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Plasticity of Xyloglucan Composition in Bean （Phaseolus vulgaris）-Cultured Cells during Habituation and Dehabituation to lethal Concentrations of Dichlobenil

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Molecular Plant 2010年第3期3卷 603-609页

作者： A. Alonso-Simon l. Neumetzler R Garcia-Angulo A.e. encina J.l. Acebes J.M. Alvarez T. Hayashi Area de Fisiologia Vegetal Universidad de Leon E-24071 Leon Spain Max Planck Institute of Molecular Plant Physiology 14476 Golm Germany Kyoto University RISH Gokasho Uji Kyoto 611-0011 Japan

Bean cells that have been habituated to grow in a lethal concentration （12 μM） of 2,6-dichlorobenzonitrile （dichlobenil or DCB, a cellulose biosynthesis inhibitor） are known to have decreased cellulose content in their cell walls. Xyloglucan, which is bound to cellulose and together with it forms the main loading network of plant cell walls, has also been described to decrease in habituated cells, but whether the change on cellulose affects the xyloglucan structure besides its abundance has not been analyzed. Fragmentation analysis with xyloglucan-specific endoglucanase （XeG） and endocellulase revealed that habituation to DCB caused a change in the fine structure of xyloglucan, namely a decrease in fucosyl residues attached to the galactosyl-xylosyl residues along the glucan backbone. After the removal of herbicide from the medium （dehabituated cells）, xyloglucan recovered its fucosyl residues. In addition, some cello-oligosaccharides could be detected only in habituated cells＇ xyloglucan digested by XeG and endocellulase, corresponding to a glucan co- valently bound or co-precipitated with the hemicelluloses. These results show that structural flexibility of cell walls relies in part on the plasticity of xyloglucan composition and opens up new perspectives to further research in this field.

关键词： Bean 2,6-dichlorobenzonitrile habituation and dehabituation OlIMP (Oligosaccharides Mass Profiling) xyloglucan.

维生素D与儿童青少年心理健康相关性的研究进展

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中国学校卫生 2024年第7期45卷 1055-1058,1064页

作者：王吕珧徐保玉汤婷王君苏普玉汪耿夫安徽医科大学公共卫生学院妇幼保健医学系合肥230032 安徽医科大学预防医学专业安徽医科大公共卫生学院儿少卫生与妇幼保健学系/出生人口健康教育部重点实验室/人口健康与优生安徽省重点实验室

维生素D(Vit D)作为一种重要的营养素,在儿童青少年生长发育过程中的重要作用已被广泛认可,但其与心理健康之间的关联仍处于探索阶段。通过回顾与总结国内外Vit D对儿童青少年常见心理健康问题影响的相关研究,包括抑郁症状、焦虑症状、... 详细信息

维生素D(Vit D)作为一种重要的营养素,在儿童青少年生长发育过程中的重要作用已被广泛认可,但其与心理健康之间的关联仍处于探索阶段。通过回顾与总结国内外Vit D对儿童青少年常见心理健康问题影响的相关研究,包括抑郁症状、焦虑症状、自杀相关心理行为,以及Vit D影响心理健康的生物学机制等,旨在为改善中国儿童青少年心理健康和开展未来研究提供科学依据与思路。

关键词：维生素D 精神卫生儿童青少年

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Successful treatment with hysteroscopy for infertility due to isthmocele and hydrometra secondary to cesarean section: A case report

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World Journal of Clinical Cases 2019年第6期7卷 753-758页

作者： luis Pablo lópez Rivero Miguel Jaimes Felipe Camargo esther lópez-Bayghen Instituto de Infertilidad y Genética México SC Departamento de Toxicología Centro de Investigación de Estudios

BACKGROUND An isthmocele is a scar defect in the uterine wall due to a cesarean section. Its prevalence is unknown,but it has been associated with secondary ***,we present a case where the patient suffered from an isthmocele that was associated with persistent hydrometra,which developed during in vitro *** SUMMARY The patient underwent hysteroscopic surgery,which successfully resolved the isthmocele as well as the hydrometra. Afterward,two high-quality,euploid embryos,determined by morphological assessment and pre-implantation genetic diagnostic testing,were transferred. This resulted in uterine pregnancy,as determined byserum β-human chorionic gonadotropin levels on day 14(180 m U/ml) and ultrasound-confirmed presence of a gestational sac with a positive embryocardia at week 6. The pregnancy reached 36 wk without any complications,and the product was born in good health. We report a successful isthmocele treatment in a patient with secondary infertility,in which the isthmocele was the cause of persistent *** Hydrometra caused by secondary cesarean is an infertility factor,which can be corrected by hysteroscopy plus ablation of the isthmocele.

关键词： In vitro fertilization Isthmocele Hydrometra Case report

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表面纹理对水泥吸波路面微波除冰性能的影响

科学技术与工程 2024年第14期24卷 6003-6011页

作者：刘浩翔王选仓赵静陈律任俊儒长安大学公路学院西安710064 陆军勤务学院重庆401331

为了增强水泥混凝土路面除冰效率,制备了吸波及疏水涂层,并在此基础上,构建了8种不同表面纹理,用于探究表面纹理、吸波材料对微波升温性能的影响。首先,以石墨为微波吸收剂,掺加纳米SiO_(2)制备了兼具疏水和吸波性能的水泥基涂层;通过... 详细信息

为了增强水泥混凝土路面除冰效率,制备了吸波及疏水涂层,并在此基础上,构建了8种不同表面纹理,用于探究表面纹理、吸波材料对微波升温性能的影响。首先,以石墨为微波吸收剂,掺加纳米SiO_(2)制备了兼具疏水和吸波性能的水泥基涂层;通过机器学习改进铺砂法获得不同纹理的平均构造深度(mean texture depth,MTD);为了评估MTD对微波升温效率、均匀性的影响,采用课题组自行研发的微波除冰车进行微波升温试验;同时,测试了普通及涂层混凝土表面的接触角,进行了冰-混凝土冰黏附性剪切试验,用于评价本文所制备涂层的除冰效果。最后,为了保证本文设计涂层的抗滑性能,还进行了表面抗滑摆值测试。结果表明:不同程度纹理和吸波涂层两者耦合作用增强水泥路面的吸波升温效率,但纹理对升温均匀性有负面影响;当MTD从0.41 mm(未处理表面)提高至2.11mm时,吸波涂层试件的吸波升温效率提高1.42倍。同时,涂层也显著增强了试件表面的接触角,接触角从25.5°提升至104°,进而冰黏附强度降低。当设计厚度为1.5 mm时,在满足抗滑性的同时涂层仍具有较好的吸波性能。

关键词：微波除冰水泥路面纹理吸波涂层纳米材料

Groundwater recharge site suitability analysis through multiinfluencing factors(MIF)in West Bengal dry-land areas,West Bengal,India

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Acta Geochimica 2022年第6期41卷 1030-1048页

作者： Kartic Bera Michelle e.Newcomer Pabitra Banik Agricultural and ecological Research Unit Indian Statistical Institute203Barrackpore Trunk RoadKolkataWest Bengal700108India lawrence Berkeley National laboratory Earth&Environmental Sciences AreaBerkeleyCAUSA

Groundwater levels are gradually declining in basins around the world due to anthropogenic and natural *** is not the only factor contributing to change in groundwater levels,population growth and economic progress are leading to increased water *** used for agricultural irrigation are expanding,necessitating the use of artificial groundwater recharge as a method to sustain pumping and enhance *** present study delineates potential locations of significant groundwater resources that already exist using a geostatistical approach as a method to identify potential groundwater recharge *** Multi-Influencing Factors(MIF)technique was applied to determine the relationship between different landscape and climatic factors that influence groundwater *** include topography,climate,hydrogeology,population,economic change,and *** of these factors enabled the identification of potential locations of groundwater suitable for artificial recharge efforts based on weights derived through the MIF *** applied these weights to derive a groundwater recharge index(GRI)*** map was delineated into three groundwater recharge zones classified by their potential areal coverage as a metric for recharge suitability,namely low,medium and high suitability,occupying areas of 8625 km2(30.06%),9082 km2(31.65%),and 10,989 km~2(38.29%),*** findings have important implications for designing sustainable groundwater development and land-use plans for the coming century.

关键词： Dry-lands Multi-influencing factor(MIF) Weighted index overlay(WIO) Groundwater suitable for artificial recharge(GSAR) Recharge volume(RV)

Vitamin D in prostate cancer

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Asian Journal of Andrology 2018年第3期20卷 244-252页

作者： Donald l Trump Jeanny B Aragon-Ching Inova Schar Cancer Institute Inova Health System Fairfax VA 22037 USA.

Signaling through the vitamin D receptor has been shown to be biologically active and important in a number of preclinical studies in prostate and other cancers. epidemiologic data also indicate that vitamin D signaling may be important in the cause and prognosis of prostate and other cancers. These data indicate that perturbation of vitamin D signaling may be a target for the prevention and treatment of prostate cancer. large studies of vitamin D supplementation will be required to determine whether these observations can be translated into prevention strategies. This paper reviews the available data in the use of vitamin D compounds in the treatment of prostate cancer. Clinical data are limited which support the use of vitamin D compounds in the management of men with prostate cancer. However, clinical trials guided by existing preclinical data are limited.

关键词： androgens CYP24A1 inflammation prostate cancer vitamin D analogs

effects of A Top SiO2 Surface layer on Cavity Formation and Helium Desorption in Silicon

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Journal of Rare earths 2006年第z1期24卷 78-82页

作者： liu Changlong Yin lijun lü Yiying Alquier D Department of Physics School of Science Tianjin University Tianjin 300072 China Tianjin Key laboratory of low Dimension Materials Physics and Preparing Technology Institute of Advanced Materials Physics Faculty of Science Tianjin 300072 China Department of Physics School of Science Tianjin University Tianjin 300072 China Department of Physics School of Science Tianjin University Tianjin 300072 China LMP/STMicroelectronics 16 rue Pierre et Marie Curie B. P. 7155 F37071 Tours Cedex France

Cz n-type Si (100) samples with and without a top SiO2 layer were implanted with 40 keV helium ions at the same dose of 5×1016 cm-2. Cross-sectional transmission electron microscopy (XTeM) and thermal desorption spectroscopy (THDS) were used to study the thermal evolution of cavities upon and helium thermal release, respectively. XTeM results show that the presence of the top SiO2 layer could suppress the thermal growth of cavities mainly formed in the region close to the SiO2/Si interface, which leads to the reduction in both the cavity band and cavity density. THDS results reveal that the top oxide layer could act as an effective barrier for the migration of helium atoms to the surface, and it thus gives rise to the formation of more overpresurrized bubbles and to the occurrence of a third release peak located at about 1100 K. The results were qualitively discussed by considering the role of the oxide surface layer in defect migration and evolution upon annealing.

关键词： silicon SiO2 layer helium implantation cavities helium release

Developmental stages and quality traits of giant African land snails [<i>Archachatina marginata</i>(swainson)] eggs

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Natural Science 2013年第10期5卷 1121-1126页

作者： B. Okon l. A. Ibom I. e. ebenso A. e. Bassey Department of Animal Science University of Calabar Calabar Nigeria Departrment of Animal Science University of Uyo Uyo Nigeria

Sixty sexually mature purebred black-skinned Archachatina marginata snails with weight ranging from 120.50 g to 135.70 g were used to generate eggs in this study. The eggs collected were incubated in a chamber filled with loamy soil for appropriate observation and assessment (cracking at four days intervals to check snailet’s development). Results obtained from the study showed that at laying snail egg weights ranged from 1.54 - 2.45 g (mean of 2.00 g). The egg lengths and widths ranged from 13.50 - 16.90 mm (mean of 15.20 mm) and 10.00 - 12.70 mm (mean of 11.40 mm) respectively. The results also revealed that at laying (day one) the egg content was translucent or clear (blank) when observed with light from a powered microscope. Observation of eggs on day four showed the formation of embryo with a semi-transparent cup attached to a long string body. On day 12, some specific organs of the snailet had developed, and there was a reduction in the liquid content. On day 28, the snailet was fully formed, but the shell still contained very small volume of liquid. The snailet hatched on day 29.

关键词： Development Quality Traits eggs Snail Stages

Updates in endocrine therapy for metastatic breast cancer

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Cancer Biology & Medicine 2022年第2期19卷 202-212页

作者： Poorni M.Manohar Nancy e.Davidson University of Washington/Seattle Cancer Care Alliance Seattle 98109WAUSA Fred Hutchinson Cancer Research Center Seattle 98109WAUSA

endocrine therapy(eT)remains the mainstay of treatment for steroid hormone receptor-positive,human epidermal growth factor 2(HeR2)-negative metastatic breast cancer(MBC).Tumor resistance to hormone therapy has led to the development of novel endocrine drug combinations,transforming the landscape of MBC *** options for eT are expanding,with promising agents in the *** MBC remains incurable,many patients can enjoy years of survival with good quality of life by cycling through the many available *** the plethora of available agents and rapid approvals,clinicians look to evidencebased guidelines to assist in treatment selection to maximize patient *** this review,we provide a contemporary review of the advances in eT and a suggested algorithm to guide clinicians in daily management of patients with hormone receptor-positive,HeR2-negative *** will discuss landmark trials and highlight their impact in reshaping treatment ***,we will provide a glimpse into advances on the horizon and the promise they bring to improve outcomes in patients with advanced breast cancer.

关键词： endocrine therapy metastatic breast cancer