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以补治秘对脑肠肽影响的研究进展

辽宁中医杂志 2024年第3期51卷 213-217页

作者：吴博谦张虹玺辽宁中医药大学辽宁沈阳110847 哈尔滨市中医医院黑龙江哈尔滨150010 辽宁中医药大学附属三院辽宁沈阳110003

便秘是一种常见的临床病症,其病程较长难以治愈。慢性便秘多属虚性或因虚致实,中医学治疗虚性便秘有其独特的优势。近年来随着脑肠轴研究的深入使中医疗法调整脑肠肽治疗便秘的临床实践与实验研究取得较大的发展,文章通过近年来医家学... 详细信息

便秘是一种常见的临床病症,其病程较长难以治愈。慢性便秘多属虚性或因虚致实,中医学治疗虚性便秘有其独特的优势。近年来随着脑肠轴研究的深入使中医疗法调整脑肠肽治疗便秘的临床实践与实验研究取得较大的发展,文章通过近年来医家学者通过以补治秘的中药方剂、中药化学成分、作用机理和针灸推拿等疗法治疗虚性便秘过程中对脑肠肽的影响加以综述。

关键词：中医药脑肠肽 5-羟色胺便秘

基于GNSS/INS的列车定位风险评估方法

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西南交通大学学报 2020年第6期55卷 1191-1198,F0002页

作者：吴波前蔡伯根陆德彪王剑北京交通大学电子信息工程学院北京100044 北京交通大学轨道交通控制与安全国家重点实验室北京100044 北京市轨道交通电磁兼容与卫星导航工程技术研究中心北京100044

全球卫星导航系统(global navigation satellite system,GNSS)应用于列车运行控制系统位置服务时,需对其进行风险评估,以确保其满足安全相关的需求.为此,首先建立一种基于卫星导航系统与惯导系统(inertial navigation system,INS)融合... 详细信息

全球卫星导航系统(global navigation satellite system,GNSS)应用于列车运行控制系统位置服务时,需对其进行风险评估,以确保其满足安全相关的需求.为此,首先建立一种基于卫星导航系统与惯导系统(inertial navigation system,INS)融合的列车定位单元结构,通过分析传感器融合数据对故障进行检测及识别,并计算水平保护距离,结合水平位置误差、水平告警门限、告警时间等指标参数,对列车定位单元的工作状态进行识别;其次在此基础上分析由危险状态生成的风险事件,并计算列车定位单元危险侧失效率及故障概率;最后结合现场试验数据对所提出的风险评估方法进行测试验证.验证结果表明:若误警率、漏检率均为1×10^−7/h,水平告警门限为20 m,定位单元在相对开阔环境下的故障率为9.14×10^−7/h,受限环境下的故障率为1.52×10^−4/h;若运行线路对风险指标参数需求降低,则误警率、漏检率及水平告警门限也会增大,受限环境下的定位单元故障率也随之降低,在误警率、漏检率均为1×10^−5/h,水平告警门限为100 m时,计算获得的受限环境下定位单元故障率为0.因此,在对定位单元进行风险评估时需考虑不同线路对指标参数的需求.

关键词：列车定位全球卫星导航系统多传感器融合风险评估完好性

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中医药治疗便秘对肠道菌群影响的研究进展

中华中医药学刊 2023年第6期41卷 115-122页

作者：吴博谦张虹玺辽宁中医药大学辽宁沈阳110847 哈尔滨市中医医院黑龙江哈尔滨150010 辽宁中医药大学附属第三医院辽宁沈阳110003

便秘是多种因素导致以排便困难为主要表现的常见疾病,传统中医学(traditional Chinese medicine,TCM)治疗慢性便秘有其独特的优势。肠道微生态学与肠道生理和病理密切相关,近年来随着肠道菌群深入研究和新型检测技术的应用使中医药疗法... 详细信息

便秘是多种因素导致以排便困难为主要表现的常见疾病,传统中医学(traditional Chinese medicine,TCM)治疗慢性便秘有其独特的优势。肠道微生态学与肠道生理和病理密切相关,近年来随着肠道菌群深入研究和新型检测技术的应用使中医药疗法调整肠道菌群治疗便秘的临床实践与实验研究取得较大的发展,通过关于中药复方、中成药、单药对便秘宿主肠道菌群影响的临床观察、机制研究和活性成分药理作用等进展进行综述。

关键词：中医药肠道菌群便秘

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Construction of Oryza sativa genome contigs by fingerprint strategy

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Cell Research 1995年第2期5卷 263-271页

作者： TAO QUANZHOU YUEMIN QIAN HAIYING ZHAO SHULIANG YU LONGFANG QIU boqian wu JIA ZHU DI YU XIAOHUI LIU GUOFAN HONG(National Center for Gene Research, Chinese Academy of Sciences, Shanghai 200233, China.)(Shanghai Institute of Biochemistry, Chinese Acad Shanghai Institute of Biochemistry Chinese Academy of Sciences Shanghai 200031 China.

We described the construction of BAC contigs of the genome of a indica variety of Oryza sativa, Guang Lu Ai *** entire representative (sixfold coverage of rice chromosomes) and genetically stable BAC library of rice genome constructed in this lab has been systematically analysed by restriction enzyme fragmentation and polyacrylamide gel electrophoresis. And all the images thus obtained were subject to image-processing, which consisted of preliminary location of bands, cooperative tracking of lanesby correlation of adjacent bands, a precise densitometric pass, alignment at the marker bands with the standard,optional interactive editing, and normalization of the accepted bands. The contigs were generated based on the Computer Software specially designed for genome map ping. The number of contigs with 600 kb in length on average was 464; of contigs with 1000 kb in length on average was 107; of contigs with 1500 kb in length on average was 23. Therefore, all the contigs we have obtained amounted up to 420 megabases in length. Considering the size of rice genome (430 megabased), the contigs generated in this lab have covered nearly 98% of the rice genome. We are now in the process of mapping the contigs to chromosomes.

关键词： Contig genome indica oryza sativa BAC

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基于神经网络的空气源热泵除霜诊断模型

暖通空调 2006年第6期36卷 100-103页

作者：曹亮胡平放吴伯谦华中科技大学

针对空气源热泵的除霜问题,利用人工神经网络在故障诊断方面的优势建立了一种简单的除霜诊断模型,提出了一种基于人工神经网络的除霜诊断方法。结合一个实例进行了分析,结果表明该诊断方法是切实可行的。

关键词：人工神经网络故障诊断空气源热泵除霜

Ballistic performances of the hourglass lattice sandwich structures under high-velocity fragments

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Defence Technology（防务技术） 2024年第1期31卷 312-325页

作者： He-xiang wu Jia Qu Lin-zhi wu Key Laboratory of Advanced Ship Materials and Mechanics College of Aerospace and Civil EngineeringHarbin Engineering UniversityHarbin150001China School of Civil Engineering Northeast Forestry UniversityHarbin150040China

In this paper,the numerical simulation method is used to study the ballistic performances of hourglass lattice sandwich structures with the same mass under the vertical incidence of *** is paid to elucidating the influences of rod cross-section dimensions,structure height,structure layer,and rod inclination angle on the deformation mode,ballistic performances,and ability to change the ballistic direction of *** results show that the ballistic performances of hourglass lattice sandwich structures are mainly affected by their structural *** this respect,structural parameters optimization of the hourglass lattice sandwich structures enable one to effectively improve their ballistic limit velocity and,consequently,ballistic performances.

关键词： Hourglass lattice sandwich structures Ballistic performances high-velocity Finite element analysis

Resilience-incorporated seismic risk assessment of precast concrete frames with“dry”connections

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 403-425页

作者： wu Chenhao Tang Yuchuan Cao Xuyang wu Gang Key Laboratory of Concrete and Prestressed Concrete Structures of the Ministry of Education Nanjing 211102China Department of Civil and Environmental Engineering University of CaliforniaLos AngelesCA 90095USA School of Civil Engineering Southeast UniversityNanjing 211102China College of Civil and Transportation Engineering Hohai UniversityNanjing 210024China

A resilience-incorporated risk assessment framework is proposed and demonstrated in this study to manifest the advantageous seismic resilience of precast concrete frame(PCF)structures with“dry”connections in terms of their low damage and rapid *** framework integrates various uncertainties in the seismic hazard,fragility,capacity,demand,loss functions,and post-earthquake *** this study,the PCF structures are distinguished from ordinary reinforced concrete frame(RCF)structures by characterizing multiple limit states for the PCF based on its unique damage ***,probabilistic story-wise pushover analyses are performed to yield story-wise capacities for the predefined limit *** the seismic resilience analysis,a step-wise recovery model is proposed to idealize the functionality recovery process,with separate considerations of the repair and non-repair *** recovery model leverages the economic loss and downtime to delineate the stochastic post-earthquake recovery curves for the resilience loss *** such,contingencies in the probabilistic post-earthquake repairs are incorporated and the empirical judgments on the recovery parameters are largely *** proposed framework is demonstrated through a comparative study between two“dry”connected PCFs and one RCF designed as alternative structural systems for a prototype *** results from the risk quantification indicate that the PCFs show reduced loss hazards and lower expected losses relative to the ***,the PCF equipped with energy dissipation devices at the“dry”connections largely reduces the expected economic loss,downtime,and resilience loss by 29%,56%,and 60%,respectively,compared to the RCF.

关键词： precast concrete frame non-emulative precast system seismic resilience seismic risk functional recovery

New findings on the influence of El Nino events on tropical cyclone formation

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Science China Earth Sciences 2024年第3期67卷 892-893页

作者： Liguang wu Department of Atmospheric and Oceanic Sciences Institute of Atmospheric SciencesFudan UniversityShanghai 200438China

Tropical cyclones typically form over warm tropical and subtropical ocean surfaces, as their formation and intensification rely primarily on the energy provided by the ocean. Pioneering research by Gray (1968) revealed that the formation of tropical cyclones requires the sea surface temperature (SST) to be no less than 26.5℃. Consequently, SST is commonly recognized as a crucial parameter among the environmental factors influencing tropical cyclone formation(Gray, 1979;Emanuel and Nolan, 2004).

关键词： tropical cyclone ocean

Two-dimensional semiconductor heterostructures for photocatalytic CO_(2)conversion

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Science China Chemistry 2024年第8期67卷 2434-2447页

作者： Yang wu Mingyu wu Yongfu Sun Yi Xie Hefei National Research Center for Physical Sciences at Microscale University of Science and Technology of ChinaHefei 230026China

The CO_(2)reduction into carbon-contained fuel via solar energy offers the powerful tools to realize the zero-emission carbon *** to the intriguing features of the two-dimensional(2D)heterostructures,it is susceptible to modulate the electronic structure as well as the surface geometry for optimizing the photocatalytic CO_(2)*** this perspective,we surveyed the fundamental insights of 2D semiconductor heterostructures,involving the fabrication strategies and classification of the 2D semiconductor ***,we have detailly discussed the overview of 2D semiconductor heterostructure for optimizing CO_(2)photocatalytic influenced factors,including the solar energy utilization,photogenerated carriers separation,and redox reaction ***,we showed the significant advantages of 2D heterostructures in elevating CO_(2)photoreduction performance,focusing on activity,selectivity and *** analyzing the limitations and developments,we ended by putting forward insights into the further researches about the CO_(2)photocatalysts and reactor design,even industrial applications.

关键词： two-dimensional semiconductor heterostructures photocatalysis CO_(2)conversion