检索结果-南通市图书馆

Chinese Journal of Chemical Engineering 2024年第5期69卷 34-46页

作者： Jun Qiu Lu-ri bao Wei Guo Ying Yang Shu-Ying Sun National Engineering Research Center for Integrated Utilization of Salt Lake Resource East China University of Science and TechnologyShanghai 200237China

Gas-produced water is an accompanying wastewater in the natural gas extraction process,and it is a potential liquid lithium resource that contains a considerable amount of *** study investigated the feasibility of using manganese-based ion sieves to adsorb and extract lithium from gas-produced *** we focused on the applicability of two different granulation methods,extrusion and droplet,in gas-produced water *** types of H_(1.33)Mn_(1.67)O_(4) particles were prepared by the extrusion method(EHMO)and the droplet method(DHMO).The porosity of DHMO was much higher than that of EHMO,and the adsorption performance of DHMO increased with the decrease of binder *** prepared with a binder concentration of 0.14 g·ml^(-1)exhibited the best adsorption performance in gas-produced water,and the Li^(+)adsorption capacity could reach 25.14 mg·g^(-1).In gas-produced water,the adsorption equilibrium of DHMO only took 9 h,and the adsorption process conformed to the Langmuir model and pseudo-second-order kinetic *** pore diffusion model(PDM)could well describe its adsorption ***,DHMO showed a great selectivity to Li^(+),and the selectivity order of DHMO in gas-produced water was Li^(+)>ba^(2+)>>Mg^(2+),Ca^(2+),Sr^(2+)>>Na^(+)>>K^(+).After 20 cycles,the Li^(+)adsorption capacity was still higher than 17.30 mg·g^(-1),and the rate of manganese dissolution was less than 1%.

关键词： Gas-produced water Granulation Li_(1.33)Mn_(1.67)O_(4)

协日嘎-4味散成分组成分析及6种成分含量测定

在线全文

学校读者我要写书评

暂无评论

中成药 2024年第1期46卷 14-22页

作者：李君王跃武张谦翠平叶日贵吉日木巴图内蒙古医科大学药学院内蒙古呼和浩特010110 内蒙古医科大学新药筛选工程研究中心内蒙古呼和浩特010110 内蒙古医科大学民族医药创新中心内蒙古呼和浩特010110

目的分析协日嘎-4味散成分组成,并测定黄柏碱、绿原酸、栀子苷、小檗碱、芦丁、姜黄素的含量。方法高效液相色谱-四级杆/静电场轨道阱高分辨质谱(HPLC-Q-Exactive-MS)定性分析采用Agilent ZORbaX SB-Aq色谱柱(4.6 mm×150 mm,5μm);流... 详细信息

目的分析协日嘎-4味散成分组成,并测定黄柏碱、绿原酸、栀子苷、小檗碱、芦丁、姜黄素的含量。方法高效液相色谱-四级杆/静电场轨道阱高分辨质谱(HPLC-Q-Exactive-MS)定性分析采用Agilent ZORbaX SB-Aq色谱柱(4.6 mm×150 mm,5μm);流动相甲醇-0.1%甲酸,梯度洗脱;体积流量0.35 mL/min;柱温35℃;电喷雾离子源;正负离子扫描。高效液相色谱串联三重四级杆质谱(HPLC-MS/MS)定量分析采用Shim-pack GIST-HP C_(18)色谱柱(2.1 mm×100 mm,3μm);流动相甲醇-0.1%甲酸;体积流量0.25 mL/min;柱温35℃;电喷雾离子源;正负离子扫描;多反应监测模式。结果共鉴定出65种成分,包括19种生物碱、13种有机酸、13种黄酮、7种姜黄素、6种环烯醚萜、4种脂肪酸、2种醛、1种氨基酸。6种成分在各自范围线性关系良好(r≥0.9991),平均加样回收率96.44%~102.37%,RSD 2.05%~3.74%。结论本研究可为协日嘎-4味散的质量控制提供参考。

关键词：协日嘎-4味散成分组成化学成分含量测定高效液相色谱-四级杆/静电场轨道阱高分辨质谱(HPLC-Q-Exactive-MS) 高效液相色谱串联三重四级杆质谱(HPLC-MS/MS)

Inbreeding and genetic load in a pair of sibling grouse species:Tetrastes sewersowi and ***

在线全文

学校读者我要写书评

暂无评论

Avian Research 2024年第2期15卷 265-270页

作者： Kai Song Tom van der Valk Bin Gao Peter Halvarsson Yun Fang Wendong Xie Siegfried Klaus Zhiming Han Yue-Hua Sun Jacob Hoglund Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing100101China Animal Ecology Department of Ecology and GeneticsUppsala UniversityNorbyvagen 18DUppsala75236Sweden Department of Cell and Molecular Biology Uppsala75273Sweden Unit of Parasitology Department of Biomedicine and Veterinary Public HealthSwedish University of Agricultural SciencesPO Box 7036Uppsala75007Sweden Lindenhohe 5 JenaD-07749Germany The State Key Laboratory of Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing100101China

Genetic load and inbreeding are recognized as important factors to be considered in conservation *** levels of both can increase the risk of population extinction by negatively impacting fitness-related characters in many species of plants and animals,including humans(inbreeding depression).Genomic tech-niques are increasingly used in measuring and understanding genetic load and inbreeding and their importance in evolution and *** used whole genome resequencing data from two sibling grouse species in subarctic Eurasia to quantify *** found a large range of inbreeding measured as FROH(fraction of runs of homozygosity)in individuals from different populations of Chinese Grouse(Tetrastes sewerzowi)and Hazel Grouse(***).FROH estimated from genome-wide runs of homozygosity(ROH)ranged from 0.02 to 0.24 among Chinese Grouse populations and from 0.01 to 0.44 in Hazel *** from a population of Chinese Grouse residing in the Qilian mountains and from the European populations of Hazel Grouse(including samples from Sweden,Germany and Northeast Poland)were the most inbred(FROH ranged from 0.10 to 0.23 and 0.11 to 0.44,respectively).These levels are comparable to other highly inbred populations of *** Grouse from northern China and Chinese Grouse residing in the Qinghai-Tibetan Plateau showed relatively lower inbreeding *** of the ratio between deleterious missense mutations and synonymous mutations revealed higher levels in Chinese Grouse as compared to Hazel *** results are possibly explained by higher fixation rates,mutational melt down,in the range-restricted Chinese Grouse compared to the wide-ranging Hazel ***,when we compared the relatively more severe class of loss-of-function muta-tions,Hazel Grouse had slightly higher levels than Chinese Grouse,a result which may indicate that purifying selection(purging)has been more efficient in Chinese Grouse on this class of mutations.

关键词： Genetic load Inbreeding Purifying selection Qinghai-Tibetan Plateau ROH Tetrastes

治疗早期阿尔茨海默病的潜在药物:Donanemab注射液

在线全文

学校读者我要写书评

暂无评论

中国临床药理学杂志 2024年第9期40卷 1372-1374页

作者：敖日格勒宝力高万全白国柱呼格吉乐巴图内蒙古民族大学附属医院中西医结合普外科内蒙古通辽028000 内蒙古民族大学附属医院中西医结合心内科内蒙古通辽028000 内蒙古民族大学附属医院中西医结合脑病科内蒙古通辽028000

Donanemab注射液是一种突破性Aβ靶向新药,针对抗β淀粉样蛋白的抗体药物,主要适用于早期阿尔茨海默病。临床前研究发现其能改善海马和大脑皮质层的淀粉样蛋白沉积情况,临床试验显示其能调节认知能力和日常生活活动能力方面问题。本文对... 详细信息

Donanemab注射液是一种突破性Aβ靶向新药,针对抗β淀粉样蛋白的抗体药物,主要适用于早期阿尔茨海默病。临床前研究发现其能改善海马和大脑皮质层的淀粉样蛋白沉积情况,临床试验显示其能调节认知能力和日常生活活动能力方面问题。本文对Donanemab注射液目前存在的研究进行介绍,以期增强对前沿新药的认识。

关键词：阿尔茨海默病 Donanemab注射液早期症状

More common RNAemia in the early stage of severe SARS-CoV-2 BF.7.14 infections in pediatric patients

在线全文

学校读者我要写书评

暂无评论

Biosafety and Health 2024年第1期6卷 5-11页

作者： Yu Sun Runan Zhu Yang Pan ri De Shuang Liu Liping Jia Bing Lv Xiaoyun Li Dongmei Chen Yao Yao Dong Qu Daitao Zhang Linqing Zhao Laboratory of Virology Bejing Key Laboratory of Etiology of Viral Diseases in ChildrenCapital Institute of PediatricsBejing 100020China Institute for Infectious Disease and Endemic Disease Control Bejing Center for Disease Control and Prevention Beijing 100013China Department of Intensive Care Unit Affiliated Children's Hospital of Capital Institute of PediatricsBeijing 100020China

The risk factors of severe infections in children during the severe acute respiratory syndrome coronavirus 2(SARS‐CoV‐2)outbreak in Beijing remain ***‐CoV‐2‐positive children admitted to the intensive care unit(ICU)with collected plasma specimens were enrolled and screened for common pathogens using capillary electrophoresis‐based multiplex PCR from December 12,2022,to January 24,*** SARS‐CoV‐2 subvariants were identified using next‐generation *** was positive for two(positive;P),one(suspicious;S),or no(negative;N)SARS‐CoV‐2 genes were classified as plasmatic RNA‐positive(RNAemia;P+S)or without RNAemia(N).Clinical and laboratory data of the enrolled cases were then collected and *** 34 enrolled children included 26 males and 24 younger than three *** were negative for other respiratory ***.7.14(18/29)was the predominant *** loads in respiratory specimens,hours from symptom onset to the first respiratory specimen collection(time‐variable),with comorbidities and BF.7.14 and ba.5.2 distributions were significantly different in P vs.N and RNAemia *** RNAemia *** most cases,the T lymphocyte ratios decreased,while the cytokine level and the B lymphocyte ratio *** time variables were 2.22±2.05 and 4.00±2.49 days in BF.7.14 and ba.5.2 infections,*** conclusion,SARS‐CoV‐2 was more likely to cause severe infections among males aged≤3 years old with comorbidities during the SARS‐CoV‐2 outbreak in Beijing,while RNAemia is more common in children at the early stage of severe BF.7.14 infections,and most had high cytokine levels and B‐cell activation.

关键词： Severe SARS‐CoV‐2 infection Pediatric patients risk factor RNAemia BF.7.14

Two new xanthones from Lomatogonium carinthiacum

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2014年第9期12卷 693-696页

作者： ba-gen-na CHEN Yu-Lan baderihu TONG Yu-Feng Ye-ri-gui WANG Qing-Hu College of Traditional Mongolian Medicine Inner Mongolia University for Nationalities

AIM: To study the chemical constituents of Lomatogonium carinthiacum(Wulfen) Rchb. METHOD: The CHCl3-soluble fraction was separated by chromatography and the structures of the new compounds were elucidated by spectral experiments. RESULTS: Two new xanthones, 1, 8-dihydroxy-4, 5-dimethoxy-6, 7-methylenedioxyxanthone(1), 1, 4, 8-trimethoxyxanthone-6-O-β-D-glucoronyl-(1→6)O-β-D-glucoside(2) were isolated from the whole plant of Lomatogonium carinthiacum. CONCLUSION: Compounds 1 and 2 are new natural products.

关键词： dihydroxy dimethoxy glucoside elucidated separated methoxyl silica spectroscopic elucidation Gentianaceae

凹坑织构化81107轴承变载摩擦磨损性能研究

在线全文

学校读者我要写书评

暂无评论

机械设计与制造 2024年第3期 305-309页

作者：金志浩韩辉龙日升张义民沈阳化工大学装备可靠性研究所辽宁沈阳110142

为了探究变载条件下凹坑织构化轴承的摩擦磨损性能,以81107TN推力圆柱滚子轴承为研究对象,通过在轴圈表面制备不同直径和不同深度的凹坑型织构,利用MMW-1A型万能摩擦磨损试验机,在阶梯渐进增长式载荷和贫油条件下进行试验。通过分析和... 详细信息

为了探究变载条件下凹坑织构化轴承的摩擦磨损性能,以81107TN推力圆柱滚子轴承为研究对象,通过在轴圈表面制备不同直径和不同深度的凹坑型织构,利用MMW-1A型万能摩擦磨损试验机,在阶梯渐进增长式载荷和贫油条件下进行试验。通过分析和对比试验后的摩擦系数、磨损量以及表面形貌,发现:直径250μm、深度20μm的凹坑织构化轴承表现出良好的摩擦磨损性能,其平均摩擦系数上升时间点比光滑无织构轴承滞后6000s,磨损量相比光滑无织构轴承降低7%;这里的条件下,变载荷条件下轴承的平均摩擦系数比恒定载荷低,最大差值为0.031,且后期变载荷轴承平均摩擦系数更稳定,变载荷轴承磨损量相比恒定载荷轴承也减少了7.3%。

关键词：凹坑织构滚动轴承摩擦磨损贫油润滑

Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2020年第4期17卷 380-394页

作者： Christian Orlik Daniel Deibel Johanna Küblbeck Emre balta Sabina Ganskih Jüri Habicht Beate Niesler Jutta Schröder-Braunstein Knut Schäkel Guido Wabnitz Yvonne Samstag Institute of Immunology Section Molecular ImmunologyHeidelberg UniversityIm Neuenheimer Feld 30569120 HeidelbergGermany Institute of Human Genetics Department of Human Molecular Geneticsand nCounter Core FacilityHeidelberg UniversityIm Neuenheimer Feld 36669120 HeidelbergGermany Department of dermatology Heidelberg UniversityIm Neuenheimer Feld 44069120 HeidelbergGermany

The interplay between keratinocytes and immune cells,especially T cells,plays an important role in the pathogenesis of chronic inflammatory skin *** psoriasis,keratinocytes attract T cells by releasing chemokines,while skin-infiltrating selfreactive T cells secrete proinflammatory cytokines,e.g.,IFN γand IL-17A,that cause epidermal ***,in chronic graftversus-host disease,allogenic IFN γ-producing Th1/Tc1 and IL-17-producing Th17/Tc17 cells are recruited by keratinocyte-derived chemokines and accumulate in the ***,whether keratinocytes act as nonprofessional antigen-presenting cells to directly activate naive human T cells in the epidermis remains ***,we demonstrate that under proinflammatory conditions,primary human keratinocytes indeed activate naive human T *** activation required cell contact and costimulatory signaling via CD58/CD2 and CD54/*** T cells costimulated by keratinocytes selectively differentiated into Th1 and Th17 *** particular,keratinocyte-initiated Th1 differentiation was dependent on costimulation through CD58/*** latter molecule initiated STAT1 signaling and IFN γproduction in T *** of T cells by keratinocytes resulting in Th1 and Th17 differentiation represents a new explanation for the local enrichment of Th1 and Th17 cells in the skin of patients with a chronic inflammatory skin ***,local interference with T cell–keratinocyte interactions may represent a novel strategy for the treatment of Th1 and Th17 cell-driven skin diseases.

关键词： keratinocytes inflammatory skin diseases psoriasis human T cells costimulation CD2 LFA-1 nonprofessional antigenpresenting cells Th1 cells Th17 cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

涂挂法电磁改性水泥基复合材料的吸波性能

华南理工大学学报（自然科学版） 2013年第2期41卷 135-140页

作者：国爱丽高日巴恒静北京交通大学土木建筑工程学院北京100044 哈尔滨工业大学土木工程学院黑龙江哈尔滨150090

为了获得具有吸波性能的水泥基复合材料,首先,采用涂挂法对闭孔珍珠岩和粉煤灰漂珠表面进行电磁改性.然后,通过测量各改性珍珠岩和粉煤灰漂珠与水泥基材料复合后材料的电磁波反射率,获得了吸波效果稳定的涂挂材料比例.最后,对比研究了... 详细信息

为了获得具有吸波性能的水泥基复合材料,首先,采用涂挂法对闭孔珍珠岩和粉煤灰漂珠表面进行电磁改性.然后,通过测量各改性珍珠岩和粉煤灰漂珠与水泥基材料复合后材料的电磁波反射率,获得了吸波效果稳定的涂挂材料比例.最后,对比研究了改性珍珠岩水泥基复合材料和石墨(或铁氧体)复合水泥基材料在S～C波段和X～Ku波段的电磁波反射率,并通过扫描电镜观测改性珍珠岩的微观结构.结果表明:石墨和铁氧体在连续釉化面与特殊蜂窝结构相间的珍珠岩颗粒表面分布均匀,形成有效谐振腔吸波体;涂挂法改性闭孔珍珠岩能有效提高水泥基材料的吸波性能,拓宽-10dB带宽.

关键词：水泥基复合材料涂挂法电磁改性吸波性能闭孔珍珠岩粉煤灰漂珠

The Proportional Hazards Model for Multiple Type Recurrent Gap Times

在线全文

学校读者我要写书评

暂无评论

Acta Mathematicae Applicatae Sinica 2016年第1期32卷 221-230页

作者： Ji-cai LIU Huan-bin LIU ri-quan ZHANG Department of Statistics East China Normal UniversityShanghai 200241China College of Mathematics and Computer Science Huanggang Normal University Huangzhou 438000China Department of Mathematics Shanxi Datong UniversityDatong 037009China

Recurrent events data and gap times between recurrent events are frequently encountered in many clinical and observational studies,and often more than one type of recurrent events is of *** this paper,we consider a proportional hazards model for multiple type recurrent gap times data to assess the effect of covaxiates on the censored event processes of *** estimating equation approach is used to obtain the estimators of regression coefficients and baseline cumulative hazard *** examine asymptotic properties of the proposed *** sample properties of these estimators are demonstrated by simulations.

关键词： proportional hazards model estimating equation multiple type recurrent events gap times semiparametric inference