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Maternal Group b Streptococcus Infection Correlates Inversely With Preeclampsia in Pregnant African American Women

Maternal-Fetal Medicine 2024年第1期6卷 23-28页

作者： Keun Soo Kwon Tzu Hsuan Cheng Simone A。Reynolds Jordan Zhou Huchong Cai Sharon lee Ivan Velickovic Mudar Dalloul David Wlody Ming Zhang Department of Anesthesiology State University of New York-Downstate Health Sciences UniversityNew York 11203USA Department of Epidemiology and biostatistics School of Public HealthState University of New York-Downstate Health Sciences UniversityNew York 11203USA Department of Obstetrics and Gynecology State University of New York-Downstate Health Sciences UniversityNew York 11203USA

Objective:To determine whether an association exists between group b Streptococcus(GbS)colonization and preeclampsia among pregnant black ***:This retrospective cross-sectional study involved black women who gave birth at State University of New york Downstate Hospital between January 2010 and December *** were collected from the Obstetric Department,including delivery date,time,mode of delivery,age of the mother,weeks of gestation at delivery,and antepartum *** GbS test results were originally determined using the eSwab transport *** was defined based on the American College of Obstetricians and Gynecologists criteria for the periods 2010–2012 and 2013–*** primary outcome was whether GbS was associated with the outcome of preeclampsia in the population of black ***,including smoking status,gestational age,parity,body mass index,maternal age,and presence of herpes simplex virus(HSV)and human immunodeficiency virus(HIV)were examined as potential ***-squared test and logistic regression model were used,presenting odds ratios with 95%confidence intervals(Pyzed with SAS on Demand for Academics(SAS Institute,Inc.,Ny).Results:Among the 8,019 black women included in this study,GbS-positive women(n=977)had a 53%reduction in the likelihood of being diagnosed with preeclampsia compared to GbS-negative women(adjusted odds ratio,0.47;95%confidence interval,0.32–0.70).We did not find evidence of differences in the distribution of smoking habits(P=0.783)or maternal age(P=0.107)between GbS-positive and GbS-negative ***,the GbS-positive women tended to be less likely to have a preterm delivery(9.62%(94/977)vs.24.24%(1707/7042),Py to be nulliparous(33.37%(326/977)vs.37.87%(2667/7042),P=0.006),and less likely to be obese(51.38%(502/977)vs.55.30%(3894/7042),PbS-negative *** contrast,GbS-positive women were more likely to have a comorbid infecti

关键词： Pregnancy outcome Preeclampsia GbS colonization African American Afro-Caribbean

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Present Status of the KSTAR Superconducting Magnet System Development

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Plasma Science and Technology 2004年第5期6卷 2445-2450页

作者： Keeman Kim H.K.Park K.R.Park b.S.Lim S.I.lee M.K.Kim y.Chu W.H.Chung S.H.baek J.y.Cho H.yonekawa A.Chertovskikh y.b.Chang J.S.Kim C.S.Kim D.J.Kim N.H.Song K.P.Kim y.J.Song I.S.Woo W.S.Han D.K.lee y.K.Oh K.W.Cho J.S.Park G.S.lee H.J.lee T.K.Ko S.J.lee National NationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalNationalKorea Atomic Energy Research InstituteDaejeonRepublic of KoreaYonsei UniversitySeoulRepublic of KoreaYonsei UniversitySeoulRepublic of Korea Fusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science InstituteDaejeonRepublic of KoreaFusion R&D CenterKorea Basic Science

The mission of Korea Superconducting Tokamak Advanced Research (KSTAR)project is to develop an advanced steady-state superconducting tokamak for establishing a scientificand technological basis for an attractive fusion reactor. because one of the KSTAR mission is toachieve a steady-state operation, the use of superconducting coils is an obvious choice for themagnet system. The KSTAR superconducting magnet system consists of 16 Toroidal Field (TF) coils and14 Poloidal Field (PF) coils. Internally-cooled Cable-In-Conduit Conductors (CICC) are put into usein both the TF and PF coil systems. The TF coil system provides a field of 3.5 T at the plasmacenter and the PF coil system is able to provide a flux swing of 17 V-sec. The major achievement inKSTAR magnet-system development includes the development of CICC, the development of a full-size TFmodel coil, the development of a coil system for background magnetic-field generation , theconstruction of a large-scale superconducting magnet and CICC test facility. TF and PF coils are inthe stage of fabrication to pave the way for the scheduled completion of KSTAR by the end of 2006.

关键词： superconducting magnet KSTAR CICC

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Current Status of the KSTAR Engineering

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Plasma Science and Technology 2004年第1期6卷 2159-2165页

作者： J.S.bak K.Kim C.H.Choi y.K.Oh b.C.Kim N.I.Her H.L.yang G.S.lee the KSTAR Team Korea basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 KoreaKorea Basic Science Institute 52 Yeoeun-Dong Yusung-Ku Daejeon 305-333 Korea

As there is substantial progress in the KSTAR tokamak engineering, all themajor structures and sub-systems are under fabrication and in procurement phase. The vacuum vessel,port, cryostat cylinder, lid, and bellows are being rigorously fabricated in the factory. The lowerpart of the KSTAR such as cryostat base and gravity support has been almost finished in itsfabrication. There are also great progresses and significant results in manufacturing of thesuperconducting magnet, including four Toroidal Field (TF) coils, lower and upper PF7 coils whichare the largest Poloidal Field (PF) coils. The TFOO coil, which has been made for test and back-upof the TF magnet system, was successfully tested in the cool-down and current charging. As thefabrications and procurements of major structures have been actively proceeded, assemb.y works werealso launched from Aug. 2003. More detailed description on these status, results, and plans will bedescribed in this paper.

关键词： KSTAR tokamak vacuum vessel magnet cryostat tokamak assemb.y

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Projectile Fragmentation in ^(20)Ne-^(165)Ho Reaction at 45 MeV/u

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Chinese journal of nuclear physics 1995年第3期17卷 228-233页

作者： G.X.Dai J.b.Natowitz R.Wada K.Hagel Q.Z.Luo Z.y.He J.blackadar S.lee J.T.Li y.N.Lou D.Utley b.Xiao Institute of Modern Physics Chinese Academy of SciencesP.O.Box 31Lanzhou 7300002 Cylotron Institute and Physics DepartmentTexas A & M UniversityCollege StationTexas 77843 Cylotron Institute and Physics Department Texas A & M UniversityCollege StationTexas 77843 Institute of Modern Physics Chinese Academy of SciencesP.O.Box 31Lanzhou 7300002

At 45 MeV/u an experiment on fragmentation of projectile(20Ne)on 165Ho was *** average reduced width σ0 of 84.3±6.6 MeV/c was obtained by separating the break=up of all com-plex fragments of 20Ne from the evaporatio... 详细信息

At 45 MeV/u an experiment on fragmentation of projectile(20Ne)on 165Ho was *** average reduced width σb>0b> of 84.3±6.6 MeV/c was obtained by separating the break=up of all com-plex fragments of 20Ne from the evaporation part of compound nucleus in momentum spectra.

关键词： Projectile fragmentation Reduced width of Fermi momentum 20Ne+165Ho reaction

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基于三通道CNN-GSAM-LSTFEM网络的雷达人体切向动作识别

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雷达科学与技术 2024年第2期22卷 135-144,154页

作者：屈乐乐祝诗卉沈阳航空航天大学电子信息工程学院辽宁沈阳110136

为了提高干涉雷达对人体切向动作的识别性能,本文提出一种基于三通道CNN-GSAM-LSTFEM网络的人体切向动作识别方法。首先利用一发二收的调频连续波(FMCW)雷达搭建干涉雷达平台采集人体切向动作回波数据,之后对每个接收通道的回波数据进... 详细信息

为了提高干涉雷达对人体切向动作的识别性能,本文提出一种基于三通道CNN-GSAM-LSTFEM网络的人体切向动作识别方法。首先利用一发二收的调频连续波(FMCW)雷达搭建干涉雷达平台采集人体切向动作回波数据,之后对每个接收通道的回波数据进行预处理,得到每个接收通道的多普勒时频图(DTFM)和双通道的干涉时频图(ITFM),然后将这3种时频图分别送入到3个并行的CNN-GSAM-LSTFEM网络进行训练,利用全局空间注意力模块(GSAM)和长短时特征提取模块(LSTFEM)增强卷积神经网络(CNN)的特征提取能力,最后将三通道提取的特征进行融合实现人体切向动作识别。实验结果表明,所提方法可有效提高人体切向动作的识别准确率,平均准确率高达98.77%。

关键词：人体动作识别干涉雷达注意力机制卷积神经网络特征融合

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Phase Formation and Magnetic Properties of Nanocomposite Nd-Fe-b Adjusted by Small Amount of Dy and Co

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Journal of Rare Earths 2004年第z2期22卷 89-94页

作者： T S Jang T W Lim H S Aum D H lee M b Kim Division of Materials and Chemical Engineering Sun Moon UniversityKorea Division of Materials and Chemical EngineeringSun Moon UniversityKorea Division of Mechanical EngineeringSun Moon University 100 Kalsan LiTangjung MyonAsan CityChoongnam 336-708Korea Division of Materials and Chemical EngineeringSun Moon UniversityKorea Division of Materials and Chemical EngineeringSun Moon UniversityKorea

In order to improve and stabilize the magnetic properties of nanocomposite Nd2Fe14b/α-Fe magnetic alloys by a compositional adjustment, small amount of Dy and/or Co was added to Nd9Fe84b7 alloys. DTA analysis on the amorphous of the alloys took place as the soft magnetic phases were crystallized, and then the hard magnetic Nd2Fe14b was precipitated from them. While α-Fe and a metastable 1:7 (TbCu7-type) phase were formed simultaneously in Dy and Co-free alloys, they were crystallized separately at different temperatures after Dy or Co was added. This phase separation occurred more clearly in the Dy-treated alloys and the other soft magnetic phase Fe3b was also stabilized by Dy and/or Co. The 1: 7 phase that was stabilized by Dy and/or Co was not eliminated at 700 ℃, decreasing magnetic properties of the alloys. It was eventually disappeared above 725 ℃, but Fe3b was not eliminated even at 750 ℃ when Dy was added more than 0.5 at% or Co was added more than 2.0 at%. Amount of Nd2Fe14b in the alloys tended to increase as Dy addition increased,whereas Co addition did not lead to any appreciable change in the ratio of α-Fe and Nd2Fe14b. Moreover, Dy addition apparently increased coercivity of an alloy while Co addition had a beneficial effect on remanence. The grains in the Dytreated alloys were usually finer than those in the Co-treated alloys. The grain size of both α-Fe and Nd2Fe14b in the alloys exhibiting mr ≥ 0.72 was in the range of 20 ～ 40 nm or even larger 50 nm, which is larger than the theoretical optimum size ( ～ 10 nm). Typical magnetic properties obtained from a Nd7.5Dy1.5Fe82.5Co1.5b7 alloy annealed for 12 min at 725 ℃were iHc=4.85 kOe, br= 11.32 kG, (bH)max = 15.73 MGOe, and mr=0.73.

关键词： nanocomposite Nd-Fe-b magnetic properties remanence coercivity

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Complement activation by phospholipids: the interplay of factor H and C1q

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Protein & Cell 2010年第11期1卷 1033-1049页

作者： lee Aun Tan bingbin yu Francis CJ Sim Uday Kishore Robert b Sim MRC Immunochemistry Unit Department of BiochemistryUniversity of OxfordSouth Parks RdOxford OX13QUUK Department of Pharmacology University of OxfordMansfield RoadOxford OX13QTUK Centre for Infection Immunity and Disease MechanismsBiosciencesSchool of Health Sciences and Social CareBrunel UniversityUxbridge UB83PH West LondonUK Present address Department of Immunology Faculty of MedicineImperial College LondonHammersmith HospitalDu Cane RoadLondon W120NNUK Present address School of Life Sciences and Engineering Biology BuildingTsinghua UniversityBeijing 100084China

Complement proteins in blood recognize charged *** anionic phospholipid(aPL)cardiolipin binds both complement proteins C1q and factor H.C1q is an activator of the complement classical pathway,while factor H is an inhibitor of the alternative *** examine opposing effects of C1q and factor H on complement activation by aPL,we surveyed C1q and factor H binding,and complement activation by aPL,either coated on microtitre plates or in *** C1q and factor H bound to all aPL tested,and competed directly with each other for *** the aPL activated the complement classical pathway,but negligib.y the alternative pathway,consistent with accepted roles of C1q and factor ***,in this system,factor H,by competing directly with C1q for binding to aPL,acts as a direct regulator of the complement classical *** regulatory mechanism is distinct from its action on the alternative *** of classical pathway activation by factor H was confirmed by measuring C4 activation by aPL in human sera in which the C1q:factor H molar ratio was adjusted over a wide *** factor H,which is regarded as a down-regulator only of the alternative pathway,has a distinct role in downregulating activation of the classical complement pathway by aPL.A factor H homologue,β2-glycoprotein-1,also strongly inhibits C1q binding to *** globular domains of C1q A,b and C chains bound aPL similarly to native C1q,confirming that C1q binds aPL via its globular heads.

关键词： complement regulation classical pathway C1q factor H anionic phospholipid

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Interactions of complement proteins C1q and factor H with lipid A and Escherichia coli:further evidence that factor H regulates the classical complement pathway

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Protein & Cell 2011年第4期2卷 320-332页

作者： lee Aun Tan Andrew C.yang Uday Kishore Robert b.Sim Medical Research Council Immunochemistry Unit Department of BiochemistryUniversity of OxfordSouth Parks RoadOxford OX13QUUK Present address:Department of Immunology Faculty of MedicineImperial College LondonHammersmith HospitalDu Cane RoadLondon W120NNUK St Peter’s College New Inn Hall St.Oxford OX12DLUK Present address:SUNy Downstate College of Medicine 450 Clarkson Avenue BrooklynNY 11203USA Weatherall Institute of Molecular Medicine John Radcliffe HospitalUniversity of OxfordHeadingtonOxford OX39DSUK Present address:Center for Infection Immunity and Disease MechanismsBiosciencesSchool of Health Sciences and Social CareBrunel UniversityUxbridge UB83PH West LondonUK Present address:Department of Pharmacology University of OxfordMansfield RoadOxford OX13QTUK

Proteins of the complement system are known to interact with many charged *** recently characterized binding of C1q and factor H to immobilized and liposomal anionic *** H inhibited C1q binding to anionic phospholipids,suggesting a role for factor H in regulating activation of the complement classical pathway by anionic *** extend this finding,we examined interactions of C1q and factor H with lipid A,a well-characterized activator of the classical *** report that C1q and factor H both bind to immobilized lipid A,lipid A liposomes and intact Escherichia coli *** H competes with C1q for binding to these ***,increasing the factor H:C1q molar ratio in serum diminished C4b fixation,indicating that factor H diminishes classical pathway *** recombinant forms of the Cterminal,globular heads of C1q A,b and C chains bound to lipid A and *** in a manner qualitatively similar to native C1q,confirming that C1q interacts with these targets via its globular head *** observations reinforce our proposal that factor H has an additional complement regulatory role of down-regulating classical pathway activation in response to certain *** is distinct from its role as an alternative pathway *** suggest that under physiological conditions,factor H may serve as a downregulator of bacterially-driven inflammatory responses,thereby finetuning and balancing the inflammatory response in infections with Gram-negative bacteria.

关键词： complement lipid A bacteria factor H C1q

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Novel Sources of aus Rice for Zinc Deficiency Tolerance Identified Through Association Analysis Using High-Density SNP Array

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Rice science 2018年第5期25卷 293-300页

作者： Jae-Sung lee Matthias WISSUWA Oscar b. ZAMORA Abdelbagi M. ISMAIL College of Agriculture University of the PhilippinesLos BanosLaguna 4031the Philippines International Rice Research Institute DAPO Box 7777Metro Manilathe Philippines Crop Livestock and Environment DivisionJapan International Research Centre for Agricultural ScienceIbaraki 305 8686Japan

Zinc （Zn） deficiency is a major soil constraint limiting rice crop growth and yield, yet the genetic control of tolerance mechanisms is still poorly understood. Here, we presented promising loci and candidate genes conferring tolerance to Zn deficiency and identified through association analysis using a 365 K single nucleotide polymorphism （SNP） marker array in a diverse aus （semi-wild type rice） panel. Tolerant accessions exhibited higher growth rate with relatively rare stress symptoms. Two loci on chromosomes 7 and 9 were strongly associated with plant vigor under Zn deficiency at a peak-stress stage. based on previous microarray data from the same experimental plots, we highlighted four candidate genes whose expressions were accompanied by significant genotype and/or environment effects under Zn deficiency. Network-gene ontology supported known tolerance mechanisms, such as ascorbic acid pathway, and also suggested the importance of photosynthesis genes to overcome Zn deficiency symptoms.

关键词： aus genome-wide association study Zinc deficiency rice

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Origin of Tornado-like vortices in a boundary layer

Origin of Tornado-like vortices in a boundary layer

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2003’全国流体力学青年研讨会

作者： y.P.SHI C.b.lee State Key Laboratory for Turbulence Research and Complex System Beijing 100871China State Key Laboratory for Turbulence Research and Complex System Beijing 100871China

＜正＞ This paper describes the origins of a tornado-like vortex in a boundary layer. Laboratory experiments and theoretical analysis were employed to investigate the dynamic processes related to the formation of the tornado-like vortex. The tornado-like vortex is generated by self-induction of a vortex ring in a boundary layer with the ring vortex produced by the thermal instabilities related to rising warm air interacting with cooler surroundings.

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