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Spectrum of venous thromboembolism in adult patients with ulcerative colitis in Pakistan:A single center retrospective study

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World Journal of Clinical Cases 2025年第6期13卷 9-13页

作者： Masood Muhammad Karim Hafsa Shaikh Faisal Wasim ismail Department of Medicine The Aga Khan University HospitalKarachi 74800Pakistan Department of General Surgery The Aga Khan University HospitalKarachi 74800Pakistan

BACKGROUND Patients with inflammatory bowel disease are at a 2-8-fold higher risk of deve-loping venous thromboembolism(VTE)as compared to the general *** the exact pathogenesis is unclear,the literature suggests that increased risk of thromboembolic events in such patients occurs as a result of increased coagulation factors,inflammatory cytokines,and reduction in anticoagulants leading to a prothrombotic *** To assess the prevalence,risk factors,management,and outcome of ulcerative colitis(UC)patients who develop *** This was a retrospective chart review done in The Gastroenterology Department of The Aga Khan University *** was collected from medical records for all patients admitted with a diagnosis of UC from January 2012 to December *** Seventy-four patients fulfilled the inclusion *** mean±SD of age at presentation of all UC patients was 45 years±10 years whereas for those who developed VTE,it was 47.6 years±14.7 *** and diabetes were the most common co-morbid seen among UC patients with a frequency of 17(22.9%)and 12(16.2%),respectively.A total of 5(6.7%)patients developed *** venous thrombosis was the most common thromboembolic phenomenon seen in 3(60%)*** the patients with UC and concomitant VTE were discharged home(5;100%).CONCLUSION The prevalence of VTE with UC in Pakistani patients corresponds with the international ***,multi-centric studies are required to further explore these results.

关键词： Deep venous thrombosis Inflammatory bowel disease Low-middle-income country Anticoagulation Protein C deficiency

Rising incidence of acute hepatitis A among adults and clinical characteristics in a tertiary care center of Pakistan

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World Journal of Virology 2025年第1期14卷 73-82页

作者： Yumna Shahid Amna Subhan Butt Iqra Jamali Faisal Wasim ismail Division of Gastroenterology Department of MedicineAga Khan University HospitalKarachi 74800Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan

BACKGROUND For decades,hepatitis A virus(HAV)has been a leading cause of acute hepatitis among children and was less prevalent among ***,recently a paradigm shift has been observed in the epidemiology of HAV,as evident by cases of acute hepatitis due to HAV among *** To estimate frequency of HAV in acute viral hepatitis and compare characteristics in HAV and hepatitis E virus(HEV)*** This was a trend analysis conducted at Aga Khan University Hospital Karachi(Sindh,Pakistan)from February 2024 to May *** aged 18 years and older diagnosed with acute viral hepatitis attributed to hepatotropic viruses in 2024 were *** compare the trend patients admitted with acute hepatitis during 2019-2023 were also *** regarding clinical and laboratory parameters were *** yearly trend of acute hepatitis due to HAV and HEV was analyzed,and comparative analysis was done between HAV and HEV cases among *** A total of 396 patients were found to have acute hepatitis during our study *** was diagnosed in 234 patients(59%)while 157 patients(39.6%)were found to have acute HEV ***,acute hepatitis B virus infection was identified in 3 patients(0.7%),whereas acute hepatitis C virus infection was found in 2(0.5%)cases of acute *** trends showed increasing occurrence of HAV infection among adults over last 5 *** patients with acute HAV were younger than patients with HEV(28 years±8 years vs 30 years±8 years;P<0.01).Higher levels of total bilirubin were seen in HEV infection,while higher levels of alanine transaminase were seen in HAV ***,a higher proportion of acute liver failure(ALF),coagulopathy,and mortality were observed in *** An increase in acute hepatitis A cases among adults shows less severity than hepatitis E,highlighting the need for better sanitation,hygiene,and adult hepatitis A vaccination programs.

关键词： Acute hepatitis Hepatitis A virus Hepatitis E virus Acute liver failure Hepatotropic virus Vaccination

Influence of alkaline treatment and fiber loading on the physical and mechanical properties of kenaf/polypropylene composites for variety of applications

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Progress in Natural Science:Materials International 2016年第6期26卷 657-664页

作者： Majid Niaz Akhtar Abu Bakar Sulong M.K.Fadzly Radzi N.F.ismail M.R.Raza Norhamidi Muhamad Muhammad azhar Khan Department of Physics COMSATS Institute of Information Technology Department of Mechanical and Materials Engineering Faculty of Engineering and Built EnvironmentUniversiti Kebangsaan Malaysia Department of Basic Sciences and Humanities Muhammad Nawaz Sharief University of Engineering and Technology(MNSUET) Department of Mechanical Engineering COMSATS Institute of Information Technology Department of Physics The Islamia University of Bahawalpur

Due to current trend and increasing interest towards natural based fiber products, Kenaf(Hibiscus cannabinus)fibers have been used for the developments of many products. Therefore, Kenaf fiber-reinforced composites have been widely used in engineering and industrial applications. The present work deals with the fabricating and characterization of untreated and treated kenaf/polypropylene(PP)-reinforced composites. Composites of PP reinforced with treated and untreated kenaf fibers were fabricated using the injection molding *** fiber loadings of 10, 20, 30, 40, 50 wt% treated and untreated kenaf composites were also prepared. Xray diffraction(XRD), scanning electron microscopy(SEM), Fourier transform infrared(FTIR) spectroscopy and thermo gravimetric analysis(TGA) were performed on the treated, untreated kenaf fibers and kenaf/PP composites. Moreover, the alkaline-treated kenaf composites exhibit better physical, morphological, and mechanical properties because of the compatibility of kenaf with PP. However, variations in tensile and flexural properties depend on treatment and kenaf fiber contents. The percentage increase in the mechanical properties of the treated kenaf/PP composites relative to that of PP was also measured. In addition, 40 wt%kenaf fiber loading resulted in higher mechanical properties. By contrast, kenaf/PP composite with 50% fiber loading was not successfully prepared because of improper mixing and the burning of kenaf fibers in the PP matrix. To conclude, 40% kenaf/PP composites with superior physical and mechanical properties may be used in variety of applications such as automotive, sports, construction, animal bedding, and mass production industries.

关键词： Kenaf composites Microstructures Physical properties Mechanical Testing Injection-molding

ANN-based empirical modelling of pile behaviour under static compressive loading

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Frontiers of Structural and Civil Engineering 2018年第4期12卷 594-608页

作者： Abdussamad ismail Department of Civil Engineering Bayero UniversityKanoNigeria

Artificial neural networks have been widely used over the past two decades to successfully develop empirical models for a variety of geotechnical problems. In this paper, an empirical model based on the product-unit neural network (PUNN) is developed to predict the load-deformation behaviour of piles based SPT values of the supporting soil. Other parameters used as inputs include particle grading, pile geometry, method of installation as well as the elastic modulus of the pile material. The model is trained using full-scale pile loading tests data retrieved from FHWA deep foundations database. From the results obtained, it is observed that the proposed model gives a better simulation of pile load-deformation curves compared to the Fleming’s hyperbolic model and t-z approach.

关键词： piles in compression load-deformation behaviour product-unit neural network

Estimating moment capacity of ferrocement members using self-evolving network

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Frontiers of Structural and Civil Engineering 2019年第4期13卷 926-936页

作者： Abdussamad ismail Department of Civil Engineering Bayero University Kano Kano State PMB 3011 Nigeria

In this paper, an empirical model based on self-evolving neural network is proposed for predicting the flexural behavior of ferrocement elements. The model is meant to serve as a simple but reliable tool for estimating the moment capacity of ferrocement members. The proposed model is trained and validated using experimental data obtained from the literature. The data consists of information regarding flexural tests on ferrocement specimens which include moment capacity and cross-sectional dimensions of specimens, concrete cube compressive strength, tensile strength and volume fraction of wire mesh. Comparisons of predictions of the proposed models with experimental data indicated that the models are capable of accurately estimating the moment capacity of ferrocement members. The proposed models also make better predictions compared to methods such as the plastic analysis method and the mechanism approach. Further comparisons with other data mining techniques including the back-propagation network, the adaptive spline, and the Kriging regression models indicated that the proposed models are superior in terms prediction accuracy despite being much simpler models. The performance of the proposed models was also found to be comparable to the GEP-based surrogate model.

关键词： ferrocement moment capacity self-evolving neural network

Numerical and Experimental Study of the Impact of Key Parameters on a PVT Air Collector:Mass Flow Rate and Duct Depth

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Journal of Thermal Science 2021年第5期30卷 1625-1642页

作者： ismail BAKLOUTI Zied DRISS National School of Engineers of Monastir University of Monastir5019MonastirTunisia Laboratory of Electromechanical Systems(LASEM) National School of Engineers of SfaxUniversity of Sfax3038SfaxTunisia

The PVT-air solar system simultaneously generates electrical and thermal ***,increasing the cost-effectiveness of the system requires an appropriate choice of key parameters such as mass flow rate and air channel *** this paper,a PVT-air kit of a single module with a 30°slope was used to measure photovoltaic electricity and air heating power in the city of Sfax,***,a computer method was implemented using the ANSYS Fluent 17.0 software and the MATLAB program to analyse the properties of the airflow and to characterise PVT-air yields under different mass flow rates and *** the comparison of numerical and experimental data,the numerical method was validated with a good ***,we have found that increasing of the airflow rate improves the thermal efficiency with a slight change on electrical ***,the reduction in depth shows an improvement on thermal efficiency and a negligible effect on electrical ***,we have presented the thermal and electrical performance of PVT-air as a function of the key parameters with the Hottel-Whillier-Bliss formulation.

关键词： solar energy PVT-air thermal experimental numerical performance

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Attitudes and understanding of complementary and alternative medicine in cancer care:An exploratory study of patients’perspectives in Karachi,Pakistan

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Asian Pacific Journal of Tropical Medicine 2023年第9期16卷 400-408页

作者： Shahlla Imam Muneeba Aijaz Wajiha Iffat Shazia Qasim Jamshed Nahlah Elkudssiah ismail Ganesh Sritheran Paneerselvam Khang Wen Goh Long Chiau Ming Halima Sadia Iqbal azhar Department of Pharmacognosy Faculty of Pharmacy and Pharmaceutical SciencesUniversity of KarachiSindh 75270Pakistan Department of Pharmacognosy Institute of Pharmaceutical SciencesJinnah Sindh Medical UniversityKarachiSindh 75510Pakistan Department of Pharmaceutics Dow College of PharmacyDow University of Health SciencesKarachiSindh 75270Pakistan Clinical Pharmacy and Practice Faculty of PharmacyUnivesiti Sultan Zainal Abidin(UNISZA)Besut22200TerengganuMalaysia Malaysian Academy of Pharmacy Puchong 47160SelangorMalaysia Clinical Pharmacy and Pharmacy Practice Unit Faculty of PharmacyAIMST University08100 BedongKedahMalaysia School of Pharmacy Taylor’s UniversitySunway CityMalaysia Faculty of Data Science and Information Technology INTI International University71800 NilaiMalaysia School of Medical and Life Sciences Sunway University47500 Sunway CityMalaysia Department of Pharmacy Practice Faculty of PharmacyJinnah Women UniversityKarachiPakistan

Objective:To evaluate the prevalence and types of complementary and alternative medicine(CAM)modalities among patients with cancer in Karachi,***:This descriptive cross-sectional study was conducted from March 2021 to December *** hundred patients with cancer were invited to participate in the *** databases,namely,Google scholar,Publons,EMBASE,PubMed,Chinese National Knowledge Infrastructure Database,and ResearchGate was used for questionnaire *** self-administered survey included questions on demographic characteristics,education level,socio-economic conditions and information about CAM therapies,prevalence,effectiveness,and common CAM *** analysis was conducted using SPSS software version ***:Out of the 500 invited patients,433(86.6%)successfully completed and returned the *** contrast to patients who were with younger,highly educated,professionally active,higher income,and had advanced cancer,time since diagnosis,type of treatment,cancer types and family history are significantly associated with CAM *** results showed that 59.8%of the participants were acquainted with complementary and/or alternative medicine and considered safe owing to its natural *** prevalence of CAM usage among cancer patients was 40.9%and the most widely used CAM modality was herbal medicine(27.7%)and dietary supplements(28.8%).Patients used CAM as a complementary therapy to improve the morphological parameter(28.2%),strengthen the immune system(6.8%),and to decrease the side effects of conventional treatment(18.1%).Most of the respondents get the information regarding CAM therapy from the electronic media(43.2%)and the family members(48%)rather than healthcare ***:Participants used CAM modalities along with the conventional health care *** multicentre studies should be conducted to provide information regarding the usage of CAM therapies and their eventual benefi

关键词： Alternative medicine Cancer patients Complementary medicine Cross-sectional study

Availability of seismic vulnerability index(K_g) in the assessment of building damage in Van, Eastern Turkey

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Earthquake Engineering and Engineering Vibration 2020年第1期19卷 189-204页

作者： ismail Akkaya Van Yüzüncü Yil University Engineering FacultyDepartment of Geophysical Engineering

The seismic vulnerability index(Kg) is a parameter that depends on the dynamic properties of soil. With this parameter, it is possible to evaluate the vulnerability of a point-based site under strong ground motion. Since it is related to the natural vibration period and amplification factor, the parameter can be calculated for both soil and structure. In this study, HVSR microtremor measurements are recorded at more than 200 points in the Van region to generate a seismic vulnerability index map. After generating the map, it is determined that the hazard potential and seismic vulnerability index is high at the sites close to Van Lake and at the densely populated city center. Damage information of the buildings investigated after the 2011 Van earthquakes(Mw = 7.1) are placed on the seismic vulnerability index map and it is realized that there may be a correlation between the damage and the seismic vulnerability index. There is a high correlation, approximately 80 percent, between the damage rate map based on the damaged building data and the K_g values. In addition, vulnerability indexes of buildings are calculated and the effect of local soil conditions and building properties on the damage levels are determined. From the results of this study and the site observations after the 2011 Van earthquakes, it is found that structural damage is not only structure-dependent but is also related to the dynamic behavior of soil layers and local soil conditions.

关键词： seismic vulnerability index building damage HVSR soil-structure interaction

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Quasi-periodic variations of low energy cosmic rays

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Science China(Technological Sciences) 2016年第4期59卷 547-557页

作者： KUDELA Karel SABBAH ismail IEP SAS Kosice Slovakia Department of Natural Sciences College of Health Sciencesthe Public Authority for Applied Education and TrainingKuwait

Cosmic rays(CR)play an important role in space weather-related *** temporal variability,both of a quasi-periodic character as well as an irregular one,has been studied from ground-based direct measurements,as well as from cosmogenic nuclides,over a long *** attempt to describe the current knowledge of selected quasi-periodicities in CR flux in the energy range above the atmospheric threshold,from direct *** power spectrum density(PSD)of the CR time series as measured by neutron monitors(NMs)and by muon detectors has a rather complicated *** with the shape(slope)of the PSD,knowledge of the contribution of quasi-periodic variations(q-per)to the CR signal is of importance for the modulation,as well as for checking the links of CR to space weather,and/or to space climate *** rotation of the Earth and solar rotation cause two types of mechanisms behind the certain q-per observed in secondary CR on the Earth’s *** activity and solar magnetic field cyclicities contribute to the q-per signals in CR if studied over a longer *** complexity of the spatial structure of the interplanetary magnetic field(IMF)and its evolution within the heliosphere,in addition to the changes in the geomagnetic field,cause variability in contributions of the q-per in *** spectra are useful tools for checking the fine structure of q-per and their temporal *** a long time NMs and muon telescopes provide information about q-per in CR.

关键词： cosmic rays periodicities neutron monitors muon detectors

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