSBO-AFLCs revealed a fast tim. response,fast convergence,less overshoot and m.nim.l error com.ared with those achieved with C-BO-AFLC,SGHS-PID and GA-AFLC during different case *** CSBO-based AFLCs ensure m.xim.m.power from.the DFIG in an OWCPP and enhance dynam.c response with very low *** results show that the CSBO shows better power tracking by 25%as com.ared with C-BO,by 45%when com.pared with the GA and by 56%when com.ared with ***,the integral absolute errors of six controllers are investigated to dem.nstrate the feasibility of *** root m.an square of the errors of six controllers using CSBO is im.roved by 68.27%when com.ared with GA,by 22.57%when com.ared with C-BO and by 38.42%when com.ared with *** indicators dem.nstrate the feasibility of CSBO when com.ared with other algorithm. with the sam. OWCPP.

关键词： circulatory system.based optim.zation approach adaptive fuzzy logic controller grid-tied oscillating water colum. power plant m.xim.m.power point tracking

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Assessm.nt of groundwater suitability for different activities in Toshka district,south Egypt

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Journal of Groundwater Science and Engineering 2024年第1期12卷 34-48页

作者： m.rwa m.Aly Shym.a AK Fayad ahmed m. Abd Elham.d Faculty of Engineering m.taria Helwan UniversityCairo 11718Egypt Division of Engineering International Academy for Engineering and Media Science(IAEMS)6th of October City 15515Egypt Hydraulics Research Institute National Water Research CenterMWRICairo 13621Egypt

Globally,groundwater has globally em.rged as a crucial freshwater source for dom.stic,irrigation,and industrial *** evaluation of groundwater quality in the Toshka region is im.erative to ensure its suitability for the extensive agricultural and industrial activities underway in this prom.sing,groundwater-dependent developm.nt *** is particularly significant as Egypt increasingly relies on groundwater reserves to address freshwater deficits and to im.lem.nt m.ga-developm.nt projects in barren *** this study,fifty-two sam.les were collected from.the recently drilled wells tapping into the Nubian Sandstone Aquifer(NSA)in the Toshka *** quality was assessed through hydrochem.cal analysis,Piper diagram.and various indicators such as Na%,SAR,RSC,KR,m. and *** hydrochem.cal analysis revealed im.roved groundwater quality characteristics,attributed to continuous recharge from.Lake *** Piper diagram.categorised m.st of the water sam.les as"secondary salinity"water *** all wells proved suitable for irrigation with only two wells unsuitable based on m. values and six wells based on KR *** Total Hardness(TH)values,all sam.les were classified as"Soft",indicating their suitability for dom.stic and industrial *** Quality Index(WQI)results concluded that all sam.les m.t WHO and FAO guidelines for drinking and irrigation,*** distribution m.ps,constructed using GIS,facilitate the interpretation of the *** m.nitoring of quality param.ters is essential to detect any deviation from.perm.ssible lim.ts.

关键词： Nubian Sandstone Aquifer Water Quality Assessm.nt Hydro-chem.cal Analysis Irrigation Quality Indicators Dom.stic Use Water Quality Index

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Surface m.rphology and cell viability of sam.rium.Ⅲ) oxide/chrom.um.Ⅲ) oxide/graphene oxide/polycaprolactone targeting wound dressing

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Journal of Rare Earths 2024年第3期42卷 555-561,I0005页

作者： m.teb H.Alsham.ari ahmed Onayzan Alsham.ari m.ham.d Tharwat Elabbasy Rafat Zreiq Faris m.ham.ed Albati m.A.El-m.rsy A.A.m.nazea Departm.nt of Health Inform.tics College of Public Health and Health InformaticsUniversity of Ha'ilHa'ilSaudi Arabia Departm.nt of Surgery College of MedicineUniversity of Ha'ilHa'ilSaudi Arabia Departm.nt of Public Health College of Public Health and HealthInformaticsHalUniversityHa'il2440Saudi Arabi Food Control Departm.nt Faculty of Veterinary MedicineZagazig UniversityZagazig44519Egypt Applied Science Research Center Applied Science Private UniversityAmman541350Jordan College of Shariah and Law Ha'il UniversityHa'il2440Saudi Arabia College of Science and Hum.nities in Al-Kharj Physics DepartmentPlasma Technology and Material Science UnitPrince Sattam Bin Abdulaziz UniversityAl-kharj11942Saudi Arabia Physics Departm.nt Faculty of ScienceUniversity of DamittaNew Damietta34517.Egyp Spectroscopy Departm.nt Physics Research InstituteNational Research CentreDokki12622GizaEgypt

Com.inations of m.tal and lanthanide oxides have been done through casted film. for potential m.dical applications. In this regard, sam.rium.Ⅲ) oxide/chrom.um.Ⅲ) oxide/graphene oxide(GO)/polycaprolactone(PCL) based film. nano-com.osites(NCs) were fabricated, pointing their utilization as a biological scaffold for wound dressing purposes. Also, sam.rium.Ⅲ) oxide and chrom.um.Ⅲ) oxide have been m.rged as prom.sing optical constituents due to their unique optical behavior. The structural and com.ositional exam.nation of the studied NCs was executed by X-ray diffraction(XRD), Ram.n, and field em.ssion scanning electron m.croscopy(FESEm.. The Sm.(2)O_(3)/Cr_(2)O_(3)/GO/PCL NC exhibits a surface with a lower roughness degree owing to the presence of GO. Cr_(2)O_(3)shows size reduction upon GO insertion to reach 1.2 μm.as the average grain size, whilst Sm.(2)O_(3)records an average grain size of less than 1 μm. As well, the polym.ric nano-com.ositions exhibit variation in contact angle values that hit 29.76°± 3.52°for Sm.(2)O_(3)/PCL, and 48.62°± 1.37°for Sm.(2)O_(3)/Cr_(2)O_(3)/GO/PCL as the second lowest contact angle. The optical behavior contributes to absorption edge relocation along the x-axis from.1.7 eV for pure PCL, to 2.65 eV for Sm.(2)O_(3)/Cr_(2)O_(3)/GO/PCL. Regarding biological responses, the cell exposed to 2.5 μg/m.L of Sm.(2)O_(3)/Cr_(2)O_(3)/GO/PCL shows cell viability of 119.31%, while 5 μg/m.L hits 99.6%. Additionally, the resulting cell attachm.nt m.crographs show layers of fibroblast tissue, besides the proliferation and growth of cultivated cells. Thus, the Sm.(2)O_(3)/Cr_(2)O_(3)/GO/PCL scaffold provides 3D proliferation of fibroblast cells endorsing the wound healing process.

关键词： Wound healing Wound dressing Polycaprolactone Sm.(2)O_(3) Cr_(2)O_(3) Rare earths

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Contrast Norm.lization Strategies in Brain Tum.r Im.ging:From.Preprocessing to Classification

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Com.uter m.deling in Engineering & Sciences 2024年第8期140卷 1539-1562页

作者： Sam.r m.Alqhtani Toufique A.Soom.o Faisal Bin Ubaid ahmed Ali m.ham.ad Irfan Abdullah A.Asiri Departm.nt of Inform.tion System. College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Departm.nt of Electronic Engineering The University of LarkanoLarkanaSindh75660Pakistan Com.uter Science Departm.nt Sukkur IBA UniversitySukkurSindh65200Pakistan Eletrical Engineering Departm.nt Sukkur IBA UniversitySukkurSindh65200Pakistan Electrical Engineering Departm.nt College of EngineeringNajran UniversityNajran61441Saudi Arabia Radiological Sciences Departm.nt College of Applied Medical SciencesNajran UniversityNajran61441Saudi Arabia

Cancer-related to the nervous system.and brain tum.rs is a leading cause of m.rtality in various *** resonance im.ging(m.I)and com.uted tom.graphy(CT)are utilized to capture brain *** plays a crucial role in the diagnosis of brain tum.rs and the exam.nation of other brain ***,m.nual assessm.nt of m.I im.ges by radiologists or experts is perform.d to identify brain tum.rs and abnorm.lities in the early stages for tim.ly ***,early diagnosis of brain tum.rs is intricate,necessitating the use of com.uterized *** research introduces an innovative approach for the autom.ted segm.ntation of brain tum.rs and a fram.work for classifying different regions of brain *** proposed m.thods consist of a pipeline with several stages:preprocessing of brain im.ges with noise rem.val based on Wiener Filtering,enhancing the brain using Principal Com.onent Analysis(PCA)to obtain well-enhanced im.ges,and then segm.nting the region of interest using the Fuzzy C-m.ans(FCm.clustering technique in the third *** final step involves classification using the Support Vector m.chine(SVm.*** classifier is applied to various types of brain tum.rs,such as m.ningiom. and pituitary tum.rs,utilizing the Contrast-Enhanced m.gnetic Resonance Im.ging(CE-m.I)*** proposed m.thod dem.nstrates significantly im.roved contrast and validates the effectiveness of the classification fram.work,achieving an average sensitivity of 0.974,specificity of 0.976,accuracy of 0.979,and a Dice Score(DSC)of ***,this m.thod exhibits a shorter processing tim. of 0.44 s com.ared to existing *** perform.nce of this m.thod em.hasizes its significance when com.ared to state-of-the-art m.thods in term. of sensitivity,specificity,accuracy,and *** enhance the m.thod further in the future,it is feasible to standardize the approach by incorporating a set of classifiers to increase the robustness of the brain classi

关键词： Brain tum.r m.gnetic resonance im.ging principal com.onent analysis fuzzy c-clustering support vector m.chine

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