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P08 Comparing study in self-motivation learning： PBL vs LBL

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中国药理通讯 2006年第2期23卷 18-19页

作者： HG NIE JQ CAI MJ WEI ZG SONG WB JIN JM LI XS YU bz sun department of pharmacology medical education research center China Medical UniversityLN Shenyang 110001

Evaluation of critical thinking skills in pharmacological PBL teaching

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Evaluation of critical thinking skills in pharmacological PB...

Satellite Meeting on Pharmacological Teaching & The 15th World Congress of Pharmacology

作者： Cai JQ Nie HG Yu XS sun bz (School of pharmaceutical science medical education research center China Medical University LN Shenyang 10001 P.R. China)

＜正＞OBJECTIVE: Critical thinking is regarded as purposeful, self-regulatory judgment, which is a composite of skills linked to problem-based learning （PBL）. Because rigorous evaluation of critical thinking had not been formally undertaken, the purpose of this study was to evaluate how the PBL in pharmacology was developing students’ critical thinking skills. METHOD: 3rd year medical students were initially randomized to participate in a PBL （n =30）, or a lecture-based learning （LBL, n =30） course in basic pharmacology. Data was collected quantitatively according to the modified CTDI-CV （California critical thinking disposition inventory-Chinese version） over a ten-hour period. RESULTS: The modified CTDI-CV score indicated that students using PBL teaching method scored overall higher than those using LBL mode （P＜0.001）, especially at truth seeking, open mindedness, analyticity, systematicity, inquisitiveness. CONCLUSION: The modified CTDI-CV is not only useful for the students to think through their appearance in critical thinking, but the teachers to evaluate the students’ critical thinking skills which will be very beneficial to the students by enhancing the practice according to their results.

关键词： critical thinking problem-based learning pharmacology medical education

来源： cnki会议评论

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广义KDV方程的显示行波解

四川师范大学学报（自然科学版） 2001年第4期24卷 339-341页

作者：孙峪怀四川师范大学数学系四川成都610066

非线性演化方程 ,特别是广义KDV方程因其丰富的数学物理内含而备受人们关注 ,其精确解的研究在理论和应用上都有重要的意义 .求出了广义KDV方程的显示精确解 ,同时给出了解成立的条件。

关键词：非线性演化方程行波解精确解孤立波广义KDV方程非线性偏微分方程

Interface effect on the giant magnetoresistance for different magnetic multilayers systems

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Chinese Science Bulletin 1997年第9期42卷 729-733页

作者： Zhang, LY sun, H Li, bz Pu, FK Institute of Physics Chinese Academy of Sciences Beijing China State Key Laboratory of Molecular Reaction Dynamics Institute of Chemistry Chinese Academy of Sciences Beijing China

THE giant magnetoresistance(GMR)effect in magnetic multilayer has been the subject of in-tense investigation since its *** theories,including semiclassical theoryand quantum theory,have been developed to deal with the... 详细信息

关键词： magnetic multilayer interface effect giant magnetoresistance Anderson model.

黄芪保心汤对实验性心肌缺血大鼠心肌组织MDA、SOD水平及心肌组织形态学的影响

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上海中医药大学学报 2000年第2期14卷 38-40页

作者：孙平龙尚云卫新国李小宁朱晓梅卫洪昌严世芸上海中医药大学上海200032 上海市南汇县光明中医院上海201300

探讨黄芪保心汤对实验性急性心肌缺血大鼠心肌组织丙二醛(MDA)、超氧化物歧化酶 (SOD)水平及心肌细胞形态学的影响。 5 6只大白鼠随机分为假手术组、模型对照组、黄芪保心汤组、复方丹参滴丸组 4组 ,测定并比较各组心肌MDA、SOD水平及... 详细信息

探讨黄芪保心汤对实验性急性心肌缺血大鼠心肌组织丙二醛(MDA)、超氧化物歧化酶 (SOD)水平及心肌细胞形态学的影响。 5 6只大白鼠随机分为假手术组、模型对照组、黄芪保心汤组、复方丹参滴丸组 4组 ,测定并比较各组心肌MDA、SOD水平及观察组织形态学改变。结果 :黄芪保心汤组与模型对照组比较 ,能显著降低心肌组织MDA含量 (P 0 0 5 ) ;黄芪保心汤组、复方丹参滴丸组与模型组比较 ,心肌组织SOD水平均显著升高 (P <0 0 5 )。光学及电子显微镜下观察 ,黄芪保心汤组和复方丹参滴丸组无明显的充血水肿 ,线立体结构保护完整。提示以益气活血祛痰化浊为主的黄芪保心汤能有效提高缺血心肌的抗氧化能力 ,保护心肌缺血损伤。

关键词：黄芪保心汤丙二醛中药药理丙二醛 SOD

Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bzIP28 in Arabidopsis

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Science China(Life Sciences) 2015年第3期58卷 270-275页

作者： sun Le ZHANG Shuang-Shuang LU sun-Jie LIU Jian-Xiang State Key Laboratory of Genetic Engineering Institute of Plant Biology School of Life Sciences Fudan University

Many sources of stress cause accumulation of unfolded or misfolded proteins in endoplasmic reticulum(ER), which elicits the unfolded protein response(UPR) to either promote cell survival or programmed cell death depending on different developmental context or stress severity. The Arabidopsis membrane-associated transcription factor, b ZIP28, is the functional equivalent of mammalian ATF6, which relocates from the ER to the Golgi where it is proteolytically processed and released from the membrane to the nucleus to mediate the UPR. Although the canonical site-1 protease(S1P) cleavage site on the ER lumen-facing domain is well conserved between b ZIP28 and ATF6, the importance of S1 P cleavage on b ZIP28 has not been experimentally demonstrated. Here we provide genetic evidence that the RRIL573 site, but not the RVLM373 site, on the lumen-facing domain of bz IP28 is critical for the biological function of b ZIP28 under ER stress condition. Further biochemistry and cell biology studies demonstrated that the RRIL573 site, but not the RVLM373 site, is required for proteolytic processing and nuclear relocation of b ZIP28 in response to ER stress. Our results reveal that S1 P cleavage site plays a pivotal role in activation and function of b ZIP28 during UPR in plants.

关键词： membrane-associated transcription factor ER stress unfolded protein response bz IP28 S1P S2P

A Novel laser scanning method for metallization of alumina substrate by copper

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Rare Metals 2023年第3期42卷 844-852页

作者： Yu Hui Zhao-Lin Na Bo-Ming sun Xu-Dong sun Jia-Lin Chen Liaoning Engineering Laboratory of Special Optical Functional Crystals College of Environmental and Chemical EngineeringDalian University Department of Chemistry Imperial College LondonLondon W120BZUK Institute of Ceramics and Powder Metallurgy School of Materials Science and EngineeringNortheastern UniversityShenyang 110819China State Key Laboratory of Advanced Technologies for Comprehensive Utilization of Platinum Metals Kunming Institute of Precious MetalsKunming 650106China

A laser scanning method was developed to metalize the surface of alumina substrates with *** modeling of the heating and cooling rates of the samples during the laser scanning process indicates that the metallization process involves the rapid melting and solidification of Al_(2)O_(3) and Cu and the evaporation and deposition of part of the *** surface of the metalized alumina substrate was composed of copper spheres(~60μm in diameter)embedded into the alumina substrate and a thin layer of CuAlO_(2).

关键词： solidification copper laser

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南社及南社研究

山东大学学报(哲学社会科学版) 2000年第6期 10-15页

作者：孙之梅山东大学文学院!山东济南250100

在民族主义旗帜下聚集到一起的南社 ,开创了一种民族民主革命的文学 ,它从国粹派“复兴古学”的理论获得学术支援 ,并把这一理论落实到发抉复社几社的文化精神、诗学传统和抗清的志节上。“几复风流”适应了排满革命的需要 ,也是区域性... 详细信息

在民族主义旗帜下聚集到一起的南社 ,开创了一种民族民主革命的文学 ,它从国粹派“复兴古学”的理论获得学术支援 ,并把这一理论落实到发抉复社几社的文化精神、诗学传统和抗清的志节上。“几复风流”适应了排满革命的需要 ,也是区域性文化资源在近代的又一次激活。南社历时十数年 ,大致分为四个时期。南社的研究现状需在研究队伍和研究观念上进行改变

关键词：南社几社复社分期研究

The Contribution of Mesoscale Convective Systems to Intense Hourly Precipitation Events during the Warm Seasons over Central East China

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Advances in Atmospheric Sciences 2016年第11期33卷 1233-1239页

作者： Zhiwei HE Qinghong ZHANG Jun sun Laboratory for Climate and Ocean-Atmosphere Studies Department of Atmospheric and Oceanic SciencesSchool of PhysicsPeking University National Meteorological Center China Meteorological Administration

Central East China is an area where both intense hourly precipitation（IHP） events and mesoscale convection systems（MCSs） occur frequently in the warm seasons. Based on mosaics of composite Doppler radar reflectivity and hourly precipitation data during the warm seasons（May to September） from 1 July 2007 to 30 June 2011, the contribution of MCSs to IHP events exceeding 20 mm h^-1 over central East China was evaluated. An MCS was defined as a continuous or quasicontinuous band of 40d bz reflectivity that extended for at least 100 km in at least one direction and lasted for at least 3h. It was found that the contribution of MCSs to IHP events was 45% on average over central East China. The largest contribution,more than 80%, was observed along the lower reaches of the Yellow River and in the Yangtze River–Huaihe River *** regions were the source regions of MCSs, or along the frequent tracks of MCSs. There were two daily peaks in the numbers of IHP events： one in the late afternoon and one in the early morning. These peaks were more pronounced in July than in other months. MCSs contributed more to the early-morning IHP event peaks than to the late-afternoon peaks. The contributions of MCSs to IHP events with different intensities exhibited no significant difference, which fluctuated around 50% on average over central East China.

关键词： afternoon morning reflectivity Precipitation contributions Yangtze convection mesoscale Events exceeding