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Particuology 2024年第1期84卷 249-260页

作者： Hassan M.Hmood Saba A.Gheni Safaa M.R.Ahmed Mudheher M.Ali Hamid Yonis Saleh mohammed H.mohammed awad e.moham.e. Marwan A.Mahomood Hiba R.mohammed Ahmed A.Hassan Adam Harvey North Refineries Company Ministry of OilIraq Chemical engineering Department Tikrit UniversityIraq Ministry of Oil Iraq AL-Hawija Technical Institute Northern Technical UniversityMoselIraq School of engineering Newcastle UniversityUK

To meet the rapidly increasing demand for energy and the dramatic depletion of conventional crude oil,it is imperative to utilize sour *** no coke being produced,oxidative desulfurization(ODS)of naphtha lowers its sulfur content and average molecular *** this article,we outline a method for heavy naphtha non-extractive ODS using a very stable *** technique involves the use of a solid catalyst with oxygen gas as the *** necessitated relatively high mixing intensities;hence a three-phase Oscillatory Baffled Reactor(OBR)was *** catalyst was based on the zeolite ZSM-5,prepared from natural kaolin by a series of delamination and activation steps and impregnated with Fe.A TiO2 nanolayer was applied,using the sol-gel method,to prevent rapid *** reactor performance was evaluated to minimize the sulfur content in the naphtha *** to the protective coating,the sulfur conversion stabilized at 90%.The results of this work establish the use of natural clay-based catalysts in a continuous,three-phase ODS,particularly with regard to proving long-term *** also showed that modest ODS can be achieved using an environmentally friendly oxidant,at mild operating conditions,whilst maintaining stability.

关键词： Natural kaoline Desulfurization Three-phase Oscillatory baffled reactor

A Comprehensive Review on Charging Topologies and Power electronic Converter Solutions for electric Vehicles

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Journal of Modern Power Systems and Clean energy 2024年第3期12卷 675-694页

作者： Abdelfatah Ali Hossam H.H.Mousa Mostafa F.Shaaban Maher A.Azzouz Ahmed S.A.awad the Department of electrical engineering American University of Sharjah26666 SharjahUnited Arab Emirates the Department of electrical engineering South Valley University83523 QenaEgypt the Department of electrical and Computer engineering University of WindsorWindsorON N9B 3P4 Canada electrical engineering Department Qatar UniversityDoha 2713Qatar Department of electrical and Computer engineering Sultan Qaboos UniversityMuscat123Oman

electric vehicles(eVs)are becoming more popular worldwide due to environmental concerns,fuel security,and price *** performance of eVs relies on the energy stored in their batteries,which can be charged using either AC(slow)or DC(fast)***,eVs can also be used as mobile power storage devices using vehicle-to-grid(V2G)*** electronic converters(PeCs)have a constructive role in eV applications,both in charging eVs and in ***,this paper comprehensively investigates the state of the art of eV charging topologies and PeC solutions for eV *** examines PeCs from the point of view of their classifications,configurations,control approaches,and future research prospects and their impacts on power *** can be classified into various topologies:DC-DC converters,AC-DC converters,DC-AC converters,and AC-AC *** address the limitations of traditional DC-DC converters such as switching losses,size,and high-electromagnetic interference(eMI),resonant converters and multiport converters are being used in high-voltage eV ***,power-train converters have been modified for high-efficiency and reliability in eV *** paper offers an overview of charging topologies,PeCs,challenges with solutions,and future trends in the field of the eV charging station applications.

关键词： Charging station charging topology electric vehicle power electronic converter vehicle-to-grid

A stepwise optimization strategy to formulate in situ gelling formulations comprising fluconazole-hydroxypropyl-beta-cyclodextrin complex loaded niosomal vesicles and eudragit nanoparticles for enhanced antifungal activity and prolonged ocular delivery

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Asian Journal of Pharmaceutical Sciences 2020年第5期15卷 617-636页

作者： Heba elmotasem Ghada e.A.awad Pharmaceutical Technology Department National Research CentreCairo 12622Egypt Chemistry of Natural and Microbial Product Department National Research CentreCairo 12622Egypt

Fungal keratitis and endopthalmitis are serious eye ***(FL)is indicated for their treatment,but suffers from poor topical ocular *** study was intended to improve and prolong its ocular *** niosomal vesicles were prepared using span ***,polymeric nanoparticles were prepared using cationic eudragit RS100 and eudragit *** investigated particles had adequate entrapment efficiency(ee%),nanoscale particle size and high zeta ***,formulations were optimized using full factorial ***-HP-β-CD complex was encapsulated in selected eudragit nanoprticles(FL-CD-eRS1)and niosmal *** niosomes were further coated with cationic and bioadhesive chitosan(FL-CD-Nios-ch).ee%for FL-CD-eRS1 and FL-CD-Niosch formulations were 76.4%and 61.7%;particle sizes were 151.1 and 392 nm;also,they exhibited satisfactory zeta potential+40.1 and+28.5 m *** situ gels were prepared by poloxamer P407,HPMC and chitosan and evaluated for gelling capacity,rheological behavior and gelling *** increase the precorneal residence time,free drug and selected nano-formulations were incorporated in the selected in situ *** study revealed sustained release within 24 *** through excised rabbits corneas demonstrated enhanced drug flux and large AUC0-6 h in comparison to plain *** permeation of selected formulations labeled with Rhodamine B was visualized by Confocal laser *** study and in vivo tolerance test evidenced *** vivo susceptibility test using Candida albicans depicted enhanced growth inhibition and sustained *** this study the adopted stepwise optimization strategy combined cylodextrin complexation,drug nano-encapsulation and loading within thermosenstive in situ ***,the developed innovated formulations displayed boosted corneal permeation,enhanced antifungal activity and prolonged action.

关键词： Fluconazole Ocular eudragit nanoparticles Cyclodextrin Niosomes In situ gel

Bulk etch rates of CR-39 at high etchant concentrations:diffusionlimited etching

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Nuclear Science and Techniques 2020年第12期31卷 41-49页

作者： e.M.awad M.A.Rana Mushtaq Abed Al-Jubbori Physics Department Faculty of ScienceMenoufia UniversityShebin El-KoomMenoufia 32511Egypt MeRADD Instrumentation Control and Computer Complex(ICCC)PARAS Building18-KM Multan RoadP.O.ChungLahorePakistan Department of Physics College of Education for Pure SciencesUniversity of MosulMosul 41001Iraq

Systematic CR-39 bulk etching experiments were conducted over a wide range of concentrations(2–30 N)of NaOH-based *** analysis and a deep discussion of the results are presented.A comprehensive nuclear track chemical etching data bank was *** regimes of CR-39 bulk etching were *** I spans etchant concentrations from 2 to 12 *** II spans concentrations from 12 to 25 *** call this the dynamic bulk etching *** III is for concentrations greater than 25 *** this regime,the bulk etch rate is saturated with respect to the etchant *** classification is discussed and *** role of ethanol in NaOH-based etchants is explored and discussed.A parameter called the “reduced bulk etch rate” is defined here,which helps in analyzing the dependence of bulk etching on the amount of ethanol in the *** bulk etch rate shows a natural logarithmic dependence on the density of ethanol in the etchant.

关键词： CR-39 detector ethanol Bulk etch rate Reduced bulk etch rate Diffusion-limited etching Concentration-limited etching

An Improved DeepNN with Feature Ranking for Covid-19 Detection

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Computers, Materials & Continua 2022年第5期71卷 2249-2269页

作者： Noha e.el-Attar Sahar F.Sabbeh Heba Fasihuddin Wael A.awad Faculty of Computers and Artificial Intelligence Benha UniversityBenha13518Egypt University of Jeddah College of Computer Science and EngineeringJeddah21493Kingdom of Saudi Arabia Faculty of Computers and Information Damietta UniversityDamietta34711Egypt

The outbreak of Covid-19 has taken the lives of many patients so *** symptoms of COVID-19 include muscle pains,loss of taste and smell,coughs,fever,and sore throat,which can lead to severe cases of breathing difficulties,organ failure,and ***,the early detection of the virus is very ***-19 can be detected using clinical tests,making us need to know the most important symptoms/features that can enhance the decision *** this work,we propose a modified multilayer perceptron(MLP)with feature selection(MLPFS)to predict the positive COVID-19 cases based on symptoms and features from patients’electronic medical records(eMR).MLPFS model includes a layer that identifies the most informative symptoms to minimize the number of symptoms base on their relative *** the model with only the highest informative symptoms can fasten the learning process and increase *** were conducted using three different COVID-19 datasets and eight different models,including the proposed *** show that MLPFS achieves the best feature reduction across all datasets compared to all other experimented ***,it outperforms the other models in classification results as well as time.

关键词： Covid-19 feature selection deep learning

Synthesis of Antipyrine Derivatives Derived from Dimedone

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Chinese Journal of Chemistry 2007年第4期25卷 570-573页

作者： eIASHRY e. S. H. awad L. F. IBRAHIM e. I. BDeeWY O. Kh. Chemistry Department Faculty of Science Alexandria University Alexandria Egypt Suez Cannel University lsmailia Egypt

Coupling of dimedone with the diazonium salt of 4-aminoantipyrine afforded 2,3-dimethyl-4-[2-（5,5-dimethyl- 2,6-dioxocyclohex-2-ylidend）-hydrazino]-5-oxo-1-phenylpyrazoline （3）. Reaction of 3 with excess phenylhydrazine gave the mixed trishydrazone derivative 4. Treatment of 3 with hydroxylamine produced the bisoxime 5 which upon dehydrative cyclization with acetic anhydride gave the corrsponding tetrahydrobenzo[d][1,2,3]triazole derivative 7. A one-pot synthesis of 7 was done by reacting 3 with hydroxylamine hydrochloride in pyridine, followed by heatment with acetic anhydride.

关键词： dimedone antipyrine 1,2,3-triazole phenylhydrazone

Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice

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Bone Research 2017年第2期5卷 95-108页

作者： eric e Beier Tzong-Jen Sheu emily A Resseguie Masahiko Takahata Hani A awad Deborah A Cory-Slechta J edward Puzas Department of environmental Medicine University of Rochester School of Medicine and Dentistry Rochester NY USA Department of environmental and Occupational Medicine Rutgers University Piscataway NJ USA and Center for Musculoskeletal Research University of Rochester School of Medicine and Dentistry Rochester NY USA

Stress during prenatal development is correlated with detrimental cognitive and behavioral outcomes in offspring. However, the long-term impact of prenatal stress(PS) and disrupted glucocorticoid signaling on bone mass and strength is not understood. In contrast, the detrimental effect of lead(Pb) on skeletal health is well documented. As stress and Pb act on common biological targets via glucocorticoid signaling pathways and co-occur in the environment, this study first sought to assess the combined effect of stress and Pb on bone quality in association with alterations in glucocorticoid signaling. Bone parameters were evaluated using microCT, histomorphometry, and strength determination in 8-month-old male mouse offspring subjected to PS on gestational days 16 and 17, lifetime Pb exposure(100 p.p.m. Pb in drinking water), or to both. Pb reduced trabecular bone mass and, when combined with PS, Pb unmasked an exaggerated decrement in bone mass and tensile strength. Next, to characterize a mechanism of glucocorticoid effect on bone, prednisolone was implanted subcutaneously(controlled-release pellet, 5 mg·kg^(-1) per day) in 5-month-old mice that decreased osteoblastic activity and increased sclerostin and leptin levels. Furthermore, the synthetic glucocorticoid dexamethasone alters the anabolic Wnt signaling pathway. The Wnt pathway inhibitor sclerostin has several glucocorticoid response elements, and dexamethasone administration to osteoblastic cells induces sclerostin expression. Dexamethasone treatment of isolated bone marrow cells decreased bone nodule formation, whereas removal of sclerostin protected against this decrement in ***, these findings suggest that bone loss associated with steroid-induced osteoporosis is a consequence of sclerostin-mediated restriction of Wnt signaling, which may mechanistically facilitate glucocorticoid toxicity in bone.

关键词： Sclerostin prenatal negative

Is analysis of lower esophageal sphincter vector volumes of value in diagnosing gastroesophageal reflux disease?

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World Journal of Gastroenterology 2003年第1期9卷 174-178页

作者： Robert e.Marsh Christopher L.Perdue Ziad T.awad Patrice Watson mohamed Selima Richard e.Davis Charles J.Filipi Department of Surgery Creighton University School of MedicineOmaha Nebraska USA Department of Preventive Medicine Creighton University School of MedicineOmaha Nebraska USA

AIM:With successful surgical treatment of gastroesophageal reflux disease(GeRD),there is interest in understanding the anti-reflux barrier and its mechanisms of *** date, the potential use of vector volumes to predict the DeMeester score has not been adequately explored. MeTHODS:627 patients in the referral database received esophageal manometry and ambulatory 24-hour pH *** data included LeS resting pressure(LeSP), overall LeS length(OL)and abdominal length(AL),total vector volume(TVV)and intrabdominal vector volume(IVV). ReSULTS:In cases where LeSP,TVV or IVV were all below normal,there was an 81.4%probability of a positive DeMeester *** cases where all three were normal, there was an 86.9%probability that the DeMeester score would be ***-operating characteristics(ROC) for LeSP,TVV and IVV were nearly identical and indicated no useful cut-off *** regression demonstrated that LeSP and IVV had the strongest association with a positive DeMeester score;however,the regression formula was only 76.1%accurate. CONCLUSION:While the indices based on TVV,IVV and LeSP are more sensitive and specific,respectively,than any single measurement,the measurement of vector volumes does not add significantly to the diagnosis of GeRD.

关键词： Adolescent Adult Aged Aged, 80 and over Child Child, Preschool esophagogastric Junction Female Gastroesophageal Reflux Humans Hydrogen-Ion Concentration Male Manometry Middle Aged ROC Curve Regression Analysis

exome sequencing identifies a likely causative variant in 53%of families with ciliopathy-related features on renal ultrasound after excluding NPHP1 deletions

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Genes & Diseases 2024年第5期11卷 40-43页

作者： Konstantin Deutsch Verena Klambt Thomas M.Kitzler Tilman Jobst-Schwan Ronen Schneider Florian Buerger Steve Seltzsam Sherif el Desoky Jameela A.Kari Farkhanda Hafeez Maria Szczepanska Loai A.eid Hazem S.awad Muna Al-Saffar Neveen A.Soliman Velibor Tasic Camille Nicolas-Frank Kirollos Yousef Luca M.Schierbaum Sophia Schneider Abdul Halawi Izzeldin elmubarak Katharina Lemberg Shirlee Shril Shrikant M.Mane Nancy Rodig Friedhelm Hildebrandt Division of Nephrology Department of PediatricsBoston Children’s HospitalHarvard Medical SchoolBostonMA 02215USA Department of Pediatric Gastroenterology Nephrology and Metabolic DiseasesCharite Universitatsmedizin BerlinBerlin 13353Germany Berlin Institute of Health at Charitee Universitatsmedizin Berlin BIH Biomedical Innovation AcademyBIH Charite Clinician Scientist ProgramBerlin 10178Germany Department of Nephrology and Hypertension FriedrichAlexander-Universitat Erlangen-NurnbergErlangen 91054Germany Department of Pediatrics Faculty of Medicine King Abdulaziz UniversityPediatric Nephrology Center of ExcellenceKing Abdulaziz University HospitalJeddah 21589Saudi Arabia Department of Pediatric Nephrology The Children’s Hospital and Institute of Child HealthLahore 54000Pakistan Department of Pediatrics Faculty of Medical Sciences in ZabrzeMedical University of Silesia in KatowiceKatowice 40-752Poland Dubai Hospital and Al-Jalila Children’s Specialty Hospital Kidney Center of ExcellenceDubai 4545United Arab Emirates Department of Genetics and Genomics UAE UniversityAbu Dhabi 15551United Arab Emirates Department of Pediatrics Division of Genetics and GenomicsBoston Children’s HospitalHarvard Medical SchoolBostonMA 02215USA Department of Pediatrics Center of Pediatric Nephrology and TransplantationKasr Al Ainy School of MedicineCairo UniversityCairo 11562Egypt egypt Center for Research and Regenerative Medicine(eCRRM) Cairo 11511Egypt Medical Faculty Skopje University Children’s HospitalSkopje 1000North Macedonia Department of Genetics Yale University School of MedicineNew HavenCT 06520USA

Nephronophthisis-related ciliopathies(NPHP-RC)represent one of the most common causes of chronic kidney disease in the first three decades of life and are characterized by a broad genetic and clinical heterogeneity.1 To date,more than 90 genes have been identified that cause autosomalrecessive NPHP-RC if mutated,accounting for up to 60%of cases.1 Among these,homozygous deletions of NPHP1 are the most common *** genes localize to primary cilia,basal bodies,or the centrosome and lead to a primary ciliary disruption if mutated,thereby causing a broad phenotypical spectrum.1 Patients that suffer from NPHP-RC can either have an isolated renal phenotype,such as polyuria,polydipsia,decreased urinary concentration ability,and secondary enuresis due to loss of tubular function,or present with extrarenal symptoms including retinal degeneration,cerebellar vermis hypoplasia,or hepatic *** are often diagnosed in early adolescence,reaching end-stage renal disease before 25 years of age,but early onset and rapidly progressive forms of NPHP-RC also exist.1 Renal ultrasound indicates kidneys of normal or reduced renal length with increased echogenicity and corticomedullary cysts.

关键词： degeneration urinary likely

Postmyotomy dysphagia after laparoscopic surgery for achalasia

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World Journal of Gastroenterology 2003年第5期9卷 1129-1131页

作者： Yutaka Shiino Ziad T.awad Gleb R. Haynatzki Richard e. Davis Ronald A. Hinder Charles J. Filipi Department of Surgery Creighton University601 N.30~(th)StreetOmahaNE 68131USA Department of Medicine Creighton University601 N.30~(th) StreetOmahaNE 68131USA Department of Surgery Mayo Clinic Jacksonville4500 San Pablo RoadJacksonvilleFL 32224USA

AIM: To determine predictive factors for postoperative dysphagia after laparoscopic myotomy for ***: Logistic regression was used to investigate the possible association between the response (postoperative dysphagia, with two levels: none/mild and moderate/severe)and several plausible predictive ***: eight patients experienced severe or moderate postoperative dysphagia. The logistic regression revealed that only the severity of preoperative dysphagia (with four levels; mild, moderate, severe, and liquid) was a marginally significant (P=0.0575) predictive factor for postoperative ***: The severity of postoperative dysphagia is strongly associated with preoperative dysphagia. Preoperative symptomatology can significantly impact patient outcome.

关键词： Deglutition Disorders Digestive System Surgical Procedures esophageal Achalasia Female Humans Laparoscopy Logistic Models Male Postoperative Complications Retrospective Studies Risk Factors Treatment Outcome