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Recent advances in the diagnosis and treatment of acute myocardial infarction

World Journal of Cardiology 2015年第5期7卷 243-276页

作者： Koushik Reddy asma khaliq Robert J Henning Department of Medicine James A Haley Veterans Administration Hospital and the University of South Florida College of Medicine

The Third Universal Definition of Myocardial Infarction(MI) requires cardiac myocyte necrosis with an increase and/or a decrease in a patient's plasma of cardiac troponin(cT n) with at least one cT n measurement greater than the 99 th percentile of the upper normal reference limit during:(1) symptoms of myocardialischemia;(2) new significant electrocardiogram(ECG) ST-segment/T-wave changes or left bundle branch block;(3) the development of pathological ECG Q waves;(4) new loss of viable myocardium or regional wall motion abnormality identified by an imaging procedure; or(5) identification of intracoronary thrombus by angiography or *** infarction,when diagnosed,is now classified into five *** of a rise and a fall of troponin are essential to the diagnosis of acute ***,high sensitivity troponin assays can increase the sensitivity but decrease the specificity of MI *** ECG remains a cornerstone in the diagnosis of MI and should be frequently repeated,especially if the initial ECG is not diagnostic of *** have been significant advances in adjunctive pharmacotherapy,procedural techniques and stent technology in the treatment of patients with *** routine use of antiplatelet agents such as clopidogrel,prasugrel or ticagrelor,in addition to aspirin,reduces patient morbidity and *** coronary intervention(PCI) in a timely manner is the primary treatment of patients with acute ST segment elevation *** eluting coronary stents are safe and beneficial with primary coronary *** with direct thrombin inhibitors during PCI is non-inferior to unfractionated heparin and glycoprotein Ⅱb/Ⅲa receptor antagonists and is associated with a significant reduction in *** intra-coronary use of a glycoprotein Ⅱb/Ⅲa antagonist can reduce infarct ***- and post-conditioning techniques can provide additional ***,the incidence and mortality due to MI continues to be high d

关键词： Myocardial necrosis Type 1-5 myocardial infarctions Troponin assays Percutaneous coronary intervention Fibrinolytic therapy Thienopyridines Cardioprotection Bone marrow stem cells Cardiac stem cells

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Energy and flux measurements of laser-induced silver plasma ions by using Faraday cup

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Plasma Science and Technology 2021年第8期23卷 188-198页

作者： Muhammad Usman Aslam BHATTI Shazia BASHIR asma HAYAT khaliq MAHMOOD Rana AYUB Mubashir JAVED Muhammad Shahzad KHAN Centre for Advanced Studies in Physics(CASP) GC UniversityLahore 54000Pakistan

Silver(Ag)plasma has been generated by employing Nd:YAG laser(532 nm,6 ns)laser *** energy and flux of ions have been evaluated by using Faraday cup(FC)using time of flight(TOF)*** dual peak signals of fast and slow Ag plasma ions have been *** energy and flux of fast and slow ions tend to increase with increasing irradiance from 7 GW cm-2 to 17.9 GW cm-2 at all distances of FC from the target *** a decreasing trend of energies and flux of ions has been observed with increasing distance of FC from the *** maximum value of flux of the fast component is21.2×10^(10) cm^(-2),whereas for slow ions the maximum energy and flux values are 8.8 keV,8.2×10^(10) cm^(-2) *** the analysis of plume expansion dynamics,the angular distribution of ion flux measurement has also been *** overall analysis of both spatial and angular distributions of Ag ions revealed that the maximum flux of Ag plasma ions has been observed at an optimal angle of~15°.In order to confirm the ion acceleration by ambipolar field,the self-generated electric field(SGEF)measurements have also been performed by electric probe;these SGEF measurements tend to increase by increasing laser *** maximum value of 232 V m^(-1) has been obtained at a maximum laser irradiance of 17.9 GW cm^(-2).

关键词： laser ablation laser-induced plasma ions Faraday cup time of flight measurements self-generated electric field angular distribution

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Investigation of secondary phases and tensile strength of nitrogen-containing Alloy 718 weldment

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International Journal of Minerals,Metallurgy and Materials 2020年第9期27卷 1259-1268页

作者： Behrooz Nabavi Massoud Goodarzi Abdul khaliq Khan School of Metallurgy and Materials Engineering Iran University of Science and TechnologyTehran ***Iran Department of Mechanical Engineering Manitoba Institute for MaterialsUniversity of ManitobaWinnipeg R3T 2N2Canada

The influence of nitrogen content on the precipitation of secondary phases and the tensile strength of Alloy 718 during gas tungstenarc welding was investigated. Various types of precipitates were characterized using scanning electron microscopy and transmission electronmicroscopy. The results showed that in the fusion zone, the volume fraction of Nb-rich phases such as Laves, (Nb,Ti)C, and δ phases, as wellas Ti-rich phases such as (Ti,Nb)CN and (Ti,Nb)N, increased with increase in the nitrogen content due to the microsegregation of Nb and Tiwithin interdendritic areas. Nitrogen was also found to decrease the size of γ′′ particles within γ dendrites. For precipitates in the partiallymelted zone, constitutional liquation was observed for both (Nb,Ti)C and (Ti,Nb)N particles. Based on the results of tensile tests, the weld containing0.015wt% nitrogen exhibited the highest ultimate tensile strength (UTS), whereas more addition of nitrogen led to a decrease in both theUTS and yield strength due to the increased content of brittle Laves phases and decreased size of γ′′.

关键词： nitrogen secondary phases gas tungsten arc welding tensile strength Alloy 718

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A Split-Step Predictor-Corrector Method for Space-Fractional Reaction-Diffusion Equations with Nonhomogeneous Boundary Conditions

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Communications on Applied Mathematics and Computation 2019年第4期1卷 525-544页

作者： Kamran Kazmi Abdul khaliq Department of Mathematics University of Wisconsin OshkoshOshkoshWI 54901USA Department of Mathematical Sciences and Center for Computational Sciences Middle Tennessee State UniversityMurfreesboroTN 37132USA

A split-step second-order predictor-corrector method for space-fractional reaction-diffusion equations with nonhomogeneous boundary conditions is presented and analyzed for the stability and *** matrix transfer technique is used for spatial discretization of the *** method is shown to be unconditionally stable and second-order *** experiments are performed to confirm the stability and secondorder convergence of the *** split-step predictor-corrector method is also compared with an IMEX predictor-corrector method which is found to incur oscillatory behavior for some time *** method is seen to produce reliable and oscillatioresults for any time step when implemented on numerical examples with nonsmooth initial *** also present a priori reliability constraint for the IMEX predictor-corrector method to avoid unwanted oscillations and show its validity numerically.

关键词： Fractional Laplacian Space-fractional reaction diffusion equations Non-homogeneous boundary conditions Matrix transfer technique Predictor-corrector method

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SDN-based intrusion detection system for IoT using deep learning classifier (IDSIoT-SDL)

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CAAI Transactions on Intelligence Technology 2021年第3期6卷 281-290页

作者： Azka Wani Revathi S Rubeena khaliq Department of Computer Applications Crescent B S Abdur Rahman Institute of Science and TechnologyChennaiIndia Department of Computer Science and Engineering Crescent B S Abdur Rahman Institute of Science and TechnologyChennaiIndia Department of Mathematics Crescent B S Abdur Rahman Institute of Science and TechnologyChennaiIndia

The participation of ordinary devices in networking has created a world of connected devices *** Internet of Things(IoT)includes heterogeneous devices from every *** are no definite protocols or standards for IoT communication,and most of the IoT devices have limited *** a complete security measure for such devices is a challenging task,yet *** lightweight security solutions have surfaced lately for *** lightweight security protocols are unable to provide an optimum protection against prevailing powerful threats in cyber *** is also hard to deploy any traditional security protocol on resource-constrained IoT ***-defined networking introduces a centralized control in computer *** has a programmable approach towards networking that decouples control and data *** SDN-based intrusion detection system is proposed which uses deep learning classifier for detection of anomalies in *** proposed intrusion detection system does not burden the IoT devices with security *** proposed work is executed on the simulated *** results of the simulation test are evaluated using various matrices and compared with other relevant methods.

关键词： IoT classifier system

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Two-dimensional investigation of characteristic parameters and their gradients for the self-generated electric and magnetic fields of laser-induced zirconium plasma

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Plasma Science and Technology 2024年第5期26卷 138-155页

作者： Tayyaba SAJID Shazia BASHIR Mahreen AKRAM Maira RAZZAQ khaliq MAHMOOD Centre for Advanced Studies in Physics Institute of PhysicsGovernment College University LahoreLahore 54000Pakistan Department of Physics Institute of PhysicsGovernment College University LahoreLahore 54000Pakistan

Two-dimensional diagnosis of laser-induced zirconium(Zr)plasma has been experimentally performed using the time-of-flight method by employing Faraday cups in addition to electric and magnetic *** characteristic parameters of laser-induced Zr plasma have been evaluated as a function of different laser irradiances ranging from 4.5 to 11.7 GW cm-2 at different axial positions of 1–4 cm with a fixed radial distance of 2 cm.A well-supporting correlation between the plume parameters and the laser-plasma-produced spontaneous electric and magnetic(E and B)fields was *** measurements of the characteristic parameters and spontaneously induced fields were observed to have an increasing trend with the increasing laser ***,when increasing the spatial distance in both the axial and radial directions,the plasma parameters(electron/ion number density,temperature and kinetic energy)did not show either continuously increasing or decreasing trends due to various kinetic and dynamic processes during the spatial evolution of the ***,the E and B fields were observed to be always diffusing away from the *** radial component of electron number densities remained higher than the axial number density component,whereas the axial ion number density at all laser irradiances and axial distances remained higher than the radial ion number *** higher axial self-generated electric field(SGEF)values than radial SGEF values are correlated with the effective charge-separation mechanism of electrons and *** generation of a self-generated magnetic field is observed dominantly in the radial direction at increasing laser irradiance as compared to the axial one due to the deflection of fast-moving electrons and the persistence of two-electron temperature on the radial axis.

关键词： Faraday cup axial and radial expansion space-charge effect laser-induced zirconium plasma two-electron temperature distribution self-generated electric and magnetic fields

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Recognizing production options for pearl millet in Pakistan under changing climate scenarios

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Journal of Integrative Agriculture 2017年第4期16卷 762-773页

作者： asmat Ullah Ashfaq Ahmad Tasneem khaliq Javaid Akhtar Agro-climatology Laboratory Department of Agronomy University of Agriculture Faisalabad 38040 Pakistan Directorate of Agronomy Ayub Agricultural Research Institute (AARI) Faisalabad 38850 Pakistan Institute of Soil and Environmental Sciences University of Agriculture Faisalabad 38040 Pakistan

Climate change is making the lands a harsher environment all over the world including Pakistan. It is expected to oppose us with three main challenges： increase in temperature up to 2-5℃ （heat stress）, increasing water stress and severe malnourishment due to climate change. It has been foreseen that there will be a 10% increase of dryland areas with climate change in the world, with more variability and incidences of short periods of extreme events （drought and heat stress）. Pearl millet is a hardy, climate smart grain crop, idyllic for environments prone to drought and heat stresses. The crop continues to produce highly nutritious grain sustainably, thereby encouraging the fight against poverty and food insecurity due to its resilience. The crop is more responsive to good production options （planting time, planting density, inter/intra row spacing, nitrogen application and irrigation）. It has high crop growth rate, large leaf area index and high radiation use efficiency that confers its high potential yield. In most of the cases, pearl millet is remained our agricultural answer to the climate calamity that we are facing, because it is selected as water saving, drought tolerant and climate change complaint crop. In view of circumstances, pearl millet cultivation must be retrieved by recognizing production options in context to changing climate scenarios of Pakistan using crop modeling techniques.

关键词： pearl millet production options climate change nitrogen use efficiency radiation use efficiency

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Decoding degeneration:the implementation of machine learning for clinical detection of neurodegenerative disorders

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Neural Regeneration Research 2023年第6期18卷 1235-1242页

作者： Fariha khaliq Jane Oberhauser Debia Wakhloo Sameehan Mahajani Department of Biomedical Engineering and Sciences(BMES) National University of Science and TechnologyIslamabadPakistan Department of Neuropathology School of MedicineStanford UniversityStanfordCAUSA

Machine learning represents a growing subfield of artificial intelligence with much promise in the diagnosis,treatment,and tracking of complex conditions,including neurodegenerative disorders such as Alzheimer’s and Parkinson’s *** no definitive methods of diagnosis or treatment exist for either disease,researchers have implemented machine learning algorithms with neuroimaging and motion-tracking technology to analyze pathologically relevant symptoms and *** learning algorithms such as neural networks and complex combined architectures have proven capable of tracking disease-linked changes in brain structure and physiology as well as patient motor and cognitive symptoms and responses to ***,such techniques require further development aimed at improving transparency,adaptability,and *** this review,we provide an overview of existing neuroimaging technologies and supervised and unsupervised machine learning techniques with their current applications in the context of Alzheimer’s and Parkinson’s diseases.

关键词： Alzheimer’s disease clinical detection deep learning machine learning neurodegenerative disorders neuroimaging Parkinson’s disease

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Comparison of the effect of carbon,halloysite and titania nanotubes on the mechanical and thermal properties of LDPE based nanocomposite films

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Chinese Journal of Chemical Engineering 2018年第2期26卷 428-435页

作者： khaliq Majeed Mariam Al Ali AlMaadeed Moustafa M.Zagho Center for Advanced Materials Qatar UniversityPO Box 2713DohaQatar Department of Chemical Engineering COMSATS Institute olin formation TechnologyLahorePakistan Materials Science and Technology Program Qatar UniversityPO Box 2713DohaQatar

In this study, titania nanotubes （TNTs） were prepared by hydrothermal method with the aim to compare the properties of these one-dimensional tubular nanostructures＇ reinforced nanocomposites with the carbon and halloysite nanotubes＇（CNTs and HNTs, respectively） reinforced nanocomposites. Low density polyethylene （LDPE） was used as the matrix material. The prepared nanocomposites were characterized and compared by means of their morphological, mechanical and thermal properties. SEM results showed enhanced interracial interaction and better dispersion of TNTs and HNTs into LDPE with the incorporation of a MAPE compatibilizer, however, these interactions seem to be absent between CNTs and LDPE, and the CNTs remained agglomerated. Contact angle measurements revealed that CNT filled nanocomposites are more hydrophilic than HNT composites, and less than TNT composites. CNTs provided better tensile strength and Young＇s modulus than HNT and TNT nanocomposites, a 42% increase in tensile strength and Young＇s modulus is achieved compared to LDPE. Tear strength improvement was noticed in the TNT composites with a value of 35.4 N. mm -1, compared to CNT composites with a value of 25.5 *** 1 -s- 1. All the prepared nanocomposites are more thermally stable than neat LDPE and the best improvement in thermal stability was observed for CNT reinforced nanocomposites. CNTs depicted the best improvement in tensile and thermal properties and the MAPE compatibilizer effective- ness regarding morphological, mechanical and thermal properties was only observed for TNT and HNT systems.

关键词： Hydrothermal Nanostructure Nanotube Nanocomposite Mechanical properties Thermal properties

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Weed control through allelopathic crop water extracts and S-metolachlor in cotton

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Information Processing in Agriculture 2020年第1期7卷 165-172页

作者： Nadeem Iqbal Abdul khaliq Zahid Ata Cheema School of Agriculture and Food Science University of QueenslandBrisbane 4072Australia Depatment of Agronomy University of AgricultureFaisalabad 38040Pakistan

Weeds are one of the most important biological constraint to cotton production,and result-ing in a yield losses of up to 90%.The evolution of hundreds of resistant weed species,the lack of new herbicide chemistries,and the increase in weed management costs are all mak-ing weed management more arduous for the ***,a field experiment was con-ducted to investigate the efficacy of allelopathic crop water extracts(ACWEs)alone and in combinaton with one third rate of S-metolachlor 717g ***-1for effective weed man-agement in *** treatments investigated were;weedy check,sorghum+brassica water extract(WE)at 1.5Lha 1,sorghum+sunflower WE at 1.5Lha-,sorghum+bras-sica+sunflower WE at 1.5Lha-1,sorghum+brassica WE at 15L ha-1+S-metolachlor at 717 g ***-l,sorghum+sunflower WE at 1.5L ha-1+S-metolachlor at 717 g ***-1,sor-ghum+brassica WE+sunflower WE at 1.5Lha-1+S-metolachlor at 717 gaiha-,and S-metolachlor at recommended rate of 2.15 kg *** revealed that pre-emergent application of sorghum+brassica water extract(WE)at 1.5L ha-1 was the best treatment in terms of effective dry biomass reduction(40%)of Trianthema portulacastrum and Cyperus rotundus,and increase in seed cotton yield(12%).The second best treatment was sorghum+sunflower WE at 1.5Lha-1+S-metolachlor at 717g ***-1 with yield increase of 11%over the weedy *** comparison,S-metolachlor at recommended rate 2.15kg ***-1 recorded only 4%decrease in weeds dry biomass reduction and 8%increase in seed cotton ***,it can be predicted that binary combinaton of sorghum and brassica WE at 1.5 Lha-1 or binary combination of sorghum+sunflower WE at 15Lha-1 with one third dose of S-metolachlor (717g aiha-l)can be used for effective weed management and increase in seed cotton ***,adoption of this technique will also reduce the herbicide application,which is not only benefcial for the ecosystem but,also minimize the evolution of herbicide-resistant weed species.

关键词： Allelopathy Chemical weed control Herbicide Weeds Biomass Seed cotton yield Environment

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