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Biomedical and Environmental Sciences 2015年第9期28卷 660-665页

作者： Faridah Yusof atheer awad mehde Wesen Adel Mehdi Raha Ahmed Raus Hamid Ghazali Azlina Abd Rahman Department of Biotechnology Engineering College of EngineeringInternational Islamic University Malaysia Department of Medical Analysis Health and Medical Technical College Department of Chemistry College of Sciences for WomenUniversity of Baghdad Department of Urology Hospital Tengku Ampuan Afzan Department of Pathology Hospital Tengku Ampuan Afzan

Objective Nephrolithiasis is one of the most common disorders of the urinary tract. The aim of this study was to examine a possible relationship between DNase Ⅰ/Ⅱ activity and E3 SUMO-protein ligase NSE2 in the sera of nephrolithiasis patients to evaluate the possibility of a new biomarker for evaluating kidney damage. Methods Sixty nephrolithiasis patients and 50 control patients were enrolled in a case-control study. Their blood urea, creatinine, protein levels and DNase Ⅰ/Ⅱ activity levels were measured by spectrometry. Serum NSMCE2 levels were measured by ELISA. Blood was collected from patients of the government health clinics in Kuantan-Pahang and fulfilled the inclusion criteria. Results The result indicated that mean levels of sera NSMCE2 have a significantly increase（P〈0.01） in patients compared to control group. Compared with control subjects, activities and specific activities of serum DNase Ⅰ and Ⅱ were significantly elevated in nephrolithiasis patients（P〈0.01）. Conclusion This study suggests that an increase in serum concentrations of DNase Ⅰ/Ⅱ and E3 SUMO-protein ligase NSE2 level can be used as indicators for the diagnosis of kidney injury in patients with nephrolithiasis.

关键词： Nephrolithiasis DNase Ⅰ DNase Ⅱ E3 SUMO-protein ligase NSE2 NSMCE2

Levels of antioxidant enzymes and alkaline protease from pulp and peel of sunflower

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Asian Pacific Journal of Tropical Biomedicine 2017年第6期7卷 533-537页

作者： Wesen Adel Mehdi Faridah Yusof Layla O.Farhan atheer awad mehde Raha Ahmed Raus Department of Chemistry College of Sciences for WomenUniversity of Baghdad Department of Biotechnology Engineering College of EngineeringInternational Islamic University Malaysia Department of Technical Medical Analysis College of Health and Medical TechnologyMiddle Technical University

Objective:The activity of enzymes participating in the systems of antioxidant protection was assayed in the peel and pulp of *** essential roles of proteases in food stimulate research to find other sources of the enzyme especially from non-conventional *** the present work,we study several biochemical parameters in the pulp and peel of ***:Pulp and peel of sunflower was extracted,antioxidant enzymes and nonenzymatic antioxidant were *** protease was measured and purified from pulp in ***:High carbohydrate concentration,beta-carotene,catalase and ascorbate peroxidase activities,free radical scavenging capacity and free flavonoid content were observed in the peel of ***,MDA and ceruloplasmin activities were high in the pulp of ***:The present study concluded that peel in sunflower are strong radical scavengers and can be considered as good sources of natural antioxidants for medicinal and commercial *** analysis showed that protease activity was a significantly high in the pulp compared to the peel.

关键词： Pulp sunflower Antioxidant enzymes Free radical scavenging capacity Free flavonoid content Alkaline protease

The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia

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Asian Pacific Journal of Tropical Biomedicine 2015年第6期5卷 476-482页

作者： Faridah Yusof atheer awad mehde Wesen Adel Mehdi Hamid Ghazali Azlina Abd Rahman Department of Biotechnology Engineering College of Engineering International Islamic University Malaysia Department of Medical analysis Health and Medical Technical College Department of Chemistry College of Sciences for Women University of Baghdad Department of Urology Hospital Tengku Ampuan Afzan Department of Pathology Hospital Tengku Ampuan Afzan

Objective: To verify possible associations between adenosine aminohydrolase(ADA) and AMP-aminohydrolase(AMPDA) to E3 SUMO-protein ligase NSE2(NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy ***: A total of 60 renal stones patients and 50 control were enrolled in a case-control study. The blood urea, creatinine, uric acid, protein, albumin, ADA and AMPDA were measured by colorimetric tests. The serum NSMCE2 was measured by ***: Serum ADA, AMPDA and specii c activity of enzymes showed signii cant decrease(P < 0.05) in patients with renal stones compared to control group, mean levels of sera NSMCE2 and uric acid had a signii cant increase(P < 0.01 and P < 0.05, respectively) in patients compared to control ***: The present study suggests that ADA, AMP deaminase and NSMCE2 can be used as a indicator to monitor the DNA damage and inl ammation disorders in the patients with kidney stones.

关键词： Renal stone Adenosine aminohydrolase AMP-aminohydrolase Uric acid

Study the effect of kidney stones on serum xanthine oxidase, ecto-5'-nucleotidase activity and E3 SUMO-protein ligase NSE2(NSMCE2) in Malaysian individuals

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Asian Pacific Journal of Tropical Biomedicine 2015年第8期5卷 665-668页

Objective: To verify possible relations between 5'-nucleotidase, xanthine oxidase to E3 small ubiquitin-like modifier-protein ligase non structural maintenance of chromosomes elements 2 in sera patients with kidney stones and to evaluate the possibility of a new biomarker for the evaluation of kidney damage. Methods: A sixty patients with known kidney stones who appeared the government health clinics in Kuantan–Pahang and fifty apparently healthy were taken as control group. The 5'-nucleotidase,xanthine oxidase and other biochemical parameters were measured by colorimetric tests. The serum NSMCE2 were measured by enzyme linked immunosorbent ***: The mean serum xanthine oxidase [(39.98±19.70) IU/L] and ecto-5'-nucleotidase activity(40.03±9.53 IU/L) were significantly higher than the controls' levels of(18.04 ±6.26) and(16.06 ±4.61) IU/L respectively. There were 85.00% and 83.33%, of patients with kidney stones who had abnormal ecto-5'-nucleotidase activity and uric acid respectively while xanthine oxidase activity was less sensitive 58.33%.Conclusions: The present study suggests that the increase in serum of xanthine oxidase,ecto-5'-nucleotidase activities E3 small ubiquitin-like modifier-protein ligase NSE2 concentration can be used as biomarkers for diagnosis of kidney damage in patients with kidney stone,also in developments of change DNA damage and inflammation disorders in these patients.

关键词： Kidney stones Xanthine oxidase Ecto-5’-nucleotidase E3 SUMO-protein ligase NSE2

Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients

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Asian Pacific Journal of Tropical Biomedicine 2017年第3期7卷 249-252页

作者： atheer awad mehde Faridah Yusof Wesen Adel Mehdi Raha Ahmed Raus Layla Othman Farhan Jwan Abdulmohsin Zainulabdeen Zaima Azira Zainal Abidin Hamid Ghazali Azlina Abd Rahman Department of Biotechnology Engineering College of EngineeringInternational Islamic University MalaysiaKuala Lumpur50728Malaysia Department of Technical Medical Analysis College of Health and Medical TechnologyMiddle Technical UniversityBaghdad10047Iraq Department of Chemistry College of Sciences for WomenUniversity of BaghdadBaghdad10071Iraq Department of Chemistry College of SciencesUniversity of BaghdadBaghdad10071Iraq College of Science International Islamic University MalaysiaKuantan25200Malaysia Department of Urology Hospital Tengku Ampuan AfzanKuantan25200Malaysia Department of Pathology Hospital Tengku Ampuan AfzanKuantan25200Malaysia

Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2(NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis ***: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ***: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly ***: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis.

关键词： Nephrolithiasis Peroxynitrite Nitric oxide E3 SUMO-protein ligase NSE2 Total oxidant status

A Comprehensive Review on Charging Topologies and Power Electronic Converter Solutions for Electric Vehicles

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 675-694页

作者： Abdelfatah Ali Hossam H.H.Mousa Mostafa F.Shaaban Maher A.Azzouz Ahmed S.A.awad the Department of Electrical Engineering American University of Sharjah26666 SharjahUnited Arab Emirates the Department of Electrical Engineering South Valley University83523 QenaEgypt the Department of Electrical and Computer Engineering University of WindsorWindsorON N9B 3P4 Canada Electrical Engineering Department Qatar UniversityDoha 2713Qatar Department of Electrical and Computer Engineering Sultan Qaboos UniversityMuscat123Oman

Electric vehicles(EVs)are becoming more popular worldwide due to environmental concerns,fuel security,and price *** performance of EVs relies on the energy stored in their batteries,which can be charged using either AC(slow)or DC(fast)***,EVs can also be used as mobile power storage devices using vehicle-to-grid(V2G)*** electronic converters(PECs)have a constructive role in EV applications,both in charging EVs and in ***,this paper comprehensively investigates the state of the art of EV charging topologies and PEC solutions for EV *** examines PECs from the point of view of their classifications,configurations,control approaches,and future research prospects and their impacts on power *** can be classified into various topologies:DC-DC converters,AC-DC converters,DC-AC converters,and AC-AC *** address the limitations of traditional DC-DC converters such as switching losses,size,and high-electromagnetic interference(EMI),resonant converters and multiport converters are being used in high-voltage EV ***,power-train converters have been modified for high-efficiency and reliability in EV *** paper offers an overview of charging topologies,PECs,challenges with solutions,and future trends in the field of the EV charging station applications.

关键词： Charging station charging topology electric vehicle power electronic converter vehicle-to-grid

Single nucleotide polymorphism within chromosome 8q24 is associated with prostate cancer development in Saudi Arabia

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Asian Journal of Urology 2024年第1期11卷 26-32页

作者： awad Elsid Osman Sahar Alharbi Atif Ali Ahmed Asim Ali Elbagir Pathology and Clinical Laboratory Management Department(PCLM) King Fahad Medical CityRiyadhSaudi Arabia Department of Pathology and Laboratory Medicine University of Missouri at Children's Mercy HospitalKansas CityMOUSA

Objective: Genome-wide association studies have demonstrated that single nucleotide polymorphisms (SNPs) are important risk factors for the development of prostate cancer (PCa). Preliminary studies have suggested that the incidence of PCa in Saudi males is low but is probably familial or genetically ***: To identify any possible association of SNP with PCa development in Saudi patients, we investigated a group of SNPs in Saudi PCa patients (n=85) and compared the outcomes to healthy normal controls (n=115) and nodular hyperplasia patients (n=120). DNA was extracted from paraffin-embedded formalin fixed tissue or whole blood from both patients’ groups and healthy control group. A total of thirteen SNPs were genotyped using TaqMan® minor groove binder polymerase chain reaction ***: The rs16901979A, s629242T and rs1447295A alleles were found at significantly higher frequency in PCa patients than controls (p< 0.05). The rs16901979 CA genotype was found at significantly greater frequency in PCa patients than in healthy controls (43% vs. 14%, odds ratio=4.6, p=0.0001) and benign hyperplasia group (43% vs. 25%, odds ratio=2.2, p=0.009).Conclusion: Our study has highlighted the association of rs16901979 SNP with PCa in Saudi males. Such findings have important implications in the PCa diagnosis and in screening unaffected family members of Saudi patients.

关键词： Prostatecancer Saudi Singlenucleotide polymorphism Allele

Analysis of the Drought Impact as an Extreme Climatic Event in Sudan

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Journal of Geoscience and Environment Protection 2024年第6期12卷 38-47页

作者： awad Hussien School of Atmospheric Science Nanjing University of Information Science & Technology Nanjing China

This study aimed to investigate drought as an extreme climatic event in Sudan by utilizing the Anomaly and Standard Precipitation Index (SPI). This research employed high-resolution Climate Hazards Group Infrared Precipitation with Station (CHIRPS) data to analyze the temporal and spatial distribution of rainfall in Sudan from 2001 to 2015. Notably, the analysis compared the annual average precipitation to specific drought events and calculated the Standardized Precipitation Index (SPI). The results indicate a striking frequency of drought occurrence in Sudan, with SPI values suggesting similarities between drought and wet years. It is recommended to compute the SPI for individual stations rather than rely solely on area averages. Despite the comparable SPI values between the drought and wet years, this study emphasizes the profound impact of drought as a recurring phenomenon in Sudan. These findings emphasize the urgent need for proactive drought management and mitigation strategies in Sudan to effectively address the consequences of this climatic challenge.

关键词： CHIRPS SPI Anomaly Rainfall Aridity

Diagnostic and therapeutic role of endoscopic ultrasound in liver diseases:A systematic review and meta-analysis

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World Journal of Gastroenterology 2024年第7期30卷 742-758页

作者： Eyad Gadour Abeer awad Zeinab Hassan Khalid Jebril Shrwani Bogdan Miutescu Hussein Hassan Okasha Department of Gastroenterology and Hepatology King Abdulaziz Hospital-National GuardAhsa 31982Saudi Arabia Department of Internal Medicine Faculty of MedicineZamzam University CollegeKhartoum 11113Sudan Department of Hepatogastroenterology Kasar Alainy HospitalFaculty of MedicineCairo UniversityCairo 11451Egypt Department of Internal Medicine Stockport Hospitals NHS Foundation TrustManchester SK27JEUnited Kingdom Public Health Authority Saudi Center for Disease Prevention and ControlJazan 45142Saudi Arabia Department of Clinical Infection Microbiology and ImmunologyInstitute of Infection and Global HealthSchool of Medicine and Life SciencesUniversity of LiverpoolLiverpoolUnited Kingdom Department of Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 300041Romania Advanced Regional Research Center in Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 30041Romania Department of Internal Medicine Division of Gastroenterology and HepatologyKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt

BACKGROUND In hepatology,the clinical use of endoscopic ultrasound(EUS)has experienced a notable increase in recent *** applications range from the diagnosis to the treatment of various liver ***,this systematic review summarizes the evidence for the diagnostic and therapeutic roles of EUS in liver *** To examine and summarize the current available evidence of the possible roles of the EUS in making a suitable diagnosis in liver diseases as well as the therapeutic accuracy and *** PubMed,Medline,Cochrane Library,Web of Science,and Google Scholar databases were extensively searched until October *** methodological quality of the eligible articles was assessed using the Newcastle-Ottawa scale or Cochrane Risk of Bias *** addition,statistical analyses were performed using the Comprehensive Meta-Analysis *** Overall,45 articles on EUS were included(28 on diagnostic role and 17 on therapeutic role).Pooled analysis demonstrated that EUS diagnostic tests had an accuracy of 92.4%for focal liver lesions(FLL)and 96.6%for parenchymal liver ***-guided liver biopsies with either fine needle aspiration or fine needle biopsy had low complication rates when sampling FLL and parenchymal liver diseases(3.1%and 8.7%,respectively).Analysis of data from four studies showed that EUS-guided liver abscess had high clinical(90.7%)and technical success(90.7%)without significant ***,EUS-guided interventions for the treatment of gastric varices(GV)have high technical success(98%)and GV obliteration rate(84%)with few complications(15%)and rebleeding events(17%).CONCLUSION EUS in liver diseases is a promising technique with the potential to be considered a first-line therapeutic and diagnostic option in selected cases.

关键词： Focal liver lesion Liver abscess drainage Fine needle aspiration Gastric varices Endoscopic ultrasound

The Influence of Information Technology(IT)on Accrual Accounting Adoption:The Case of the Jordanian Public Sector

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Journal of Modern Accounting and Auditing 2024年第2期20卷 40-48页

作者： Moawiah awad Alghizzawi Rosnia Masruki University of Buraimi Al BuraimiOman Universiti Sains Islam Malaysia NilaiMalaysia

Jordan is one of many countries that intends to reform its public sector by adopting accrual accounting,which is primarily carried out through the International Public Sector Accounting Standards(IPSAS)implementation plan,scheduled to be completed by *** the difficulties of adoption,this process cannot be completed without an appropriate Information Technology(IT)system capable of providing the accounting information required for this ***,this study aims to examine the influence of IT on accrual accounting adoption in the Jordanian public *** study employed the quantitative survey *** on 331 usable questionnaires,the descriptive findings showed that the use of IT in the Jordanian public sector is relevant to daily accounting transactions in general and to accrual accounting in *** regression analysis showed a positive,significant relationship between IT use and accrual accounting *** IT specialist should be able to understand the needs of public sector in adopting accrual-based *** line with today’s digitalization age,which integrates advanced technologies and numerous techniques,this study suggests that a combination of accounting and IT experts is a value added to sharpen the competitiveness of public sector *** study contributes to the extant literature in public sector,concerning the relationship between IT and accrual accounting adoption in the context of Jordan.

关键词： public sector accrual accounting adoption information technology Jordan