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Impact of COVID-19 on liver transplant recipients: A nationwide cohort study evaluating hospitalization, transplant rejection, and inpatient mortality

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World Journal of Transplantation 2024年第2期14卷 62-75页

作者： Faisal Inayat Pratik Patel Hassam Ali Arslan Afzal Hamza Tahir Ahtshamullah Chaudhry Rizwan Ishtiaq attiq ur rehman Kishan Darji Muhammad Sohaib Afzal Gul Nawaz Alexa Giammarino Sanjaya K Satapathy Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Division of Gastroenterology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States Division of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Jefferson Einstein HospitalPhiladelphiaPA 19141United States Department of Internal Medicine St.Dominic's HospitalJacksonMS 39216United States Department of Internal Medicine Saint Francis Hospital and Medical CenterHartfordCT 06105United States Division of Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine Campbell University and Cape Fear Valley Medical CenterFayettevilleNC 28301United States Department of Internal Medicine North Shore University Hospital and Zucker School of Medicine at Hofstra UniversityManhassetNY 11030United States Division of Hepatology North Shore University Hospital and Zucker School of Medicine at Hofstra UniversityManhassetNY 11030United States

BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has posed a major public health concern *** with comorbid conditions are at risk of adverse outcomes following *** organ transplant recipients with concurrent immunosuppression and comorbidities are more susceptible to a severe COVID-19 *** could lead to higher rates of inpatient complications and mortality in this patient ***,studies on COVID-19 outcomes in liver transplant(LT)recipients have yielded inconsistent *** To evaluate the impact of the COVID-19 pandemic on hospital-related outcomes among LT recipients in the United *** We conducted a retrospective cohort study using the 2019–2020 National Inpatient Sample *** with primary LT hospitalizations and a secondary COVID-19 diagnosis were identified using the International Classi-fication of Diseases,Tenth Revision coding *** primary outcomes included trends in LT hospitalizations before and during the COVID-19 *** outcomes included comparative trends in inpatient mortality and transplant rejection in LT *** A total of 15720 hospitalized LT recipients were *** 0.8% of patients had a secondary diagnosis of COVID-19 *** both cohorts,the median admission age was 57 *** linear trends for LT hospitalizations did not differ significantly before and during the pandemic(P=0.84).The frequency of in-hospital mortality for LT recipients increased from 1.7% to 4.4% between January 2019 and December *** to the pre-pandemic period,a higher association was noted between LT recipients and in-hospital mortality during the pandemic,with an odds ratio(OR)of 1.69[95% confidence interval(CI):1.55-1.84),Puring the COVID-19 pandemic had a higher associ

关键词： Liver transplant recipients Solid organ transplantation COVID-19 Hospitalization Transplant rejection Mortality

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Association between acute peripancreatic fluid collections and early readmission in acute pancreatitis:A propensity-matched analysis

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World Journal of Experimental Medicine 2024年第2期14卷 75-88页

作者： Hassam Ali Faisal Inayat Waqas Rasheed Arslan Afzal Ahtshamullah Chaudhry Pratik Patel attiq ur rehman Muhammad Sajeel Anwar Gul Nawaz Muhammad Sohaib Afzal Amir H Sohail Subanandhini Subramanium Dushyant Singh Dahiya Deepa Budh Babu P Mohan Douglas G Adler Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTX 79430United States Department of Internal Medicine St.Dominic’s HospitalJacksonMS 39216United States Department of Gastroenterology Mather Hospital and Hofstra University Zucker School of MedicinePort JeffersonNY 11777United States Department of Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Department of Internal Medicine Louisiana State University HealthShreveportLA 71103United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 64108United States Department of Internal Medicine St.Barnabas Hospital and Albert Einstein College of MedicineBronxNY 10457United States Department of Gastroenterology and Hepatology University of Utah School of MedicineSalt Lake CityUT 84132United States Center for Advanced Therapeutic Endoscopy Porter Adventist HospitalCentura HealthDenverCO 80210United States

BACKGROUND Patients with acute pancreatitis(AP)frequently experience hospital readmissions,posing a significant burden to healthcare *** peripancreatic fluid collection(APFC)may negatively impact the clinical course of *** could worsen symptoms and potentially lead to additional ***,clinical evidence regarding the specific association between APFC and early readmission in AP remains *** the link between APFC and readmission may help improve clinical care for AP patients and reduce healthcare *** To evaluate the association between APFC and 30-day readmission in patients with *** This retrospective cohort study is based on the Nationwide Readmission Database for *** with a primary diagnosis of AP were *** were categorized into those with and without APFC.A 1:1 propensity score matching for age,gender,and Elixhauser comorbidities was *** primary outcome was early readmission *** outcomes included the incidence of inpatient complications and healthcare *** analyses used Mann-Whitney U andχ2 tests,while Cox regression models assessed 30-day readmission risks and reported them as adjusted hazard ratios(aHR).Kaplan-Meier curves and log-rank tests verified readmission *** A total of 673059 patients with the principal diagnosis of AP were *** these,5.1%had APFC on initial *** propensity score matching,each cohort consisted of 33914 *** with APFC showed a higher incidence of inpatient complications,including septic shock(3.1%vs 1.3%,P<0.001),portal venous thrombosis(4.4%vs 0.8%,P<0.001),and mechanical ventilation(1.8%vs 0.9%,P<0.001).The length of stay(LOS)was longer for APFC patients[4(3-7)vs 3(2-5)days,P<0.001],as were hospital charges($29451 vs$24418,P<0.001).For 30-day readmissions,APFC patients had a higher rate(15.7%vs 6.5%,P<0.001)and a longer median readmission LOS(4 vs 3 days,P<0.001).The APF

关键词： Acute pancreatitis Acute peripancreatic fluid collections Readmission predictors Inpatient complications Healthcare utilization and costs

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Early versus delayed necrosectomy in pancreatic necrosis:A population-based cohort study on readmission,healthcare utilization,and in-hospital mortality

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World Journal of Methodology 2024年第3期14卷 55-67页

作者： Hassam Ali Faisal Inayat Vinay Jahagirdar Fouad Jaber Arslan Afzal Pratik Patel Hamza Tahir Muhammad Sajeel Anwar attiq ur rehman Muhammad Sarfraz Ahtshamullah Chaudhry Gul Nawaz Dushyant Singh Dahiya Amir H Sohail Muhammad Aziz Division of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine University of Missouri-Kansas CityKansas CityMO 64108United States Division of Gastroenterology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States Department of Internal Medicine Jefferson Einstein HospitalPhiladelphiaPA 19141United States Department of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Division of Gastroenterology and Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine St.Dominic's HospitalJacksonMS 39216United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology and Hepatology The University of ToledoToledoOH 43606United States

BACKGROUND Acute necrotizing pancreatitis is a severe and life-threatening *** poses a considerable challenge for clinicians due to its complex nature and the high risk of *** minimally invasive and open necrosectomy procedures have been *** advancements in treatment modalities,the optimal timing to perform necrosectomy lacks *** To evaluate the impact of necrosectomy timing on patients with pancreatic necrosis in the United *** A national retrospective cohort study was conducted using the 2016-2019 Nationwide Readmissions *** with non-elective admissions for pancreatic necrosis were *** participants were divided into two groups based on the necrosectomy timing:The early group received intervention within 48 hours,whereas the delayed group underwent the procedure after 48 *** various intervention techniques included endoscopic,percutaneous,or surgical *** major outcomes of interest were 30-day readmission rates,healthcare utilization,and inpatient *** A total of 1309 patients with pancreatic necrosis were *** propensity score matching,349 cases treated with early necrosectomy were matched to 375 controls who received delayed *** early cohort had a 30-day readmission rate of 8.6% compared to 4.8%in the delayed cohort(P=0.040).Early necrosectomy had lower rates of mechanical ventilation(2.9%vs 10.9%,Purred lower healthcare costs,with median total charges of $52202 compared to$147418 in the delayed *** in the early cohort also had a relatively shorter median length of stay(6 vs 16 days,Pur findings show that

关键词： Acute necrotizing pancreatitis Pancreatic necrosis Early necrosectomy Delayed necrosectomy Readmission,Healthcare costs Mortality

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铁道车辆蛇行频率变化机理及其对车体蛇行稳定性的影响

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Acta Mechanica Sinica 2023年第8期39卷 148-165页

作者：孙建锋焦卫东蒋永华唐超 attiq ur rehman 鄂世举 Key Laboratory of Intelligent Operation and Maintenance Technology and Equipment for urban Rail Transit of Zhejiang Province Zhejiang Normal University Jinhua 321004 China School of Engineering Zhejiang Normal University Jinhua 321004 China Xingzhi College Zhejiang Normal University Lanxi 321004 China

蛇行频率是轮轨系统固有的特征参数并随着运行速度的变化而发生连续变化,能够影响车辆系统的模态行为,从而带来了一系列结构共振相关的动力学问题.本文的研究对象从单轮对系统出发扩展至转向架系统和带两级悬挂的整车系统,重点研究了蛇... 详细信息

蛇行频率是轮轨系统固有的特征参数并随着运行速度的变化而发生连续变化,能够影响车辆系统的模态行为,从而带来了一系列结构共振相关的动力学问题.本文的研究对象从单轮对系统出发扩展至转向架系统和带两级悬挂的整车系统,重点研究了蛇行频率的变化机理及其对车体蛇行稳定性的影响机制.文中提出了一种基于最小模态距离的模态跟踪方法,对蛇行频率和其他模态参数进行连续跟踪,研究了速度激励下轮轨系统及悬挂系数参数对蛇行频率的影响机制.利用极限思想揭示了蛇行频率的饱和机理并给出了频率饱和值的解析表达式.结合模态跟踪方法和正则化的振型及动能幅值分布情况,实现了根轨迹曲线的划分与识别.从模态频率、阻尼比和振型角度,分析并总结了在频率耦合速度(蛇行频率与车体刚性模态频率相等时对应的速度)下的模态行为特征.基于速度与等效锥度的联合变参分析,发现频率耦合速度通过影响最小阻尼比对车体蛇行稳定性产生显著影响.除了模态频率外,车体刚性模态的固有阻尼比也会影响频率耦合速度下的系统最小阻尼比.本文的研究工作揭示了蛇行频率的演变机制,丰富了对蛇行运动现象的理解,为现代轨道车辆的稳定性设计提供了理论依据.

关键词：轮轨系统铁道车辆蛇行运动车辆系统等效锥度轨道车辆模态频率阻尼比

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Poultry Manure as an Organic Fertilizer with or without Biochar Amendment:Influence on Growth and Heavy Metal Accumulation in Lettuce and Spinach and Soil Nutrients

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Phyton-International Journal of Experimental Botany 2021年第2期90卷 651-676页

作者： Hira Javaid Siddiqui Shamim Gul attiq-ur-rehman Kakar Umbreen Shaheen Gul Bano rehman Naqeebullah Khan Samiullah Department of Botany University of BalochistanQuetta87300Pakistan Department of Natural Resource Sciences McGill UniversityQuebecH9X 3V9Canada Department of Chemistry University of BalochistanQuetta87300Pakistan Department of Zoology University of BalochistanQuetta87300Pakistan

This pot-based study investigated the influence of poultry manure and 1:1 mixture of poultry manure+biochar(produced from farmyard manure[FYM]or wood),on the biomass production and concentration of heavy metals in leaves of lettuce and *** concentration of mineral nitrogen(N)and soluble inorganic phosphorus(P)of soils cultivated with these vegetables was also *** application of poultry manure or FYM biochar in soil as 10%(equivalent to 60 t ha^(-1),an estimated 1726.8 kg ha^(-1)N in poultry manure and 1353.9 kg ha^(-1)N in FYM)and 15%amendment(equivalent to 90 t ha^(-1),an estimated 2590.2 kg ha^(-1)N in poultry manure and 2030.8 kg ha^(-1)N in FYM)significantly decreased biomass production of lettuce as compared to control(no fertilizer added)***,mixture of poultry manure with wood-derived biochar at both application rates(i.e.,10%and 15%)and with FYM biochar at lower application rate(i.e.,10%)caused 2-3-fold increase in aboveground plant biomass and 2-14-fold increase in root biomass(purthermore,as compared to control treatment,a significant~2-3-fold increase in aboveground plant biomass was also observed in response to mixture of poultry manure with wood-derived and FYM derived biochars at 10%amendment *** compared to control treatment,concentration of mineral N and soluble inorganic P were higher in soils of all other *** spinach,amendment of poultry manure or its co-amendment with biochar of FYM significantly increased aboveground plant biomass at 7%(equivalent to 42 t ha^(-1))as compared to 3%and 5%amendment rates(equivalent to 18 and 30 t ha^(-1)respectively).The concentration of soil mineral N and soil soluble mineral P was not different between *** lettuce,wood-derived biochar did not reduce concentration of heavy metals(i.e.,manganese(Mn),copper(Cu),iron,(Fe),cadmium(Cd),lead(Pb),nickel(Ni)and cobalt(Co)than FYM-derived biochar while in spinach,as compared to poultry manure,co-amendment of

关键词： Biochar poultry manure lettuce spinach

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Design and Fabrication of a High Voltage Lightning Impulse Generator

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Engineering（科研） 2016年第3期8卷 69-73页

作者： attiq ur-rehman Nasrullah Khan Electrical Engineering Department COMSATS Institute of Information Technology Islamabad Pakistan

This paper reports 10 kV to 100 kV high voltage impulse generator. Generation of variable outputs impulse generator can be designed by combination of flyback transformer and Marx generator which can produce different high voltages. It is a portable device for field. The experimental final results have been taken by using spark gap measurements and voltage divider technique. This high voltage lightning impulse generator produces standard T1/T2 waveshape impulses. The testing of protection devices such as SPD (surge protection device) is extremely important to find out whether these devices can operate in standard conditions or not. That’s why the high voltage lightning impulse generator is developed for such testing. Similarly, our research work consists of modeling and practical design of a 100 kV impulse generator.

关键词： Power Supply Flyback Transformer Marx Generator HV Generator

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Association between alcohol-associated cirrhosis and inpatient complications among COVID-19 patients:A propensity-matched analysis from the United

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World Journal of Virology 2023年第4期12卷 221-232页

作者： Faisal Inayat Hassam Ali Pratik Patel Rubaid Dhillon Arslan Afzal attiq ur rehman Muhammad Sohaib Afzal Laraib Zulfiqar Gul Nawaz Muhammad Hassan Naeem Goraya Subanandhini Subramanium Saurabh Agrawal Sanjaya K Satapathy Department of Internal Medicine Allama Iqbal Medical CollegeLahore 54550PunjabPakistan Department of Internal Medicine East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Gastroenterology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States Department of Gastroenterology Cleveland Clinic FoundationClevelandOH 44195United States Department of Hepatology Mercy Medical CenterBaltimoreMD 21202United States Department of Internal Medicine Louisiana State University HealthShreveportLA 71103United States Department of Internal Medicine Quaid-e-Azam Medical CollegeBahawalpur 63100PunjabPakistan Department of Hepatology Tampa General Medical Group and University of South FloridaTampaFL 33606United States Department of Hepatology North Shore University Hospital and Zucker School of Medicine at Hofstra UniversityManhassetNY 11030United States

BACKGROUND Alcohol-associated cirrhosis(AC)contributes to significant liver-related mortality in the United *** is known to cause immune dysfunction and coagulation *** with comorbid conditions like AC are at risk of worse clinical outcomes from coronavirus disease 2019(COVID-19).The specific association between AC and COVID-19 mortality remains inconclusive,given the lack of robust clinical evi-dence from prior *** To study the predictors of mortality and the outcomes of AC in patients hospitalized with COVID-19 in the United *** We conducted a retrospective cohort study using the National Inpatient Sample(NIS)database *** were identified with primary COVID-19 hospitalizations based on an underlying diagnosis of AC.A matched comparison cohort of COVID-19 patients without AC was identified after 1:N propensity score matching based on baseline sociodemographic characteristics and Elixhauser *** outcomes included median length of stay,median inpatient charges,and in-hospital *** outcomes included a prevalence of systemic *** A total of 1325 COVID-19 patients with AC were matched to 1135 patients without *** was no difference in median length of stay and hospital charges in COVID-19 patients with AC compared to non-AC(P>0.05).There was an increased prevalence of septic shock(5.7%vs 4.1%),ventricular fibrillation/ventricular flutter(0.4%vs 0%),atrial fibrillation(13.2%vs 8.8%),atrial flutter(8.7%vs 4.4%),first-degree atrioventricular nodal block(0.8%vs 0%),upper extremity venous thromboembolism(1.5%vs 0%),and variceal bleeding(3.8%vs 0%)in the AC cohort compared to the non-AC cohort(P<0.05).There was no difference in inpatient mortality in COVID-19 patients with non-AC compared to AC,with an odds ratio of 0.97(95%confidence interval:0.78-1.22,P=0.85).Predictors of mortality included advanced age,cardiac arrhythmias,coagulopathy,protein-calorie malnutrition,flui

关键词： Alcoholic cirrhosis COVID-19 Chronic liver disease Mortality predictors Inpatient complications

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双馈风力发电机定子绕组匝间短路故障特征提取

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热力发电 2016年第8期45卷 63-67页

作者：赵勇王路路赵祎涵 attiq ur rehman 陈玉西安热工研究院有限公司陕西西安710032 西安交通大学电气工程学院陕西西安710049

分析了双馈风力发电机定子绕组匝间短路的故障机理,建立了定子绕组匝间短路数学模型,利用MATLAB/Simulink仿真得到了发电机定子绕组匝间短路故障发生时的定子三相电流和匝间环流。研究结果表明:从定子三相电流波形中难以分辨轻微匝间短... 详细信息

分析了双馈风力发电机定子绕组匝间短路的故障机理,建立了定子绕组匝间短路数学模型,利用MATLAB/Simulink仿真得到了发电机定子绕组匝间短路故障发生时的定子三相电流和匝间环流。研究结果表明:从定子三相电流波形中难以分辨轻微匝间短路;而通过分析不同故障情况下定子电流Park矢量椭圆长半轴和短半轴的长度发现,Park矢量椭圆离心率能够灵敏反映故障并预估故障程度,因此,认为Park矢量椭圆离心率可以作为定子绕组匝间短路故障诊断的特征参量。

关键词：双馈风力发电机定子匝间短路 Park矢量椭圆离心率故障特征

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Wheat Yield Response to Foliar Fungicide Application against Leaf Rust Caused by Puccinia triticina

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Journal of Agricultural Science and Technology(A) 2017年第3期7卷 160-168页

作者： Krishna Dev Joshi Ghulam Ullah attiq ur rehman Muhammad Makky Javaid Javed Ahmad Makhdoom Hussain Angela Pacheco Ibni Amin Khalil Amanullah Baloch International Maize and Wheat Improvement Center (CIMMYT) Islamabad 44000 Pakistan Wheat Research Institute Faisalabad 38000 Pakistan International Maize and Wheat Improvement Center (CIMMYT) Texcoco Edo. de México CP 56130 Mexico Cereal Crops Research Institute Nowshera 24100 Pakistan

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Production systems and important antimicrobial resistant-pathogenic bacteria in poultry:a review

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Journal of Animal Science and Biotechnology 2023年第2期14卷 481-500页

作者： Philip H.W.Mak Muhammad attiq rehman Elijah G.Kiarie Edward Topp Moussa S.Diarra Guelph Research and Development Centre Agriculture and Agri-Food Canada(AAFC)GuelphONCanada Department of Animal Biosciences University of GuelphGuelphONCanada London Research and Development Center AAFCLondonONCanada.

Economic losses and market constraints caused by bacterial diseases such as colibacillosis due to avian pathogenic Escherichia coli and necrotic enteritis due to Clostridium perfringens remain major problems for poultry producers,despite substantial efforts in prevention and *** have been used not only for the treatment and prevention of such diseases,but also for growth ***,these practices have been linked to the selection and spread of antimicrobial resistant bacteria which constitute a significant global threat to humans,ani-mals,and the *** break down the antimicrobial resistance(AMR),poultry producers are restricting the antimicrobial use(AMU)while adopting the antibiotic-free(ABF)and organic production practices to satisfy consum-ers’***,it is not well understood how ABF and organic poultry production practices influence AMR profiles in the poultry gut *** Gram-negative(Salmonella enterica serovars,Campylobacter jejuni/coli,***)and Gram-positive(Enterococcus spp.,Staphylococcus *** ***)bacteria harboring multiple AMR determinants have been reported in poultry including organically-and ABF-raised *** this review,we discussed major poultry production systems(conventional,ABF and organic)and their impacts on AMR in some potential pathogenic Gram-negative and Gram-positive bacteria which could allow identifying issues and opportuni-ties to develop efficient and safe production practices in controlling pathogens.

关键词： Antibiotic-free Antimicrobial resistance Conventional feeding Organic Poultry

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