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AN IMPROVED HARDY'S INEQUALITY

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Acta Mathematica Scientia 2013年第5期33卷 1382-1386页

作者： assal miloud Rahmouni ATEF Department of Mathematics Faculty of Science King Abdulaziz University Department of Mathematics Faculty of Sciences of Bizerte University of Carthage

In this paper we shall extend Hardy＇s inequality associated with Fourier trans- form to the strip n（2-p） ≤σ〈 n＋p（N＋ 1） where N = [n（1/p- 1）], the greatest integer not exceeding n（1/p - 1）.

关键词： Hardy's space Hardy's inequality

IL-6-deficient Mice Are Susceptible to Ethanol-induced Hepatic Steatosis:IL-6 Protects against Ethanol-induced Oxidative Stress and Mitochondrial Permeability Transition in the Liver

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Cellular & Molecular Immunology 2004年第3期1卷 205-211页

作者： Osama El-assal Won-HoKim SvetlanaRadaeva Section on Liver Biology Laboratory of Physiologic StudiesNational Institute on Alcohol Abuse and AlcoholismNational Institutes of HealthBethesdaMD 20892USA.

Interleukin-6(IL-6)-deficient mice are prone to ethanol-induced apoptosis and steatosis in the liver;however, the underlying mechanism is not fully *** dysfunction caused by oxidative stress is an early event that plays an important role in the pathogenesis of alcoholic liver ***,we hypothesize that the protective role of IL-6 in ethanol-induced liver injury is mediated via suppression of ethanol-induced oxidative stress and mitochondrial *** test this hypothesis,we examined the effects of IL-6 on ethanol-induced oxidative stress,mitochondrial injury,and energy depletion in the livers of IL-6(-/-)mice and hepatocytes from ethanol-fed *** consumption leads to stronger induction of malondialdehyde(MDA) in IL-6(-/-)mice compared to wild-type control mice,which can be corrected by administration of *** vitro, IL-6 treatment prevents ethanol-mediated induction of reactive oxygen species(ROS),MDA,mitochondrial permeability transition(MPT),and ethanol-mediated depletion of adenosine triphosphate(ATP)in hepatocytes from ethanol-fed *** of IL-6 in vivo also reverses ethanol-induced MDA and ATP depletion in ***,IL-6 treatment induces metallothionein protein expression,but not superoxide dismutase and glutathione peroxidase in cultured *** conclusion,IL-6 protects against ethanol-induced oxidative stress and mitochondrial dysfunction in hepatocytes via induction of metailothionein protein expression,which may account for the protective role of IL-6 in alcoholic liver *** & Molecular Immunology.2004;1(3):205-211.

关键词： IL-6 alcoholic liver injury oxidative stress mitochondria metallothionein

Aging effect and test-retest reliability of the sinusoidal harmonic acceleration test and velocity step test using nanotorque rotatory chair

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Journal of Otology 2023年第3期18卷 125-131页

作者： Nourhan Ghoraba Samir assal Doaa Elmoazen Audiovestibular Medicine Unit Otorhinolaryngology DepartmentFaculty of MedicineAlexandria UniversityEgypt

Introduction:Rotatory chair testing has been used to evaluate horizontal canal *** used tests include sinusoidal harmonic acceleration test(SHAT)and velocity step test(VST).Objectives:Assessment of age effect on the SHAT and VST and assessment of test-retest reliability of the parameters of those two ***:A prospective study was performed on 100 subjects with no ear or vestibular complaints and normal vestibular *** were divided into two groups;Group A:below 50 years of age and Group B:50 years of age or *** was presented at frequencies 0.02,0.04,0.08,0.16,0.32,0.64 Hz with a peak velocity of 60°/*** was performed using a maximum velocity of 100°/s with acceleration and deceleration of 200°/*** subjects were tested twice to assess ***:Study participants ranged in age from 20 to 67 *** group A,the mean age was30.92±7.31 and 55.36±4.61 for group *** significant differences were found in SHAT parameters between the two *** well,there was no significant difference in VST per-rotatory time constant,however,post-rotatory time constant was significantly longer for Group B(P value<0.05).Intraclass correlation coefficient(ICC)values showed moderate to good reliability(ICC 0.5800.818)for SHAT parameters for the lower frequencies and indicated moderate reliability for VST time constant(ICC 0.5090.652).Conclusions:Age has no significant effect on the parameters of SHAT and ***-retest reliability is generally good for both tests.

关键词： Rotatory chair testing Sinusoidal harmonic acceleration test Velocity step test Age effect Test-retest reliability

Why and How Often Is Revision Surgery Necessary after First Metatarsophalangeal Joint Arthrodeses? A Cohort of 120 Consecutive Cases

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Open Journal of Orthopedics 2021年第8期11卷 221-232页

作者： Lisca Drittenbass Halah Kutaish Leow Voon Chin Richard Stern Mathieu assal Centre for Surgery of the Foot & Ankle Hirslanden Clinique La Colline Geneva Switzerland Faculty of Medicine Geneva University Geneva Switzerland

Background: Little is known about the rate and reasons for revision after primary Metatarsophalangeal (MTP1) arthrodesis with the latest implants. While it is commonly assumed that nonunion accounts for most reoperations, we hypothesized that malposition is the leading cause of revision. The aim of this study was to determine the rate and reasons for revision after MTP1 arthrodesis using cup- and cone-reamers and the latest locking plate technology. Method: Between 2015 and 2017, 120 consecutive MTP1 fusions in 114 patients were performed with a low profile, pre-contoured titanium dorsal locking plate and a plantar metatarsophalangeal screw. The rate and reasons for revision within a minimum one-year follow-up period (average 16 months [12 - 26]) after index procedures were documented

miR-34a: Multiple Opposing Targets and One Destiny in Hepatocellular Carcinoma

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Journal of Clinical and Translational Hepatology 2016年第4期4卷 300-305页

作者： Radwa Alaa Yacoub Injie Omar Fawzy Reem Amr assal Karim Adel Hosny Abdel-Rahman Nabawy Zekri Gamal Esmat Hend Mohamed El Tayebi Ahmed Ihab Abdelaziz Pharmaceutical Biology Department Faculty of Pharmacy and Biotechnology German University in Cairo Cairo Egypt pharmacology and Toxicology Department Faculty of Pharmacy and Biotechnology German University in Cairo Cairo Egypt Department of General Surgery Faculty of Medicine Cairo University Cairo Egypt Virology and Immunology Cancer Biology Department National Cancer Institute Cairo University Cairo Egypt Department of Endemic Medicine and Hepatology Cairo University Cairo Egypt pharmacology and Toxicology Department Faculty of Pharmacy and Biotechnology German University in Cairo Cairo Egypt School of Medicine New Giza University Cairo Egypt

Background and Aims:The role of miR-34a in hepatocellular carcinoma (HCC) is controversial and several unresolved issues remain,including its expression pattern and relevance to tumor etiology,tumor stage and prognosis,and finally,its impact on ***:miR-34a expression was assessed in hepatitis C virus (HCV)-induced non-metastatic HCC tissues by ***-7 cells were transfected with miR-34a mimics and the impact of miR-34a was examined on 84 pro-apoptotic/anti-apoptotic genes using PCR array;its net effect was tested on cell viability via ***:miR-34a expression was up-regulated in HCC ***,miR-34a induced a large set of pro-apoptotic/anti-apoptotic genes,with a net result of triggering apoptosis and repressing cell ***:HCC-related differential expression of miR-34a could be etiology-based or stage-specific,and low expression of miR-34a may predict poor *** study's findings also emphasize the role of miR-34a in apoptosis.

关键词： MicroRNA Hepatocellular carcinoma Apoptosis PCR array.

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可以控制刷牙时间的牙膏

日用化学品科学 1981年第3期 46-48页

作者： Jacqus assal 李焕珍

发明范围本发明与牙膏含有的物质有关,按照预定的刷牙时间,牙膏的颜色发生变化,因而,可以控制刷牙时间。近来,牙齿科学领域的研究清楚地表明,刷牙时间的作用占优势,而牙膏的化学作用似乎是次要的,因此可以断定牙齿的机械清洁和膏体的摩... 详细信息

发明范围本发明与牙膏含有的物质有关,按照预定的刷牙时间,牙膏的颜色发生变化,因而,可以控制刷牙时间。近来,牙齿科学领域的研究清楚地表明,刷牙时间的作用占优势,而牙膏的化学作用似乎是次要的,因此可以断定牙齿的机械清洁和膏体的摩擦是有重要作用

关键词：牙膏 pH 柠檬酸盐缓冲剂

Sequential Analysis in the Identification of 3rd Order System Tract in the Abidjan Margin

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Open Journal of Applied Sciences 2024年第6期14卷 1474-1489页

作者： Blandine Akissi Egoran N’guessan Donald Ahoure Fori Yao Paul assalé Sylvain Mondé Loukou Victor N’da UFR Marine Sciences San Pedro University San Pedro Cte dIvoire UFR of Sciences and Technologies Alassane Ouattara Bouak Laboratory of Plant Biology and Earth Sciences Bouak Cte dIvoire UFR/STRM Flix Houphout Boigny de Cocody Abidjan Cte dIvoire PETROCI Consultant at the Center for Analysis and Research Department of Sequential Stratigraphy Abidjan Cte dIvoire

The use of sequential stratigraphy concept, based on well logs, sedimentology, and biostratigraphy, has shed light on the complex mechanisms controlling sedimentary accumulations. Consequently, identifying these mechanisms allows us to predict the hydrocarbon generation potential of source rocks. In the Ivorian offshore sedimentary basin, certain studies have contributed to understanding and characterizing the petroleum system. However, these previous works did not integrate biostratigraphic data to highlight sedimentary facies. This study, conducted on two wells in the Abidjan margin, is crucial as it helps us comprehend the geometry of fossil sediments in relation to sea level variations. It will also aid in reconstructing the basin-filling history and predicting the distribution of rocks capable of trapping oil, determining lowstand systems tracts (reservoir rocks), transgressive systems tracts, and highstand systems tracts (cap rocks). Lithological analysis revealed predominantly clayey sedimentation with sandy layers. Well log data facilitated the delineation of formation boundaries and highlighted reservoirs consisting of sands, sandstones, limestones, and occasionally intercalated shales. Integrating these analysis results with biostratigraphic interpretations based on foraminifera and palynomorphs revealed that the traversed formations were deposited in a transitional environment ranging from Coniacian to Maastrichtian ages. Applying sequential stratigraphy concept from well logging resolved dating issues encountered in microfossil-poor or microfossil-free zones. The results of the Coniacian-Maastrichtian age sequential subdivision were aligned with the chart.

关键词： Sequence Stratigraphy Systems Tracts Senonian Côte d’Ivoire

Reliability Study of a New Electromechanical Device Designed to Measure the Relative Dorsal Mobility of the First Ray of the Foot

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Open Journal of Orthopedics 2022年第10期12卷 383-392页

作者： Nils Reymond Quentin Praz Spyridon Schoinas Navindravadhanam Sockalingam Antoine Acker Victor Dubois-Ferrière Philippe Passeraub Mathieu assal Centre assal for Foot and Ankle Surgery Clinique La Colline Geneva Switzerland Institute of Industrial Technologies and Sciences University of Applied Sciences and Arts Western Switzerland (HES-SO Geneva/HEPIA) Geneva Switzerland

Introduction: A new electromechanical instrument has been developed to measure relative dorsal mobility of the first ray in an objective and reliable way by simulating ground reaction forces during gait. This device equally applies a standardized, electronically controlled, and precise force under the first metatarsal head M1 as well as under the heads of the lesser metatarsals M2 to M5. The relative dorsal mobility between these two bearings is then measured. The purpose of this study is to assess the intra- and inter-examiners reliabilities of the measurements obtained with this device. Methods: The protocol included two examiners and 36 feet (18 volunteers with healthy feet and no history of forefoot disorders). A total of nine measurements were performed on each foot separated into three sets of three trials for the assessment of inter-rater and intra-rater reliability. For this purpose, the interclass correlation coefficient (ICC), the error of measurement (SEM) and the Bland and Altman (B&A) graphical analysis were computed. Results: Excellent ICC values (≥0.91) were obtained with the novel device for inter-rater and intra-rater reliability when using the FRRM calculation. The B&A analysis presented a bias between examiners of -0.25 mm ranging from -1.66 to 1.18 mm. Conclusion: This study demonstrated the capability of the developed device to reliably measure the relative dorsal mobility of the first ray of the foot. This is a promising first step for further studies to better understand, qualify and quantify first ray hypermobility.

关键词： First Ray Dorsal Mobility Instability Hypermobility Medical Device Reliability Study Foot

Postoperative Mechanical Axis Alignment and Components Position after Conventional and Patient-Specific Total Knee Arthroplasty

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Open Journal of Orthopedics 2016年第8期6卷 253-258页

作者： Mohamed Mosa Mohamed Maher A. El assal Ahmed M. Abdel Aal Yaser E. Khalifa Mahmoud A. Hafez Orthopaedic Department Alazhar University (Assiut Branch) Assiut Egypt Orthopaedic Department Assiut University Assiut Egypt Orthopaedic Department October 6 University Cairo Egypt

Introduction: Accurate postoperative alignment and implant positioning are determinant factors for successful total knee arthroplasty (TKA). Patient-specific template (PST) is a technique that uses computer technology for the planning, deigning and production of cutting guides. This study aims to compare PST to conventional technique in terms of mechanical axis alignment and component positioning. Patients and method: 109 TKA were performed for 78 patients in 2 groups. Group A included 69 conventional TKA in 55 patients and Group B included 40 patient-specific TKA in 23 patient. Postoperative long-film X-rays were done for all patients to observe the mechanical axis, anatomical axis, lateral distal femoral mechanical angle and medial proximal tibial angle. Results: No statistically significant difference was found between the two groups regarding alignment or component positioning. Conclusion: Both techniques have shown similar results in restoring the mechanical axis and alignment after TKA. However, PST had the advantages of reduced blood loss and shorter operative time.

关键词： Total Knee Arthroplasty Patient-Specific Templates Conventional TKA Mechanical Axis Limb Alignment Component Position