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Effects of stem cells applications on oxidative stress and apoptosis during implantation

Asian pacific Journal of Reproduction 2018年第5期7卷 229-235页

作者： I■■l Aydemir Mahmud M.ozkut Fatma F■rat Alican Gümürüdü Dila Hatun Sal Kübra Erdogan asl■goker Mehmet■brahim Tuglu Department of Histology and Embryology Faculty of MedicineNi■de■mer Halisdemir University51240 Ni■deTurkey Department of Histology and Embryology Faculty of MedicineManisa Celal Bayar University45030 ManisaTurkey Izmir International Biomedicine and Genome Institute(IBG-Izmir) Dokuz Eylül University35340 IzmirTurkey Department of Neuroscience Health Science InstituteDokuz Eylül University35340 IzmirTurkey Department of Anatomy Faculty of MedicineIzmir Katip■elebi University35620 IzmirTurkey Department of Obstetrics and Gynecology Faculty of MedicineManisa Celal Bayar University45030 ManisaTurkey

Objective:To investigate the effects of bone marrow derived mesenchymal stem cell (BMSC) application into the rat endometrium on oxidative stress, cell proliferation and ***: The female rats selected in estrous cycle were divided into three groups (saline, media and BMSC group). The intrauterine and intraperitoneal injections were performed using the saline (200 μL), culture media (200 μL) and 1×106 BMSCs/200 μL culture media, and then they were mated with male rats. On the 7th day of the pregnancy, uterine samples were harvested and dyed with heamatoxylin-eosin histochemically, anti-endothelial nitric oxide synthase and anti-inducible nitric oxide synthase, and anti-proliferating cell nuclear antigen immunohistochemically, with terminal deoxynucleotidyl transferas dUTP nick end labeling for apoptosis. The stainings were evaluated by H-score and the results were analyzed using one-way ANOVA test ***: It was found that BMSCs increased the endometrial thickness, endometrial epithelium thickness and number of endometrial glands compared to control and sham groups. The intrauterine BMSC application decreased both anti-endothelial nitric oxide synthase and anti-inducible nitric oxide synthase immunoreactivities and the number of apoptotic cells compared to the intraperitoneal applications whereas the immunoreactivity of proliferating cell nuclear antigen was ***: In current study, we define that stem cells do not cause any structural damages. Also they change the distribution of oxidative stress and cell proliferation marker. These findings support the reliability of stem cells in clinical use in the case of infertility.

关键词： Mesenchymal stem cell Implantation Endometrium Oxidative stress Proliferation Apoptosis

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EFFECTS OF REACTION AND PROCESSING PARAMETERS ON ETHYLENE POLYMERIZATION USING DIFFERENT ZIEGLER-NATTA CATALYSTS:EMPLOYMENT OF TAGUCHI EXPERIMENTAL DESIGN AND RESPONSE SURFACE METHOD

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Chinese Journal of Polymer Science 2007年第2期25卷 153-162页

作者： Mohammad Najafi Vahid Haddadi-asl Polymer Engineering Department Amirkabir University of TechnologyP.O.Box 15875-4413TehranIran

Different Ziegler-Natta catalysts were employed to polymerize ethylene. To investigate the influences of reaction parameters, namely Al/Ti molar ratio, hydrogen and processing parameters, i.e. ethylene pressure and temperature, a Taguchi experimental design was worked out. An L27 orthogonal array was chosen to take the above-mentioned parameters and relevant interactions into account. Response surface method was the tool used to analyze the experimental design results. Al/Ti, ethylene pressure and temperature were selected as experimental design factors, and catalyst activity and polymerization yield were the response parameters. Increasing pressure, due to an increment in monomer accessibility, and rising Al/Ti, because of higher reduction in the catalysts, cause an increase in both polymerization yield and catalyst activity. Nonetheless, a higher temperature, thanks to reducing ethylene solubility in the slurry medium and partially catalyst destruction, lead to a reduction in both response parameters. A synergistic effect was also observed between temperature and pressure. All catalyst activities will reduce in the presence of hydrogen. Molecular weight also shows a decline in the presence of hydrogen as a transfer agent. However, the polydispersity index remains approximately intact. Using SEM, various morphologies, owing to different catalyst morphologies, were seen for the polyethylene.

关键词： L27 Taguchi experimental design Response surface method Polyethylene polymerization Ziegler-Natta catalysts.

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An Efficient Randomized Fixed-Precision Algorithm for Tensor Singular Value Decomposition

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Communications on Applied Mathematics and Computation 2023年第4期5卷 1564-1583页

作者： Salman Ahmadi-asl Skolkovo Institute of Science and Technology(SKOLTECH) Center for Artificial Intelligence TechnologyMoscowRussia

The existing randomized algorithms need an initial estimation of the tubal rank to compute a tensor singular value *** paper proposes a new randomized fixed-precision algorithm which for a given third-order tensor and a prescribed approximation error bound,it automatically finds the tubal rank and corresponding low tubal rank *** algorithm is based on the random projection technique and equipped with the power iteration method for achieving better *** conduct simulations on synthetic and real-world datasets to show the efficiency and performance of the proposed algorithm.

关键词： Tubal tensor decomposition Randomization Fixed-precision algorithm

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The amazing world of light nuclei

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Science Bulletin 2024年第21期69卷 3303-3304页

作者： aslıKuşoğlu Department of Physics Faculty of ScienceIstanbul UniversityVezneciler/Fatih34134 IstanbulTurkey

Light nuclei are few-body quantal systems and historically their spectra were theﬁrst to be studied *** a recent review,the existing experimental data from the stable N¼Z doubly-odd nuclei and spectroscopic studies have been discussed,as well as the b decay of the corresponding isobaric multiplets[1].The description of nuclear many-body systems derived fromﬁrst principles remains one of the most challenging research areas over the past decades because of the complex nature and limited knowledge of fundamental forces among nucleons,emerging from either meson-exchange theory or quantum chromodynamics(QCD).

关键词： meson decay spectroscopic

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Magnetic polyacrylonitrile/ZIF-8/Fe_(3)O_(4) nanocomposite bead as an efficient iodine adsorbent and antibacterial agent

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Chinese Journal of Chemical Engineering 2023年第9期61卷 210-220页

作者： Reza Sacourbaravi Zeinab Ansari-asl Esmaeil Darabpour Department of Chemistry Faculty of ScienceShahid Chamran University of AhvazAhvazIran Department of Biology Faculty of ScienceShahid Chamran University of AhvazAhvazIran

The efficient adsorption of radioactive iodine(^(129)I and^(131)I)as nuclear waste is of great *** nanocomposites consist of metal-organic frameworks(MOFs)developing for various pollutions sorption and separation have attracted much *** study reports the fabrication of magnetic polyacrylonitrile(PAN)/zeolitic imidazolate frameworks(ZIF-8)nanocomposites,PAN/ZIF-8(x%)/Fe_(3)O_(4),x=30 and 50,as iodine capture *** PAN/ZIF-8(x%)/Fe_(3)O_(4)nanocomposite beads were fabricated via the phase inversion method,and their potential for iodine capture and separation in solution and vapor was investigated through UV-vis and weighing methods,***,antibacterial activity of the as-prepared beads was assessed against *** and *** as-fabricated compounds were studied by various techniques such as Fourier-transform infrared,X-ray diffraction,scanning electron microscope,energy-dispersive X-ray spectroscopy mapping,transmission electron microscope,N_(2)adsorption isotherm,and vibrating sample *** iodine capture results showed that the efficiency of nanocomposites is remarkably higher than the pure PAN ***,the asprepared nanocomposite adsorbents displayed higher capture capacities for iodine vapor(1524-4345mg·g^(-1))than iodine solution(187-295 mg·g^(-1)).The as-obtained magnetic nanocomposites can be successfully separated from polluted media by simple filtration or an external magnet,regenerated through washing with ethanol,and *** capturing,high sorption capacity,rapid separation,and good reusability make the PAN/ZIF-8(x%)/Fe_(3)O_(4)nanocomposites highly effective adsorbents for the separation of iodine from ***,PAN/ZIF-8(50%)/Fe_(3)O_(4)bead can be considered as a potential new antibacterial agent for water and wastewater treatment.

关键词： ZIF-8 Polyacrylonitrile Composites Adsorption Waste treatment Antibacterial agent

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Protein adsorption, cell viability and corrosion properties of Ti6Al4V alloy treated by plasma oxidation and anodic oxidation

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International Journal of Minerals,Metallurgy and Materials 2020年第9期27卷 1269-1280页

作者： ÖzgüBayrak Hojjat Ghahramanzadeh asl Ayşe Ak Department of Mechanical Engineering Erzincan Binali Yıldırım UniversityErzincan 24100Turkey Department of Mechanical Engineering Karadeniz Technical UniversityTrabzon 61080Turkey Vocational School of Health Services Medical Imaging Techniques ProgrammeKocaeli UniversityKocaeli 41001Turkey

The hardness,wettability,and electrochemical properties of Ti6Al4V alloy surfaces treated with anodic oxidation and plasma oxidation as well as the viabilities of the different cell lines on the obtained surfaces were *** anodic oxidation was performed for 10 min under 100 V potential,and it resulted in a 0.95μm thick nanoporous anatase-TiO2 *** the other hand,plasma oxidation was carried out at 650℃ for 1 h and resulted in a dense rutile-TiO2 structure with a thickness of 1.2μ*** a hardness of HV0.025823 and roughness of^220 nm were obtained by plasma oxidation,those obtained by anodic oxidation were HV0.025512 and^130 nm,*** anodic oxidation process created a more hydrophilic surface with a contact angle of 87.2°.Both oxidation processes produced similar properties in terms of corrosion behavior and showed better resistance than the as-received state in a certain range of ***,the surface treatments led to no significant change in the protein adsorption levels,which indicates that the difference in viability between the osteoblast and fibroblast cells was not due to the difference in surface protein *** all the factors,the surfaces obtained by anodic oxidation treatment revealed higher cell viability than those obtained by plasma oxidation(p=0.05).

关键词： Ti6Al4V oxidation corrosion cell viability protein adsorption

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Operation and Flexibility Contribution of Natural Gas Tanks in Multi-carrier Energy Systems

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CSEE Journal of Power and Energy Systems 2021年第3期7卷 622-631页

作者： Alireza Hamedi Ali Reza Seifi Dariush Keihan asl School of Electrical and Computer Engineering Shiraz UniversityShirazIran

Energy storage systems(ESSs)have an assistive role in the operation of multi-carrier energy *** paper presents a type of natural gas(NG)ESS called NG tank and studies the operation and flexibility contributions of this ESS in the *** tank modeling and formulation are unified the same as the electrical *** NG tank and the electrical ESS models are implemented on a large-scale multi-carrier energy network and the impressive effects of utilizing these units are investigated in the operational planning of the energy *** optimal operational problem is solved utilizing the teaching learning based optimization(TLBO)algorithm to minimize the operational cost of the system.

关键词： Electrical ESS multi-carrier energy system NG tank optimal operation

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FSPAM:A Feature Construction Method to Identifying Cell Populations in ScRNA-seq Data

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Computer Modeling in Engineering & Sciences 2020年第1期122卷 377-397页

作者： Amin Einipour Mohammad Mosleh Karim Ansari-asl Department of Computer Engineering Dezful BranchIslamic Azad UniversityDezfulIran Department of Electrical Engineering Faculty of EngineeringShahid Chamran University of AhvazAhvazIran

The emergence of single-cell RNA-sequencing(scRNA-seq)technology has introduced new information about the structure of cells,diseases,and their associated biological *** of the main uses of scRNA-seq is identifying cell populations,which sometimes leads to the detection of rare cell ***,the new method is still in its infancy and with its advantages comes computational challenges that are just beginning to *** important tool in the analysis is dimensionality reduction,which transforms high dimensional data into a meaningful reduced *** technique allows noise removal,visualization and compression of high-dimensional *** paper presents a new dimensionality reduction approach where,during an unsupervised multistage process,a feature set including high valuable markers is created which can facilitate the isolation of cell *** proposed method,called fusion of the Spearman and Pearson affinity matrices(FSPAM),is based on a graph-based Gaussian *** of the graph theory can be effective to overcome the challenge of the nonlinear relations between cellular markers in scRNA-seq ***,with a proper fusion of the Pearson and Spearman correlation coefficient criteria,it extracts a set of the most important features in a new *** fact,the FSPAM aggregates the various aspects of cell-to-cell similarity derived from the Pearson and Spearman metrics,and reveals new aspects of cell-to-cell similarity,which can be used to extract new *** results of the identification of cell populations via k-means++clustering method based on the features extracted from the FSPAM and different datasets of scRNA-seq suggested that the proposed method,regardless of the characteristics that govern each dataset,enjoys greater accuracy and better quality compared to previous methods.

关键词： Single cell RNA sequencing cell population feature extraction fusion

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Problems of Lifts in Symplectic Geometry

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Chinese Annals of Mathematics,Series B 2019年第3期40卷 321-330页

作者： Arif SALIMOV Manouchehr BEHBOUDI asl Sevil KAZIMOVA Department of Algebra and Geometry Baku State University Department of Mathematics Salmas Branch Islamic Azad University

Let(M,ω)be a symplectic *** this paper,the authors consider the notions of musical(bemolle and diesis)isomorphisms ω~b:T M→T~*M and ω~?:T~*M→TM between tangent and cotangent *** authors prove that the complete lifts of symplectic vector field to tangent and cotangent bundles is ω~*** consequence of analyze of connections between the complete lift ~cω_(T M )of symplectic 2-form ω to tangent bundle and the natural symplectic 2-form dp on cotangent bundle,the authors proved that dp is a pullback o f^cω_(TM)by ω~?.Also,the authors investigate the complete lift ~cφ_T~*_M )of almost complex structure φ to cotangent bundle and prove that it is a transform by ω~?of complete lift^cφ_(T M )to tangent bundle if the triple(M,ω,φ)is an almost holomorphic *** transform of complete lifts of vector-valued 2-form is also studied.

关键词： Symplectic manifold Tangent bundle Cotangent bundle Transform of tensor fields Pullback Pure tensor Holomorphic manifold

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GenFloor:Interactive generative space layout system via encoded tree graphs

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Frontiers of Architectural Research 2021年第4期10卷 771-786页

作者： Mohammad Keshavarzi Mohammad Rahmani-asl Department of Architecture University of CaliforniaBerkeleyCAUSA Autodesk Inc. San FranciscoCAUSA

Automated floorplanning or space layout planning has been a long-standing NP-hard problem in the field of computer-aided design,with applications in integrated circuits,architecture,urbanism,and operational *** this paper,we introduce GenFloor,an interactive design system that takes geometrical,topological,and performance goals and constraints as input and provides optimized spatial design solutions as *** part of our work,we propose three novel permutation methods for existing space layout graph representations,namely O-Tree and B*-Tree *** implement our proposed floorplanning methods as a package for Dynamo,a visual programming tool,with a custom GUI and additional evaluation functionalities to facilitate designers in their generative design ***,we illustrate the performance of GenFloor in two sets of case-study experiments for residential floorplanning tasks by(a)measuring the ability of the proposed system to find a known optimal solution,and(b)observing how the system can generate diverse floorplans while addressing given a constant residential design *** results indicate that convergence to the global optimum is achieved while offering a diverse set of solutions of a residential floorplan corresponding to local optimums of the solution landscape.

关键词： Generative design Floorplanning Optimization Space layout Performance-based design Optioneering

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