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Characterization of tumors of jaw:Additive value of contrast enhancement and dual-energy computed tomography

World Journal of Radiology 2024年第4期16卷 82-93页

作者： Deepak Justine Viswanathan Ashu Seith Bhalla Smita Manchanda Ajoy Roychoudhury Deepika Mishra asit ranjan mridha Department of Radiodiagnosis and Interventional Radiology All India Institute of Medical SciencesNew Delhi 110029India Department of Oral and Maxillofacial Surgery All India Institute of Medical SciencesNew Delhi 110029India Department of Oral Pathology and Microbiology All India Institute of Medical SciencesNew Delhi 110029India Department of Pathology All India Institute of Medical SciencesAnsari NagarNew Delhi 110029India

BACKGROUND Currently,the differentiation of jaw tumors is mainly based on the lesion’s morphology rather than the enhancement characteristics,which are important in the differentiation of neoplasms across the body.There is a paucity of literature on the enhancement characteristics of jaw tumors.This is mainly because,even though computed tomography(CT)is used to evaluate these lesions,they are often imaged without intravenous contrast.This study hypothesised that the enhancement characteristics of the solid component of jaw tumors can aid in the differentiation of these lesions in addition to their morphology by dual-energy CT,therefore improving the ability to differentiate between various pathologies.AIM To evaluate the role of contrast enhancement and dual-energy quantitative parameters in CT in the differentiation of jaw tumors.METHODS Fifty-seven patients with jaw tumors underwent contrast-enhanced dual-energy CT.Morphological analysis of the tumor,including the enhancing solid component,was done,followed by quantitative analysis of iodine concentration(IC),water concentration(WC),HU,and normalized IC.The study population was divided into four subgroups based on histopathological analysis-central giant cell granuloma(CGCG),ameloblastoma,odontogenic keratocyst(OKC),and other jaw tumors.A one-way ANOVA test for parametric variables and the Kruskal-Wallis test for nonparametric variables were used.If significant differences were found,a series of independent t-tests or Mann-Whitney U tests were used.RESULTS Ameloblastoma was the most common pathology(n=20),followed by CGCG(n=11)and OKC.CGCG showed a higher mean concentration of all quantitative parameters than ameloblastomas(P<0.05).An IC threshold of 31.35×100μg/cm^(3) had the maximum sensitivity(81.8%)and specificity(65%).Between ameloblastomas and OKC,the former showed a higher mean concentration of all quantitative parameters(P<0.001),however when comparing unilocular ameloblastomas with OKCs,the latter showed significantly higher WC.Also,ameloblastoma had

关键词： Jaw neoplasms Ameloblastomas Dual-energy computed tomography Iodine quantification Mandibular neoplasms Maxillary neoplasms

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Contrast-enhanced multidetector computed tomography features and histogram analysis can differentiate ameloblastomas from central giant cell granulomas

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World Journal of Radiology 2022年第9期14卷 329-341页

作者： Adarsh Ghosh Meyyappan Lakshmanan Smita Manchanda Ashu Seith Bhalla Prem Kumar Ongkila Bhutia asit ranjan mridha Department of Radiology Children's Hospital of PhiladelphiaPhiladelphiaPA 19104United States Department of Radiology All India Institute of Medical SciencesNew Delhi 110029India Department of Radiodiagnosis All India Institute of Medical SciencesNew Delhi 110029India Department of Oral&Maxillofacial Surgery All India Institute of Medical SciencesNew Delhi 110029India Department of Pathology All India Institute of Medical SciencesAnsari NagarNew Delhi 110029India

BACKGROUND No qualitative or quantitative analysis of contrast-enhanced computed tomography(CT)images has been reported for the differentiation between ameloblastomas and central giant cell granulomas(CGCGs).AIM To describe differentiating multidetector CT(MDCT)features in CGCGs and ameloblastomas and to compare differences in enhancement of these lesions qualitatively and using histogram analysis.METHODS MDCT of CGCGs and ameloblastomas was retrospectively reviewed to evaluate qualitative imaging descriptors.Histogram analysis was used to compare the extent of enhancement of the soft tissue.Fisher’s exact tests and Mann–Whitney U test were used for statistical analysis(P49.05 HU in the tumour providing 100%sensitivity and 85%specificity in identifying a CGCG.CONCLUSION A multilocular,lytic sclerotic lesion with significant hyperenhancement in soft tissue,which spares the angle of the mandible and has matrix mineralization,should indicate prospective diagnosis of CGCG.

关键词： Ameloblastoma Granuloma Giant cell Multidetector CT

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Intraparotid facial nerve schwannoma: A case report

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World Journal of Clinical Cases 2015年第3期3卷 322-326页

作者： Abhishek Jaiswal asit ranjan mridha Devajit Nath Ashu Seith Bhalla Alok Thakkar Department of Radiodiagnosis All India Institute Of Medical Sciences AIIMS Department of Pathology AIIMS Department of Otolaryngology and Rhinology AIIMS

Facial nerve schwannoma occurring within the parotid gland is a rare tumour. We report a case of schwannoma within the parotid gland in a young female patient, who underwent ultrasound and magnetic resonanceimaging(MRI) and subsequent surgical excision of the lesion. The lesion showed hyperintensity on T2-weighted and diffusion-weighted MRI. There was no adjacent lymphadenopathy. Although hyperintensity on diffusionweighted MRI could suggest malignant tumours, the characteristic "string sign" provided the clue for the diagnosis of schwannoma.

关键词： Parotid Facial nerve Schwannoma String sign Imaging

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Unusual presentation of Erdheim-Chester disease in a child with acute lymphoblastic leukemia

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World Journal of Radiology 2016年第8期8卷 757-763页

作者： Archana George Vallonthaiel asit ranjan mridha Shivanand Gamanagatti Manisha Jana Mehar Chand Sharma Shah Alam Khan Sameer Bakhshi Department of Pathology All India Institute of Medical Sciences Department of Radiodiagnosis All India Institute of Medical Sciences Department of Orthopaedics All India Institute of Medical Sciences Medical Oncology All India Institute of Medical Sciences

Erdheim-Chester disease(ECD) is an uncommon, nonfamilial, non-Langerhans cell histiocytosis, which involves skeletal system and soft tissue usually in middle aged and elderly patients. The characteristic radiologic features include bilateral, symmetric cortical osteosclerosis of the diaphyseal and metaphyseal parts of the long bones, or bilateral symmetrically abnormal intense 99 mTechnetium labelling of the metaphyseal-diaphyseal region of the long bones, and computed tomography scan findings of "coated aorta" or "hairy kidneys". ECD in childhood with osteolytic lesion is extremely rare. We describe an unusual case with an expansile lytic bone lesion at presentation in a case of acute lymphoblastic leukemia.

关键词： Erdheim-Chester disease Osteolytic lesion Bone Acute lymphoblastic leukemia

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Investigation of proton structure function F_(2)^(p)at HERA in light of an analytical solution to the Balitsky–Kovchegov equation

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Communications in Theoretical Physics 2024年第3期76卷 120-126页

作者： ranjan Saikia Pragyan Phukan Jayanta Kumar Sarma HEP laboratory Department of PhysicsTezpur UniversityTezpurAssam-784028India Department of Physics Moran CollegeMoranhatAssam-785670India

In this paper,the proton structure function F_(2)^(p)(x,Q^(2))at small-x is investigated using an analytical solution to the Balitsky–Kovchegov(BK)equation.In the context of the color dipole description of deep inelastic scattering(DIS),the structure function F_(2)^(p)(x,Q^(2))is computed by applying the analytical expression for the scattering amplitude N(k,Y)derived from the BK solution.At transverse momentum k and total rapidity Y,the scattering amplitude N(k,Y)represents the propagation of the quark-antiquark dipole in the color dipole description of DIS.Using the BK solution we extracted the integrated gluon density xg(x,Q^(2))and then compared our theoretical estimation with the LHAPDF global data fits,NNPDF3.1sx and CT18.Finally,we have investigated the behavior of F_(2)^(p)(x,Q^(2))in the kinematic region of 10^(-5)≤x≤10^(-2)and 2.5 GeV^(2)≤Q^(2)≤60 GeV^(2).Our predicted results for F_(2)^(p)(x,Q^(2))within the specified kinematic region are in good agreement with the recent high-precision data for F_(2)^(p)(x,Q^(2))from HERA(H1 Collaboration)and the LHAPDF global parametrization group NNPDF3.1sx.

关键词： quantum chromodynamics(QCD) perturbative QCD(pQCD) proton structure function small-x Balitsky-Kovchegov equation

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Doppler-resilient waveform design in integrated MIMO radar-communication systems

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Science China(Information Sciences) 2024年第1期67卷 187-202页

作者： Zhengchun ZHOU Bing LIU Bingsheng SHEN Avik ranjan ADHIKARY Pingzhi FAN Institute of Mobile Communications Southwest Jiaotong University Department of Mathematics Southwest Jiaotong University

In recent years,the increased high-rate wireless services(5G and 6G) and reliable sensing capabilities(automotive radar,air traffic control,geophysical monitoring),have led to more serious spectrum congestion.Conventionally,radars and communication systems are often seen to be “competing” for the same resources.In this scenario,an integrated platform for radar and communication systems seems to be an optimal solution to address the problem.In this paper,we propose a preamble waveform design based on zero-correlation zone(ZCZ) and zero odd-correlation zone(ZOCZ) sequence sets,which are Doppler resilient in multiple-input,multiple-output(MIMO) radar.The preamble waveforms can be simultaneously used for channel estimation and radar sensing in RadCom systems.The ambiguity function of the proposed waveforms displays low/zero sidelobes within a time-delay correlation zone.Finally,we give some numerical results to show the efficiency of the proposed waveforms in radar sensing and channel estimation.

关键词： ambiguity function correlation channel estimation integrated radar and communication (RadCom) systems MIMO radar zero correlation zone (ZCZ) sequence set zero odd-correlation zone (ZOCZ) sequence set

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Sodium glucose cotransporter-2 inhibitors and heart disease:Current perspectives

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World Journal of Cardiology 2024年第5期16卷 240-259页

作者： Sunetra Mondal Subhodip Pramanik Vibhu ranjan Khare Cornelius James Fernandez Joseph M Pappachan Department of Endocrinology NRS Medical CollegeKolkata 700020West BengalIndia Department of Endocrinology Neotia Getwel Multispecialty HospitalsSiliguri 734010West BengalIndia Department of Endocrinology and Metabolism Pilgrim HospitalUnited Lincolnshire Hospitals NHS TrustBoston PE219QSUnited Kingdom Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine&HealthThe University of ManchesterManchester M139PLUnited Kingdom

Sodium glucose cotransporter-2 inhibitors(SGLT-2i)are antidiabetic medications with remarkable cardiovascular(CV)benefits proven by multiple randomised controlled trials and real-world data.These drugs are also useful in the prevention of CV disease(CVD)in patients with diabetes mellitus(DM).Although DM as such is a huge risk factor for CVD,the CV benefits of SGLT-2i are not just because of antidiabetic effects.These molecules have proven beneficial roles in prevention and management of nondiabetic CVD and renal disease as well.There are various molecular mechanisms for the organ protective effects of SGLT-2i which are still being elucidated.Proper understanding of the role of SGLT-2i in prevention and management of CVD is important not only for the cardiologists but also for other specialists caring for various illnesses which can directly or indirectly impact care of heart diseases.This clinical review compiles the current evidence on the rational use of SGLT-2i in clinical practice.

关键词： SGLT2 inhibitors SGLT2i Cardiovascular disease Heart failure Atherosclerotic cardiovascular disease Diabetic kidney disease

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Efficacy of stromal vascular fraction for knee osteoarthritis:A prospective,single-centre,non-randomized study with 2 years follow-up

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World Journal of Orthopedics 2024年第5期15卷 457-468页

作者： Madhan Jeyaraman Naveen Jeyaraman Tarun Jayakumar Swaminathan Ramasubramanian Rajni ranjan Saurabh Kumar Jha Ashim Gupta Department of Orthopaedics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennaiTamil Nadu 600077India Department of Biotechnology School of Engineering and TechnologySharda UniversityGreater NoidaUttar Pradesh 201310India Department of Orthopaedics and Regenerative Medicine South Texas Orthopaedic Research InstituteLaredoTX 78045United States Department of Orthopaedics KIMS-Sunshine HospitalHyderabadTelangana 500032India Department of Orthopaedics Government Medical CollegeOmandurar Government EstateChennaiTamil Nadu 600002India Department of Orthopaedics School of Medical Sciences and ResearchSharda UniversityGreater NoidaUttar Pradesh 201306India Department of Zoology Kalindi CollegeUniversity of DelhiNew Delhi 110008India Department of Orthopaedics and Regenerative Medicine Regenerative OrthopaedicsNoida 201301Uttar PradeshIndia Department of Orthopaedics and Regenerative Medicine Future BiologicsLawrencevilleGA 30043United States Department of Orthopaedics and Regenerative Medicine BioIntegrateLawrencevilleGA 30043United States

BACKGROUND Current osteoarthritis(OA)treatments focus on symptom relief without addressing the underlying disease process.In regenerative medicine,current treatments have limitations.In regenerative medicine,more research is needed for intra-articular stromal vascular fraction(SVF)injections in OA,including dosage optimization,long-term efficacy,safety,comparisons with other treatments,and mechanism exploration.AIM To compare the efficacy of intra-articular SVF with corticosteroid(ICS)injections in patients with primary knee OA.METHODS The study included 50 patients with Kellgren-Lawrence grades II and III OA.Patients were randomly assigned(1:1)to receive either a single intra-articular SVF injection(group A)or a single intra-articular ICS(triamcinolone)(group B)injection.Patients were followed up at 1,3,6,12,and 24 months.Visual analog score(VAS)and International Knee Documentation Committee(IKDC)scores were administered before the procedure and at all followups.The safety of SVF in terms of adverse and severe adverse events was recorded.Statistical analysis was performed with SPSS Version 26.0,IBM Corp,Chicago,IL,United States.RESULTS Both groups had similar demographics and baseline clinical characteristics.Follow-up showed minor patient loss,resulting in 23 and 24 in groups A and B respectively.Group A experienced a notable reduction in pain,with VAS scores decreasing from 7.7 to 2.4 over 24 months,compared to a minor reduction from 7.8 to 6.2 in Group B.This difference in pain reduction in group A was statistically significant from the third month onwards.Additionally,Group A showed significant improvements in knee functionality,with IKDC scores rising from 33.4 to 83.10,whereas Group B saw a modest increase from 36.7 to 45.16.The improvement in Group A was statistically significant from 6 months and maintained through 24 months.CONCLUSION Our study demonstrated that intra-articular administration of SVF can lead to reduced pain and improved knee function in patients with primary knee OA.More adequately powe

关键词： Knee osteoarthritis Adipose tissue Stromal vascular fraction Regenerative medicine Orthobiologics

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Improving Heat Transfer in Parabolic Trough Solar Collectors by Magnetic Nanofluids

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Energy Engineering 2024年第4期121卷 835-848页

作者： Ritesh Singh Abhishek Gupta Akshoy ranjan Paul Bireswar Paul Suvash C.Saha Department of Applied Mechanics Motilal Nehru National Institute of Technology AllahabadPrayagrajIndia Department of Mechanical and Mechatronic Engineering University of Technology SydneySydneyAustralia

A parabolic trough solar collector(PTSC)converts solar radiation into thermal energy.However,low thermal efficiency of PTSC poses a hindrance to the deployment of solar thermal power plants.Thermal performance of PTSC is enhanced in this study by incorporating magnetic nanoparticles into the working fluid.The circular receiver pipe,with dimensions of 66 mm diameter,2 mm thickness,and 24 m length,is exposed to uniform temperature and velocity conditions.The working fluid,Therminol-66,is supplemented with Fe3O4 magnetic nanoparticles at concentrations ranging from 1%to 4%.The findings demonstrate that the inclusion of nanoparticles increases the convective heat transfer coefficient(HTC)of the PTSC,with higher nanoparticle volume fractions leading to greater heat transfer but increased pressure drop.The thermal enhancement factor(TEF)of the PTSC is positively affected by the volume fraction of nanoparticles,both with and without a magnetic field.Notably,the scenario with a 4%nanoparticle volume fraction and a magnetic field strength of 250 G exhibits the highest TEF,indicating superior thermal performance.These findings offer potential avenues for improving the efficiency of PTSCs in solar thermal plants by introducing magnetic nanoparticles into the working fluid.

关键词： Parabolic trough solar collector(PTSC) magnetic nanofluid(MNF) heat transfer convective heat transfer coefficient(HTC) thermal enhancement factor(TEF)

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Erosive Wear Study of PPLSF/Glass Fiber Reinforced Hybrid Laminates

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Journal of Harbin Institute of Technology(New Series) 2024年第2期31卷 68-79页

作者： Chetana Tripathy Deepak Kumar Mohapatra Chitta ranjan Deo Punyapriya Mishra Department of Mechanical Engineering Veer Surendra Sai University of Technology(VSSUT)Sambalpur 768018India

This work is focused to examine the erosive performance of hybrid Palmyra palm leaf stalk fiber(PPLSF)/glass polyester laminate against solid particle bombardment.A hand lay-up method was adopted for the fabricating four piles of five distinct laminates with different stacking order glass and PPLSF layers.Amongst them,one group of pure PPLSF and pure E-glass laminates were fabricated.The hybrid laminates were exposed to high speed stream of solid sand particle at three distinct impact velocities(48,70 and 82 m/s)and four different angles of impingement(30°,45°,60°and 90°).The effect of particle velocity,angle of impingement and stacking order on both wear rate and efficiency were highlighted.The experimental assessment reveals a significant improvement in erosive wear resistance properties due to hybridization of PPLSF with E-glass.Again,the laminates with PPLSF layer as skin and glass as core layer exhibited better erosive wear resistance properties than other types of laminates.Further,a maximum value of erosion at lower velocity(48 m/s)is also noticed at 45°impingement angle.However,at high velocity of impact 70 m/s and 82 m/s,the maximum rate of erosion has been shifted from 45°impact angle to 60°impact angle.The alternation of this semi-ductile character to semi-brittle character is evidenced by analyzing the experimental data.Further to justify the mode of erosion,the eroded surface samples were inspected by scanning electron microscope(SEM).

关键词： hybrid composites erosion wear void micro-hardness SEM

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