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Vibrations characterization in milling of low stiffness parts with a rubber-based vacuum fixture

Chinese Journal of Aeronautics 2021年第6期34卷 54-66页

作者： Antonio RUBIO-MATEOS Mikel CASUSO asuncion rivero Eneko UKAR Aitzol LAMIKIZ TECNALIA Basque Research and Technology Alliance(BRTA)Paseo Mikeletegi 7Pcirque TecnologicoE-20009 San SebastianSpain University of the Basque Country(UPV/EHU) ETTSII–Department of Mechanical EngineeringC/Alameda de Urquijo s/nE-48013 BilbaoSpain

Fixtures are a critical element in machining operations as they are the interface between the part and the *** components are responsible for the precise part location on the machine table and for the proper dynamic stability maintenance during the manufacturing *** these two features are deeply related,they are usually studied *** the one hand,diverse adaptable solutions have been developed for the clamping of different variable ***,the stability of the part has been long studied to reduce the forced vibration and the chatter effects,especially on thin parts machining operations typically performed in the aeronautic field,such as the skin panels *** present work proposes a commitment between both features by the presentation of an innovative vacuum fixture based on the use of a vulcanized rubber *** solution presents high flexibility as it can be adapted to different geometries while providing a proper damping capacity due to the viscoelastic and elastoplastic behaviour of these ***,the sealing properties of these elastomers provide the perfect combination to transform a rubber layer into a flexible vacuum ***,in order to validate the suitability of this fixture,a test bench is manufactured and tested under uniaxial compression loads and under real finish milling conditions over AA2024 part ***,a roughness model is proposed and analysed in order to characterize the part vibration sources.

关键词： AA2024 aeronautic skin Chatter Damping Finish milling Rubber characterization Vacuum clamping

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Influence of broken kernels content on soybean quality during storage

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Grain & Oil Science and Technology 2024年第2期7卷 105-112页

作者： Lazaro da Costa Correa Canizares Cesar Augusto Gaioso Newiton da Silva Timm Silvia Leticia rivero Meza Adriano Hirsch Ramos Maurício de Oliveira Everton Lutz Moacir Cardoso Elias Department of Agroindustry Science and Technology Federal University of PelotasPelotasRio Grande do Sul 96010-900Brazil Information and Communication Technological Axis Federal Institute of EducationScienceand Technology FarroupilhaCampus PanambiPanambiRio Grande do Sul 98280-000Brazil

Although it is recognized that the post-harvest system is most responsible for the loss of soybean quality,the real impact of this loss is still *** regulation allows 15%and 30%of broken soybean for group I and group II(quality groups),***,the industry is not informed about the loss in the quality parameters of soybeans and its impacts during long-term ***,the objective was to evaluate the effect of the breakage kernel percentage of soybean stored for 12 *** of 15% of breakage kernels did not affect soybean ***,content of 30% of breakage kernels affected significantly soybean quality,which was evidenced by the increase of up to 75% in moldy soybeans,72% in acidity,50% in leached solids,27% in electrical conductivity,and the decrease of up to 12% in soluble protein,6.4% in germination and 3.5% in thousand kernel weight after 8 months of *** the legislation establishes a percentage limit,it is recommended to store soybeans with up to 15% breakage *** the contrary,values higher than that can cause a significant reduction in soybean quality,resulting in commercial losses.

关键词： Soybean quality Breakage kernels Storage problems Grain defects Quality parameters

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Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1644-1664页

作者： Gabriela Seplovich Yazan Bouchi Juan Pablo de rivero Vaccari Jennifer C.Munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref Kevin K.Wang J.Adrian Tyndall Binu Tharakan Firas Kobeissy Department of Surgery Morehouse School of MedicineAtlantaGAUSA Department of Neurobiology Center for NeurotraumaMultiomics&Biomarkers(CNMB)Neuroscience InstituteMorehouse School of MedicineAtlantaGAUSA Department of Neurological Surgery and the Miami Project to Cure Paralysis University of Miami Miller School of MedicineMiamiFLUSA Division of Pediatric Critical Care Department of PediatricsUniversity of Miami Miller School of MedicineMiamiFLUSA Department of Pediatrics Emory UniversityAtlantaGAUSA Department of Neurosurgery Children’s Healthcare of AtlantaAtlantaGAUSA Department of Chemistry and Biochemistry Texas Tech UniversityLubbockTXUSA Morehouse School of Medicine AtlantaGAUSA

Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of neuroinflammation includes the pathologic hyperphosphorylation of tau protein, an endogenous microtubule-associated protein that protects the integrity of neuronal cytoskeletons. Tau hyperphosphorylation results in protein misfolding and subsequent accumulation of tau tangles forming neurotoxic aggregates. These misfolded proteins are characteristic of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease and can lead to downstream neuroinflammatory processes, including assembly and activation of the inflammasome complex. Inflammasomes refer to a family of multimeric protein units that, upon activation, release a cascade of signaling molecules resulting in caspase-induced cell death and inflammation mediated by the release of interleukin-1β cytokine. One specific inflammasome, the NOD-like receptor protein 3, has been proposed to be a key regulator of tau phosphorylation where it has been shown that prolonged NOD-like receptor protein 3 activation acts as a causal factor in pathological tau accumulation and spreading. This review begins by describing the epidemiology and pathophysiology of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease. Next, we highlight neuroinflammation as an overriding theme and discuss the role of the NOD-like receptor protein 3 inflammasome in the formation of tau deposits and how such tauopathic entities spread throughout the brain. We then propose a novel framework linking traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease as inflammasomedependent pathologies that exist along a temporal continuum. Finally, we discuss potential therapeutic targets that may intercept this pathway and ultimately minimize long-term neurological decline.

关键词： Alzheimer's disease caspase-1 chronic traumatic encephalopathy inflammasomes neurodegeneration neuroinflammation NLRP1 NLRP3 pyroptosis tauopathy traumatic brain injury

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Multi-tissue transcriptomics of a unique monozygotic discordant twin case of severe progressive osseous heteroplasia

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Genes & Diseases 2024年第3期11卷 22-25页

作者： Alberto Gomez-Carballa Maria Jose Curras-Tuala Sara Pischedda Miriam Cebey-Lopez Jose Gomez-Rial Irene rivero-Cale Jacobo Pardo-seco Xabier Bello Sandra Viz-Lasheras Antonio Justicia-Grande Julian Montoto-Louzao Alba Camino-Mera Isabel Ferreiros-Vidal Maximo Fraga Jose RAntunez Rodolfo Gomez Federico Martinon-Torres Antonio Salas Genetics Vaccines and Infections Research Group(GENVIP)Instituto de Investigacion Sanitaria de SantiagoSantiagode CompostelaGalicia 15706Spain Translational Pediatrics and Infectious Diseases Department of PediatricsHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Laboratorio de Inmunologia Servicio de Andlisis ClinicosHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Unidade de Xenetica Instituto de Ciencias Forenses(INCIFOR)Facultade de MedicinaUniversidade de Santiago de Compostelaand GenPoB Research GroupInstituto de Investigacion SanitariaHospital Clinico Universitario de Santiago de CompostelaServicio Galego de Saude(SERGAS)Galicia 15706Spain Musculoskeletal Pathology Group Instituto de Investigacion Sanitaria de SantiagoServicio Galego de Saude(SERGAS)Santiago de CompostelaGalicia 15706Spain Department of Pathology Hospital Clinico Universitario de Santiago de Compostela(SERGAS)Galicia 15706Spain Unidad Integrada de BiobancosBiomodelos 3D y Modelos Animales IDIS(lnstituto de Investigacion Sanitaria de Santiagode Compostela)Galicia15706Spain Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias(CIBER-ES) MadridSpain

Progressive osseous heteroplasia(POH)is an ultra-rare autosomal dominant disabling disorder characterized by heterotopic ossification(HO).It is caused by heterozygous inactivating mutations in the GNAS(guanine nucleotide-binding protein alpha-stimulating activity polypeptide)***,the molecular mechanisms underlying HO remain poorly *** a treatment for POH is not yet available,the identification of the mechanisms driving POH in affected tissues using gene expression may be of great help to underestand the molecular basis of POH and develop new therapeutic approaches.

关键词： stimulating driving asi

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乡村公共数字文化服务标准化推进机理

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图书情报研究 2024年第2期17卷 26-38页

作者：田一王锰连忻杰 Amalia Isabel rivero Chávez 江苏大学科技信息研究所镇江212013 曼萨尼约市历史档案馆古巴曼萨尼约市87510

[目的/意义]乡村公共数字文化服务在国家层面已然得到政策和法律保障,基本公共文化服务体系初具成效。本研究聚焦乡村公共数字文化服务标准化。[方法/过程]以我国三个公共文化服务体系示范区乡镇服务点的实地调研数据为依据,深入了解乡... 详细信息

[目的/意义]乡村公共数字文化服务在国家层面已然得到政策和法律保障,基本公共文化服务体系初具成效。本研究聚焦乡村公共数字文化服务标准化。[方法/过程]以我国三个公共文化服务体系示范区乡镇服务点的实地调研数据为依据,深入了解乡村公共数字文化服务标准化状况。[结果/结论]从推进主体、推进内容、推进方式三方面构建乡村公共数字文化服务标准化机制的模型,“政府驱动型”、“服务增效型”、“基础保障型”的三重应用模式为政府以标准化完善现代化公共文化服务体系提供了有效参考。

关键词：公共数字文化服务数字乡村服务标准扎根理论

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The affairs of the Falco

The affairs of the Falco

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作者： Melissa rivero.

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Electroconvulsive therapy,catatonia,deep vein thrombosis and anticoagulant treatment:a case report

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General Psychiatry 2021年第6期34卷 73-76,I0008,I0009页

作者： Ana Pérez-Balaguer Irene Sánchez-rivero Department of Psychiatry Hospital Universitario Puerta de Hierro MajadahondaMajadahondaSpain

Electroconvulsive therapy(ECT)is considered an effective treatment for pharmacotherapy-resistant severe mental *** is a complex syndrome characterised by important psychomotor *** vein thrombosis(DVT)and pulmonary embolism(PE)are frequent side effects of prolonged immobility in catatonic ***,it is important to resolve the catatonia as soon as *** is the most effective therapy available and is generally considered a safe ***,its use in patients with DVT or PE and anticoagulant treatment remains *** describe a case of a woman in her 40s with a previous diagnosis of bipolar disorder and dysfunctional personality *** was hospitalised with persecutory and reference delusions,high emotional lability,anxiety,somatisation and regressive *** later developed catatonic *** progress was achieved after a month of hospitalisation,despite several pharmacological *** suffered multiple complications of prolonged bedding,such as an extensive DVT of the left common femoral,the external iliac and the common iliac *** was conducted under treatment with *** the third administration,she showed *** major bleeding or PE was *** safety of ECT while receiving anticoagulant therapy has been documented,though dosage and type of anticoagulant must be *** of DVT(proximal or distal)may be an important topic to take into *** report provides further evidence about the efficacy and safety of undergoing ECT in the context of concomitant serious medical conditions,such as DVT and anticoagulant therapy administration.

关键词： dosage treatment diagnosis

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In vivo optical quality of posterior-chamber phakic implantable collamer lenses with a central port

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Eye and Vision 2021年第5期8卷 295-302页

作者： Robert Montés-Micó Francisco Pastor-Pascual Enrique Artiaga-Elordi Ramón Ruiz-Mesa Pedro Tañá-rivero Optics and Optometry&Vision Sciences Department University of Valenciac/o Dr Moliner 5046100 ValenciaSpain Oftalvist Clinic ValenciaSpain

Background:The aim of this review is to summarize the optical quality results in patients following the implantation of the V4c implantable collamer lens with a central port(ICL,STAAR Surgical Inc.).Main text:A literature search in several databases was carried out to identify those publications,both prospective,retrospective and/or comparative with other refractive surgery procedures,reporting optical outcomes of patients who were implanted with the V4c ICL model.A total of 17 clinical studies published between 2012 and 2021 were included in this review.A detailed analysis of the available data was performed including number of eyes,follow-up and preoperative spherical ***,the review focused on several optical parameters including higher-order aberrations(HOAs),modulation transfer function(MTF)cut-off frequency and Strehl *** review encompassed a total of 817 eyes measured using different optical devices based on Hartmann-Shack,retinal image quality measurement and ray-tracing technologies at different ***:The outcomes found in this review lead us to conclude that the ICL V4c model provides good optical quality,by means of different metrics,when implanted.

关键词： Implantable collamer lens Phakic Optical quality Higher order aberrations Modulation transfer function

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Successful treatment with hysteroscopy for infertility due to isthmocele and hydrometra secondary to cesarean section: A case report

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World Journal of Clinical Cases 2019年第6期7卷 753-758页

作者： Luis Pablo López rivero Miguel Jaimes Felipe Camargo Esther López-Bayghen Instituto de Infertilidad y Genética México SC Departamento de Toxicología Centro de Investigación de Estudios

BACKGROUND An isthmocele is a scar defect in the uterine wall due to a cesarean section. Its prevalence is unknown,but it has been associated with secondary ***,we present a case where the patient suffered from an isthmocele that was associated with persistent hydrometra,which developed during in vitro *** SUMMARY The patient underwent hysteroscopic surgery,which successfully resolved the isthmocele as well as the hydrometra. Afterward,two high-quality,euploid embryos,determined by morphological assessment and pre-implantation genetic diagnostic testing,were transferred. This resulted in uterine pregnancy,as determined byserum β-human chorionic gonadotropin levels on day 14(180 m U/mL) and ultrasound-confirmed presence of a gestational sac with a positive embryocardia at week 6. The pregnancy reached 36 wk without any complications,and the product was born in good health. We report a successful isthmocele treatment in a patient with secondary infertility,in which the isthmocele was the cause of persistent *** Hydrometra caused by secondary cesarean is an infertility factor,which can be corrected by hysteroscopy plus ablation of the isthmocele.

关键词： In vitro fertilization Isthmocele Hydrometra Case report

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Wide field-of-view metalens: a tutorial

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Advanced Photonics 2023年第3期5卷 1-21页

作者： Fan Yang Mikhail YShalaginov Hung-I Lin Sensong An Anu Agarwal Hualiang Zhang Clara rivero-Baleine Tian Gu Juejun Hu Massachusetts Institute of Technology Department of Materials Science and EngineeringCambridgeMassachusettsUnited States University of Massachusetts Lowell Department of Electrical and Computer EngineeringLowellMassachusettsUnited States Lockheed Martin Corporation OrlandoFloridaUnited States Massachusetts Institute of Technology Materials Research LaboratoryCambridgeMassachusettsUnited States

Wide field-of-view(FOV)optics are essential components in many optical systems,with applications spanning imaging,display,sensing,and beam *** refractive wide FOV optics often involve multiple stacked lenses,resulting in large size and weight as well as high *** lenses or metalenses promise a viable solution to realizing wide FOV optics without complex lens *** review the various architectures of wide FOV metalenses,elucidate their fundamental operating principles and design trade-offs,and quantitatively evaluate and contrast their imaging *** applications enabled by wide FOV metasurface optics are also discussed.

关键词： metasurface lens imaging field of view aberration

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